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Uroporphyrinogen decarboxylase, catalyzes the fifth step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; a hem12 mutant has phenotypes similar to patients with porphyria cutanea tarda
Localization:
Intensity:
Fold change:
Significance:
  • C’ GFP library in SD
    YDR047W
    cytosol
    40.15
  • N' NOP1pr-GFP in SD
    YDR047W
    cytosol
    176.372
  • N' TEF2pr-mCherry in SD
    YDR047W
    cytosol
    291.22
  • N' NATIVEpr-GFP in SD
    YDR047W
    cytosol
    56.2839
  • N' TEF2pr-VC and Cyto-VN in SD
    YDR047W
    cytosol
    72.0557
  • C’ GFP library in SD+DTT 
    YDR047W
    cytosol
    23.67
    0.58
    Yes
  • C’ GFP library in SD+H2O2
    YDR047W
    cytosol
    45.38
    1.13
    No
  • C’ GFP library in Starvation Media
    YDR047W
    cytosol
    70.68
    1.75
    Yes
  • C’ GFP library on the background of Pup2-DaMP
    noimage.png
    cytosol
  • C’ GFP library on the background of CCT mutant
    noimage.png
    cytosol
    50.9054
    1.26735
    No