Synthetically designed optical biosensors have become the “felt highlighter markers” of science, because they enable one to tag molecules of interest with striking contrast. In this manner, one can determine in colorful relief their location and levels in cells and tissues.
Our lab is working on developing artificial “multicolor” MRI-based sensors that have unlimited tissue penetration with the aim to obtain multiplexed maps of biological phenomena from the deep tissue of live, intact subjects in longitudinal studies.