| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YCL026C-A | FRM2 | SGDID:S000000589 | SP_0622 |
SP_0622 |
Streptococcus pneumoniae | 2b67_a | A0A0H2UP38 | 99.80 | 1.80E-24 | 1.20E-28 | 149.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | nfsA mda18 mdaA ybjB b0851 JW0835 |
Oxygen-insensitive NADPH nitroreductase (EC 1.-.-.-) (Modulator of drug activity A) |
Escherichia coli | 1f5v_b | P17117 | 99.90 | 1.20E-28 | 7.90E-33 | 175.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | VVA1455 |
VVA1455 |
Vibrio vulnificus | 6czp_b | Q7MCD2 | 99.80 | 2.80E-25 | 1.80E-29 | 155.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | Atu1744 |
Atu1744 |
Agrobacterium fabrum | 3k6h_a | A9CIP6 | 99.80 | 1.20E-25 | 7.70E-30 | 155.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | fbiB Rv3262 |
Bifunctional F420 biosynthesis protein FbiB [Includes: Coenzyme F420:L-glutamate ligase (EC 6.3.2.31) (EC 6.3.2.34) (Coenzyme F420-0:L-glutamate ligase) (Coenzyme F420-1:gamma-L-glutamate ligase); Dehydro-coenzyme F420-0 reductase (EC 1.3.8.-)] |
6.3.2.31,6.3.2.34, | Mycobacterium tuberculosis | 4xom_a | P9WP79 | 99.80 | 4.70E-24 | 3.00E-28 | 148.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YCL026C-A | FRM2 | SGDID:S000000589 | SMU_260 |
SMU_260 |
Streptococcus mutans | 2ifa_b | Q8DW21 | 99.90 | 3.20E-27 | 2.10E-31 | 164.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | rdxA HP_0954 |
Oxygen-insensitive NADPH nitroreductase (EC 1.-.-.-) |
Helicobacter pylori | 3qdl_a | O25608 | 99.80 | 2.60E-25 | 1.70E-29 | 155.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | BF9343_1994 NCTC9343_03654 |
BF9343_1994 NCTC9343_03654 |
Bacteroides fragilis | 3ek3_a | Q5LDN3 | 99.70 | 1.50E-22 | 9.40E-27 | 138.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | nfnB MSMEG_6505 MSMEI_6333 |
Nitroreductase NfnB (NR NfnB) (EC 1.-.-.-) (FMN-dependent NAD(P)H nitroreductase) |
Mycolicibacterium smegmatis | 2wzv_a | A0R6D0 | 99.80 | 3.20E-24 | 2.10E-28 | 151.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | nfrA2 ycnD BSU03860 |
FMN reductase [NAD(P)H] (EC 1.5.1.39) (NAD(P)H-dependent FMN reductase) (NAD(P)H-dependent nitro/flavin reductase) (NAD(P)H-dependent nitroreductase) (NAD(P)H-dependent oxidoreductase) |
1.5.1.39 | Bacillus subtilis | 1zch_a | P94424 | 99.90 | 1.10E-28 | 6.90E-33 | 177.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YCL026C-A | FRM2 | SGDID:S000000589 | BT_0181 |
BT_0181 |
Bacteroides thetaiotaomicron | 3kwk_a | Q8ABC9 | 99.80 | 7.10E-25 | 4.60E-29 | 148.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | CDR20291_0767 |
CDR20291_0767 |
Clostridioides difficile | 5j6c_a | C9YJL7 | 99.80 | 7.80E-25 | 5.00E-29 | 151.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | Gmet_2835 |
Gmet_2835 |
Geobacter metallireducens | 4dn2_a | Q39RS1 | 99.70 | 1.20E-22 | 7.90E-27 | 141.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | cla-er yodC_1 yodC_3 AVR82_03025 AYO51_02570 BIZ32_00255 C7M34_01333 C7M36_01142 DQQ11_00270 E3U93_09060 FET70_02684 IV39_GL000155 Lp19_0957 LPJSA22_00076 LpLQ80_00285 Nizo1839_3020 Nizo2891_2637 |
