| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YCR026C | NPP1 | SGDID:S000000621 | SPOA0121 |
SPOA0121 |
Ruegeria pomeroyi | 4upi_a | Q5LLA5 | 99.60 | 8.60E-21 | 7.00E-25 | 216.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCR026C | NPP1 | SGDID:S000000621 | atsA PA0183 |
Arylsulfatase (AS) (EC 3.1.6.1) (Aryl-sulfate sulphohydrolase) |
3.1.6.1 | Pseudomonas aeruginosa | 1hdh_a | P51691 | 99.60 | 1.30E-20 | 1.10E-24 | 211.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YCR026C | NPP1 | SGDID:S000000621 | phnA SM_b21538 |
phnA SM_b21538 |
3.6.1.9 | Rhizobium meliloti | 3szy_a | Q92UV8 | 99.80 | 8.60E-26 | 7.10E-30 | 247.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YCR026C | NPP1 | SGDID:S000000621 | IDS SIDS |
Iduronate 2-sulfatase (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Cleaved into: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain] |
3.1.6.13 | Homo sapiens | Mucopolysaccharidosis Iii,Mucopolysaccharidosis-Plus Syndrome,Mucopolysaccharidosis Iv,Sudden Infant Death Syndrome,Tay-Sachs Disease,Lysosomal Storage Disease,Refractory Cytopenia With Multilineage Dysplasia,Gm1-Gangliosidosis, Type Ii,Krabbe Disease,Hurler Syndrome,Epidermolysis Bullosa Simplex With Nail Dystrophy,Scheie Syndrome,Metachromatic Leukodystrophy,Mucopolysaccharidosis, Type Ii,Mucopolysaccharidosis, Type Iiia,Mucopolysaccharidosis, Type Iiib,Mucopolysaccharidosis, Type Iiic,Mucopolysaccharidosis, Type Iiid,Mucopolysaccharidosis, Type Iva,Mucopolysaccharidosis, Type Ivb,Mucopolysaccharidosis, Type Vi,Mucopolysaccharidosis, Type Vii |
6ioz_a | P22304 | ENSG00000010404 | IDS | 99.60 | 1.30E-20 | 1.10E-24 | 211.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YCR026C | NPP1 | SGDID:S000000621 | Enpp6 |
Glycerophosphocholine cholinephosphodiesterase ENPP6 (GPC-Cpde) (EC 3.1.4.-) (EC 3.1.4.38) (Choline-specific glycerophosphodiester phosphodiesterase) (Ectonucleotide pyrophosphatase/phosphodiesterase family member 6) (E-NPP 6) (NPP-6) |
3.1.4.38 | Mus musculus | 5egh_a | Q8BGN3 | 99.90 | 9.60E-30 | 7.90E-34 | 280.60 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
| YCR026C | NPP1 | SGDID:S000000621 | Enpp1 Npps Pc1 Pdnp1 |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (E-NPP 1) (Lymphocyte antigen 41) (Ly-41) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Cleaved into: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, secreted form] [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9) (Nucleotide diphosphatase)] |
3.1.4.1,3.6.1.9, | Mus musculus | 4b56_a | P06802 | 100.00 | 8.00E-35 | 6.40E-39 | 348.10 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
| YCR026C | NPP1 | SGDID:S000000621 | ENPP4 KIAA0879 NPP4 |
Bis(5'-adenosyl)-triphosphatase ENPP4 (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Ectonucleotide pyrophosphatase/phosphodiesterase family member 4) (E-NPP 4) (NPP-4) |
3.6.1.29 | Homo sapiens | 4lqy_a | Q9Y6X5 | ENSG00000001561 | ENPP4 | 99.90 | 8.10E-29 | 6.70E-33 | 270.50 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YCR026C | NPP1 | SGDID:S000000621 | ENPP7 UNQ3077/PRO9912 |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (E-NPP 7) (NPP-7) (EC 3.1.4.12) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase) |
3.1.4.12 | Homo sapiens | Colorectal Cancer,Familial Adenomatous Polyposis |
5tcd_a | Q6UWV6 | ENSG00000182156 | ENPP7 | 99.90 | 5.90E-30 | 4.80E-34 | 282.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YCR026C | NPP1 | SGDID:S000000621 | phoK |
Alkaline phosphatase PhoK (EC 3.1.3.1) (SPAP protein) |
3.1.3.1 | Sphingomonas sp. | 5xwi_a | A1YYW7 | 99.80 | 1.10E-25 | 8.70E-30 | 257.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YCR026C | NPP1 | SGDID:S000000621 | Enpp2 Npps2 Pdnp2 |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (E-NPP 2) (EC 3.1.4.39) (Autotaxin) (Extracellular lysophospholipase D) (LysoPLD) |
3.1.4.39 | Mus musculus | 3nkm_a | Q9R1E6 | 99.90 | 4.10E-33 | 3.30E-37 | 333.40 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
| YCR026C | NPP1 | SGDID:S000000621 | SPO3593 |
SPO3593 |
Ruegeria pomeroyi | 4upl_a | Q5LMH0 | 99.60 | 6.40E-21 | 5.20E-25 | 217.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCR026C | NPP1 | SGDID:S000000621 | DC53_12720 |
DC53_12720 |
Pseudoalteromonas fuliginea | 6b0k_c | A0A063KPH1 | 99.60 | 1.80E-20 | 1.50E-24 | 206.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCR026C | NPP1 | SGDID:S000000621 | Enpp5 |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-) |
3.1.-.- | Mus musculus | 5veo_a | Q9EQG7 | 99.90 | 4.30E-30 | 3.50E-34 | 282.70 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
| YCR026C | NPP1 | SGDID:S000000621 | phnA |
Phosphonoacetate hydrolase (EC 3.11.1.2) |
3.11.1.2 | Pseudomonas fluorescens | 1ei6_a | Q51782 | 99.80 | 4.90E-26 | 4.10E-30 | 247.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YCR026C | NPP1 | SGDID:S000000621 | XAC2824 |
XAC2824 |
Xanthomonas axonopodis | 2gso_a | Q8PIS1 | 99.90 | 1.10E-30 | 9.00E-35 | 284.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCR026C | NPP1 | SGDID:S000000621 | ARSA |
Arylsulfatase A (ASA) (EC 3.1.6.8) (Cerebroside-sulfatase) [Cleaved into: Arylsulfatase A component B; Arylsulfatase A component C] |
3.1.6.8 | Homo sapiens | Ichthyosis,Mucolipidosis,Gaucher'S Disease,Sphingolipidosis,Dysostosis,Cerebral Palsy,Lipid Storage Disease,Sandhoff Disease,Kleptomania,Mucopolysaccharidosis Iii,Mucopolysaccharidosis-Plus Syndrome,Mucopolysaccharidosis Iv,Canavan Disease,Multiple Sulfatase Deficiency,Hereditary Dystonia,Dementia,Autosomal Recessive Sideroblastic Anemia,Gingival Hypertrophy,Tay-Sachs Disease,Leukodystrophy,Polyneuropathy,Spinocerebellar Ataxia, Autosomal Recessive 14,Metachromatic Leukodystrophy, Adult Form,Metachromatic Leukodystrophy, Late Infantile Form,Metachromatic Leukodystrophy, Juvenile Form,Lysosomal Storage Disease,Demyelinating Disease,Gm2 Gangliosidosis,Gm1 Gangliosidosis,Sneddon Syndrome,Combined Saposin Deficiency,Autosomal Recessive Disease,Krabbe Disease,Fabry Disease,Scheie Syndrome,Metachromatic Leukodystrophy,Mucolipidosis Iii Alpha/Beta,Ceroid Lipofuscinosis, Neuronal, 3,Mucopolysaccharidosis, Type Ii,Mucopolysaccharidosis, Type Iiia,Mucopolysaccharidosis, Type Iva,Mucopolysaccharidosis, Type Vi,Mucopolysaccharidosis, Type Vii,Niemann-Pick Disease, Type C1 |
1n2l_a | P15289 | ENSG00000100299 | ARSA | 99.70 | 3.30E-21 | 2.70E-25 | 215.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YCR026C | NPP1 | SGDID:S000000621 | BN863_22070 |
Ulvan-active sulfatase (EC 3.1.6.-) (Arylsulfatase) (Polysaccharide utilization locus H protein P18) (PUL H protein P18) (Sulfatase family S1 subfamily 7 protein P18) (P18_S1_7) |
3.1.6.- | Formosa agariphila | 6hhm_a | T2KPK5 | 99.60 | 5.50E-21 | 4.50E-25 | 212.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YCR026C | NPP1 | SGDID:S000000621 | BT_1596 |
Delta 4,5-hexuronate-2-O-sulfatase (EC 3.1.6.-) |
3.1.6.- | Bacteroides thetaiotaomicron | 3b5q_b | Q8A7C8 | 99.60 | 1.90E-20 | 1.60E-24 | 208.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YCR026C | NPP1 | SGDID:S000000621 | ENPP3 PDNP3 |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (E-NPP 3) (NPP3) (Phosphodiesterase I beta) (PD-Ibeta) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (CD antigen CD203c) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9) (Nucleotide diphosphatase)] |
3.1.4.1,3.6.1.9, | Homo sapiens | Egg Allergy,Nut Allergy,Chronic Urticaria,Chronic Inducible Urticaria,Dermatographia,Exercise-Induced Anaphylaxis,Aggressive Systemic Mastocytosis,Allergic Bronchopulmonary Aspergillosis,Food Allergy,Cholinergic Urticaria,Systemic Mastocytosis,Mastocytosis,Urticaria,Wheat Allergy,Cutaneous Solitary Mastocytoma,Amoxicillin Allergy,Cephalosporin Allergy,Chlorhexidine Allergy,Diclofenac Allergy,Carbapenem Allergy,Co-Trimoxazole Allergy,Oxirane Allergy,Scalp-Ear-Nipple Syndrome,Aspergillosis,Hypophosphatasia, Childhood,Arterial Calcification Of Infancy,Physical Urticaria,Respiratory Allergy,Pollen Allergy,Drug Allergy,Fruit Allergy,Apricot Allergy,Peach Allergy,Beta-Lactam Allergy,Crab Allergy,Legume Allergy |
6c01_a | O14638 | ENSG00000154269 | ENPP3 | 100.00 | 9.90E-35 | 7.90E-39 | 348.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YCR026C | NPP1 | SGDID:S000000621 | ENPP5 UNQ550/PRO1107 |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-) |
3.1.-.- | Homo sapiens | Ceroid Lipofuscinosis, Neuronal, 6 |
5vem_b | Q9UJA9 | ENSG00000112796 | ENPP5 | 99.90 | 9.40E-32 | 7.60E-36 | 296.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YCR026C | NPP1 | SGDID:S000000621 | Enpp2 Atx Npps2 |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (E-NPP 2) (EC 3.1.4.39) (Autotaxin) (Extracellular lysophospholipase D) (LysoPLD) |
3.1.4.39 | Rattus norvegicus | 5dlt_a | Q64610 | 99.90 | 5.70E-33 | 4.50E-37 | 332.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YCR026C | NPP1 | SGDID:S000000621 | PDE |
Venom phosphodiesterase (PDE) (EC 3.6.1.-) |
Naja atra | 5gz4_a | A0A2D0TC04 | 99.90 | 2.30E-32 | 1.90E-36 | 327.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YCR026C | NPP1 | SGDID:S000000621 | pafA |
Alkaline phosphatase PafA (AP PafA) (EC 3.1.3.1) |
3.1.3.1 | Elizabethkingia meningoseptica | 5tj3_a | Q9KJX5 | 99.80 | 1.10E-24 | 8.50E-29 | 248.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |