| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YBL111C | YBL111C | SGDID:S000002151 | TIF1 TIF41A YKR059W; TIF2 TIF41B YJL138C J0660 |
ATP-dependent RNA helicase eIF4A (EC 3.6.4.13) (Eukaryotic initiation factor 4A) (eIF-4A) (Stimulator factor I 37 kDa component) (Translation initiation factor 1/2) (p37) |
3.6.4.13 | Saccharomyces cerevisiae | 1fuu_b | P10081 | 97.90 | 2.60E-09 | 3.10E-13 | 101.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YBL111C | YBL111C | SGDID:S000002151 | ST2459 STK_24590 |
ST2459 STK_24590 |
3.6.4.13 | Sulfurisphaera tokodaii | 2z0m_a | Q96XQ7 | 97.80 | 7.60E-09 | 9.70E-13 | 93.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YBL111C | YBL111C | SGDID:S000002151 | POLG |
Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small envelope protein M (Matrix protein); Envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Serine protease subunit NS2B (Flavivirin protease NS2B regulatory subunit) (Non-structural protein 2B); Serine protease NS3 (EC 3.4.21.91) (EC 3.6.1.15) (EC 3.6.4.13) (Flavivirin protease NS3 catalytic subunit) (Non-structural protein 3); Non-structural protein 4A (NS4A); Peptide 2k; Non-structural protein 4B (NS4B); RNA-directed RNA polymerase NS5 (EC 2.1.1.56) (EC 2.1.1.57) (EC 2.7.7.48) (Non-structural protein 5)] |
2.1.1.56,2.1.1.57,2.7.7.48,3.4.21.91,3.6.1.15,3.6.4.13, | Japanese encephalitis | 2z83_a | P27395 | 97.80 | 8.50E-09 | 9.50E-13 | 104.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YBL111C | YBL111C | SGDID:S000002151 | BmVLG |
BmVLG |
3.6.4.13 | Bombyx mori | 4d25_a | O01378 | 97.90 | 2.70E-09 | 3.20E-13 | 103.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YBL111C | YBL111C | SGDID:S000002151 | HAS1 YMR290C |
ATP-dependent RNA helicase HAS1 (EC 3.6.4.13) (Helicase associated with SET1 protein 1) |
3.6.4.13 | Saccharomyces cerevisiae | 5z3g_y | Q03532 | 98.10 | 1.10E-09 | 1.30E-13 | 111.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YBL111C | YBL111C | SGDID:S000002151 | PRP28 YDR243C YD8419.10C |
Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (EC 3.6.4.13) (Helicase CA8) |
3.6.4.13 | Saccharomyces cerevisiae | 4w7s_a | P23394 | 98.10 | 8.50E-10 | 1.00E-13 | 108.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YBL111C | YBL111C | SGDID:S000002151 | cshA GT50_10605 |
cshA GT50_10605 |
Geobacillus stearothermophilus | 5ivl_b | A0A0K2H973 | 98.00 | 2.10E-09 | 2.50E-13 | 104.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YBL111C | YBL111C | SGDID:S000002151 | EIF4A1 DDX2A EIF4A |
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1) |
3.6.4.13 | Homo sapiens | Ovary Sarcoma |
5zc9_a | P60842 | ENSG00000161960 | EIF4A1 | 98.00 | 1.80E-09 | 2.20E-13 | 101.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YBL111C | YBL111C | SGDID:S000002151 | DBP5 RAT8 YOR046C |
ATP-dependent RNA helicase DBP5 (EC 3.6.4.13) (DEAD box protein 5) (Helicase CA5/6) (Ribonucleic acid-trafficking protein 8) |
3.6.4.13 | Saccharomyces cerevisiae | 3pey_a | P20449 | 98.00 | 1.30E-09 | 1.70E-13 | 102.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YBL111C | YBL111C | SGDID:S000002151 | DDX19B DBP5 DDX19 TDBP |
ATP-dependent RNA helicase DDX19B (EC 3.6.4.13) (DEAD box RNA helicase DEAD5) (DEAD box protein 19B) |
3.6.4.13 | Homo sapiens | Anterior Horn Cell Disease,Lethal Congenital Contracture Syndrome 1,Lethal Congenital Contracture Syndrome |
6b4j_e | Q9UMR2 | ENSG00000157349 | DDX19B | 97.90 | 5.10E-09 | 6.10E-13 | 101.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YBL111C | YBL111C | SGDID:S000002151 | DHH1 YDL160C |
ATP-dependent RNA helicase DHH1 (EC 3.6.4.13) (DExD/H-box helicase 1) |
3.6.4.13 | Saccharomyces cerevisiae | 1s2m_a | P39517 | 97.90 | 3.00E-09 | 3.70E-13 | 101.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YBL111C | YBL111C | SGDID:S000002151 | secA azi pea prlD b0098 JW0096 |
Protein translocase subunit SecA |
Escherichia coli | 3bxz_b | P10408 | 97.80 | 7.40E-09 | 8.60E-13 | 103.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | ||||
| YBL111C | YBL111C | SGDID:S000002151 | DDX23 |
Probable ATP-dependent RNA helicase DDX23 (EC 3.6.4.13) (100 kDa U5 snRNP-specific protein) (DEAD box protein 23) (PRP28 homolog) (U5-100kD) |
3.6.4.13 | Homo sapiens | Retinitis Pigmentosa,Burn-Mckeown Syndrome,Distal Hereditary Motor Neuronopathy Type 2,Cockayne Syndrome,Spinal Muscular Atrophy, Type I |
