Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
YCL048W | SPS22 | SGDID:S000000553 | IGF1R |
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] |
2.7.10.1 | Homo sapiens | Pancreatic Adenocarcinoma,Bone Disease,Skin Melanoma,Acanthosis Nigricans,Neuroendocrine Tumor,Endometrial Cancer,Autosomal Dominant Polycystic Kidney Disease,Squamous Cell Carcinoma,Hyperglycemia,Lung Cancer Susceptibility 3,Chromosome 15q26-Qter Deletion Syndrome,Rhabdomyosarcoma 2,Polycystic Kidney Disease,Vagina Sarcoma,Melanoma,Thyroid Gland Anaplastic Carcinoma,Diabetes Mellitus,Dedifferentiated Liposarcoma,Hyperinsulinism,Clear Cell Renal Cell Carcinoma,Odontogenic Myxoma,Atypical Teratoid Rhabdoid Tumor,Amelogenesis Imperfecta,Short Syndrome,Graves' Disease,Insulin-Like Growth Factor I,Craniosynostosis,Neuroblastoma,Ring Chromosome 15,Vaginal Endometrial Stromal Sarcoma,Hyperinsulinemic Hypoglycemia,Ring Chromosome,Osteoporosis,Nk-Cell Enteropathy,Ovarian Cancer,Adenocarcinoma,Breast Cancer,Glioblastoma,Colorectal Cancer,Hepatocellular Carcinoma,Malignant Peripheral Nerve Sheath Tumor,Rhabdomyosarcoma,Prostate Embryonal Rhabdomyosarcoma,Myxoid Liposarcoma,Ovarian Disease,Localized Osteosarcoma,Liposarcoma,Skin Carcinoma,Gastric Cancer,Prostate Cancer,Disease Of Mental Health,Rhabdoid Cancer,Adrenal Cortical Carcinoma,Type 2 Diabetes Mellitus,Silver-Russell Syndrome 1,Lung Squamous Cell Carcinoma,Adrenal Cortex Disease,Skeletal Muscle Cancer,Muscle Cancer,Beckwith-Wiedemann Syndrome,Sarcoma, Synovial,Esophageal Cancer,Askin'S Tumor,Hypotrichosis 10,Ewing Sarcoma,Lymphangioleiomyomatosis,Donohue Syndrome,Paraganglioma And Gastric Stromal Sarcoma,Renal Cell Carcinoma, Nonpapillary,Wilms Tumor 1,Nijmegen Breakage Syndrome,Amelogenesis Imperfecta, Type Ig,Medulloblastoma,Melanoma, Uveal,Lung Cancer,Osteogenic Sarcoma,Pancreatic Cancer,Polycythemia Vera |
1igr_a | P08069 | ENSG00000140443 | IGF1R | 97.70 | 2.20E-08 | 2.40E-12 | 96.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YCL048W | SPS22 | SGDID:S000000553 | Recep_L_domain |
Receptor L domain |
pfam Repeat | PF01030 | 97.20 | 3.50E-07 | 4.30E-11 | 68.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||||
YCL048W | SPS22 | SGDID:S000000553 | ERBB3 HER3 |
Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3) |
2.7.10.1 | Homo sapiens | Pancreatic Adenocarcinoma,Uterine Carcinosarcoma,Lung Cancer Susceptibility 3,Clear Cell Sarcoma,Mucinous Lung Adenocarcinoma,Neurogenic Bladder,Acute Erythroid Leukemia,Leukemia,Colonic Benign Neoplasm,Pilocytic Astrocytoma,Acoustic Neuroma,Periampullary Adenocarcinoma,Keratoconjunctivitis Sicca,Transitional Cell Carcinoma,Bladder Cancer,Retroperitoneal Leiomyosarcoma,Paronychia,Mixed Cell Adenoma,Vallecula Cancer,Ovarian Cancer,Gastric Fundus Cancer,Adenocarcinoma,Charcot-Marie-Tooth Disease,Breast Cancer,Glioblastoma,Squamous Cell Carcinoma, Head And Neck,Colorectal Cancer,Squamous Blepharitis,Gallbladder Cancer,Tooth Disease,Gastric Cancer,Breast Adenocarcinoma,Prostate Cancer,Cervical Cancer,Gastric Adenocarcinoma,Verrucous Carcinoma,Childhood Medulloblastoma,Schizophrenia,Ovary Transitional Cell Carcinoma,Bladder Urothelial Carcinoma,Erythroleukemia, Familial,Esophageal Cancer,Ductal Carcinoma In Situ,Estrogen-Receptor Positive Breast Cancer,Lethal Congenital Contracture Syndrome 2,Lethal Congenital Contracture Syndrome 1,Medulloblastoma,Lethal Congenital Contracture Syndrome,Lung Cancer,Pancreatic Cancer |
3p11_a | P21860 | ENSG00000065361 | ERBB3 | 97.30 | 2.10E-07 | 2.40E-11 | 89.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YCL048W | SPS22 | SGDID:S000000553 | INSR |
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta] |
2.7.10.1 | Homo sapiens | Acanthosis Nigricans,Liver Disease,Heart Disease,Autosomal Dominant Polycystic Kidney Disease,Hyperglycemia,Hypertrichosis,Islet Cell Tumor,Myopathy,Polycystic Ovary Syndrome,Hyperandrogenism,Non-Alcoholic Fatty Liver Disease,Gestational Diabetes,Prediabetes Syndrome,Diabetes Mellitus,Fatty Liver Disease,Hyperinsulinism,Alzheimer Disease,Myotonic Disease,Myotonic Dystrophy 1,Fasting Hypoglycemia,Insulin-Like Growth Factor I,Fetal Macrosomia,Hypoglycemia,Liver Cirrhosis,Migraine With Aura,Insr-Related Severe Syndromic Insulin Resistance,Pigmentation Disease,Type 1 Diabetes Mellitus,Hyperinsulinemic Hypoglycemia,Ovarian Cancer,Adenocarcinoma,Glucose Intolerance,Breast Cancer,Colorectal Cancer,Lipid Metabolism Disorder,Ovarian Disease,Hyperinsulinemic Hypoglycemia, Familial, 5,Hyperinsulinemic Hypoglycemia, Familial, 4,Centronuclear Myopathy,Body Mass Index Quantitative Trait Locus 11,Diabetes Mellitus, Insulin-Resistant, With Acanthosis Nigricans,Type 2 Diabetes Mellitus,Abdominal Obesity-Metabolic Syndrome 1,Congenital Generalized Lipodystrophy,Maturity-Onset Diabetes Of The Young,Donohue Syndrome,Hypertension, Essential,Pineal Hyperplasia, Insulin-Resistant Diabetes Mellitus, And Somatic Abnormalities |
2hr7_a | P06213 | ENSG00000171105 | INSR | 97.40 | 9.40E-08 | 1.10E-11 | 91.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |