| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YGL009C | LEU1 | SGDID:S000002977 | leuC MJ0499 |
Isopropylmalate/citramalate isomerase large subunit (EC 4.2.1.33) (EC 4.2.1.35) ((R)-2-methylmalate dehydratase) ((R)-citramalate dehydratase) (3-isopropylmalate dehydratase) (Alpha-isopropylmalate dehydratase) (Citraconate hydratase) (Isopropylmalate isomerase) (IPMI) (Maleate hydratase) (Malease) (EC 4.2.1.31) |
4.2.1.31,4.2.1.33,4.2.1.35 | Methanocaldococcus jannaschii | 4kp1_a | P81291 | 100.00 | 1.70E-97 | 1.00E-101 | 830.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGL009C | LEU1 | SGDID:S000002977 | ACO1 IREB1 |
Cytoplasmic aconitate hydratase (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) (Ferritin repressor protein) (Iron regulatory protein 1) (IRP1) (Iron-responsive element-binding protein 1) (IRE-BP 1) |
4.2.1.3 | Homo sapiens | Sideroblastic Anemia,Metal Metabolism Disorder,Amyotrophic Lateral Sclerosis 1,Neurodegeneration With Brain Iron Accumulation,Iron Metabolism Disease,Hemochromatosis Type 2,Cataract,Ehrlichiosis,Parkinson Disease, Late-Onset,Parkinson Disease 1, Autosomal Dominant,Deficiency Anemia,Microcytic Anemia,Friedreich Ataxia,Protoporphyria, Erythropoietic, 1,Aceruloplasminemia,Hemochromatosis, Type 1,Beta-Thalassemia,Anemia, Sideroblastic, 1,Restless Legs Syndrome,Neurodegeneration With Brain Iron Accumulation 3,Hypochromic Microcytic Anemia,Anemia, Sideroblastic, And Spinocerebellar Ataxia,Spastic Paraplegia 38, Autosomal Dominant,Infantile Cerebellar-Retinal Degeneration,Hyperferritinemia With Or Without Cataract,Erythrocytosis, Familial, 2 |
2b3y_a | P21399 | ENSG00000122729 | ACO1 | 100.00 | 6.00E-129 | 5.00E-133 | 1152.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YGL009C | LEU1 | SGDID:S000002977 | ACO2 |
Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) |
4.2.1.3 | Sus scrofa | 5acn_a | P16276 | 100.00 | 3.00E-123 | 2.00E-127 | 1094.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGL009C | LEU1 | SGDID:S000002977 | hacA MJ1003 |
Methanogen homoaconitase large subunit (HACN) (EC 4.2.1.114) (Homoaconitate hydratase) |
4.2.1.114 | Methanocaldococcus jannaschii | 4kp2_b | Q58409 | 100.00 | 4.90E-89 | 3.80E-93 | 763.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGL009C | LEU1 | SGDID:S000002977 | acnB yacI yacJ b0118 JW0114 |
Aconitate hydratase B (ACN) (Aconitase) (EC 4.2.1.3) ((2R,3S)-2-methylisocitrate dehydratase) ((2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase) (2-methyl-cis-aconitate hydratase) (EC 4.2.1.99) (Iron-responsive protein-like) (IRP-like) (RNA-binding protein) |
4.2.1.3,4.2.1.99, | Escherichia coli | 1l5j_a | P36683 | 100.00 | 1.60E-86 | 1.20E-90 | 782.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
| YGL009C | LEU1 | SGDID:S000002977 | ACO2 |
Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) |
4.2.1.3 | Bos taurus | 1c96_a | P20004 | 100.00 | 4.00E-122 | 3.00E-126 | 1086.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |