| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YGL251C | HFM1 | SGDID:S000003220 | BRR2 RSS1 SNU246 YER172C SYGP-ORF66 |
Pre-mRNA-splicing helicase BRR2 (EC 3.6.4.13) (Protein Snu246) |
3.6.4.13 | Saccharomyces cerevisiae | 5dca_a | P32639 | 100.00 | 3.70E-47 | 4.30E-51 | 474.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGL251C | HFM1 | SGDID:S000003220 | BmVLG |
BmVLG |
3.6.4.13 | Bombyx mori | 4d25_a | O01378 | 99.40 | 1.00E-17 | 1.40E-21 | 165.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGL251C | HFM1 | SGDID:S000003220 | SUB2 YDL084W |
ATP-dependent RNA helicase SUB2 (EC 3.6.4.13) (Suppressor of BRR1 protein 2) |
3.6.4.13 | Saccharomyces cerevisiae | 5sup_b | Q07478 | 99.40 | 6.20E-18 | 8.90E-22 | 163.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGL251C | HFM1 | SGDID:S000003220 | PRP28 YDR243C YD8419.10C |
Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (EC 3.6.4.13) (Helicase CA8) |
3.6.4.13 | Saccharomyces cerevisiae | 4w7s_a | P23394 | 99.50 | 3.30E-19 | 4.50E-23 | 179.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGL251C | HFM1 | SGDID:S000003220 | CTHT_0063660 |
CTHT_0063660 |
Chaetomium thermophilum | 6faa_a | G0SEG4 | 99.50 | 2.70E-18 | 3.50E-22 | 184.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL251C | HFM1 | SGDID:S000003220 | EIF4A1 DDX2A EIF4A |
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1) |
3.6.4.13 | Homo sapiens | Ovary Sarcoma |
5zc9_a | P60842 | ENSG00000161960 | EIF4A1 | 99.40 | 1.20E-17 | 1.80E-21 | 161.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YGL251C | HFM1 | SGDID:S000003220 | MSS116 YDR194C YD9346.05C |
ATP-dependent RNA helicase MSS116, mitochondrial (EC 3.6.4.13) |
3.6.4.13 | Saccharomyces cerevisiae | 3i5x_a | P15424 | 99.40 | 3.60E-18 | 4.60E-22 | 181.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGL251C | HFM1 | SGDID:S000003220 | RIG-I |
RIG-I |
3.6.4.13 | Anas platyrhynchos | 4a36_a | D3TI84 | 99.40 | 1.30E-17 | 1.80E-21 | 173.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGL251C | HFM1 | SGDID:S000003220 | MTREX DOB1 KIAA0052 MTR4 SKIV2L2 |
Exosome RNA helicase MTR4 (EC 3.6.4.13) (ATP-dependent RNA helicase DOB1) (ATP-dependent RNA helicase SKIV2L2) (Superkiller viralicidic activity 2-like 2) (TRAMP-like complex helicase) |
3.6.4.13 | Homo sapiens | X-Linked Nephrolithiasis Type I,Robinow Syndrome, Autosomal Dominant 1,Robinow Syndrome |
6c90_a | P42285 | ENSG00000039123 | MTREX | 99.60 | 1.50E-19 | 1.80E-23 | 201.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YGL251C | HFM1 | SGDID:S000003220 | RECQL5 RECQ5 |
ATP-dependent DNA helicase Q5 (EC 3.6.4.12) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5) |
3.6.4.12 | Homo sapiens | Rothmund-Thomson Syndrome, Type 2,Baller-Gerold Syndrome,Werner Syndrome,Fanconi Anemia, Complementation Group A,Bloom Syndrome,Rapadilino Syndrome |
5lb3_e | O94762 | ENSG00000108469 | RECQL5 | 99.40 | 1.60E-17 | 2.10E-21 | 167.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YGL251C | HFM1 | SGDID:S000003220 | cshA GT50_10605 |
cshA GT50_10605 |
Geobacillus stearothermophilus | 5ivl_b | A0A0K2H973 | 99.40 | 4.40E-18 | 6.10E-22 | 169.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL251C | HFM1 | SGDID:S000003220 | SKI2 YLR398C L8084.17 |
Antiviral helicase SKI2 (EC 3.6.4.13) (Superkiller protein 2) |
3.6.4.13 | Saccharomyces cerevisiae | 4a4z_a | P35207 | 99.50 | 1.70E-18 | 2.00E-22 | 202.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGL251C | HFM1 | SGDID:S000003220 | hel308 hjm PF0677 |
ATP-dependent DNA helicase Hel308 (EC 3.6.4.12) (ATP-dependent Holliday junction unwindase Hjm) (Holliday junction migration DNA helicase) |
3.6.4.12 | Pyrococcus furiosus | 2zj8_a | O73946 | 99.90 | 1.20E-31 | 1.50E-35 | 295.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGL251C | HFM1 | SGDID:S000003220 | B9B11.040 frh NCU03363.1 |
B9B11.040 frh NCU03363.1 |
Neurospora crassa | 4xgt_a | Q873J5 | 99.40 | 1.20E-17 | 1.40E-21 | 193.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL251C | HFM1 | SGDID:S000003220 | DDX6 HLR2 RCK |
Probable ATP-dependent RNA helicase DDX6 (EC 3.6.4.13) (ATP-dependent RNA helicase p54) (DEAD box protein 6) (Oncogene RCK) |
3.6.4.13 | Homo sapiens | Nodal Marginal Zone Lymphoma,Non-Specific Syndromic Intellectual Disability,Noonan Syndrome 3,Telecanthus,Intellectual Developmental Disorder With Impaired Language And Dysmorphic Facies |
4ct4_b | P26196 | ENSG00000110367 | DDX6 | 99.40 | 6.10E-18 | 8.90E-22 | 161.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YGL251C | HFM1 | SGDID:S000003220 | MYCTH_115909 |
MYCTH_115909 |
Myceliophthora thermophila | 5hzr_a | G2QDW1 | 99.40 | 1.80E-17 | 2.10E-21 | 184.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL251C | HFM1 | SGDID:S000003220 | HAS1 YMR290C |
ATP-dependent RNA helicase HAS1 (EC 3.6.4.13) (Helicase associated with SET1 protein 1) |
3.6.4.13 | Saccharomyces cerevisiae | 5z3g_y | Q03532 | 99.50 | 7.20E-19 | 9.30E-23 | 183.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGL251C | HFM1 | SGDID:S000003220 | PRP5 RNA5 YBR237W YBR1603 |
Pre-mRNA-processing ATP-dependent RNA helicase PRP5 (EC 3.6.4.13) |
3.6.4.13 | Saccharomyces cerevisiae | 4ljy_a | P21372 | 99.50 | 1.50E-18 | 2.10E-22 | 177.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGL251C | HFM1 | SGDID:S000003220 | CTHT_0009470 |
CTHT_0009470 |
Chaetomium thermophilum | 5m59_a | G0S0B9 | 100.00 | 3.10E-44 | 4.00E-48 | 435.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL251C | HFM1 | SGDID:S000003220 | MTR4 DOB1 YJL050W J1158 |
ATP-dependent RNA helicase DOB1 (EC 3.6.4.13) (mRNA transport regulator MTR4) |
3.6.4.13 | Saccharomyces cerevisiae | 4u4c_a | P47047 | 99.50 | 3.00E-19 | 3.60E-23 | 206.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGL251C | HFM1 | SGDID:S000003220 | SNRPB COD SNRPB1 |
Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/B') (SmB/B') |
Homo sapiens | Burn-Mckeown Syndrome,Spinal Muscular Atrophy,Muscular Atrophy,Lupus Erythematosus,Isolated Pierre Robin Sequence,Cerebrocostomandibular Syndrome,Disease Of Mental Health,Mandibulofacial Dysostosis, Guion-Almeida Type,Otospondylomegaepiphyseal Dysplasia, Autosomal Dominant,Systemic Lupus Erythematosus,Acrofacial Dysostosis 1, Nager Type,Pierre Robin Syndrome |
6qdv_b | P14678 | ENSG00000125835 | SNRPB | 100.00 | 7.90E-45 | 1.00E-48 | 438.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YGL251C | HFM1 | SGDID:S000003220 | MSMEG_1757 |
MSMEG_1757 |
Mycolicibacterium smegmatis | 5v9x_a | A0QT91 | 99.50 | 1.20E-18 | 1.40E-22 | 201.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGL251C | HFM1 | SGDID:S000003220 | DHH1 YDL160C |
ATP-dependent RNA helicase DHH1 (EC 3.6.4.13) (DExD/H-box helicase 1) |
3.6.4.13 | Saccharomyces cerevisiae | 1s2m_a | P39517 | 99.40 | 5.00E-18 | 7.10E-22 | 165.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGL251C | HFM1 | SGDID:S000003220 | POLQ POLH |
DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta) |
2.7.7.7 | Homo sapiens | Interdigitating Dendritic Cell Sarcoma,Xeroderma Pigmentosum, Variant Type,Fanconi Anemia, Complementation Group A |
5aga_a | O75417 | ENSG00000051341 | POLQ | 99.80 | 2.50E-25 | 3.10E-29 | 251.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YGL251C | HFM1 | SGDID:S000003220 | ST2459 STK_24590 |
ST2459 STK_24590 |
3.6.4.13 | Sulfurisphaera tokodaii | 2z0m_a | Q96XQ7 | 99.40 | 1.10E-17 | 1.60E-21 | 155.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |