The goal of our research is to understand how pancreatic beta cells perform their unique functions

We study the tumor microenvironment, and how it is transcriptionally rewired by stress to promote cancer

We investigate fundamental principles of mutagenesis and gene expression by high-throughput methods

Biological circuits: design, function and evolution • Regulatory genome: transcription, replication and the chromatin as a communication platform • Developmental patterning: morphogen gradients, scaling, robustness