Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
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YDR162C | NBP2 | SGDID:S000002569 | HCK |
Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck) |
2.7.10.2 | Homo sapiens | Leukemia, Chronic Myeloid,Tinea Favosa,Renal Pelvis Adenocarcinoma,Leukemia, Acute Lymphoblastic,Human Immunodeficiency Virus Type 1,Co-Trimoxazole Allergy,Immune Deficiency Disease |
2hck_b | P08631 | ENSG00000101336 | HCK | 95.00 | 0.00031 | 3.60E-08 | 58.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YDR162C | NBP2 | SGDID:S000002569 | DOCK2 KIAA0209 |
Dedicator of cytokinesis protein 2 |
Homo sapiens | Lymphopenia,Combined Immunodeficiency,Dendritic Cell Deficiency,Immunodeficiency 19,Immunodeficiency 40,Coronin-1a Deficiency |
2rqr_a | Q92608 | ENSG00000134516 | DOCK2 | 95.70 | 8.70E-05 | 9.70E-09 | 51.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
YDR162C | NBP2 | SGDID:S000002569 | FYB1 FYB SLAP130 |
FYN-binding protein 1 (Adhesion and degranulation promoting adaptor protein) (ADAP) (FYB-120/130) (p120/p130) (FYN-T-binding protein) (SLAP-130) (SLP-76-associated phosphoprotein) |
Homo sapiens | Rh Isoimmunization,Blood Group Incompatibility,Otopalatodigital Syndrome Spectrum Disorder,Congenital Autosomal Recessive Small-Platelet Thrombocytopenia,Glucosephosphate Dehydrogenase Deficiency,Thrombocytopenia 3,Hereditary Thrombocytopenia With Normal Platelets,Thrombocytopenia,Melnick-Needles Syndrome |
2gtj_a | O15117 | ENSG00000082074 | FYB1 | 98.00 | 2.20E-09 | 2.00E-13 | 80.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
YDR162C | NBP2 | SGDID:S000002569 | TP53BP2 ASPP2 BBP |
Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2) |
Homo sapiens | Chromosome 1q41-Q42 Deletion Syndrome,Lung Cancer |
6ghm_d | Q13625 | ENSG00000143514 | TP53BP2 | 95.30 | 0.00018 | 2.10E-08 | 53.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
YDR162C | NBP2 | SGDID:S000002569 | NEB |
Nebulin |
Homo sapiens | Muscular Disease,Childhood-Onset Nemaline Myopathy,Congenital Fiber-Type Disproportion,Congenital Structural Myopathy,Myopathy,Myofibrillar Myopathy,Congenital Nemaline Myopathy,Muscle Tissue Disease,Neuromuscular Disease,Bethlem Myopathy 1,Distal Nebulin Myopathy,Myositis,Myopathy, Myofibrillar, 1,Nemaline Myopathy 3,Muscular Dystrophy,Tibial Muscular Dystrophy,Hyaline Body Myopathy,Reducing Body Myopathy,Severe Congenital Nemaline Myopathy,Intermediate Congenital Nemaline Myopathy,Typical Congenital Nemaline Myopathy,Nemaline Myopathy,Myopathy, Myofibrillar, 4,Endocardial Fibroelastosis,Dysphagia,Foot Drop,Centronuclear Myopathy,Myopathy, Myofibrillar, 9, With Early Respiratory Failure,Central Core Myopathy,Myopathy, Spheroid Body,Strabismus,Primary Cutaneous Amyloidosis,Distal Arthrogryposis,Cardioneuromyopathy With Hyaline Masses And Nemaline Rods,Cardiomyopathy, Familial Hypertrophic, 1,Multiple Pterygium Syndrome, Lethal Type,Camptodactyly-Arthropathy-Coxa Vara-Pericarditis Syndrome,Left Ventricular Noncompaction,Batten-Turner Congenital Myopathy,Nemaline Myopathy 2,Multiple Pterygium Syndrome, Escobar Variant |
1ark_a | P20929 | 98.30 | 1.40E-10 | 1.30E-14 | 79.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR162C | NBP2 | SGDID:S000002569 | Btk Bpk |
Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase) (Kinase EMB) |
2.7.10.2 | Mus musculus | 4xi2_a | P35991 | 95.30 | 0.0002 | 2.30E-08 | 59.70 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
YDR162C | NBP2 | SGDID:S000002569 | SRC SRC1 |
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src) |
2.7.10.2 | Homo sapiens | Pancreatic Adenocarcinoma,Bone Disease,Skin Melanoma,Differentiating Neuroblastoma,Cryptococcal Meningitis,Retinitis Pigmentosa,Myeloid And Lymphoid Neoplasms Associated With Fgfr1 Abnormalities,Lung Cancer Susceptibility 3,Myopathy,Polycystic Kidney Disease,Leukemia, Chronic Myeloid,Gastroesophageal Adenocarcinoma,Bone Sarcoma,Hepatitis B,Rasopathy,Avian Influenza,Myocardial Infarction,Teeth Hard Tissue Disease,Amelogenesis Imperfecta,Essential Thrombocythemia,Neuroblastoma,Leukemia, Acute Myeloid,Cystic Fibrosis,Bone Marrow Cancer,Leukemia, Acute Lymphoblastic,Agammaglobulinemia,Autonomic Nervous System Neoplasm,Bladder Cancer,Osteoporosis,Ovarian Cancer,Pylorus Cancer,Osteopetrosis,Breast Cancer,Glioblastoma,Squamous Cell Carcinoma, Head And Neck,Diamond-Blackfan Anemia 10,Anaplastic Astrocytoma,Colorectal Cancer,Peripheral Nervous System Disease,Hepatocellular Carcinoma,Human Immunodeficiency Virus Type 1,Noonan Syndrome With Multiple Lentigines,Alzheimer Disease 11,Cherubism,Sarcoma,Skin Carcinoma,Cone-Rod Dystrophy 2,Alzheimer Disease 18,Tetanus,Prostate Cancer,Disease Of Mental Health,Signet Ring Cell Adenocarcinoma,Body Mass Index Quantitative Trait Locus 11,Thrombocytopenia,Lynch Syndrome,Lung Squamous Cell Carcinoma,Agammaglobulinemia, X-Linked,Hypotrichosis 1,Wiskott-Aldrich Syndrome,Maturity-Onset Diabetes Of The Young,Acute Promyelocytic Leukemia,Pulmonary Disease, Chronic Obstructive,Hypertension, Essential,Meningioma, Familial,Frank-Ter Haar Syndrome,Estrogen-Receptor Positive Breast Cancer,Estrogen-Receptor Negative Breast Cancer,Coenzyme Q10 Deficiency, Primary, 1,Amelogenesis Imperfecta, Type Ig,Thrombocytopenia 6,Myelofibrosis,Myeloma, Multiple,Medulloblastoma,Lung Cancer,Pancreatic Cancer,Polycythemia Vera |
1y57_a | P12931 | ENSG00000197122 | SRC | 95.90 | 4.40E-05 | 5.10E-09 | 63.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YDR162C | NBP2 | SGDID:S000002569 | Itsn1 Ese1 Itsn |
Intersectin-1 (EH and SH3 domains protein 1) |
Mus musculus | 3jv3_a | Q9Z0R4 | 96.20 | 2.20E-05 | 2.60E-09 | 61.30 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | ||||
YDR162C | NBP2 | SGDID:S000002569 | ABL1 ABL JTK7 |
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150) |
2.7.10.2 | Homo sapiens | Heart Disease,Childhood Acute Lymphocytic Leukemia,Childhood T-Cell Acute Lymphoblastic Leukemia,Myeloid And Lymphoid Neoplasms Associated With Pdgfra Rearrangement,Chronic Neutrophilic Leukemia,Melanoma,Chronic Eosinophilic Leukemia,Leukemia, Chronic Myeloid,B-Lymphoblastic Leukemia/Lymphoma,B-Lymphoblastic Leukemia/Lymphoma With Bcr-Abl1,B-Lymphoblastic Leukemia/Lymphoma With Hypodiploidy,B-Lymphoblastic Leukemia/Lymphoma, Bcr-Abl1-Like,B-Lymphoblastic Leukemia/Lymphoma With Iamp21,Lung Large Cell Carcinoma,Blood Platelet Disease,Essential Thrombocythemia,Myeloproliferative Neoplasm,Testicular Leukemia,Philadelphia-Negative Chronic Myeloid Leukemia,Leukemia,Mixed Phenotype Acute Leukemia,Myelophthisic Anemia,Blood Coagulation Disease,Hypereosinophilic Syndrome,Childhood Leukemia,Leukemia, Acute Myeloid,Bone Marrow Cancer,Myelodysplastic/Myeloproliferative Neoplasm,Hematologic Cancer,Leukemia, Acute Lymphoblastic,Moyamoya Angiopathy,Polycythemia,Leiomyomatosis,Central Nervous System Leukemia,Precursor T-Cell Acute Lymphoblastic Leukemia,Acquired Polycythemia,T-Cell Prolymphocytic Leukemia,Chronic Leukemia,Cockayne Syndrome,Prolymphocytic Leukemia,Lip And Oral Cavity Cancer,Ovarian Cancer,Myeloid Leukemia,T-Cell Acute Lymphoblastic Leukemia,Adult Acute Lymphocytic Leukemia,Breast Cancer,Colorectal Cancer,Congenital Heart Defects And Skeletal Malformations Syndrome,Deficiency Anemia,Leukemia, Acute Lymphoblastic 3,Retinoblastoma,Mental Retardation, Autosomal Dominant 29,Myelodysplastic Syndrome,Mental Retardation, Autosomal Dominant 33,Gastrointestinal Stromal Tumor,Lymphoblastic Leukemia, Acute, With Lymphomatous Features,Wilms Tumor 1,Leukemia, Chronic Lymphocytic,Dermatofibrosarcoma Protuberans,Ataxia-Telangiectasia,B-Cell Adult Acute Lymphocytic Leukemia,Atypical Chronic Myeloid Leukemia,Polycythemia Vera |
6amw_a | P00519 | ENSG00000097007 | ABL1 | 96.00 | 3.80E-05 | 4.00E-09 | 61.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YDR162C | NBP2 | SGDID:S000002569 | STAC2 |
SH3 and cysteine-rich domain-containing protein 2 (24b2/STAC2) (Src homology 3 and cysteine-rich domain-containing protein 2) |
Homo sapiens | Hypokalemic Periodic Paralysis, Type 1,Leukoencephalopathy With Vanishing White Matter,Myopathy, Congenital, Bailey-Bloch |
6b27_d | Q6ZMT1 | ENSG00000141750 | STAC2 | 95.50 | 0.00012 | 1.50E-08 | 47.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
YDR162C | NBP2 | SGDID:S000002569 | LELG_04233 |
LELG_04233 |
Lodderomyces elongisporus | 2kym_a | A5E3P5 | 95.00 | 0.00033 | 3.60E-08 | 49.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YDR162C | NBP2 | SGDID:S000002569 | CRKL |
Crk-like protein |
Homo sapiens | Double Outlet Right Ventricle,Leukemia, Chronic Myeloid,Acneiform Dermatitis,Chromosome 22q11.2 Duplication Syndrome,Leukemia, Acute Lymphoblastic,Cerebral Dysgenesis, Neuropathy, Ichthyosis, And Palmoplantar Keratoderma Syndrome,Sarcoma,Papillary Thyroid Microcarcinoma,Chromosome 22q11.2 Deletion Syndrome, Distal,Tetralogy Of Fallot,Digeorge Syndrome,Velocardiofacial Syndrome,Acute Promyelocytic Leukemia,Myasthenic Syndrome, Congenital, 19,Chromosomal Deletion Syndrome,Van Den Ende-Gupta Syndrome |
2lqn_a | P46109 | ENSG00000099942 | CRKL | 95.90 | 4.50E-05 | 5.10E-09 | 61.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
YDR162C | NBP2 | SGDID:S000002569 | NCF1 NOXO2 SH3PXD1A |
Neutrophil cytosol factor 1 (NCF-1) (47 kDa autosomal chronic granulomatous disease protein) (47 kDa neutrophil oxidase factor) (NCF-47K) (Neutrophil NADPH oxidase factor 1) (Nox organizer 2) (Nox-organizing protein 2) (SH3 and PX domain-containing protein 1A) (p47-phox) |
Homo sapiens | Ectodermal Dysplasia,Suppurative Lymphadenitis,Cardiomyopathy, Familial Hypertrophic, 4,Phagocyte Bactericidal Dysfunction,Chronic Granulomatous Disease,Retinitis Pigmentosa 47,Granulomatous Disease, Chronic, Autosomal Recessive, 4,Granulomatous Disease, Chronic, Autosomal Recessive, 1,Granulomatous Disease, Chronic, Autosomal Recessive, 3,Hypertension, Essential,Granulomatous Disease, Chronic, X-Linked,Lung Abscess |
1ng2_a | P14598 | ENSG00000158517 | NCF1 | 95.60 | 0.00011 | 1.20E-08 | 56.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |