| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YDL120W | YFH1 | SGDID:S000002278 | YFH1 YDL120W |
Frataxin homolog, mitochondrial (EC 1.16.3.1) [Cleaved into: Frataxin homolog intermediate form] |
1.16.3.1 | Saccharomyces cerevisiae | 3oeq_a | Q07540 | 100.00 | 3.70E-36 | 3.10E-40 | 227.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YDL120W | YFH1 | SGDID:S000002278 | CTHT_0015430 |
CTHT_0015430 |
1.16.3.1 | Chaetomium thermophilum | 6fco_b | G0S1Z8 | 99.90 | 1.40E-32 | 1.10E-36 | 209.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YDL120W | YFH1 | SGDID:S000002278 | cyaY Ping_0042 |
Iron-sulfur cluster assembly protein CyaY |
Psychromonas ingrahamii | 4hs5_b | A1SR01 | 99.90 | 2.00E-32 | 1.70E-36 | 201.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YDL120W | YFH1 | SGDID:S000002278 | FXN FRDA X25 |
Frataxin, mitochondrial (EC 1.16.3.1) (Friedreich ataxia protein) (Fxn) [Cleaved into: Frataxin intermediate form (i-FXN); Frataxin(56-210) (m56-FXN); Frataxin(78-210) (d-FXN) (m78-FXN); Frataxin mature form (Frataxin(81-210)) (m81-FXN)] |
1.16.3.1 | Homo sapiens | Bone Structure Disease,Heart Disease,Sideroblastic Anemia,Retinitis Pigmentosa,Optic Nerve Disease,Diabetes Mellitus,Neuromuscular Disease,Hypertrophic Cardiomyopathy,Myotonic Disease,Myotonic Dystrophy 1,Neurodegeneration With Brain Iron Accumulation,Spastic Ataxia, Charlevoix-Saguenay Type,Tertiary Neurosyphilis,Mitochondrial Dna Depletion Syndrome 7,Sensory Peripheral Neuropathy,Choreatic Disease,Spinocerebellar Ataxia 1,Tabes Dorsalis,Mitochondrial Complex Iii Deficiency, Nuclear Type 2,Cerebellar Disease,Mitochondrial Disorders,Friedreich Ataxia 2,Peripheral Nervous System Disease,Ataxia With Vitamin 3 Deficiency,Myotonic Dystrophy 2,Deficiency Anemia,Autosomal Dominant Cerebellar Ataxia,Spinocerebellar Ataxia 10,Friedreich Ataxia,Disease Of Mental Health,Dentatorubral-Pallidoluysian Atrophy,Aceruloplasminemia,Mental Retardation, X-Linked, With Cerebellar Hypoplasia And Distinctive Facial Appearance,Hemochromatosis, Type 1,Fragile X Syndrome,Anemia, Sideroblastic, 1,Spinocerebellar Ataxia 6,Spinocerebellar Ataxia, Autosomal Recessive, With Axonal Neuropathy 2,Neurodegeneration With Brain Iron Accumulation 3,Autosomal Recessive Disease,Autosomal Genetic Disease,Anemia, Sideroblastic, And Spinocerebellar Ataxia,Perrault Syndrome,Fragile X-Associated Tremor/Ataxia Syndrome,Marinesco-Sjogren Syndrome,Autosomal Recessive Cerebellar Ataxia,Hereditary Ataxia,Spastic Ataxia,X-Linked Hereditary Ataxia,Leber Hereditary Optic Neuropathy, Modifier Of,Mitochondrial Complex I Deficiency, Nuclear Type 1,Scoliosis,Spinal And Bulbar Muscular Atrophy, X-Linked 1,Ataxia, Early-Onset, With Oculomotor Apraxia And Hypoalbuminemia,Kearns-Sayre Syndrome,Leigh Syndrome,3-Methylglutaconic Aciduria, Type Iii |
3t3l_a | Q16595 | ENSG00000165060 | FXN | 99.90 | 2.90E-33 | 2.40E-37 | 213.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YDL120W | YFH1 | SGDID:S000002278 | ISU1 NUA1 YPL135W |
Iron sulfur cluster assembly protein 1, mitochondrial (Iron sulfur cluster scaffold protein 1) |
Saccharomyces cerevisiae | 5tre_l | Q03020 | 100.00 | 1.40E-35 | 1.10E-39 | 223.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YDL120W | YFH1 | SGDID:S000002278 | cyaY BceJ2315_02750 BCAL0273 |
Iron-sulfur cluster assembly protein CyaY |
Burkholderia cenocepacia | 4jpd_a | B4E5Z6 | 99.90 | 1.30E-33 | 1.10E-37 | 209.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YDL120W | YFH1 | SGDID:S000002278 | FXN FRDA X25 |
Frataxin, mitochondrial (EC 1.16.3.1) (Friedreich ataxia protein) (Fxn) [Cleaved into: Frataxin intermediate form (i-FXN); Frataxin(56-210) (m56-FXN); Frataxin(78-210) (d-FXN) (m78-FXN); Frataxin mature form (Frataxin(81-210)) (m81-FXN)] |
1.16.3.1 | Homo sapiens | Bone Structure Disease,Heart Disease,Sideroblastic Anemia,Retinitis Pigmentosa,Optic Nerve Disease,Diabetes Mellitus,Neuromuscular Disease,Hypertrophic Cardiomyopathy,Myotonic Disease,Myotonic Dystrophy 1,Neurodegeneration With Brain Iron Accumulation,Spastic Ataxia, Charlevoix-Saguenay Type,Tertiary Neurosyphilis,Mitochondrial Dna Depletion Syndrome 7,Sensory Peripheral Neuropathy,Choreatic Disease,Spinocerebellar Ataxia 1,Tabes Dorsalis,Mitochondrial Complex Iii Deficiency, Nuclear Type 2,Cerebellar Disease,Mitochondrial Disorders,Friedreich Ataxia 2,Peripheral Nervous System Disease,Ataxia With Vitamin 3 Deficiency,Myotonic Dystrophy 2,Deficiency Anemia,Autosomal Dominant Cerebellar Ataxia,Spinocerebellar Ataxia 10,Friedreich Ataxia,Disease Of Mental Health,Dentatorubral-Pallidoluysian Atrophy,Aceruloplasminemia,Mental Retardation, X-Linked, With Cerebellar Hypoplasia And Distinctive Facial Appearance,Hemochromatosis, Type 1,Fragile X Syndrome,Anemia, Sideroblastic, 1,Spinocerebellar Ataxia 6,Spinocerebellar Ataxia, Autosomal Recessive, With Axonal Neuropathy 2,Neurodegeneration With Brain Iron Accumulation 3,Autosomal Recessive Disease,Autosomal Genetic Disease,Anemia, Sideroblastic, And Spinocerebellar Ataxia,Perrault Syndrome,Fragile X-Associated Tremor/Ataxia Syndrome,Marinesco-Sjogren Syndrome,Autosomal Recessive Cerebellar Ataxia,Hereditary Ataxia,Spastic Ataxia,X-Linked Hereditary Ataxia,Leber Hereditary Optic Neuropathy, Modifier Of,Mitochondrial Complex I Deficiency, Nuclear Type 1,Scoliosis,Spinal And Bulbar Muscular Atrophy, X-Linked 1,Ataxia, Early-Onset, With Oculomotor Apraxia And Hypoalbuminemia,Kearns-Sayre Syndrome,Leigh Syndrome,3-Methylglutaconic Aciduria, Type Iii |
1ekg_a | Q16595 | 100.00 | 1.30E-35 | 1.10E-39 | 224.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| YDL120W | YFH1 | SGDID:S000002278 | ISCU NIFUN |
Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (NifU-like N-terminal domain-containing protein) (NifU-like protein) |
Homo sapiens | Multiple Mitochondrial Dysfunctions Syndrome,Myopathy,Mitochondrial Myopathy,Cerebellar Disease,Myopathy With Deficiency Of Iscu,Siderosis,Combined Oxidative Phosphorylation Deficiency 19,Lactic Acidosis,Anemia, Sideroblastic, 1,Multiple Mitochondrial Dysfunctions Syndrome 1,Mend Syndrome,Anemia, Sideroblastic, And Spinocerebellar Ataxia,Autosomal Recessive Cerebellar Ataxia,Myopathy With Lactic Acidosis, Hereditary |
5kz5_b | Q9H1K1 | ENSG00000136003 | ISCU | 100.00 | 1.90E-37 | 1.50E-41 | 246.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |