Prof. Eran Hornstein

The Hornstein lab investigates the molecular mechanisms underlying neurodegeneration.

We use multidisciplinary approaches including data science, machine learning, computer vision, single cell RNA-seq, Perturb-seq and iPS cell-derived human neurons. Our team is comprised of both computational scientists and molecular neurobiologists, which collaborate to bring the best of both worlds to our research.

We are particularly interested in alterations in human disease genetics, organellar and RNA biology, biomarker discovery and the connection between biomolecular condensates and neurodegeneration. We specifically focus on amyotrophic lateral sclerosis (ALS) in order to increase our understanding of its molecular pathogenesis and to delineate general concepts of cell biology, which are relevant to the disease.

 We also seek to translate the molecular mechanisms we have discovered into potential therapies. Whether you are more computer science oriented or prefer wet-lab biology, we would be glad to have you join our team for your M.Sc. rotation!