Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
YBR114W | RAD16 | SGDID:S000000318 | MDA5 |
MDA5 |
3.6.4.13 | Gallus gallus | 5jcf_b | D9N195 | 99.20 | 2.30E-15 | 1.90E-19 | 176.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | DDX6 HLR2 RCK |
Probable ATP-dependent RNA helicase DDX6 (EC 3.6.4.13) (ATP-dependent RNA helicase p54) (DEAD box protein 6) (Oncogene RCK) |
3.6.4.13 | Homo sapiens | Nodal Marginal Zone Lymphoma,Non-Specific Syndromic Intellectual Disability,Noonan Syndrome 3,Telecanthus,Intellectual Developmental Disorder With Impaired Language And Dysmorphic Facies |
4ct4_b | P26196 | ENSG00000110367 | DDX6 | 99.20 | 1.90E-15 | 1.70E-19 | 159.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YBR114W | RAD16 | SGDID:S000000318 | DNA repair and recombination protein RAD54-like (EC 3.6.4.12) |
Danio rerio | 1z3i_x | Q7ZV09 | 99.70 | 1.10E-21 | 9.60E-26 | 228.10 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | |||||
YBR114W | RAD16 | SGDID:S000000318 | AF_0358 |
AF_0358 |
3.6.4.12 | Archaeoglobus fulgidus | 2fwr_a | O29889 | 99.20 | 4.10E-15 | 3.40E-19 | 165.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | RECQL RECQ1 RECQL1 |
ATP-dependent DNA helicase Q1 (EC 3.6.4.12) (DNA helicase, RecQ-like type 1) (RecQ1) (DNA-dependent ATPase Q1) (RecQ protein-like 1) |
3.6.4.12 | Homo sapiens | Rothmund-Thomson Syndrome, Type 2,Baller-Gerold Syndrome,Inherited Cancer-Predisposing Syndrome,Ovarian Cancer,Hereditary Breast Ovarian Cancer Syndrome,Werner Syndrome,Xeroderma Pigmentosum, Complementation Group C,Xeroderma Pigmentosum, Variant Type,Fanconi Anemia, Complementation Group A,Tumor Predisposition Syndrome,Cutaneous Telangiectasia And Cancer Syndrome, Familial,Bloom Syndrome,Rapadilino Syndrome |
2v1x_b | P46063 | ENSG00000004700 | RECQL | 99.20 | 2.70E-15 | 2.20E-19 | 172.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YBR114W | RAD16 | SGDID:S000000318 | DR_1289 |
DR_1289 |
3.6.4.12 | Deinococcus radiodurans | 4q47_a | Q9RUU2 | 99.20 | 1.60E-15 | 1.30E-19 | 171.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | rapA ECS88_0062 |
RNA polymerase-associated protein RapA (EC 3.6.4.-) (ATP-dependent helicase HepA) |
3.6.4.- | Escherichia coli | 6bog_b | B7MAI2 | 99.40 | 4.80E-17 | 3.80E-21 | 197.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
YBR114W | RAD16 | SGDID:S000000318 | SNF2 GAM1 RIC1 SWI2 TYE3 YOR290C |
Transcription regulatory protein SNF2 (EC 3.6.4.-) (ATP-dependent helicase SNF2) (Regulatory protein GAM1) (Regulatory protein SWI2) (SWI/SNF complex component SNF2) (Transcription factor TYE3) |
3.6.4.- | Saccharomyces cerevisiae | 6iy2_o | P22082 | 99.70 | 1.60E-21 | 1.30E-25 | 229.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | MJ0669 |
Probable ATP-dependent RNA helicase MJ0669 (EC 3.6.4.13) |
3.6.4.13 | Methanocaldococcus jannaschii | 1hv8_a | Q58083 | 99.10 | 6.20E-15 | 5.50E-19 | 154.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | DDX3X DBX DDX3 |
ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (CAP-Rf) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (DBX) (Helicase-like protein 2) (HLP2) |
3.6.4.13 | Homo sapiens | Hepatitis C,Hepatitis B,Venezuelan Equine Encephalitis,Encephalitis,Corpus Callosum, Agenesis Of, With Facial Anomalies And Robin Sequence,Lymphocytic Choriomeningitis,Rare Genetic Intellectual Disability,Hepatitis,Infratentorial Cancer,Ddx3x-Related Neurodevelopmental Disorder,Basal Cell Nevus Syndrome,Precursor T-Cell Acute Lymphoblastic Leukemia,Breast Cancer,Microcephaly,Hepatitis C Virus,Alacrima, Achalasia, And Mental Retardation Syndrome,Noonan Syndrome 3,Disease Of Mental Health,Adult Medulloblastoma,Childhood Medulloblastoma,Intellectual Developmental Disorder, X-Linked, Syndromic, Snijders Blok Type,Ewing Sarcoma,Syndromic Intellectual Disability,Agenesis Of Corpus Callosum, Cardiac, Ocular, And Genital Syndrome,Medulloblastoma,Systemic Epstein-Barr Virus-Positive T-Cell Lymphoma Of Childhood,Cerebellar Hypoplasia/Atrophy, Epilepsy, And Global Developmental Delay |