cla-er yodC_1 yodC_3 AVR82_03025 AYO51_02570 BIZ32_00255 C7M34_01333 C7M36_01142 DQQ11_00270 E3U93_09060 FET70_02684 IV39_GL000155 Lp19_0957 LPJSA22_00076 LpLQ80_00285 Nizo1839_3020 Nizo2891_2637 |
Lactiplantibacillus plantarum | 4qlx_a | U6C5W9 | 99.80 | 4.40E-26 | 2.80E-30 | 160.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | nfrA1 CN918_01900 |
nfrA1 CN918_01900 |
Bacillus megaterium | 5hdj_a | A0A0K0VJM9 | 99.90 | 2.40E-28 | 1.50E-32 | 175.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | nfrA1 nfrA ywcG BSU38110 ipa-43d |
FMN reductase (NADPH) (EC 1.5.1.38) (NADPH-dependent FMN reductase) (NADPH-dependent nitro/flavin reductase) (NADPH-dependent nitroreductase) (NADPH-dependent oxidoreductase) |
1.5.1.38 | Bacillus subtilis | 3n2s_a | P39605 | 99.90 | 4.50E-28 | 2.90E-32 | 173.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YCL026C-A | FRM2 | SGDID:S000000589 | BC_0786 |
BC_0786 |
Bacillus cereus | 2i7h_a | Q81HL8 | 99.90 | 5.50E-27 | 3.50E-31 | 160.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | Dhaf_2018 |
Dhaf_2018 |
Desulfitobacterium hafniense | 3pxv_d | B8FRE0 | 99.80 | 1.90E-24 | 1.20E-28 | 148.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | CD630_33550 |
CD630_33550 |
Clostridioides difficile | 3h4o_a | Q180K0 | 99.70 | 9.10E-23 | 5.80E-27 | 140.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | ytjD L174788 |
ytjD L174788 |
Lactococcus lactis | 2wqf_a | Q9CED0 | 99.90 | 3.50E-28 | 2.30E-32 | 168.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | SE_1966 |
SE_1966 |
Staphylococcus epidermidis | 3gbh_b | A0A0H2VHN8 | 99.80 | 2.80E-26 | 1.80E-30 | 160.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | FRM2 YCL026C-A YCLX08C YCLX8C |
Fatty acid repression mutant protein 2 |
Saccharomyces cerevisiae | 4urp_a | P37261 | 99.90 | 3.20E-29 | 2.10E-33 | 172.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | PG_0310 |
PG_0310 |
Porphyromonas gingivalis | 3ge5_a | Q7MX99 | 99.80 | 6.70E-26 | 4.30E-30 | 156.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | Atu0013 |
Atu0013 |
Agrobacterium fabrum | 2fre_a | A9CKT4 | 99.80 | 1.60E-24 | 1.00E-28 | 149.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | nfsB nfnB nfsI |
Oxygen-insensitive NAD(P)H nitroreductase (NR) (EC 1.-.-.-) |
Enterobacter cloacae | 5j8d_b | Q01234 | 99.80 | 1.60E-25 | 1.00E-29 | 156.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | CT0345 |
CT0345 |
Chlorobaculum tepidum | 2r01_a | Q8KFI1 | 99.80 | 4.70E-25 | 3.00E-29 | 153.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | frp |
NADPH-flavin oxidoreductase (EC 1.5.1.38) (Flavin reductase P) (NADPH-FMN oxidoreductase) |
1.5.1.38 | Vibrio harveyi | 1bkj_a | Q56691 | 100.00 | 8.80E-37 | 5.70E-41 | 216.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YCL026C-A | FRM2 | SGDID:S000000589 | ydjA b1765 JW1754 |
Putative NAD(P)H nitroreductase YdjA (EC 1.-.-.-) |
Escherichia coli | 3bm1_a | P0ACY1 | 99.80 | 1.30E-25 | 8.10E-30 | 153.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | nfnB IL2077 |
nfnB IL2077 |
Idiomarina loihiensis | 3of4_b | Q5R179 | 99.80 | 5.50E-26 | 3.60E-30 | 158.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | BDI_1728 |
BDI_1728 |
Parabacteroides distasonis | 3m5k_a | A6LCR1 | 99.80 | 1.60E-24 | 1.10E-28 | 146.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | mhqN ydfN BSU05480 |
Putative NAD(P)H nitroreductase MhqN (EC 1.-.-.-) |
Bacillus subtilis | 3bem_b | P96692 | 99.80 | 7.00E-26 | 4.50E-30 | 158.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | SMU_346 |
SMU_346 |
Streptococcus mutans | 3gag_a | Q8DVW4 | 99.90 | 2.10E-27 | 1.40E-31 | 165.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | Halhy_2296 |
Halhy_2296 |
Haliscomenobacter hydrossis | 5ko8_b | F4KU78 | 99.80 | 2.10E-25 | 1.40E-29 | 157.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | BF9343_3518 |
BF9343_3518 |
Bacteroides fragilis | 3eof_a | Q5L9C9 | 99.90 | 3.50E-28 | 2.20E-32 | 173.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | noxC NT01CX_1801 |
noxC NT01CX_1801 |
Clostridium novyi | 3g14_b | A0PZS2 | 99.80 | 1.70E-24 | 1.10E-28 | 148.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | FRA1 |
Major NAD(P)H-flavin oxidoreductase (EC 1.6.99.-) (FRASE I) |
1.6.99.- | Aliivibrio fischeri | 1v5y_a | P46072 | 99.80 | 1.70E-25 | 1.10E-29 | 156.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YCL026C-A | FRM2 | SGDID:S000000589 | VPA1601 |
VPA1601 |
Vibrio parahaemolyticus | 5uu6_c | Q87FS7 | 99.90 | 1.00E-28 | 6.50E-33 | 176.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | CDR20291_0684 |
CDR20291_0684 |
Clostridioides difficile | 5j62_a | C9YJD4 | 99.80 | 2.30E-24 | 1.50E-28 | 150.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | CD630_25720 |
CD630_25720 |
Clostridioides difficile | 3eo8_d | Q182R2 | 99.80 | 3.50E-23 | 2.30E-27 | 144.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | Iyd Dehal1 |
Iodotyrosine deiodinase 1 (IYD-1) (EC 1.21.1.1) (Iodotyrosine dehalogenase 1) |
1.21.1.1 | Mus musculus | 3gb5_a | Q9DCX8 | 99.80 | 1.30E-25 | 8.40E-30 | 161.00 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
| YCL026C-A | FRM2 | SGDID:S000000589 | pnbA BH06130 |
pnbA BH06130 |
Bartonella henselae | 3gr3_a | A0A0H3M323 | 99.80 | 6.60E-24 | 4.20E-28 | 149.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | nfsB dprA nfnB nfsI ntr b0578 JW0567 |
Oxygen-insensitive NAD(P)H nitroreductase (EC 1.-.-.-) (Dihydropteridine reductase) (EC 1.5.1.34) (FMN-dependent nitroreductase) |
1.5.1.34 | Escherichia coli | 1icr_a | P38489 | 99.80 | 5.00E-25 | 3.20E-29 | 154.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
| YCL026C-A | FRM2 | SGDID:S000000589 | BC_1844 |
BC_1844 |
Bacillus cereus | 1ywq_a | Q81EW9 | 99.90 | 1.30E-26 | 8.30E-31 | 160.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | Exig_2970 |
Exig_2970 |
Exiguobacterium sibiricum | 3ge6_a | B1YG32 | 99.90 | 6.30E-27 | 4.00E-31 | 163.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | CD630_32050 |
CD630_32050 |
Clostridioides difficile | 3gfa_a | Q17ZU8 | 99.70 | 4.40E-23 | 2.90E-27 | 142.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCL026C-A | FRM2 | SGDID:S000000589 | SPy_0512 |
SPy_0512 |
Streptococcus pyogenes | 2hay_c | Q9A120 | 99.80 | 6.90E-25 | 4.50E-29 | 154.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |