Professor Zelig Eshhar The Marshall and Renette Ezralow Professor of Chemical and Cellular Immunology E-mail: zelig.eshhar@weizmann.ac.il Phone: +972-8-934-3965 Fax: +972-8-947-4030 Location: Wolfson Bldg., Room 426

 List of Publications (last 3 years):

• Papo, N., Seger, D., Makovitzki, A., Kalchenko, V., Eshhar, Z., Degani, H., and Yaari, S. 2006. "Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of host defense-like lytic peptide." Cancer Research, 66:5371-8.

• Kershaw M.H.,Westwood J.A., Parker L.L.,Wang G., Eshhar Z., et al. (2006)." A phase I trial utilizing adoptive transfer of gene-modified T cell for ovarian cancer." Clin. Can. Res., 12: 6106-6115.

• Morvinski-Friedman D, A. and Eshhar, Z. (2006) "Adoptive Immunotherapy of Cancer Using Effector Lymphocytes Redirected with Antibody Specificity.� CCBRM - Vol. 23, from Elsevier.

• Eshhar, Z. (2007) "The T-body approach: redirecting T cells with antibody specificity." Hand book Exp Pharmacol., 2008;(181):329-42. Review.

• Agemy L., Harmelin A., Waks T., Leibovitch I., Rabin T., Pfeffer RM., and Eshhar Z. (2008) "Irradiation Enhances the Metastatic Potential of Prostatic Small Cell Carcinoma Xenografts." Prostate, 68:530-9.

• Eran Elinav, Tova Waks, Zelig Eshhar (2009). "Redirection of regulatory T cells with antibody specificity for treatment of colitis." Gastroenterology, 134:2014-24.

• Itai Kela, Alon Harmelin, Tova Waks, Avi Orr-Urtreger, Eytan Domany and Zelig Eshhar (2009). "Interspecies Comparison of Prostate Cancer Gene-Expression Profiles Reveals Tumor Aggressive Associated Genes." Prostate, 69:1034-44.

• Dinorah Friedmann-Morvinski and Zelig Eshhar (2009). "Adoptive transfer of T-bodies: towards and effective cancer immunotherapy." In: Targeted Cancer Immune Therapy, Ed. Li Yan and Joseph Lustgarten, Research Signpost, Springer-Verlag New York. In Press.

• Eran Elinav, Adam Nitzan, Tova Waks and Zelig Eshhar (2009). "Amelioration of colitis by genetically engineered murine regulatory T cells redirected by antigen-specific chimeric receptor." Gastroenterology, 136:1721-31.

• Agemy L., Kela, I., Waks T., Shira A., Orr A., Domany E., and Eshhar Z. "Predisposition of prostate cancer to radiotherapy: Gene expression analysis." Submitted 2009.