2i4i_a | O00571 | ENSG00000215301 | DDX3X | 99.20 | 2.20E-15 | 2.00E-19 | 161.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YBR114W | RAD16 | SGDID:S000000318 | DHH1 YDL160C |
ATP-dependent RNA helicase DHH1 (EC 3.6.4.13) (DExD/H-box helicase 1) |
3.6.4.13 | Saccharomyces cerevisiae | 1s2m_a | P39517 | 99.10 | 5.70E-15 | 4.90E-19 | 158.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | SSO1653 |
SSO1653 |
Saccharolobus solfataricus | 1z63_b | Q97XQ7 | 99.60 | 1.80E-19 | 1.50E-23 | 202.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YBR114W | RAD16 | SGDID:S000000318 | TIF1 TIF41A YKR059W; TIF2 TIF41B YJL138C J0660 |
ATP-dependent RNA helicase eIF4A (EC 3.6.4.13) (Eukaryotic initiation factor 4A) (eIF-4A) (Stimulator factor I 37 kDa component) (Translation initiation factor 1/2) (p37) |
3.6.4.13 | Saccharomyces cerevisiae | 1fuk_a | P10081 | 99.10 | 8.10E-15 | 6.30E-19 | 139.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | ERCC3 XPB XPBC |
General transcription and DNA repair factor IIH helicase subunit XPB (TFIIH subunit XPB) (EC 3.6.4.12) (Basic transcription factor 2 89 kDa subunit) (BTF2 p89) (DNA excision repair protein ERCC-3) (DNA repair protein complementing XP-B cells) (TFIIH basal transcription factor complex 89 kDa subunit) (TFIIH 89 kDa subunit) (TFIIH p89) (Xeroderma pigmentosum group B-complementing protein) |
3.6.4.12 | Homo sapiens | Cerebro-Oculo-Facio-Skeletal Syndrome,Ichthyosis,Retinitis Pigmentosa,Hair Disease,Robinow Syndrome, Autosomal Recessive 1,Cockayne Syndrome A,Xeroderma Pigmentosum-Cockayne Syndrome Complex,Xeroderma Pigmentosum Group E,Trichothiodystrophy 1, Photosensitive,Cockayne Syndrome,Trichothiodystrophy,Breast Cancer,Xeroderma Pigmentosum, Complementation Group C,Xeroderma Pigmentosum, Complementation Group D,Xeroderma Pigmentosum, Variant Type,Xeroderma Pigmentosum, Complementation Group F,Xeroderma Pigmentosum, Complementation Group G,Skin Carcinoma,Xeroderma Pigmentosum, Complementation Group B,Xfe Progeroid Syndrome,Autosomal Recessive Disease,Trichothiodystrophy 2, Photosensitive,Trichothiodystrophy 3, Photosensitive,Ifap Syndrome 1, With Or Without Bresheck Syndrome,Uv-Sensitive Syndrome |
5of4_a | P19447 | ENSG00000163161 | ERCC3 | 99.10 | 9.70E-15 | 7.80E-19 | 166.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YBR114W | RAD16 | SGDID:S000000318 | SWR1 YDR334W D9651.6 |
Helicase SWR1 (EC 3.6.4.12) (Swi2/Snf2-related 1) |
3.6.4.12 | Saccharomyces cerevisiae | 6gej_m | Q05471 | 99.70 | 3.30E-23 | 2.50E-27 | 259.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | MYCTH_115909 |
MYCTH_115909 |
Myceliophthora thermophila | 5hzr_a | G2QDW1 | 99.60 | 6.00E-21 | 4.90E-25 | 226.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YBR114W | RAD16 | SGDID:S000000318 | SKI2 YLR398C L8084.17 |
Antiviral helicase SKI2 (EC 3.6.4.13) (Superkiller protein 2) |
3.6.4.13 | Saccharomyces cerevisiae | 4buj_a | P35207 | 99.30 | 1.40E-16 | 1.10E-20 | 195.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | PF2015 |
PF2015 |
Pyrococcus furiosus | 1wp9_a | Q8TZH8 | 99.20 | 1.70E-15 | 1.50E-19 | 164.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YBR114W | RAD16 | SGDID:S000000318 | recQ b3822 JW5855 |
ATP-dependent DNA helicase RecQ (EC 3.6.4.12) |
3.6.4.12 | Escherichia coli | 1oyw_a | P15043 | 99.10 | 7.30E-15 | 6.10E-19 | 165.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
YBR114W | RAD16 | SGDID:S000000318 | SSL2 LOM3 RAD25 UVS112 YIL143C |
General transcription and DNA repair factor IIH helicase subunit XPB (TFIIH subunit XPB) (EC 3.6.4.12) (DNA repair helicase RAD25) (RNA polymerase II transcription factor B subunit SSL2) (TFB subunit SSL2) (Suppressor of stem-loop mutation 2) |
3.6.4.12 | Saccharomyces cerevisiae | 5fmf_1 | Q00578 | 99.10 | 6.30E-15 | 5.30E-19 | 164.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | CTHT_0026210 |
CTHT_0026210 |
Chaetomium thermophilum | 6g7e_b | G0S6C0 | 99.60 | 5.90E-20 | 4.90E-24 | 238.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YBR114W | RAD16 | SGDID:S000000318 | secA div+ BSU35300 |
Protein translocase subunit SecA |
Bacillus subtilis | 2ibm_a | P28366 | 99.20 | 2.30E-15 | 1.90E-19 | 178.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YBR114W | RAD16 | SGDID:S000000318 | B9B11.040 frh NCU03363.1 |
B9B11.040 frh NCU03363.1 |
Neurospora crassa | 4xgt_a | Q873J5 | 99.10 | 1.10E-14 | 9.20E-19 | 177.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YBR114W | RAD16 | SGDID:S000000318 | vas vasa CG46283 |
ATP-dependent RNA helicase vasa (EC 3.6.4.13) (Antigen Mab46F11) |
3.6.4.13 | Drosophila melanogaster | 2db3_b | P09052 | 99.10 | 4.40E-15 | 3.80E-19 | 161.50 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | MTR4 DOB1 YJL050W J1158 |
ATP-dependent RNA helicase DOB1 (EC 3.6.4.13) (mRNA transport regulator MTR4) |
3.6.4.13 | Saccharomyces cerevisiae | 4u4c_a | P47047 | 99.20 | 8.20E-16 | 6.70E-20 | 187.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | RIG-I |
RIG-I |
3.6.4.13 | Anas platyrhynchos | 4a36_a | D3TI84 | 99.20 | 8.30E-16 | 7.10E-20 | 173.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | PRP28 YDR243C YD8419.10C |
Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (EC 3.6.4.13) (Helicase CA8) |
3.6.4.13 | Saccharomyces cerevisiae | 4w7s_a | P23394 | 99.10 | 7.30E-15 | 6.30E-19 | 161.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | Ddx58 |
Antiviral innate immune response receptor RIG-I (DEAD box protein 58) (Probable ATP-dependent RNA helicase DDX58) (EC 3.6.4.13) (RIG-I-like receptor 1) (RLR-1) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I) |
3.6.4.13 | Mus musculus | 3tbk_a | Q6Q899 | 99.40 | 1.80E-17 | 1.60E-21 | 187.20 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | BmVLG |
BmVLG |
3.6.4.13 | Bombyx mori | 4d25_a | O01378 | 99.10 | 7.30E-15 | 6.30E-19 | 159.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | RAD26 GTA1085 YJR035W J1606 |
DNA repair and recombination protein RAD26 (EC 3.6.4.12) (ATP-dependent helicase RAD26) |
3.6.4.12 | Saccharomyces cerevisiae | 5vvr_m | P40352 | 99.70 | 2.50E-22 | 1.90E-26 | 246.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | DDX23 |
Probable ATP-dependent RNA helicase DDX23 (EC 3.6.4.13) (100 kDa U5 snRNP-specific protein) (DEAD box protein 23) (PRP28 homolog) (U5-100kD) |
3.6.4.13 | Homo sapiens | Retinitis Pigmentosa,Burn-Mckeown Syndrome,Distal Hereditary Motor Neuronopathy Type 2,Cockayne Syndrome,Spinal Muscular Atrophy, Type I |
4nho_a | Q9BUQ8 | ENSG00000174243 | DDX23 | 99.20 | 1.10E-15 | 9.30E-20 | 169.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YBR114W | RAD16 | SGDID:S000000318 | cshA GT50_10605 |
cshA GT50_10605 |
Geobacillus stearothermophilus | 5ivl_b | A0A0K2H973 | 99.20 | 1.80E-15 | 1.60E-19 | 164.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YBR114W | RAD16 | SGDID:S000000318 | PRP5 RNA5 YBR237W YBR1603 |
Pre-mRNA-processing ATP-dependent RNA helicase PRP5 (EC 3.6.4.13) |
3.6.4.13 | Saccharomyces cerevisiae | 4ljy_a | P21372 | 99.20 | 8.30E-16 | 7.10E-20 | 170.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | SUB2 YDL084W |
ATP-dependent RNA helicase SUB2 (EC 3.6.4.13) (Suppressor of BRR1 protein 2) |
3.6.4.13 | Saccharomyces cerevisiae | 5sup_b | Q07478 | 99.20 | 2.20E-15 | 1.90E-19 | 160.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | MYCTH_2307364 |
MYCTH_2307364 |
Myceliophthora thermophila | 5jxr_a | G2QFM3 | 99.70 | 9.60E-22 | 7.60E-26 | 232.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YBR114W | RAD16 | SGDID:S000000318 | EIF4A3 DDX48 KIAA0111 |
Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed] |
3.6.4.13 | Homo sapiens | Metaphyseal Chondrodysplasia, Schmid Type,Robin Sequence With Cleft Mandible And Limb Anomalies,Dysostosis,Vaginal Cancer,Neurodegeneration With Brain Iron Accumulation,Thrombocytopenia-Absent Radius Syndrome,Mandibulofacial Dysostosis, Guion-Almeida Type,Acrofacial Dysostosis |
6qdv_7 | P38919 | ENSG00000141543 | EIF4A3 | 99.10 | 8.70E-15 | 7.60E-19 | 155.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YBR114W | RAD16 | SGDID:S000000318 | xpb2 ST1613 STK_16130 |
xpb2 ST1613 STK_16130 |
Sulfurisphaera tokodaii | 5tnu_a | Q970I2 | 99.20 | 3.90E-15 | 3.30E-19 | 164.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YBR114W | RAD16 | SGDID:S000000318 | MSS116 YDR194C YD9346.05C |
ATP-dependent RNA helicase MSS116, mitochondrial (EC 3.6.4.13) |
3.6.4.13 | Saccharomyces cerevisiae | 3i5x_a | P15424 | 99.10 | 5.30E-15 | 4.50E-19 | 168.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | HAS1 YMR290C |
ATP-dependent RNA helicase HAS1 (EC 3.6.4.13) (Helicase associated with SET1 protein 1) |
3.6.4.13 | Saccharomyces cerevisiae | 5z3g_y | Q03532 | 99.30 | 1.30E-16 | 1.10E-20 | 179.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | RNA helicase (EC 3.6.4.13) |
RNA helicase (EC 3.6.4.13) |
3.6.4.13 | Gallus gallus | 5jaj_a | G0YYQ5 | 99.40 | 2.10E-17 | 1.70E-21 | 193.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | CHD1 YER164W SYGP-ORF4 |
Chromo domain-containing protein 1 (EC 3.6.4.-) (ATP-dependent helicase CHD1) |
3.6.4.- | Saccharomyces cerevisiae | 6ftx_w | P32657 | 99.60 | 3.70E-20 | 3.00E-24 | 223.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | Ifih1 |
Interferon-induced helicase C domain-containing protein 1 (EC 3.6.4.13) (Helicase with 2 CARD domains) (Helicard) (Interferon induced with helicase C domain protein 1) (Melanoma differentiation-associated protein 5) (MDA-5) (RIG-I-like receptor 2) (RLR-2) |
3.6.4.13 | Mus musculus | 6g19_a | Q8R5F7 | 99.30 | 6.10E-16 | 5.10E-20 | 180.90 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | TIF1 TIF41A YKR059W; TIF2 TIF41B YJL138C J0660 |
ATP-dependent RNA helicase eIF4A (EC 3.6.4.13) (Eukaryotic initiation factor 4A) (eIF-4A) (Stimulator factor I 37 kDa component) (Translation initiation factor 1/2) (p37) |
3.6.4.13 | Saccharomyces cerevisiae | 1fuu_b | P10081 | 99.20 | 2.10E-15 | 1.80E-19 | 161.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YBR114W | RAD16 | SGDID:S000000318 | EIF4A1 DDX2A EIF4A |
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1) |
3.6.4.13 | Homo sapiens | Ovary Sarcoma |
5zc9_a | P60842 | ENSG00000161960 | EIF4A1 | 99.20 | 1.80E-15 | 1.50E-19 | 161.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |