YDL243C AAD4 / SGDID:S000002402
SGD CSV
Disease Associated
Homo Sapiens
Mus Musculus
Danio Rerio
Drosophila Melanogaster
Caenorhabditis Elegans
Arabidopsis Thaliana
Escherichia Coli
Yeast Systematic Name Yeast Symbol SGDID Analog Name Analog Description EC Organism Disease Structure Uniprot Human ID Human Symbol HHsearch Probability HHsearch E_value HHsearch P_value HHsearch Score Flag Disease related Flag Homo sapiens Flag Mus musculus Flag Danio rerio Flag Drosophila melanogaster Flag Caenorhabditis elegans Flag Arabidopsis thaliana Flag Escherichia coli
YDL243C AAD4 SGDID:S000002402
Kcnab2 Ckbeta2 Kcnb3
Voltage-gated potassium channel subunit beta-2 (EC 1.1.1.-) (K(+) channel subunit beta-2) (Kv-beta-2)
 1.1.1.- Rattus norvegicus
1exb_a P62483 100.00 1.50E-44 9.50E-49 305.60 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
YPO2805
YPO2805
 1.1.1.- Yersinia pestis
4mhb_c Q7CJX8 100.00 3.20E-43 2.00E-47 292.00 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
gpr_2 CBEIJ_11710
gpr_2 CBEIJ_11710
 Clostridium beijerinckii
6hg6_a A0A1S8QGT2 100.00 2.90E-42 1.80E-46 291.30 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
yvgN BSU33400
Glyoxal reductase (GR) (EC 1.1.1.-) (Methylglyoxal reductase) (EC 1.1.1.283)
 1.1.1.283 Bacillus subtilis
3f7j_b O32210 100.00 6.10E-41 3.90E-45 275.70 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
PR
Perakine reductase (EC 1.1.1.317)
 1.1.1.317 Rauvolfia serpentina
3uyi_a Q3L181 100.00 8.40E-45 5.30E-49 307.40 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
PGFS
9,11-endoperoxide prostaglandin H2 reductase (EC 1.1.1.-) (Prostaglandin F2-alpha synthase)
 1.1.1.- Trypanosoma brucei
1vbj_a Q9GV41 100.00 1.10E-41 7.10E-46 280.70 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
AKR1D1 SRD5B1
Aldo-keto reductase family 1 member D1 (EC 1.3.1.3) (3-oxo-5-beta-steroid 4-dehydrogenase) (Delta(4)-3-ketosteroid 5-beta-reductase) (Delta(4)-3-oxosteroid 5-beta-reductase)
 1.3.1.3 Homo sapiens
Liver Disease,Cholestasis-Lymphedema Syndrome,Leber Plus Disease,Bile Acid Synthesis Defect, Congenital, 3,Bile Acid Synthesis Defect, Congenital, 2,Congenital Bile Acid Synthesis Defect,Alpha-Methylacyl-Coa Racemase Deficiency
 3buv_a P51857 ENSG00000122787 AKR1D1 100.00 1.10E-40 7.20E-45 280.90 1 1 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
cpr-c2
NADPH-dependent conjugated polyketone reductase C2 (CPR) (2-dehydropantolactone reductase) (EC 1.1.1.358) (2-dehydropantolactone reductase (A-specific)) (EC 1.1.1.168) (Ketopantoyl-lactone reductase)
 1.1.1.168,1.1.1.358, Candida parapsilosis
3vxg_a Q76L36 100.00 1.90E-43 1.20E-47 297.50 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
XR
XR
 Debaryomyces nepalensis
5zcm_a A0A0M4HL56 100.00 6.50E-40 4.10E-44 277.30 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
Aldo_ket_red domain-containing protein
Aldo_ket_red domain-containing protein
 Bombyx mori
5az0_a H9JJU9 100.00 1.90E-41 1.20E-45 288.10 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
Bpro_4249
Bpro_4249
 Polaromonas
4xk2_a Q124A1 100.00 2.70E-44 1.70E-48 305.50 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
