| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YDR148C | KGD2 | SGDID:S000002555 | sucB b0727 JW0716 |
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2) (OGDC-E2) (Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex) |
2.3.1.61 | Escherichia coli | 6pbr_d | P0AFG6 | 100.00 | 2.90E-41 | 2.30E-45 | 318.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
| YDR148C | KGD2 | SGDID:S000002555 | pdhC |
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (E2) |
2.3.1.12 | Geobacillus stearothermophilus | 1b5s_a | P11961 | 100.00 | 2.60E-54 | 1.90E-58 | 407.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YDR148C | KGD2 | SGDID:S000002555 | aceF ECs_0119 |
aceF ECs_0119 |
2.3.1.12 | Escherichia coli | 4n72_c | Q8X966 | 100.00 | 1.80E-41 | 1.40E-45 | 322.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
| YDR148C | KGD2 | SGDID:S000002555 | DBT |
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase) |
2.3.1.168 | Bos taurus | 2ii3_c | P11181 | 100.00 | 1.20E-41 | 9.10E-46 | 326.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YDR148C | KGD2 | SGDID:S000002555 | DLAT DLTA |
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (M2 antigen complex 70 kDa subunit) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2) |
2.3.1.12 | Homo sapiens | Liver Disease,Nystagmus 7, Congenital, Autosomal Dominant,Chronic Cholangitis,Cholangitis,Autoimmune Hepatitis,Mycobacterium Gordonae,Autoimmune Cholangitis,Ulnar Neuropathy,Ulnar Nerve Lesion,Vaginitis,Primary Biliary Cholangitis,Biliary Tract Disease,Nystagmus 2, Congenital, Autosomal Dominant,Autoimmune Disease,Chancroid,Suppurative Cholangitis,Lactic Acidosis,Cholangitis, Primary Sclerosing,Halothane Hepatitis,Pyruvate Dehydrogenase E2 Deficiency,Nystagmus 4, Congenital, Autosomal Dominant,Autoimmune Disease Of Gastrointestinal Tract,Pyruvate Dehydrogenase E1-Alpha Deficiency |
3b8k_a | P10515 | ENSG00000150768 | DLAT | 100.00 | 5.40E-41 | 4.20E-45 | 317.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YDR148C | KGD2 | SGDID:S000002555 | PDHX PDX1 |
Pyruvate dehydrogenase protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (E3BP) (Lipoyl-containing pyruvate dehydrogenase complex component X) (proX) |
Homo sapiens | Primary Biliary Cholangitis,Lactic Acidosis,Pyruvate Dehydrogenase E3-Binding Protein Deficiency,Pyruvate Dehydrogenase E1-Alpha Deficiency,Leigh Syndrome |
6h60_a | O00330 | ENSG00000110435 | PDHX | 100.00 | 2.20E-53 | 1.70E-57 | 444.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YDR148C | KGD2 | SGDID:S000002555 | pdhC |
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (E2) |
2.3.1.12 | Geobacillus stearothermophilus | 1b5s_c | P11961 | 100.00 | 3.40E-41 | 2.70E-45 | 319.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YDR148C | KGD2 | SGDID:S000002555 | ODP2 |
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (E2) |
2.3.1.12 | Azotobacter vinelandii | 1ead_a | P10802 | 100.00 | 1.90E-41 | 1.50E-45 | 321.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |