| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YDR313C | PIB1 | SGDID:S000002721 | RFFL RNF189 RNF34L |
E3 ubiquitin-protein ligase rififylin (EC 2.3.2.27) (Caspase regulator CARP2) (Caspases-8 and -10-associated RING finger protein 2) (CARP-2) (FYVE-RING finger protein Sakura) (Fring) (RING finger and FYVE-like domain-containing protein 1) (RING finger protein 189) (RING finger protein 34-like) (RING-type E3 ubiquitin transferase rififylin) |
2.3.2.27 | Homo sapiens | 1y02_a | Q8WZ73 | 97.50 | 8.60E-08 | 8.10E-12 | 73.40 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YDR313C | PIB1 | SGDID:S000002721 | FGD5 ZFYVE23 |
FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23) |
Homo sapiens | Gastroduodenitis,Aarskog-Scott Syndrome |
3mpx_a | Q6ZNL6 | ENSG00000154783 | FGD5 | 97.30 | 2.00E-07 | 2.10E-11 | 82.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YDR313C | PIB1 | SGDID:S000002721 | EEA1 ZFYVE2 |
Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2) |
Homo sapiens | Charcot-Marie-Tooth Disease, Demyelinating, Type 1c,Subacute Cutaneous Lupus Erythematosus,Amyotrophic Lateral Sclerosis 1,Parkinson Disease, Late-Onset,Cataract 8, Multiple Types,Hermansky-Pudlak Syndrome,Human Monocytic Ehrlichiosis,Leukodystrophy, Hypomyelinating, 12,Charcot-Marie-Tooth Disease, Axonal, Type 2e |
1hyi_a | Q15075 | ENSG00000102189 | EEA1 | 98.10 | 1.30E-09 | 1.40E-13 | 71.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YDR313C | PIB1 | SGDID:S000002721 | RUFY1 RABIP4 ZFYVE12 |
RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (La-binding protein 1) (Rab4-interacting protein) (Zinc finger FYVE domain-containing protein 12) |
Homo sapiens | Gerstmann Syndrome |
2yqm_a | Q96T51 | ENSG00000176783 | RUFY1 | 97.80 | 1.10E-08 | 1.00E-12 | 73.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YDR313C | PIB1 | SGDID:S000002721 | ZFYVE16 KIAA0305 |
Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein) |
Homo sapiens | Dextrocardia,Arteriovenous Malformations Of The Brain,Psoriasis 14, Pustular,Aarskog-Scott Syndrome,Gluten Allergy |
3t7l_a | Q7Z3T8 | ENSG00000039319 | ZFYVE16 | 98.00 | 2.60E-09 | 2.50E-13 | 77.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YDR313C | PIB1 | SGDID:S000002721 | ZFYVE27 SPG33 |
Protrudin (Spastic paraplegia 33 protein) (Zinc finger FYVE domain-containing protein 27) |
Homo sapiens | Paraplegia,Spinal Cord Neuroblastoma,Spinal Cord Primitive Neuroectodermal Neoplasm,Spastic Paraplegia 17, Autosomal Dominant,Spastic Paraplegia 15, Autosomal Recessive,Hereditary Spastic Paraplegia,Spastic Paraplegia 44, Autosomal Recessive,Spastic Paraplegia 8, Autosomal Dominant,Spastic Paraplegia 33, Autosomal Dominant,Spastic Paraplegia 31, Autosomal Dominant,Spastic Paraplegia 10, Autosomal Dominant,Spastic Paraplegia 12, Autosomal Dominant,Spastic Paraplegia 4, Autosomal Dominant,Masa Syndrome,Mast Syndrome,Autosomal Recessive Non-Syndromic Intellectual Disability,Spastic Paraplegia 2, X-Linked,Spastic Paraplegia 6, Autosomal Dominant,Charcot-Marie-Tooth Disease, Axonal, Type 2b |
1x4u_a | Q5T4F4 | ENSG00000155256 | ZFYVE27 | 97.90 | 3.50E-09 | 3.50E-13 | 74.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YDR313C | PIB1 | SGDID:S000002721 | HGS HRS |
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110) |
Homo sapiens | Neurofibromatosis, Type Ii,Spinal Cord Primitive Neuroectodermal Neoplasm,Human T-Cell Leukemia Virus Type 2,Charcot-Marie-Tooth Disease,Hypertonia,Neuropathy, Congenital Hypomyelinating, 1, Autosomal Recessive |
3zyq_a | O14964 | ENSG00000185359 | HGS | 97.40 | 1.40E-07 | 1.40E-11 | 78.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |