| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YFR004W | RPN11 | SGDID:S000001900 | DSY2949 |
DSY2949 |
Desulfitobacterium hafniense | 2kks_a | Q24TA4 | 99.40 | 3.80E-17 | 2.80E-21 | 126.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YFR004W | RPN11 | SGDID:S000001900 | BRCC3 BRCC36 EAG_15736 |
Lys-63-specific deubiquitinase BRCC36 (EC 3.4.19.-) |
3.4.19.- | Camponotus floridanus | 5cw3_a | E2AXC7 | 99.80 | 5.10E-25 | 3.70E-29 | 187.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YFR004W | RPN11 | SGDID:S000001900 | PSMD7 MOV34L |
26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Mov34 protein homolog) (Proteasome subunit p40) |
Homo sapiens | Cystic Fibrosis,Autosomal Dominant Cerebellar Ataxia |
2o95_b | P51665 | ENSG00000103035 | PSMD7 | 99.70 | 5.30E-23 | 3.80E-27 | 166.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YFR004W | RPN11 | SGDID:S000001900 | AF_2198 |
MPN domain-containing protein |
Archaeoglobus fulgidus | 1oi0_a | O28085 | 99.30 | 2.80E-16 | 1.90E-20 | 116.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YFR004W | RPN11 | SGDID:S000001900 | sst2 SPAC19B12.10 |
AMSH-like protease sst2 (EC 3.4.19.-) (Suppressor of ste12 deletion protein 2) |
3.4.19.- | Schizosaccharomyces pombe | 4jxe_b | Q9P371 | 99.30 | 1.20E-16 | 8.20E-21 | 130.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YFR004W | RPN11 | SGDID:S000001900 | RPN11 MPR1 YFR004W |
Ubiquitin carboxyl-terminal hydrolase RPN11 (EC 3.4.19.12) (26S proteasome regulatory subunit RPN11) (Protein MPR1) |
3.4.19.12 | Saccharomyces cerevisiae | 5w83_b | P43588 | 100.00 | 5.30E-35 | 3.80E-39 | 244.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YFR004W | RPN11 | SGDID:S000001900 | COPS5 CSN5 JAB1 |
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1) |
3.4.-.- | Homo sapiens | Retinitis Pigmentosa,Maxillary Sinus Adenocarcinoma,Machado-Joseph Disease,Cerebellar Disease,Cockayne Syndrome,Hepatocellular Carcinoma,Autosomal Dominant Cerebellar Ataxia,Xeroderma Pigmentosum, Complementation Group E,Pancreatic Cancer |
4wsn_k | Q92905 | ENSG00000121022 | COPS5 | 100.00 | 1.50E-34 | 1.10E-38 | 254.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YFR004W | RPN11 | SGDID:S000001900 | PSMD14 POH1 |
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (26S proteasome-associated PAD1 homolog 1) |
3.4.19.- | Homo sapiens | Angelman Syndrome,Cystic Fibrosis,Autosomal Dominant Cerebellar Ataxia |
5vhh_c | O00487 | ENSG00000115233 | PSMD14 | 100.00 | 3.90E-49 | 2.80E-53 | 343.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YFR004W | RPN11 | SGDID:S000001900 | SRU_2040 |
SRU_2040 |
Salinibacter ruber | 2kcq_a | Q2S0Y5 | 99.30 | 1.90E-16 | 1.30E-20 | 123.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YFR004W | RPN11 | SGDID:S000001900 | CSUB_C1473 HGMM_F04B03C04 HGMM_F21D07C20 HGMM_F30C12C32 |
CSUB_C1473 HGMM_F04B03C04 HGMM_F21D07C20 HGMM_F30C12C32 |
Caldiarchaeum subterraneum | 6fjv_a | E6N8B9 | 99.50 | 1.90E-18 | 1.40E-22 | 134.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YFR004W | RPN11 | SGDID:S000001900 | RPN8 YOR261C O5360 |
26S proteasome regulatory subunit RPN8 |
Saccharomyces cerevisiae | 4o8y_a | Q08723 | 99.70 | 5.20E-22 | 3.70E-26 | 160.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YFR004W | RPN11 | SGDID:S000001900 | Lys-63-specific deubiquitinase (EC 3.4.19.-) |
Lys-63-specific deubiquitinase (EC 3.4.19.-) |
Danio rerio | 5cw6_a | A0A0M3KL72 | 99.70 | 1.40E-22 | 1.00E-26 | 172.90 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | ||||
| YFR004W | RPN11 | SGDID:S000001900 | CSN6 CG6932 |
COP9 signalosome complex subunit 6 (Dch6) (Signalosome subunit 6) |
Drosophila melanogaster | 4e0q_a | Q9VCY3 | 99.70 | 6.00E-21 | 4.30E-25 | 147.30 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | ||||
| YFR004W | RPN11 | SGDID:S000001900 | Brcc3 Brcc36 C6.1a |
Lys-63-specific deubiquitinase BRCC36 (EC 3.4.19.-) (BRCA1-A complex subunit BRCC36) (BRCA1/BRCA2-containing complex subunit 3) (BRCA1/BRCA2-containing complex subunit 36) (BRISC complex subunit BRCC36) |
3.4.19.- | Mus musculus | 6gvw_g | P46737 | 99.70 | 4.90E-22 | 3.50E-26 | 172.40 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
| YFR004W | RPN11 | SGDID:S000001900 | STAMBPL1 AMSHLP KIAA1373 |
AMSH-like protease (AMSH-LP) (EC 3.4.19.-) (STAM-binding protein-like 1) |
3.4.19.- | Homo sapiens | Autosomal Dominant Cerebellar Ataxia,Hermansky-Pudlak Syndrome 3 |
2znr_a | Q96FJ0 | ENSG00000138134 | STAMBPL1 | 99.40 | 1.40E-17 | 1.00E-21 | 133.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YFR004W | RPN11 | SGDID:S000001900 | STAMBP AMSH |
STAM-binding protein (EC 3.4.19.-) (Associated molecule with the SH3 domain of STAM) (Endosome-associated ubiquitin isopeptidase) |
3.4.19.- | Homo sapiens | Epilepsy,Microcephaly,Focal Segmental Glomerulosclerosis 1,Microcephaly-Capillary Malformation Syndrome,Acrofacial Dysostosis 1, Nager Type |
3rzu_c | O95630 | ENSG00000124356 | STAMBP | 99.40 | 4.80E-17 | 3.50E-21 | 131.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YFR004W | RPN11 | SGDID:S000001900 | COPS6 CSN6 HVIP |
COP9 signalosome complex subunit 6 (SGN6) (Signalosome subunit 6) (JAB1-containing signalosome subunit 6) (MOV34 homolog) (Vpr-interacting protein) (hVIP) |
Homo sapiens | Cockayne Syndrome,Xeroderma Pigmentosum, Complementation Group E |
4qft_a | Q7L5N1 | ENSG00000168090 | COPS6 | 99.80 | 5.30E-24 | 3.80E-28 | 172.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YFR004W | RPN11 | SGDID:S000001900 | EIF3H EIF3S3 |
EIF3H EIF3S3 |
Oryctolagus cuniculus | 5a5t_h | G1ST95 | 99.90 | 3.30E-28 | 2.30E-32 | 216.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |