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Component of the commitment complex, which defines the first step in the splicing pathway; essential protein that interacts with Mud2p and Prp40p, forming a bridge between the intron ends; also involved in nuclear retention of pre-mRNA
Localization:
Intensity:
Fold change:
Significance:
-
C’ GFP library in SD
below threshold14.69 -
N' NOP1pr-GFP in SD
nucleus37.7368 -
N' TEF2pr-mCherry in SD
nucleus24.7613 -
N' NATIVEpr-GFP in SD
punctate,nucleus24.5775 -
N' TEF2pr-VC and Cyto-VN in SD
#N/A0 -
C’ GFP library in SD+DTT
cytosol18.421.25No -
C’ GFP library in SD+H2O2
cytosol16.41.11No -
C’ GFP library in Starvation Media
cytosol15.061.02No -
C’ GFP library on the background of Pup2-DaMP
below threshold -
C’ GFP library on the background of CCT mutant
below threshold17.30811.17729No