SMc01429
SMc01429
 1.1.1.- Rhizobium meliloti
4pmj_a Q92NR7 100.00 8.90E-43 5.60E-47 287.50 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
P100/11E
9,11-endoperoxide prostaglandin H2 reductase (EC 1.1.1.-) (Prostaglandin F2-alpha synthase)
 1.1.1.- Leishmania major
4f40_b P22045 100.00 2.50E-40 1.60E-44 273.80 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
GOX1615
GOX1615
 1.1.1.- Gluconobacter oxydans
3n2t_a Q5FQJ0 100.00 3.00E-44 1.90E-48 304.70 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
Aldo-keto reductase
Aldo-keto reductase
 Firmicutes bacterium
4q3m_d A0A0B5KNF6 100.00 5.50E-42 3.50E-46 282.00 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
GL50803_007260 GL50803_7260
GL50803_007260 GL50803_7260
 1.1.1.21 Giardia intestinalis
3krb_a A8BGX6 100.00 3.90E-41 2.40E-45 284.20 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
Rv2971
Uncharacterized oxidoreductase Rv2971 (EC 1.-.-.-)
 Mycobacterium tuberculosis
4otk_a P9WQA5 100.00 2.80E-43 1.80E-47 294.30 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
STM2406
STM2406
 Salmonella typhimurium
3erp_b Q8ZNA1 100.00 8.10E-45 5.10E-49 309.30 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
dkgA
2,5-diketo-D-gluconic acid reductase A (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (EC 1.1.1.346) (AKR5C)
 1.1.1.346 Corynebacterium sp.
1a80_a P06632 100.00 1.70E-41 1.00E-45 279.40 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
Tc00.1047053511287.49
9,11-endoperoxide prostaglandin H2 reductase (EC 1.1.1.-) (Prostaglandin F2-alpha synthase)
 1.1.1.- Trypanosoma cruzi
4gie_a Q4DJ07 100.00 2.50E-41 1.60E-45 279.70 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
TM_1743
TM_1743
 Thermotoga maritima
5dan_a Q9X265 100.00 9.70E-43 6.10E-47 286.80 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
MSMEG_2407 MSMEI_2346
Uncharacterized oxidoreductase MSMEG_2407/MSMEI_2346 (EC 1.-.-.-)
 Mycolicibacterium smegmatis
2wzm_b A0QV09 100.00 3.70E-40 2.30E-44 272.00 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
ydhF b1647 JW1639
Oxidoreductase YdhF (EC 1.-.-.-)
 Escherichia coli
1og6_c P76187 100.00 1.00E-43 6.50E-48 296.10 0 0 0 0 0 0 0 1
YDL243C AAD4 SGDID:S000002402
Akr7a2 Afar Akr7a5
Aflatoxin B1 aldehyde reductase member 2 (EC 1.1.1.n11) (Succinic semialdehyde reductase) (SSA reductase)
 1.1.1.n11 Mus musculus
2c91_c Q8CG76 100.00 7.80E-43 5.00E-47 295.10 0 0 1 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
ytbE BSU29050
Uncharacterized oxidoreductase YtbE (EC 1.-.-.-)
 Bacillus subtilis
3b3d_c O34678 100.00 9.10E-42 5.70E-46 284.80 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
CHR
CHR
 Medicago sativa
1zgd_a Q40309 100.00 1.90E-41 1.20E-45 283.90 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
Akr1a1 Akr1a4
Aldo-keto reductase family 1 member A1 (EC 1.1.1.2) (EC 1.1.1.33) (EC 1.1.1.372) (EC 1.1.1.54) (Alcohol dehydrogenase [NADP(+)]) (Aldehyde reductase) (Glucuronate reductase) (EC 1.1.1.19) (Glucuronolactone reductase) (EC 1.1.1.20)
 1.1.1.19,1.1.1.2,1.1.1.20,1.1.1.33,1.1.1.372,1.1.1.54, Mus musculus
4gac_b Q9JII6 100.00 4.00E-40 2.50E-44 277.40 0 0 1 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
AKR1C2 DDH2
Aldo-keto reductase family 1 member C2 (EC 1.-.-.-) (EC 1.1.1.112) (EC 1.1.1.209) (EC 1.1.1.53) (EC 1.1.1.62) (EC 1.3.1.20) (3-alpha-HSD3) (Chlordecone reductase homolog HAKRD) (Dihydrodiol dehydrogenase 2) (DD-2) (DD2) (Dihydrodiol dehydrogenase/bile acid-binding protein) (DD/BABP) (Type III 3-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.357)
 1.1.1.357,1.3.1.20, Homo sapiens
Inclusion Body Myopathy With Early-Onset Paget Disease Of Bone With Or Without Frontotemporal Dementia 2,Inclusion Body Myopathy With Early-Onset Paget Disease Of Bone With Or Without Frontotemporal Dementia 1,Inclusion Body Myopathy With Early-Onset Paget Disease Of Bone With Or Without Frontotemporal Dementia 3,Parasitic Protozoa Infectious Disease,Glucosephosphate Dehydrogenase Deficiency,Colorectal Cancer, Hereditary Nonpolyposis, Type 2,Mixed Malaria,46,Xy Sex Reversal,Lynch Syndrome I,Prostate Cancer,Body Mass Index Quantitative Trait Locus 11,Pseudohermaphroditism,Bile Acid Synthesis Defect, Congenital, 2,Malaria,46,Xy Sex Reversal 8,Inclusion Body Myopathy With Paget Disease Of Bone And Frontotemporal Dementia
 4l1w_b P52895 ENSG00000151632 AKR1C2 100.00 4.10E-41 2.60E-45 283.30 1 1 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
cpr-c1
NADPH-dependent conjugated polyketone reductase C1 (CPR) (2-dehydropantolactone reductase (A-specific)) (EC 1.1.1.168) (Ketopantoyl-lactone reductase)
 1.1.1.168 Candida parapsilosis
3wg6_a Q76L37 100.00 7.50E-41 4.80E-45 279.60 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
Aldo-keto reductase 1
Aldo-keto reductase 1
 Coptotermes gestroi
5ket_a A0A140CVV2 100.00 1.50E-39 9.50E-44 275.00 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
akr2e AKR2E4
Aldo-keto reductase AKR2E4 (EC 1.1.1.-) (3-dehydroecdysone reductase) (Aldo-keto reductase 2E)
 1.1.1.- Bombyx mori
3wcz_a H9JTG9 100.00 1.80E-41 1.10E-45 283.60 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
BAB2_0177
BAB2_0177
 1.1.1.- Brucella abortus
3o0k_a Q2YII2 100.00 1.30E-40 8.10E-45 274.70 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
dkgB SMc00101
dkgB SMc00101
 1.1.1.274 Rhizobium meliloti
3up8_a Q92RC6 100.00 4.60E-41 2.90E-45 279.10 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
iolS yxbF BSU39780 SS92ER
Aldo-keto reductase IolS (EC 1.1.1.-) (AKR11A) (Vegetative protein 147) (VEG147)
 1.1.1.- Bacillus subtilis
1pz0_a P46336 100.00 4.40E-44 2.80E-48 300.20 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
GOX0644
GOX0644
 1.1.1.- Gluconobacter oxydans
3wbw_a Q5FT75 100.00 1.30E-41 8.00E-46 280.70 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
CCNA_02590
CCNA_02590
 Caulobacter vibrioides
6gtm_b A0A0H3C9H2 100.00 3.40E-42 2.20E-46 287.60 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
AR3 100857058 ZEAMMB73_Zm00001d038449
AR3 100857058 ZEAMMB73_Zm00001d038449
 Zea mays
5jgw_a E9JVD4 100.00 1.80E-40 1.10E-44 278.80 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
AKR4C9 At2g37770 F13M22 T8P21.32
NADPH-dependent aldo-keto reductase, chloroplastic (AtChlAKR) (EC 1.1.1.-) (Aldo-keto reductase family 4 member C9)
 1.1.1.- Arabidopsis thaliana
3h7u_a Q0PGJ6 100.00 9.20E-41 5.80E-45 281.20 0 0 0 0 0 0 1 0
YDL243C AAD4 SGDID:S000002402
ydhF STM1439
ydhF STM1439
 Salmonella typhimurium
4r9o_b Q8ZPN5 100.00 9.70E-43 6.10E-47 290.70 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
AKR1B1 ALDR1 ALR2
Aldo-keto reductase family 1 member B1 (EC 1.1.1.300) (EC 1.1.1.372) (EC 1.1.1.54) (Aldehyde reductase) (Aldose reductase) (AR) (EC 1.1.1.21)
 1.1.1.21,1.1.1.300,1.1.1.372,1.1.1.54, Homo sapiens
Severe Nonproliferative Diabetic Retinopathy,Autonomic Nervous System Disease,Diabetic Autonomic Neuropathy,Autonomic Neuropathy,American Histoplasmosis,Hyperglycemia,Diabetic Macular Edema,Microvascular Complications Of Diabetes 5,Polyradiculopathy,Diabetes Mellitus,Transient Refractive Change,Macular Retinal Edema,Alzheimer Disease,Constipation,Punctate Epithelial Keratoconjunctivitis,Diabetic Neuropathy,Keratopathy,Retinal Vascular Disease,Sensory Peripheral Neuropathy,Diabetic Polyneuropathy,Cataract,Retinal Degeneration,Corneal Disease,Type 1 Diabetes Mellitus,Background Diabetic Retinopathy,Diabetic Cataract,Kidney Disease,Neuropathy,Mature Cataract,Peripheral Nervous System Disease,Polyneuropathy,Lens Disease,Retinal Microaneurysm,Galactosemia I,Microvascular Complications Of Diabetes 1,Body Mass Index Quantitative Trait Locus 11,Type 2 Diabetes Mellitus,Ophthalmomyiasis,Pigmentary Disorder, Reticulate, With Systemic Manifestations, X-Linked,Hypertension, Essential,Membranous Nephropathy,Asthma
 3m64_a P15121 ENSG00000085662 AKR1B1 100.00 2.30E-40 1.50E-44 277.70 1 1 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
Akr1b4 EWB00_003887
Akr1b4 EWB00_003887
 1.1.1.21 Schistosoma japonicum
4hbk_a Q5DD64 100.00 6.60E-41 4.20E-45 283.30 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
Akr1c9
3-alpha-hydroxysteroid dehydrogenase (3-alpha-HSD) (EC 1.1.1.50) (Hydroxyprostaglandin dehydrogenase)
 1.1.1.50 Rattus norvegicus
1afs_a P23457 100.00 4.20E-50 2.70E-54 336.80 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
yeaE KPN_01195
yeaE KPN_01195
 Klebsiella pneumoniae
6cia_a A6T7Q7 100.00 1.60E-42 1.00E-46 286.70 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
yhdN BSU09530
Aldo-keto reductase YhdN (EC 1.1.1.-) (AKR11B) (General stress protein 69) (GSP69)
 1.1.1.- Bacillus subtilis
1pz1_b P80874 100.00 9.80E-44 6.20E-48 300.30 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
Akr1c13
Aldo-keto reductase family 1 member C13 (EC 1.1.1.-)
 1.1.1.- Mus musculus
6m7k_a Q8VC28 100.00 6.70E-42 4.30E-46 287.70 0 0 1 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
XYL1 XYLR
NAD(P)H-dependent D-xylose reductase (XR) (EC 1.1.1.307)
 1.1.1.307 Candida tenuis
1z9a_b O74237 100.00 7.80E-41 4.90E-45 281.10 0 0 0 0 0 0 0 0
YDL243C AAD4 SGDID:S000002402
gpr mgrA yghZ b3001 JW2970
L-glyceraldehyde 3-phosphate reductase (GAP reductase) (EC 1.1.1.-)
 1.1.1.- Escherichia coli
3n6q_e Q46851 100.00 3.80E-43 2.40E-47 298.30 0 0 0 0 0 0 0 1
YDL243C AAD4 SGDID:S000002402
BH1011
BH1011
 Bacillus halodurans
1ynp_b Q9KE47 100.00 1.10E-41 6.80E-46 285.70 0 0 0 0 0 0 0 0