YDL078C MDH3 / SGDID:S000002236
SGD CSV
Disease Associated
Homo Sapiens
Mus Musculus
Danio Rerio
Drosophila Melanogaster
Caenorhabditis Elegans
Arabidopsis Thaliana
Escherichia Coli
Yeast Systematic Name Yeast Symbol SGDID Analog Name Analog Description EC Organism Disease Structure Uniprot Human ID Human Symbol HHsearch Probability HHsearch E_value HHsearch P_value HHsearch Score Flag Disease related Flag Homo sapiens Flag Mus musculus Flag Danio rerio Flag Drosophila melanogaster Flag Caenorhabditis elegans Flag Arabidopsis thaliana Flag Escherichia coli
YDL078C MDH3 SGDID:S000002236
MDH2
Malate dehydrogenase, mitochondrial (EC 1.1.1.37)
 1.1.1.37 Sus scrofa
1mld_b P00346 99.80 2.50E-25 1.50E-29 180.20 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
MDH1 At1g04410 F19P19.13
Malate dehydrogenase 1, cytoplasmic (EC 1.1.1.37) (Cytosolic NAD-dependent malate dehydrogenase 1) (cNAD-MDH1) (Cytosolic malate dehydrogenase 1) (Cytosolic MDH1)
 1.1.1.37 Arabidopsis thaliana
5nue_a P93819 99.80 2.70E-25 1.60E-29 181.30 0 0 0 0 0 0 1 0
YDL078C MDH3 SGDID:S000002236
UEVLD UEV3
Ubiquitin-conjugating enzyme E2 variant 3 (UEV-3) (EV and lactate/malate dehydrogenase domain-containing protein)
 Homo sapiens
Chromosome 3q29 Deletion Syndrome
 2i6t_b Q8IX04 ENSG00000151116 UEVLD 99.80 3.00E-23 1.80E-27 166.60 1 1 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
L-lactate dehydrogenase
L-lactate dehydrogenase
 Apicomplexa
4plf_b A0A075B5G8 99.70 1.30E-22 7.70E-27 165.30 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
PF3D7_0618500
PF3D7_0618500
 Plasmodium falciparum
5nfr_e C6KT25 99.80 5.00E-26 3.00E-30 184.20 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
ldh TM_1867
L-lactate dehydrogenase (L-LDH) (EC 1.1.1.27)
 1.1.1.27 Thermotoga maritima
1a5z_a P16115 99.80 7.50E-26 4.40E-30 183.40 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
ldh1 SACOL0222
L-lactate dehydrogenase 1 (L-LDH 1) (EC 1.1.1.27)
 1.1.1.27 Staphylococcus aureus
3d0o_a Q5HJD7 99.90 1.90E-27 1.10E-31 192.80 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
ldha
L-lactate dehydrogenase A chain (LDH-A) (EC 1.1.1.27) (LDH-M)
 1.1.1.27 Squalus acanthias
3ldh_a P00341 99.70 7.90E-23 4.60E-27 166.00 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
mdh b3236 JW3205
Malate dehydrogenase (EC 1.1.1.37)
 1.1.1.37 Escherichia coli
1ie3_d P61889 99.80 7.30E-26 4.20E-30 183.20 0 0 0 0 0 0 0 1
YDL078C MDH3 SGDID:S000002236
mdh MexAM1_META1p1537
Malate dehydrogenase (EC 1.1.1.37)
 1.1.1.37 Methylorubrum extorquens
5ujk_a Q84FY8 99.80 4.50E-25 2.70E-29 178.80 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
mdh Mext_1643
Malate dehydrogenase (EC 1.1.1.37)
 1.1.1.37 Methylorubrum extorquens
4ror_a A9W386 99.80 4.50E-25 2.70E-29 178.80 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
ldh lctE BSU03050
L-lactate dehydrogenase (L-LDH) (EC 1.1.1.27)
 1.1.1.27 Bacillus subtilis
3pqe_d P13714 99.80 1.50E-25 8.60E-30 182.10 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
cgd7_480
cgd7_480
 Cryptosporidium parvum
4nd2_a Q5CYZ2 99.80 1.30E-23 7.60E-28 170.20 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
ldh EMQU_1380
ldh EMQU_1380
 1.1.1.27 Enterococcus mundtii
3wsv_d V5XPB8 99.90 7.80E-27 4.60E-31 189.50 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
LDHB
L-lactate dehydrogenase B chain (LDH-B) (EC 1.1.1.27) (LDH heart subunit) (LDH-H)
 1.1.1.27 Sus scrofa
5yta_b P00336 99.90 6.60E-27 3.90E-31 190.40 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
ldh DR_2364
L-lactate dehydrogenase (L-LDH) (EC 1.1.1.27) (2-ketoacid:NAD-dependent dehydrogenase)
 1.1.1.27 Deinococcus radiodurans
2v6b_b P50933 99.80 1.00E-23 5.80E-28 169.90 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
PF3D7_1324900
PF3D7_1324900
 Plasmodium falciparum
3zh2_c Q76NM3 99.70 2.70E-22 1.60E-26 162.00 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
mdh
Malate dehydrogenase (EC 1.1.1.37)
 1.1.1.37 Thermus thermophilus
1y7t_b P10584 99.90 6.40E-27 3.70E-31 190.60 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
mdh SRU_1571
Malate dehydrogenase (EC 1.1.1.37)
 1.1.1.37 Salinibacter ruber
3nep_x Q2S289 99.80 8.60E-26 5.00E-30 182.30 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
mdh
Malate dehydrogenase (EC 1.1.1.37)
 1.1.1.37 Aquaspirillum arcticum
1b8p_a Q9ZF99 99.90 1.20E-27 7.10E-32 194.90 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
ldh Cthe_0345
ldh Cthe_0345
 1.1.1.27 Hungateiclostridium thermocellum
1y6j_a A3DCA4 99.90 9.50E-27 5.50E-31 188.80 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
mdh AF_0855
Malate dehydrogenase (EC 1.1.1.37)
 1.1.1.37 Archaeoglobus fulgidus
2x0j_a O08349 99.70 5.20E-23 3.10E-27 164.70 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
MDH3 YDL078C D2468
Malate dehydrogenase, peroxisomal (EC 1.1.1.37)
 1.1.1.37 Saccharomyces cerevisiae
5zi2_a P32419 100.00 2.00E-34 1.20E-38 235.40 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
mdh BA_4837 GBAA_4837 BAS4486
Malate dehydrogenase (EC 1.1.1.37)
 1.1.1.37 Bacillus anthracis
3tl2_a Q6HSF4 99.70 3.50E-22 2.10E-26 161.40 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
ldh
L-lactate dehydrogenase (L-LDH) (EC 1.1.1.27)
 1.1.1.27 Thermus caldophilus
3vpg_a P06150 99.80 4.60E-25 2.70E-29 178.00 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
mdh Rv1240 MTV006.12
Malate dehydrogenase (EC 1.1.1.37)
 1.1.1.37 Mycobacterium tuberculosis
4tvo_a P9WK13 99.80 3.50E-26 2.10E-30 186.50 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
mdh HVO_3007
Malate dehydrogenase (EC 1.1.1.37)
 1.1.1.37 Haloferax volcanii
4bgu_a Q9P9L2 99.90 1.20E-27 6.90E-32 192.80 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
HA72_0455 MsedA_0468 MsedB_0468 MsedC_0467 MsedD_0468 MsedE_0468
HA72_0455 MsedA_0468 MsedB_0468 MsedC_0467 MsedD_0468 MsedE_0468
 Metallosphaera sedula
6ihe_a A0A088E2H7 99.80 1.30E-23 7.40E-28 168.90 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
ldh Bsel_2311
ldh Bsel_2311
 1.1.1.27 Bacillus selenitireducens
4m1q_a D6XW60 99.90 2.50E-27 1.50E-31 193.50 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
MDHP1
Malate dehydrogenase [NADP] 1, chloroplastic (EC 1.1.1.82) (NADP-MDH-1)
 1.1.1.82 Sorghum bicolor
7mdh_b P17606 99.90 1.10E-26 6.30E-31 192.60 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
ldh TTHA1113
L-lactate dehydrogenase (L-LDH) (EC 1.1.1.27)
 1.1.1.27 Thermus thermophilus
4a73_a Q5SJA1 99.80 4.70E-25 2.70E-29 177.90 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
ldh lct
L-lactate dehydrogenase (L-LDH) (EC 1.1.1.27)
 1.1.1.27 Geobacillus stearothermophilus
1ldn_f P00344 99.80 3.60E-26 2.10E-30 185.20 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
TGRH88_076470
TGRH88_076470
 Toxoplasma gondii
1pzg_b P90613 99.80 2.30E-25 1.40E-29 181.60 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
mdh
mdh
 1.1.1.37 Francisella tularensis
3p7m_b Q8G942 99.70 2.80E-22 1.60E-26 162.40 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
PGN_1880
PGN_1880
 Porphyromonas gingivalis
3fi9_a B2RM04 99.80 5.70E-26 3.30E-30 186.00 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
DHL2
L-2-hydroxyisocaproate dehydrogenase (L-HicDH) (EC 1.1.1.-)
 1.1.1.- Weissella confusa
1hyh_c P14295 99.70 5.20E-23 3.10E-27 165.80 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
cgd7_470
cgd7_470
 Cryptosporidium parvum
2hjr_c Q5CYZ3 99.80 5.90E-25 3.50E-29 178.70 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
LDHA PIG19
L-lactate dehydrogenase A chain (LDH-A) (EC 1.1.1.27) (Cell proliferation-inducing gene 19 protein) (LDH muscle subunit) (LDH-M) (Renal carcinoma antigen NY-REN-59)
 1.1.1.27 Homo sapiens
Myoglobinuria,Esophagus Carcinoma In Situ,Clear Cell Renal Cell Carcinoma,Prolapse Of Urethra,Leiomyomatosis,Glycogen Storage Disease,Stress Polycythemia,Burkitt Lymphoma,Breast Cancer,Colorectal Cancer,Septic Myocarditis,Subendocardial Myocardial Infarction,Fanconi-Bickel Syndrome,Hyperinsulinemic Hypoglycemia, Familial, 7,Breast Adenocarcinoma,Alzheimer Disease 13,Parkinson Disease 17,Renal Cell Carcinoma, Nonpapillary,Hereditary Leiomyomatosis And Renal Cell Cancer
 5w8j_b P00338 ENSG00000134333 LDHA 99.80 6.50E-26 3.90E-30 184.40 1 1 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
ldh ldhL
L-lactate dehydrogenase (L-LDH) (EC 1.1.1.27)
 1.1.1.27 Lactobacillus pentosus
1ez4_b P56511 99.90 1.30E-27 7.50E-32 193.70 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
ldh1 BC_1924
L-lactate dehydrogenase 1 (L-LDH 1) (EC 1.1.1.27)
 1.1.1.27 Bacillus cereus
4ln1_b Q81EP4 99.80 4.60E-26 2.70E-30 185.80 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
ldh Pmob_1893
L-lactate dehydrogenase (L-LDH) (EC 1.1.1.27)
 1.1.1.27 Petrotoga mobilis
6h9s_b A9BGZ9 99.80 7.80E-24 4.60E-28 170.50 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
MDH1
Malate dehydrogenase, cytoplasmic (EC 1.1.1.37) (Cytosolic malate dehydrogenase)
 1.1.1.37 Sus scrofa
4mdh_a P11708 99.90 5.40E-27 3.10E-31 191.70 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
cMDH LMJF_28_2860
cMDH LMJF_28_2860
 1.1.1.37 Leishmania major
4h7p_b Q4Q7X6 99.80 3.30E-26 1.90E-30 187.50 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
EMWEY_00056130
EMWEY_00056130
 Eimeria maxima
6ct6_a U6M598 99.80 8.80E-24 5.20E-28 172.30 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
LDH1 TVAG_495880
LDH1 TVAG_495880
 1.1.1.27 Trichomonas vaginalis
4uul_a O96445 99.80 3.20E-25 1.90E-29 181.50 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
MDHP
Malate dehydrogenase [NADP], chloroplastic (EC 1.1.1.82) (NADP-MDH)
 1.1.1.82 Flaveria bidentis
1civ_a P46489 99.90 4.40E-27 2.60E-31 194.90 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
mdh PTO0994
Malate dehydrogenase (EC 1.1.1.37)
 1.1.1.37 Picrophilus torridus
4bgv_c Q6L0C3 99.80 2.60E-26 1.50E-30 186.20 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
mdh
Malate dehydrogenase (EC 1.1.1.37)
 1.1.1.37 Prosthecochloris vibrioformis
1guz_d P0C890 99.80 4.40E-25 2.60E-29 178.10 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
LDH
L-lactate dehydrogenase (EC 1.1.1.27) (LDH-P)
 1.1.1.27 Plasmodium falciparum
4plz_a Q27743 99.80 4.10E-23 2.40E-27 167.20 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
mdh APE_0672.1
Malate dehydrogenase (EC 1.1.1.299)
 1.1.1.299 Aeropyrum pernix
2d4a_c Q9YEA1 99.80 4.60E-26 2.70E-30 183.50 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
ldh
ldh
 Firmicutes bacterium
4q3n_a A0A0B5KUB4 99.80 1.50E-24 9.00E-29 175.20 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
ldh2 BLLJ_1290
L-lactate dehydrogenase 2 (L-LDH 2) (EC 1.1.1.27) (FBP-dependent LDH)
 1.1.1.27 Bifidobacterium longum
1lld_a E8ME30 99.80 3.80E-26 2.20E-30 185.30 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
MDHG
Malate dehydrogenase, glyoxysomal (EC 1.1.1.37)
 1.1.1.37 Citrullus lanatus
1smk_h P19446 99.90 7.30E-28 4.30E-32 195.90 0 0 0 0 0 0 0 0
YDL078C MDH3 SGDID:S000002236
mdh mdhB MJ0490
L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) (EC 1.1.1.375) (MdhII)
 1.1.1.375 Methanocaldococcus jannaschii
1hye_a Q60176 99.80 2.70E-24 1.60E-28 173.90 0 0 0 0 0 0 0 0