| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YFR005C | SAD1 | SGDID:S000001901 | USP9X DFFRX FAM USP9 |
Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X) |
3.4.19.12 | Homo sapiens | Brain Cancer,Microcephaly,Alacrima, Achalasia, And Mental Retardation Syndrome,Turner Syndrome,Disease Of Mental Health,Developmental And Epileptic Encephalopathy 2,Mental Retardation, X-Linked 99,Mental Retardation, X-Linked 101,Mental Retardation, X-Linked 99, Syndromic, Female-Restricted,Non-Syndromic X-Linked Intellectual Disability |
5wch_a | Q93008 | ENSG00000124486 | USP9X | 100.00 | 5.10E-36 | 3.20E-40 | 282.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YFR005C | SAD1 | SGDID:S000001901 | USP2 UBP41 |
Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) |
3.4.19.12 | Homo sapiens | Fasciitis,Machado-Joseph Disease,Ovarian Serous Cystadenocarcinoma,Serous Cystadenocarcinoma,Liddle Syndrome 1 |
3nhe_a | O75604 | ENSG00000036672 | USP2 | 100.00 | 2.40E-35 | 1.50E-39 | 270.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YFR005C | SAD1 | SGDID:S000001901 | USP15 KIAA0529 |
Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Unph-2) (Unph4) |
3.4.19.12 | Homo sapiens | Breast Cancer |
6cpm_c | Q9Y4E8 | ENSG00000135655 | USP15 | 100.00 | 2.70E-36 | 1.70E-40 | 276.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YFR005C | SAD1 | SGDID:S000001901 | USP39 CGI-21 HSPC332 PRO2855 |
U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog) (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) |
Homo sapiens | 6qw6_u | Q53GS9 | ENSG00000168883 | USP39 | 100.00 | 1.90E-67 | 1.20E-71 | 510.70 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| YFR005C | SAD1 | SGDID:S000001901 | USP7 HAUSP |
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) |
3.4.19.12 | Homo sapiens | Brain Cancer,Cockayne Syndrome,Autosomal Dominant Cerebellar Ataxia,Xeroderma Pigmentosum, Variant Type,Schaaf-Yang Syndrome,Prader-Willi Syndrome,Prostate Cancer,Uv-Sensitive Syndrome,Hao-Fountain Syndrome |
1nbf_a | Q93009 | 100.00 | 7.80E-48 | 5.00E-52 | 352.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| YFR005C | SAD1 | SGDID:S000001901 | USP21 USP23 PP1490 |
Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.4.19.12) (Deubiquitinating enzyme 21) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) |
3.4.19.12 | Homo sapiens | 2y5b_e | Q9UK80 | ENSG00000143258 | USP21 | 100.00 | 1.10E-35 | 7.10E-40 | 275.10 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YFR005C | SAD1 | SGDID:S000001901 | USP14 TGT |
Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.4.19.12) (Deubiquitinating enzyme 14) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) |
3.4.19.12 | Homo sapiens | Ovarian Serous Cystadenocarcinoma,Autosomal Dominant Cerebellar Ataxia,Myeloma, Multiple |
2ayo_a | P54578 | ENSG00000101557 | USP14 | 100.00 | 1.30E-35 | 8.10E-40 | 278.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YFR005C | SAD1 | SGDID:S000001901 | USP35 KIAA1372 USP34 |
Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.4.19.12) (Deubiquitinating enzyme 35) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) |
3.4.19.12 | Homo sapiens | Juvenile-Onset Parkinson'S Disease |
5txk_a | Q9P2H5 | ENSG00000118369 | USP35 | 100.00 | 1.30E-36 | 8.40E-41 | 281.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YFR005C | SAD1 | SGDID:S000001901 | UBP6 YFR010W |
Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.4.19.12) (Deubiquitinating enzyme 6) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) |
3.4.19.12 | Saccharomyces cerevisiae | 5a5b_8 | P43593 | 100.00 | 3.00E-36 | 1.90E-40 | 283.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YFR005C | SAD1 | SGDID:S000001901 | USP7 HAUSP |
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) |
3.4.19.12 | Homo sapiens | Brain Cancer,Cockayne Syndrome,Autosomal Dominant Cerebellar Ataxia,Xeroderma Pigmentosum, Variant Type,Schaaf-Yang Syndrome,Prader-Willi Syndrome,Prostate Cancer,Uv-Sensitive Syndrome,Hao-Fountain Syndrome |
5j7t_a | Q93009 | ENSG00000187555 | USP7 | 100.00 | 1.90E-38 | 1.20E-42 | 315.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YFR005C | SAD1 | SGDID:S000001901 | USP8 KIAA0055 UBPY |
Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (hUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) |
3.4.19.12 | Homo sapiens | Autosomal Recessive Spastic Paraplegia Type 59,Adenoma,Adrenal Gland Disease,Acth-Secreting Pituitary Adenoma,Motor Neuron Disease,Pituitary Adenoma 4, Acth-Secreting,Hereditary Spastic Paraplegia,Aip Familial Isolated Pituitary Adenomas,Nelson Syndrome,Carney Complex Variant,Pituitary Gland Disease,Acth-Dependent Cushing Syndrome,Functioning Pituitary Adenoma,Pituitary Adenoma 5, Multiple Types,Pituitary Adenoma 3, Multiple Types,Prader-Willi Syndrome,Pituitary Adenoma,Multiple Endocrine Neoplasia, Type Iv,Pituitary-Dependent Cushing'S Disease,Lung Cancer |
2gfo_a | P40818 | ENSG00000138592 | USP8 | 100.00 | 1.50E-39 | 9.20E-44 | 304.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YFR005C | SAD1 | SGDID:S000001901 | USP30 |
Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.4.19.12) (Deubiquitinating enzyme 30) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Ub-specific protease 30) |
3.4.19.12 | Homo sapiens | Zellweger Syndrome,Optic Atrophy 1,Scapuloperoneal Spinal Muscular Atrophy,Juvenile-Onset Parkinson'S Disease,3-Methylglutaconic Aciduria, Type Iii |
5ohk_a | Q70CQ3 | ENSG00000135093 | USP30 | 100.00 | 2.70E-36 | 1.70E-40 | 275.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YFR005C | SAD1 | SGDID:S000001901 | USP12 UBH1 USP12L1 |
Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.4.19.12) (Deubiquitinating enzyme 12) (Ubiquitin thioesterase 12) (Ubiquitin-hydrolyzing enzyme 1) (Ubiquitin-specific-processing protease 12) |
3.4.19.12 | Homo sapiens | Tracheal Cancer |
5k16_b | O75317 | ENSG00000152484 | USP12 | 100.00 | 1.90E-35 | 1.20E-39 | 272.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YFR005C | SAD1 | SGDID:S000001901 | Usp18 Ubp43 |
Ubl carboxyl-terminal hydrolase 18 (EC 3.4.19.-) (43 kDa ISG15-specific protease) (ISG15-specific-processing protease) (Ubl thioesterase 18) |
3.4.19.- | Mus musculus | 5cht_a | Q9WTV6 | 100.00 | 9.60E-36 | 6.10E-40 | 270.60 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
| YFR005C | SAD1 | SGDID:S000001901 | USP46 |
Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.4.19.12) (Deubiquitinating enzyme 46) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) |
3.4.19.12 | Homo sapiens | Tracheal Cancer |
5l8h_a | P62068 | ENSG00000109189 | USP46 | 100.00 | 1.30E-35 | 8.00E-40 | 273.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YFR005C | SAD1 | SGDID:S000001901 | USP25 USP21 |
Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.4.19.12) (Deubiquitinating enzyme 25) (USP on chromosome 21) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) |
3.4.19.12 | Homo sapiens | Arthrogryposis, Renal Dysfunction, And Cholestasis 2,Arthrogryposis, Renal Dysfunction, And Cholestasis 1 |
6hel_b | Q9UHP3 | ENSG00000155313 | USP25 | 100.00 | 7.20E-37 | 4.50E-41 | 298.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YFR005C | SAD1 | SGDID:S000001901 | UBP8 YMR223W YM9959.05 |
Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) |
3.4.19.12 | Saccharomyces cerevisiae | 3mhs_a | P50102 | 100.00 | 2.60E-55 | 1.70E-59 | 421.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YFR005C | SAD1 | SGDID:S000001901 | USP28 KIAA1515 |
Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.4.19.12) (Deubiquitinating enzyme 28) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) |
3.4.19.12 | Homo sapiens | Colorectal Cancer |
6hei_a | Q96RU2 | ENSG00000048028 | USP28 | 100.00 | 6.00E-37 | 3.80E-41 | 285.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YFR005C | SAD1 | SGDID:S000001901 | SAD1 YFR005C |
Pre-mRNA-splicing factor SAD1 (snRNP assembly-defective protein 1) |
Saccharomyces cerevisiae | 4msx_a | P43589 | 100.00 | 1.30E-71 | 8.20E-76 | 532.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |