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Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; homolog of mammalian INSIG proteins
Localization:
Intensity:
Fold change:
Significance:
  • C’ GFP library in SD
    YHR133C
    below threshold
    14.03
  • N' NOP1pr-GFP in SD
    YHR133C
    ER
    188.43
  • N' TEF2pr-mCherry in SD
    YHR133C
    ER
    193.146
  • N' NATIVEpr-GFP in SD
    YHR133C
    cell periphery,punctate
    50.8049
  • N' TEF2pr-VC and Cyto-VN in SD
    YHR133C
    ER
    51.7944
  • C’ GFP library in SD+DTT 
    YHR133C
    cytosol
    13.89
    0.98
    No
  • C’ GFP library in SD+H2O2
    YHR133C
    cytosol
    15.55
    1.1
    No
  • C’ GFP library in Starvation Media
    YHR133C
    cytosol
    15.25
    1.08
    No
  • C’ GFP library on the background of Pup2-DaMP
    noimage.png
    N/A
  • C’ GFP library on the background of CCT mutant
    noimage.png
    N/A
    0
    N/A
    Yes