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Component of the hexameric MCM complex, which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase
Localization:
Intensity:
Fold change:
Significance:
-
C’ GFP library in SD
below threshold16.83 -
N' NOP1pr-GFP in SD
nucleus53.3269 -
N' TEF2pr-mCherry in SD
missing0 -
N' NATIVEpr-GFP in SD
missing0 -
N' TEF2pr-VC and Cyto-VN in SD
#N/A0 -
C’ GFP library in SD+DTT
cytosol15.770.93No -
C’ GFP library in SD+H2O2
cytosol16.891No -
C’ GFP library in Starvation Media
cytosolN/AN/AYes -
C’ GFP library on the background of Pup2-DaMP
below threshold -
C’ GFP library on the background of CCT mutant
below threshold16.25460.965319No