The Shulman Lab

Antibody-Mediated Immune Responses
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                  Research

                  The origins and functions of antibodies

                  Our research group delves into the fundamental molecular and cellular processes underlying the development of protective antibodies and the establishment of enduring immunity. Employing a combination of mouse models and human-derived tissues, along with advanced imaging techniques and next-generation genomics, we unveil the regulatory mechanisms governing antibody-mediated immunity in the context of vaccination, pathogen invasion, and cancer.

                  Research page

                  Selected Publications

                  Repertoires and Tumor-Reactivity Analysis of B Cell Immunoglobulins Derived from Cancer Patients

                  Stoler-Barak L., Sarusi-Portuguez A. & Shulman Z. (2025) Methods in molecular biology (Clifton, N.J.). 2864, p. 263-279

                  SMARCA5-mediated chromatin remodeling is required for germinal center formation

                  Stoler-Barak L., Schmiedel D., Sarusi-Portuguez A., Rogel A., Blecher-Gonen R., Haimon Z., Stopka T. & Shulman Z. (2024) Journal of Experimental Medicine. 221, 11, e20240433.

                  Turbinate-homing IgA-secreting cells originate in the nasal lymphoid tissues

                  Liu J., Stoler-Barak L., Hezroni-Bravyi H., Biram A., Lebon S., Davidzohn N., Kedmi M., Chemla M., Pilzer D., Cohen M., Brenner O., Biton M. & Shulman Z. (2024) Nature. 632, 8025, p. 637-646
                  All Publications