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Endosomal protein that interacts with phospholipid flippase Drs2p; interaction with Cdc50p is essential for Drs2p catalytic activity; mutations affect cell polarity and polarized growth; similar to Ynr048wp and Lem3p
Localization:
Intensity:
Fold change:
Significance:
-
C’ GFP library in SD
punctate29.29 -
N' NOP1pr-GFP in SD
ER,punctate82.4156 -
N' TEF2pr-mCherry in SD
ER,vacuole73.2377 -
N' NATIVEpr-GFP in SD
punctate27.1915 -
N' TEF2pr-VC and Cyto-VN in SD
cytosol,punctate34.2465 -
C’ GFP library in SD+DTT
punctate34.431.17No -
C’ GFP library in SD+H2O2
punctate32.591.11No -
C’ GFP library in Starvation Media
punctate44.621.52Yes -
C’ GFP library on the background of Pup2-DaMP
punctate -
C’ GFP library on the background of CCT mutant
punctate35.64731.21662No