YDR280W RRP45 / SGDID:S000002688
SGD CSV
Disease Associated
Homo Sapiens
Mus Musculus
Danio Rerio
Drosophila Melanogaster
Caenorhabditis Elegans
Arabidopsis Thaliana
Escherichia Coli
Yeast Systematic Name Yeast Symbol SGDID Analog Name Analog Description EC Organism Disease Structure Uniprot Human ID Human Symbol HHsearch Probability HHsearch E_value HHsearch P_value HHsearch Score Flag Disease related Flag Homo sapiens Flag Mus musculus Flag Danio rerio Flag Drosophila melanogaster Flag Caenorhabditis elegans Flag Arabidopsis thaliana Flag Escherichia coli
YDR280W RRP45 SGDID:S000002688
rrp41 AF_0493
Exosome complex component Rrp41 (EC 3.1.13.-)
 3.1.13.- Archaeoglobus fulgidus
3m7n_d O29757 100.00 4.80E-34 3.20E-38 235.80 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
rph BA_4715 GBAA_4715 BAS4377
Ribonuclease PH (RNase PH) (EC 2.7.7.56) (tRNA nucleotidyltransferase)
 2.7.7.56 Bacillus anthracis
3dd6_a Q81LA9 99.90 1.80E-32 1.20E-36 225.90 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
RRP46 YGR095C
Exosome complex component RRP46 (Ribosomal RNA-processing protein 46)
 Saccharomyces cerevisiae
5g06_d P53256 99.90 1.20E-28 8.40E-33 198.90 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
EXOSC5 CML28 RRP46
Exosome complex component RRP46 (Chronic myelogenous leukemia tumor antigen 28) (Exosome component 5) (Ribosomal RNA-processing protein 46) (p12B)
 Homo sapiens
X-Linked Nephrolithiasis Type I,Bartonellosis,Cat-Scratch Disease
 2nn6_d Q9NQT4 ENSG00000077348 EXOSC5 99.90 7.70E-33 5.10E-37 225.80 1 1 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
rrp41 MTH_683
Exosome complex component Rrp41 (EC 3.1.13.-)
 3.1.13.- Methanothermobacter thermautotrophicus
2wnr_b O26779 99.90 2.00E-33 1.40E-37 229.80 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
pnp
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)
 2.7.7.8 Streptomyces antibioticus
1e3p_a Q53597 99.90 3.00E-30 2.00E-34 242.40 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
MTR3 YGR158C G6676
Exosome complex component MTR3 (mRNA transport regulator 3)
 Saccharomyces cerevisiae
5jea_f P48240 99.80 5.60E-25 3.70E-29 179.20 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
pnp CC_0034
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)
 2.7.7.8 Caulobacter vibrioides
4aid_b Q9AC32 99.90 8.30E-31 5.50E-35 245.30 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
pnp ABSDF3154
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)
 2.7.7.8 Acinetobacter baumannii
6d6k_a B0VLR7 99.90 4.50E-32 3.00E-36 253.10 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
EXOSC7 KIAA0116 RRP42
Exosome complex component RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42) (p8)
 Homo sapiens
X-Linked Nephrolithiasis Type I
 2nn6_e Q15024 ENSG00000075914 EXOSC7 100.00 1.00E-40 6.80E-45 282.70 1 1 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
rph BSU28370
Ribonuclease PH (RNase PH) (EC 2.7.7.56) (tRNA nucleotidyltransferase)
 2.7.7.56 Bacillus subtilis
1oyr_e P28619 99.90 1.50E-32 1.00E-36 225.40 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
PNPT1 PNPASE
Polyribonucleotide nucleotidyltransferase 1, mitochondrial (EC 2.7.7.8) (3'-5' RNA exonuclease OLD35) (PNPase old-35) (Polynucleotide phosphorylase 1) (PNPase 1) (Polynucleotide phosphorylase-like protein)
 2.7.7.8 Homo sapiens
Melanoma,Myopathy, Centronuclear, 1,Combined Oxidative Phosphorylation Deficiency 13,Deafness, Autosomal Recessive 70,Nonsyndromic Deafness,Optic Atrophy 3, Autosomal Dominant,Prostate Carcinoma In Situ,Autosomal Recessive Non-Syndromic Sensorineural Deafness Type Dfnb,Autosomal Recessive Nonsyndromic Deafness,Aicardi-Goutieres Syndrome,Spastic Ataxia 5,Agenesis Of Corpus Callosum, Cardiac, Ocular, And Genital Syndrome,2-Aminoadipic 2-Oxoadipic Aciduria,Combined Oxidative Phosphorylation Deficiency,Leigh Syndrome
 3u1k_c Q8TCS8 ENSG00000138035 PNPT1 99.90 6.80E-30 4.50E-34 235.80 1 1 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
EXOSC9 PMSCL1
Exosome complex component RRP45 (Autoantigen PM/Scl 1) (Exosome component 9) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75)
 Homo sapiens
Polymyositis,Pontocerebellar Hypoplasia Type 1,X-Linked Nephrolithiasis Type I,Aortic Valve Prolapse,Primary Hyperoxaluria,Amyotrophic Lateral Sclerosis 4, Juvenile,Cerebral Atrophy,Hyperoxaluria, Primary, Type Iii,Gm1-Gangliosidosis, Type I,Limited Scleroderma,Pontocerebellar Hypoplasia, Type 1d,Osteogenesis Imperfecta, Type Xii,Spinocerebellar Ataxia, Autosomal Recessive, With Axonal Neuropathy 2,Pontocerebellar Hypoplasia, Type 1b,Spherocytosis, Type 2,Pontocerebellar Hypoplasia,Hyperoxaluria, Primary, Type Ii
 2nn6_a Q06265 ENSG00000123737 EXOSC9 100.00 7.90E-47 5.20E-51 324.10 1 1 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
rrp42 PYRAB06110 PAB0421
Exosome complex component Rrp42
 Pyrococcus abyssi
2po1_b Q9V118 100.00 1.10E-40 7.60E-45 278.90 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
rph rnpH aq_924
Ribonuclease PH (RNase PH) (EC 2.7.7.56) (tRNA nucleotidyltransferase)
 2.7.7.56 Aquifex aeolicus
1udo_a O67069 99.90 6.40E-32 4.30E-36 222.80 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
pnp CBU_0852
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)
 2.7.7.8 Coxiella burnetii
4nbq_b Q83D87 99.90 7.10E-31 4.70E-35 245.20 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
rph rphA Rv1340 MTCY02B10.04 MTCY130.25
Ribonuclease PH (RNase PH) (EC 2.7.7.56) (tRNA nucleotidyltransferase)
 2.7.7.56 Mycobacterium tuberculosis
3b4t_a P9WGZ7 100.00 7.20E-34 4.80E-38 235.40 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
rrp42 SSO0732 C20_023
Exosome complex component Rrp42
 Saccharolobus solfataricus
2je6_a Q9UXC0 100.00 5.40E-40 3.60E-44 274.80 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
rrp42 AF_0494
Exosome complex component Rrp42
 Archaeoglobus fulgidus
3m7n_g O29756 100.00 2.20E-40 1.50E-44 274.60 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
EXOSC6 MTR3
Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog) (hMtr3) (p11)
 Homo sapiens
X-Linked Nephrolithiasis Type I,Plantar Wart
 2nn6_f Q5RKV6 ENSG00000223496 EXOSC6 100.00 6.20E-35 4.20E-39 243.20 1 1 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
rph PA5334
Ribonuclease PH (RNase PH) (EC 2.7.7.56) (tRNA nucleotidyltransferase)
 2.7.7.56 Pseudomonas aeruginosa
1r6l_a P50597 99.90 2.00E-32 1.30E-36 223.80 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
EXOSC4 RRP41 SKI6
Exosome complex component RRP41 (Exosome component 4) (Ribosomal RNA-processing protein 41) (p12A)
 Homo sapiens
Lipodystrophy, Familial Partial, Type 3,Maturity-Onset Diabetes Of The Young
 2nn6_b Q9NPD3 ENSG00000178896 EXOSC4 100.00 8.60E-35 5.70E-39 239.30 1 1 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
rrp42 MTH_682
Exosome complex component Rrp42
 Methanothermobacter thermautotrophicus
2wnr_a O26778 100.00 1.90E-39 1.30E-43 270.60 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
pnp pnpA SAOUHSC_01251
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)
 2.7.7.8 Staphylococcus aureus
5xex_c Q2FZ20 99.90 2.60E-30 1.80E-34 235.30 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
SKI6 ECM20 RRP41 YGR195W G7587
Exosome complex component SKI6 (Extracellular mutant protein 20) (Ribosomal RNA-processing protein 41) (Superkiller protein 6)
 Saccharomyces cerevisiae
5c0w_b P46948 99.90 1.10E-32 7.30E-37 226.50 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
EXOSC8 OIP2 RRP43
Exosome complex component RRP43 (Exosome component 8) (Opa-interacting protein 2) (OIP-2) (Ribosomal RNA-processing protein 43) (p9)
 Homo sapiens
Cerebellar Hypoplasia,Retinitis Pigmentosa,Motor Neuron Disease,Pontocerebellar Hypoplasia Type 1,Muscular Atrophy,X-Linked Nephrolithiasis Type I,Aortic Valve Prolapse,Hyperoxaluria, Primary, Type Iii,Gm1-Gangliosidosis, Type I,Pontocerebellar Hypoplasia, Type 1c,Pontocerebellar Hypoplasia, Type 1b,Pontocerebellar Hypoplasia,Hyperoxaluria, Primary, Type Ii
 2nn6_c Q96B26 ENSG00000120699 EXOSC8 100.00 5.70E-41 3.80E-45 281.00 1 1 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
pnp EcE24377A_3647
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)
 2.7.7.8 Escherichia coli
3gme_a A7ZS61 99.90 3.20E-30 2.10E-34 234.10 0 0 0 0 0 0 0 1
YDR280W RRP45 SGDID:S000002688
RRP42 YDL111C
Exosome complex component RRP42 (Ribosomal RNA-processing protein 42)
 Saccharomyces cerevisiae
4ifd_e Q12277 100.00 4.20E-35 2.80E-39 243.60 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
rrp41 PYRAB06100 PAB0420
Exosome complex component Rrp41 (EC 3.1.13.-)
 3.1.13.- Pyrococcus abyssi
2po1_a Q9V119 100.00 3.50E-34 2.30E-38 235.60 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
RRP43 YCR035C YCR35C YCR522
Exosome complex component RRP43 (Ribosomal RNA-processing protein 43)
 Saccharomyces cerevisiae
5jea_c P25359 100.00 4.40E-36 2.90E-40 258.30 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
RRP46 Os03g0854200 LOC_Os03g63720
Exosome complex exonuclease RRP46 homolog (EC 3.1.13.-) (Exosome component 5) (Ribosomal RNA-processing protein 46) (oRrp46)
 3.1.13.- Oryza sativa
3hkm_a Q84T68 99.90 2.40E-32 1.60E-36 223.90 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
RRP45 YDR280W D9954.1
Exosome complex component RRP45 (Ribosomal RNA-processing protein 45)
 Saccharomyces cerevisiae
5g06_a Q05636 100.00 2.60E-47 1.70E-51 323.20 0 0 0 0 0 0 0 0
YDR280W RRP45 SGDID:S000002688
rrp41 SSO0735
Exosome complex component Rrp41 (EC 3.1.13.-)
 3.1.13.- Saccharolobus solfataricus
2c39_r Q9UXC2 100.00 1.20E-34 8.30E-39 238.20 0 0 0 0 0 0 0 0