4nho_a | Q9BUQ8 | ENSG00000174243 | DDX23 | 97.90 | 3.60E-09 | 4.30E-13 | 104.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YBL111C | YBL111C | SGDID:S000002151 | SKI2 YLR398C L8084.17 |
Antiviral helicase SKI2 (EC 3.6.4.13) (Superkiller protein 2) |
3.6.4.13 | Saccharomyces cerevisiae | 4buj_a | P35207 | 97.80 | 1.10E-08 | 1.10E-12 | 116.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YBL111C | YBL111C | SGDID:S000002151 | RECQL5 RECQ5 |
ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5) |
3.6.4.12 | Homo sapiens | Rothmund-Thomson Syndrome, Type 2,Baller-Gerold Syndrome,Werner Syndrome,Fanconi Anemia, Complementation Group A,Bloom Syndrome,Rapadilino Syndrome |
5lb3_e | O94762 | ENSG00000108469 | RECQL5 | 98.00 | 2.60E-09 | 3.10E-13 | 104.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YBL111C | YBL111C | SGDID:S000002151 | SUB2 YDL084W |
ATP-dependent RNA helicase SUB2 (EC 3.6.4.13) (Suppressor of BRR1 protein 2) |
3.6.4.13 | Saccharomyces cerevisiae | 5sup_b | Q07478 | 98.10 | 5.80E-10 | 7.20E-14 | 105.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YBL111C | YBL111C | SGDID:S000002151 | DDX6 HLR2 RCK |
Probable ATP-dependent RNA helicase DDX6 (EC 3.6.4.13) (ATP-dependent RNA helicase p54) (DEAD box protein 6) (Oncogene RCK) |
3.6.4.13 | Homo sapiens | Nodal Marginal Zone Lymphoma,Non-Specific Syndromic Intellectual Disability,Noonan Syndrome 3,Telecanthus,Intellectual Developmental Disorder With Impaired Language And Dysmorphic Facies |
4ct4_b | P26196 | ENSG00000110367 | DDX6 | 97.90 | 3.80E-09 | 4.80E-13 | 98.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YBL111C | YBL111C | SGDID:S000002151 | RNA helicase (EC 3.6.4.13) |
RNA helicase (EC 3.6.4.13) |
3.6.4.13 | Gallus gallus | 5jaj_a | G0YYQ5 | 97.90 | 5.40E-09 | 6.10E-13 | 110.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YBL111C | YBL111C | SGDID:S000002151 | secA2 Rv1821 MTCY1A11.22c |
Protein translocase subunit SecA 2 |
Mycobacterium tuberculosis | 4uaq_a | P9WGP3 | 97.80 | 9.30E-09 | 9.90E-13 | 112.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YBL111C | YBL111C | SGDID:S000002151 | PRP5 RNA5 YBR237W YBR1603 |
Pre-mRNA-processing ATP-dependent RNA helicase PRP5 (EC 3.6.4.13) |
3.6.4.13 | Saccharomyces cerevisiae | 4ljy_a | P21372 | 98.10 | 9.90E-10 | 1.20E-13 | 109.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YBL111C | YBL111C | SGDID:S000002151 | secA TM_1578 |
Protein translocase subunit SecA |
Thermotoga maritima | 3jux_a | Q9X1R4 | 97.90 | 6.00E-09 | 6.10E-13 | 116.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YBL111C | YBL111C | SGDID:S000002151 | RECQL RECQ1 RECQL1 |
ATP-dependent DNA helicase Q1 (EC 3.6.4.12) (DNA helicase, RecQ-like type 1) (RecQ1) (DNA-dependent ATPase Q1) (RecQ protein-like 1) |
3.6.4.12 | Homo sapiens | Rothmund-Thomson Syndrome, Type 2,Baller-Gerold Syndrome,Inherited Cancer-Predisposing Syndrome,Ovarian Cancer,Hereditary Breast Ovarian Cancer Syndrome,Werner Syndrome,Xeroderma Pigmentosum, Complementation Group C,Xeroderma Pigmentosum, Variant Type,Fanconi Anemia, Complementation Group A,Tumor Predisposition Syndrome,Cutaneous Telangiectasia And Cancer Syndrome, Familial,Bloom Syndrome,Rapadilino Syndrome |
2v1x_b | P46063 | ENSG00000004700 | RECQL | 97.80 | 6.60E-09 | 6.90E-13 | 110.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YBL111C | YBL111C | SGDID:S000002151 | MSS116 YDR194C YD9346.05C |
ATP-dependent RNA helicase MSS116, mitochondrial (EC 3.6.4.13) |
3.6.4.13 | Saccharomyces cerevisiae | 3i5x_a | P15424 | 98.00 | 2.50E-09 | 2.80E-13 | 110.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YBL111C | YBL111C | SGDID:S000002151 | DR_1289 |
DR_1289 |
3.6.4.12 | Deinococcus radiodurans | 4q47_a | Q9RUU2 | 97.90 | 4.90E-09 | 5.40E-13 | 107.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YBL111C | YBL111C | SGDID:S000002151 | EIF4A3 DDX48 KIAA0111 |
Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed] |
3.6.4.13 | Homo sapiens | Metaphyseal Chondrodysplasia, Schmid Type,Robin Sequence With Cleft Mandible And Limb Anomalies,Dysostosis,Vaginal Cancer,Neurodegeneration With Brain Iron Accumulation,Thrombocytopenia-Absent Radius Syndrome,Mandibulofacial Dysostosis, Guion-Almeida Type,Acrofacial Dysostosis |
6qdv_7 | P38919 | ENSG00000141543 | EIF4A3 | 98.00 | 1.30E-09 | 1.70E-13 | 102.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |