The role of the microbiome in weight loss

Many diets are successful in the short run, but following a successful weight loss, up to 80% of all successful dieters tend to re-develop weight gain, a process named relapsing obesity or yoyo obesity. We’ve previously discovered that this exaggerated weight regain tendency is mediated by gut microbe “memory” of past obesity, that predisposes to yoyo obesity following a successful diet. In this study, our team of clinicians, researchers and dietitians will follow participants suffering of obesity in a carefully managed dietary plan, and will test innovative methods of ‘resetting’ the gut microbes as means of preventing yoyo obesity.