Department of Molecular Cell Biology

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Dr. Leeat Yankielowicz-Keren
Systems tissue pathology

Prof. Shalev Itzkovitz
Systems Biology of Mammalian Tissues

Prof. Yonatan Stelzer
Epigenetics in development and disease

Prof. Ravid Straussman
The study of resistance to anti-cancer therapy

Prof. Yardena Samuels
Melanoma Functional Genomics

Prof. Valery Krizhanovsky
Cellular senescence in tissue damage cancer and aging

Prof. Oren Schuldiner
Mechanisms of neuronal remodeling

Prof. Eran Segal
Developing Computational Models for Personalized Medicine

Prof. Sima Lev
Cell Signaling in Cancer Development and Metastasis

Prof. Gil Levkowitz
Linking genes, development and function of the zebrafish hypothalamus

Prof. Itay Tirosh
Tumor Systems Biology

Prof. Yehiel Zick
Cross talk between insulin resistance, animal lectins and bone remodeling

Prof. Elior Peles
Development of myelinated nerves

Prof. Moshe Oren
Molecular and cellular biology of cancer

Prof. Eldad Tzahor
Cardiomyocyte cell-cycle control and dedifferentiation

Prof. Varda Rotter
The role of p53 in maintaining genomic plasticity

Prof. Uri Alon
Systems biology and physics of behavior

Research in our department centers around molecular mechanisms that control different aspects of cell biology during development and disease states. Large part of the research focuses on cancer heterogeneity at both genomics, proteomics, and the cancer microbiome. We bring unique and innovative research approaches that shed light on organ function in vivo, such as heart, liver, pancreas, gut, and the nervous system. Studies at the department explore diverse cell biology topics including cell-cell communication, cytoskeletal organization; intracellular signaling; senescence, differentiation; physiology and metabolism.

Latest PUBLICATIONS

Heritability of intrinsic human life span is about 50% when confounding factors are addressed

Shenhar B., Pridham G., De Oliveira T. L., Raz N., Yang Y., Deelen J., Hägg S. & Alon U. (2026), Science. 391, 6784, p. 504-510

From Plato to Pareto: Defining the shape of infection's disease space

Lebel Y., Gupta A. S., Chevée V., Alon U. & Schneider D. S. (2026), Science Advances. 12, 5, eaeb3911

Temporal tissue dynamics from a spatial snapshot

Somer J., Mannor S. & Alon U. (2026), Nature

Localization of Asgard archaeal ESCRT proteins to eukaryotic cellular structures

Naripogu K. B., Tee Y. H., Senju Y., Bershadsky A. & Robinson R. C. (2026), Biochemical and Biophysical Research Communications. 802, 153301

The legacy of a gentleman scientist: Pierre Hainaut

Arnoult C., Attardi L. D., Batsheva K., Blandino G., Burns K. H., Del Sal G., Kirsch D. G., Lane D. P., Levine A. J., Lozano G., Malkin D., Melino G., Oren M., Prives C. & Schramek D. (2026), Cell Death and Differentiation. 33, 1, p. 1-2

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news

Date: February 5, 2026

Congratulations to Prof. Uri Alon

IUPAP Medal for the Physics of Life.
Read more about Congratulations to Prof. Uri Alon
Date: January 15, 2026

Congratulations to Prof. Oren Schuldiner

TUM Ambassador
Date: January 8, 2026

Congratulations to Prof. Ravid Straussman

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