Chromosome Catastrophes in Cancer

Human evolution and disease

Our studies proceed along three major lines: (1) Microbial population dynamics under stress, (2) Understanding drought resistance and engineering drought-resistant nutritious plants (3) The plant microbiome and its dynamics

We study the structure, function and evolution of systems that regulate gene expression, with emphasis on translation

Biological circuits: design, function and evolution • Regulatory genome: transcription, replication and the chromatin as a communication platform • Developmental patterning: morphogen gradients, scaling, robustness