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Cytoplasmic tyrosyl-tRNA synthetase, required for cytoplasmic protein synthesis; interacts with positions 34 and 35 of the tRNATyr anticodon; mutations in human ortholog YARS are associated with Charcot-Marie-Tooth (CMT) neuropathies
Localization:
Intensity:
Fold change:
Significance:
  • C’ GFP library in SD
    YGR185C
    below threshold
    16.49
  • N' NOP1pr-GFP in SD
    YGR185C
    cytosol
    246.614
  • N' TEF2pr-mCherry in SD
    YGR185C
    cytosol
    352.073
  • N' NATIVEpr-GFP in SD
    YGR185C
    below threshold
    20.0591
  • N' TEF2pr-VC and Cyto-VN in SD
    noimage.png
    #N/A
    0
  • C’ GFP library in SD+DTT 
    YGR185C
    cytosol
    14.83
    0.89
    No
  • C’ GFP library in SD+H2O2
    YGR185C
    cytosol
    17.24
    1.04
    No
  • C’ GFP library in Starvation Media
    YGR185C
    cytosol
    27.23
    1.65
    No
  • C’ GFP library on the background of Pup2-DaMP
    noimage.png
    below threshold
  • C’ GFP library on the background of CCT mutant
    noimage.png
    below threshold
    16.8436
    1.02079
    No