YFR038W IRC5 / SGDID:S000001934
SGD CSV
Disease Associated
Homo Sapiens
Mus Musculus
Danio Rerio
Drosophila Melanogaster
Caenorhabditis Elegans
Arabidopsis Thaliana
Escherichia Coli
Yeast Systematic Name Yeast Symbol SGDID Analog Name Analog Description EC Organism Disease Structure Uniprot Human ID Human Symbol HHsearch Probability HHsearch E_value HHsearch P_value HHsearch Score Flag Disease related Flag Homo sapiens Flag Mus musculus Flag Danio rerio Flag Drosophila melanogaster Flag Caenorhabditis elegans Flag Arabidopsis thaliana Flag Escherichia coli
YFR038W IRC5 SGDID:S000001934
ERCC3 XPB XPBC
General transcription and DNA repair factor IIH helicase subunit XPB (TFIIH subunit XPB) (EC 3.6.4.12) (Basic transcription factor 2 89 kDa subunit) (BTF2 p89) (DNA excision repair protein ERCC-3) (DNA repair protein complementing XP-B cells) (TFIIH basal transcription factor complex 89 kDa subunit) (TFIIH 89 kDa subunit) (TFIIH p89) (Xeroderma pigmentosum group B-complementing protein)
 3.6.4.12 Homo sapiens
Cerebro-Oculo-Facio-Skeletal Syndrome,Ichthyosis,Retinitis Pigmentosa,Hair Disease,Robinow Syndrome, Autosomal Recessive 1,Cockayne Syndrome A,Xeroderma Pigmentosum-Cockayne Syndrome Complex,Xeroderma Pigmentosum Group E,Trichothiodystrophy 1, Photosensitive,Cockayne Syndrome,Trichothiodystrophy,Breast Cancer,Xeroderma Pigmentosum, Complementation Group C,Xeroderma Pigmentosum, Complementation Group D,Xeroderma Pigmentosum, Variant Type,Xeroderma Pigmentosum, Complementation Group F,Xeroderma Pigmentosum, Complementation Group G,Skin Carcinoma,Xeroderma Pigmentosum, Complementation Group B,Xfe Progeroid Syndrome,Autosomal Recessive Disease,Trichothiodystrophy 2, Photosensitive,Trichothiodystrophy 3, Photosensitive,Ifap Syndrome 1, With Or Without Bresheck Syndrome,Uv-Sensitive Syndrome
 5of4_a P19447 ENSG00000163161 ERCC3 99.50 9.90E-19 9.50E-23 198.90 1 1 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
DNA repair and recombination protein RAD54-like (EC 3.6.4.12)
 Danio rerio
1z3i_x Q7ZV09 99.90 1.10E-27 1.10E-31 273.80 0 0 0 1 0 0 0 0
YFR038W IRC5 SGDID:S000001934
MYCTH_2307364
MYCTH_2307364
 Myceliophthora thermophila
5jxr_a G2QFM3 99.90 2.40E-33 2.20E-37 332.50 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
DHH1 YDL160C
ATP-dependent RNA helicase DHH1 (EC 3.6.4.13) (DExD/H-box helicase 1)
 3.6.4.13 Saccharomyces cerevisiae
1s2m_a P39517 99.50 2.50E-18 2.70E-22 179.20 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
recQ b3822 JW5855
ATP-dependent DNA helicase RecQ (EC 3.6.4.12)
 3.6.4.12 Escherichia coli
1oyw_a P15043 99.50 1.00E-18 1.00E-22 194.00 0 0 0 0 0 0 0 1
YFR038W IRC5 SGDID:S000001934
MJ0669
Probable ATP-dependent RNA helicase MJ0669 (EC 3.6.4.13)
 3.6.4.13 Methanocaldococcus jannaschii
1hv8_a Q58083 99.50 5.00E-19 5.60E-23 180.10 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
RNA helicase (EC 3.6.4.13)
RNA helicase (EC 3.6.4.13)
 3.6.4.13 Gallus gallus
5jaj_a G0YYQ5 99.60 1.10E-19 1.10E-23 208.80 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
DDX6 HLR2 RCK
Probable ATP-dependent RNA helicase DDX6 (EC 3.6.4.13) (ATP-dependent RNA helicase p54) (DEAD box protein 6) (Oncogene RCK)
 3.6.4.13 Homo sapiens
Nodal Marginal Zone Lymphoma,Non-Specific Syndromic Intellectual Disability,Noonan Syndrome 3,Telecanthus,Intellectual Developmental Disorder With Impaired Language And Dysmorphic Facies
 4ct4_b P26196 ENSG00000110367 DDX6 99.50 9.10E-19 1.00E-22 179.80 1 1 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
DR_1289
DR_1289
 3.6.4.12 Deinococcus radiodurans
4q47_a Q9RUU2 99.50 2.70E-19 2.70E-23 199.70 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
vas vasa CG46283
ATP-dependent RNA helicase vasa (EC 3.6.4.13) (Antigen Mab46F11)
 3.6.4.13 Drosophila melanogaster
2db3_b P09052 99.50 9.20E-19 9.90E-23 185.90 0 0 0 0 1 0 0 0
YFR038W IRC5 SGDID:S000001934
SWR1 YDR334W D9651.6
Helicase SWR1 (EC 3.6.4.12) (Swi2/Snf2-related 1)
 3.6.4.12 Saccharomyces cerevisiae
6gej_m Q05471 99.90 1.70E-31 1.50E-35 337.30 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
RIG-I
RIG-I
 3.6.4.13 Anas platyrhynchos
4a36_a D3TI84 99.50 2.30E-19 2.50E-23 198.20 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
SNF2 GAM1 RIC1 SWI2 TYE3 YOR290C
Transcription regulatory protein SNF2 (EC 3.6.4.-) (ATP-dependent helicase SNF2) (Regulatory protein GAM1) (Regulatory protein SWI2) (SWI/SNF complex component SNF2) (Transcription factor TYE3)
 3.6.4.- Saccharomyces cerevisiae
6iy2_o P22082 99.90 1.40E-32 1.30E-36 322.80 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
SSO1653
SSO1653
 Saccharolobus solfataricus
1z63_b Q97XQ7 99.80 5.00E-25 5.20E-29 242.10 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
AF_0358
AF_0358
 3.6.4.12 Archaeoglobus fulgidus
2fwr_a O29889 99.50 1.10E-18 1.10E-22 191.10 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
EIF4A1 DDX2A EIF4A
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1)
 3.6.4.13 Homo sapiens
Ovary Sarcoma
 5zc9_a P60842 ENSG00000161960 EIF4A1 99.50 2.10E-18 2.30E-22 178.60 1 1 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
cshA GT50_10605
cshA GT50_10605
 Geobacillus stearothermophilus
5ivl_b A0A0K2H973 99.50 6.70E-19 7.20E-23 186.70 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
DBP5 RAT8 YOR046C
ATP-dependent RNA helicase DBP5 (EC 3.6.4.13) (DEAD box protein 5) (Helicase CA5/6) (Ribonucleic acid-trafficking protein 8)
 3.6.4.13 Saccharomyces cerevisiae
3pey_a P20449 99.40 4.60E-18 5.00E-22 176.10 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
Ifih1
Interferon-induced helicase C domain-containing protein 1 (EC 3.6.4.13) (Helicase with 2 CARD domains) (Helicard) (Interferon induced with helicase C domain protein 1) (Melanoma differentiation-associated protein 5) (MDA-5) (RIG-I-like receptor 2) (RLR-2)
 3.6.4.13 Mus musculus
6g19_a Q8R5F7 99.50 1.10E-18 1.10E-22 200.80 0 0 1 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
DDX3X DBX DDX3
ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (CAP-Rf) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (DBX) (Helicase-like protein 2) (HLP2)
 3.6.4.13 Homo sapiens
Hepatitis C,Hepatitis B,Venezuelan Equine Encephalitis,Encephalitis,Corpus Callosum, Agenesis Of, With Facial Anomalies And Robin Sequence,Lymphocytic Choriomeningitis,Rare Genetic Intellectual Disability,Hepatitis,Infratentorial Cancer,Ddx3x-Related Neurodevelopmental Disorder,Basal Cell Nevus Syndrome,Precursor T-Cell Acute Lymphoblastic Leukemia,Breast Cancer,Microcephaly,Hepatitis C Virus,Alacrima, Achalasia, And Mental Retardation Syndrome,Noonan Syndrome 3,Disease Of Mental Health,Adult Medulloblastoma,Childhood Medulloblastoma,Intellectual Developmental Disorder, X-Linked, Syndromic, Snijders Blok Type,Ewing Sarcoma,Syndromic Intellectual Disability,Agenesis Of Corpus Callosum, Cardiac, Ocular, And Genital Syndrome,Medulloblastoma,Systemic Epstein-Barr Virus-Positive T-Cell Lymphoma Of Childhood,Cerebellar Hypoplasia/Atrophy, Epilepsy, And Global Developmental Delay
 2i4i_a O00571 ENSG00000215301 DDX3X 99.50 1.20E-18 1.30E-22 181.90 1 1 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
RAD26 GTA1085 YJR035W J1606
DNA repair and recombination protein RAD26 (EC 3.6.4.12) (ATP-dependent helicase RAD26)
 3.6.4.12 Saccharomyces cerevisiae
5vvr_m P40352 99.90 3.00E-28 2.60E-32 300.00 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
MSS116 YDR194C YD9346.05C
ATP-dependent RNA helicase MSS116, mitochondrial (EC 3.6.4.13)
 3.6.4.13 Saccharomyces cerevisiae
3i5x_a P15424 99.50 1.50E-18 1.50E-22 194.70 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
Ddx58
Antiviral innate immune response receptor RIG-I (DEAD box protein 58) (Probable ATP-dependent RNA helicase DDX58) (EC 3.6.4.13) (RIG-I-like receptor 1) (RLR-1) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)
 3.6.4.13 Mus musculus
3tbk_a Q6Q899 99.60 6.80E-21 7.20E-25 210.20 0 0 1 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
MYCTH_115909
MYCTH_115909
 Myceliophthora thermophila
5hzr_a G2QDW1 99.90 9.10E-34 8.90E-38 333.50 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
CHD1 YER164W SYGP-ORF4
Chromo domain-containing protein 1 (EC 3.6.4.-) (ATP-dependent helicase CHD1)
 3.6.4.- Saccharomyces cerevisiae
6ftx_w P32657 99.90 1.00E-27 1.00E-31 288.50 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
TIF1 TIF41A YKR059W; TIF2 TIF41B YJL138C J0660
ATP-dependent RNA helicase eIF4A (EC 3.6.4.13) (Eukaryotic initiation factor 4A) (eIF-4A) (Stimulator factor I 37 kDa component) (Translation initiation factor 1/2) (p37)
 3.6.4.13 Saccharomyces cerevisiae
1fuu_b P10081 99.50 2.60E-18 2.90E-22 178.70 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
SUB2 YDL084W
ATP-dependent RNA helicase SUB2 (EC 3.6.4.13) (Suppressor of BRR1 protein 2)
 3.6.4.13 Saccharomyces cerevisiae
5sup_b Q07478 99.50 1.90E-19 2.10E-23 186.80 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
CTHT_0026210
CTHT_0026210
 Chaetomium thermophilum
6g7e_b G0S6C0 99.80 6.20E-24 6.30E-28 271.60 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
PRP28 YDR243C YD8419.10C
Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (EC 3.6.4.13) (Helicase CA8)
 3.6.4.13 Saccharomyces cerevisiae
4w7s_a P23394 99.50 1.90E-18 2.10E-22 185.40 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
DDX23
Probable ATP-dependent RNA helicase DDX23 (EC 3.6.4.13) (100 kDa U5 snRNP-specific protein) (DEAD box protein 23) (PRP28 homolog) (U5-100kD)
 3.6.4.13 Homo sapiens
Retinitis Pigmentosa,Burn-Mckeown Syndrome,Distal Hereditary Motor Neuronopathy Type 2,Cockayne Syndrome,Spinal Muscular Atrophy, Type I
 4nho_a Q9BUQ8 ENSG00000174243 DDX23 99.50 2.20E-18 2.30E-22 186.30 1 1 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
RECQL5 RECQ5
ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5)
 3.6.4.12 Homo sapiens
Rothmund-Thomson Syndrome, Type 2,Baller-Gerold Syndrome,Werner Syndrome,Fanconi Anemia, Complementation Group A,Bloom Syndrome,Rapadilino Syndrome
 5lb3_e O94762 ENSG00000108469 RECQL5 99.50 3.80E-18 4.00E-22 182.50 1 1 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
HAS1 YMR290C
ATP-dependent RNA helicase HAS1 (EC 3.6.4.13) (Helicase associated with SET1 protein 1)
 3.6.4.13 Saccharomyces cerevisiae
5z3g_y Q03532 99.60 1.70E-19 1.80E-23 199.00 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
rapA ECS88_0062
RNA polymerase-associated protein RapA (EC 3.6.4.-) (ATP-dependent helicase HepA)
 3.6.4.- Escherichia coli
6bog_b B7MAI2 99.60 4.30E-20 4.00E-24 224.30 0 0 0 0 0 0 0 1
YFR038W IRC5 SGDID:S000001934
PRP5 RNA5 YBR237W YBR1603
Pre-mRNA-processing ATP-dependent RNA helicase PRP5 (EC 3.6.4.13)
 3.6.4.13 Saccharomyces cerevisiae
4ljy_a P21372 99.50 3.40E-19 3.50E-23 193.90 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
PF2015
PF2015
 Pyrococcus furiosus
1wp9_a Q8TZH8 99.50 2.30E-19 2.60E-23 187.80 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
BmVLG
BmVLG
 3.6.4.13 Bombyx mori
4d25_a O01378 99.50 5.30E-19 5.80E-23 187.00 0 0 0 0 0 0 0 0
YFR038W IRC5 SGDID:S000001934
RECQL RECQ1 RECQL1
ATP-dependent DNA helicase Q1 (EC 3.6.4.12) (DNA helicase, RecQ-like type 1) (RecQ1) (DNA-dependent ATPase Q1) (RecQ protein-like 1)
 3.6.4.12 Homo sapiens
Rothmund-Thomson Syndrome, Type 2,Baller-Gerold Syndrome,Inherited Cancer-Predisposing Syndrome,Ovarian Cancer,Hereditary Breast Ovarian Cancer Syndrome,Werner Syndrome,Xeroderma Pigmentosum, Complementation Group C,Xeroderma Pigmentosum, Variant Type,Fanconi Anemia, Complementation Group A,Tumor Predisposition Syndrome,Cutaneous Telangiectasia And Cancer Syndrome, Familial,Bloom Syndrome,Rapadilino Syndrome
 2v1x_b P46063 ENSG00000004700 RECQL 99.50 5.30E-19 5.10E-23 202.70 1 1 0 0 0 0 0 0