Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
YGL259W | YPS5 | SGDID:S000003228 | EDGP1 |
EDGP1 |
Daucus carota | 3vla_a | Q05929 | 96.80 | 1.90E-06 | 2.20E-10 | 68.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YGL259W | YPS5 | SGDID:S000003228 | PGA |
Pepsin A (EC 3.4.23.1) |
3.4.23.1 | Sus scrofa | 2psg_a | P00791 | 96.70 | 2.80E-06 | 3.40E-10 | 65.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YGL259W | YPS5 | SGDID:S000003228 | SAP2 PRA11 PRA2 |
Candidapepsin-2 (EC 3.4.23.24) (ACP 2) (Aspartate protease 2) (Secreted aspartic protease 2) |
3.4.23.24 | Candida albicans | 3pvk_a | P0CS83 | 97.00 | 7.90E-07 | 9.50E-11 | 67.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YGL259W | YPS5 | SGDID:S000003228 | PLM2 |
Plasmepsin-2 (EC 3.4.23.39) (Aspartic hemoglobinase II) (PFAPD) |
3.4.23.39 | Plasmodium falciparum | 1xdh_a | P46925 | 96.50 | 7.40E-06 | 9.00E-10 | 61.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YGL259W | YPS5 | SGDID:S000003228 | Putative cathepsin d |
Putative cathepsin d |
Ixodes ricinus | 5n7q_b | V5HCK7 | 96.60 | 4.20E-06 | 5.10E-10 | 62.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YGL259W | YPS5 | SGDID:S000003228 | CTSD CPSD |
Cathepsin D (EC 3.4.23.5) [Cleaved into: Cathepsin D light chain; Cathepsin D heavy chain] |
3.4.23.5 | Homo sapiens | Endometrial Cancer,Autosomal Dominant Polycystic Kidney Disease,Amyloidosis,Mucolipidosis,Gaucher'S Disease,Sphingolipidosis,Alzheimer Disease,Corneal Dystrophy, Subepithelial Mucinous,Amelogenesis Imperfecta,Adenosquamous Carcinoma,Mucopolysaccharidosis Iii,Mucopolysaccharidosis-Plus Syndrome,Larynx Cancer,Microlissencephaly,Rosai-Dorfman Disease,Dementia,Endometrial Clear Cell Adenocarcinoma,Colonic Disease,Mixed Cell Adenoma,Breast Cyst,Ovarian Cancer,Breast Ductal Carcinoma,Breast Cancer,Fanconi Syndrome,Parkinson Disease, Late-Onset,Colorectal Cancer,Spinocerebellar Ataxia, Autosomal Recessive 7,Ceroid Lipofuscinosis, Neuronal, 13,Human Immunodeficiency Virus Type 1,Lysosomal Storage Disease,Macular Degeneration, Age-Related, 1,Neuronal Ceroid Lipofuscinosis,Niemann-Pick Disease,Breast Adenocarcinoma,Neuronal Ceroid-Lipofuscinoses,Ceroid Lipofuscinosis, Neuronal, 10,Breast Disease,Disease Of Mental Health,Gaucher Disease, Type I,Creutzfeldt-Jakob Disease,Body Mass Index Quantitative Trait Locus 11,Breast Fibroadenoma,Dementia, Lewy Body,Ceroid Lipofuscinosis, Neuronal, 7,Hirschsprung Disease 1,Meningioma, Familial,Ductal Carcinoma In Situ,Mucolipidosis Ii Alpha/Beta,Mucolipidosis Iii Alpha/Beta,Ceroid Lipofuscinosis, Neuronal, 3,Ceroid Lipofuscinosis, Neuronal, 4a, Autosomal Recessive,Ceroid Lipofuscinosis, Neuronal, 2,C Syndrome,Ceroid Lipofuscinosis, Neuronal, 1 |
1lyb_c | P07339 | ENSG00000117984 | CTSD | 97.10 | 4.30E-07 | 5.00E-11 | 58.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YGL259W | YPS5 | SGDID:S000003228 | SAPP1 ACPR |
Candidapepsin-1 (EC 3.4.23.24) (ACP 1) (Aspartate protease 1) |
3.4.23.24 | Candida parapsilosis | 3fv3_a | P32951 | 96.80 | 2.20E-06 | 2.60E-10 | 65.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YGL259W | YPS5 | SGDID:S000003228 | cardB |
Procardosin-B (EC 3.4.23.-) [Cleaved into: Cardosin-B heavy chain (Cardosin-B 34 kDa subunit); Cardosin-B light chain (Cardosin-B 14 kDa subunit)] |
3.4.23.- | Cynara cardunculus | 5nfg_a | Q9XFX4 | 97.00 | 9.40E-07 | 1.10E-10 | 69.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YGL259W | YPS5 | SGDID:S000003228 | CARP |
Mucorpepsin (EC 3.4.23.23) (Mucor rennin) |
3.4.23.23 | Rhizomucor miehei | 2rmp_a | P00799 | 96.60 | 5.40E-06 | 6.60E-10 | 63.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YGL259W | YPS5 | SGDID:S000003228 | CTSE |
Cathepsin E (EC 3.4.23.34) [Cleaved into: Cathepsin E form I; Cathepsin E form II] |
3.4.23.34 | Homo sapiens | Gastric Tubular Adenocarcinoma,Rosai-Dorfman Disease,Gastric Papillary Adenocarcinoma,Dermatitis, Atopic,Tetanus |
1tzs_a | P14091 | ENSG00000196188 | CTSE | 96.50 | 7.80E-06 | 9.50E-10 | 61.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YGL259W | YPS5 | SGDID:S000003228 | proA |
proA |
Hypocrea jecorina | 3c9x_a | Q2WBH2 | 96.80 | 1.70E-06 | 2.10E-10 | 65.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YGL259W | YPS5 | SGDID:S000003228 | REN |
Renin (EC 3.4.23.15) (Angiotensinogenase) |
3.4.23.15 | Homo sapiens | Aortic Aneurysm, Familial Abdominal, 1,Heart Valve Disease,Tricuspid Valve Insufficiency,Mitral Valve Disease,Pulmonary Edema,Heart Disease,Severe Nonproliferative Diabetic Retinopathy,Steroid Inherited Metabolic Disorder,Autosomal Dominant Polycystic Kidney Disease,Renal Tubular Dysgenesis,Autonomic Nervous System Disease,Constrictive Pericarditis,Cardiac Tamponade,Mitral Valve Insufficiency,Diabetic Autonomic Neuropathy,Hypertensive Heart Disease,Pseudohypoparathyroidism,Mitral Valve Stenosis,Glucose Metabolism Disease,Chondrocalcinosis,Hypertensive Retinopathy,Vascular Disease,Migraine With Or Without Aura 1,Ovarian Hyperstimulation Syndrome,Aortic Valve Disease 2,Urinary System Disease,Cakut,Diabetic Macular Edema,Polycystic Kidney Disease,Central Sleep Apnea,Hyperuricemia,Overnutrition,Inherited Metabolic Disorder,Diabetes Mellitus,Adrenal Adenoma,Adenoma,Pericardial Effusion,Adult Syndrome,Hepatorenal Syndrome,Nephrotic Syndrome,Coronavirus Infectious Disease,Coronary Artery Vasospasm,Diabetes Insipidus,Cerebrovascular Disease,Familial Glucocorticoid Deficiency,Hypertensive Encephalopathy,Multicystic Dysplastic Kidney,Hyperaldosteronism, Familial, Type I,Hypertrophic Cardiomyopathy,Bartter Disease,Conn'S Syndrome,Alzheimer Disease,Renal Tubular Transport Disease,Pseudohypoaldosteronism,Adrenal Gland Disease,Hypokalemia,Myocardial Infarction,Orthostatic Proteinuria,Acute Adrenal Insufficiency,Kidney Hypertrophy,Stroke, Ischemic,Urogenital Tuberculosis,Apparent Mineralocorticoid Excess,Premenstrual Tension,Oligohydramnios,Renal Tuberculosis,Uremia,Diabetic Neuropathy,Diastolic Heart Failure,Tubulointerstitial Kidney Disease, Autosomal Dominant, 1,Gastroenteritis,Generalized Atherosclerosis,Antenatal Bartter Syndrome,Renal Artery Disease,Acute Kidney Tubular Necrosis,Apnea, Obstructive Sleep,Placenta Disease,End Stage Renal Disease,Postural Orthostatic Tachycardia Syndrome,Arteries, Anomalies Of,Chronic Kidney Disease,Potter'S Syndrome,Idiopathic Hypercalciuria,Retinal Vascular Disease,Autosomal Dominant Tubulointerstitial Kidney Disease - Ren,Rheumatoid Vasculitis,Liver Cirrhosis,Cardiovascular System Disease,Horseshoe Kidney,Kidney Hemangiopericytoma,Polycythemia,Dilated Cardiomyopathy,Hypoaldosteronism,Arteriolosclerosis,Alcoholic Cardiomyopathy,Tubulointerstitial Kidney Disease, Autosomal Dominant, 4,Aortic Disease,Urinary Tract Obstruction,Carotid Stenosis,Aortic Valve Disease 1,Hepatic Vascular Disease,Pyeloureteritis Cystica,Pyelitis,Acute Cystitis,Sleep Disorder,Acute Pulmonary Heart Disease,Type 1 Diabetes Mellitus,Acute Cor Pulmonale,Diarrhea,Left Bundle Branch Hemiblock,Heart Conduction Disease,Renal Artery Obstruction,Chronic Intestinal Failure,Kidney Disease,Kidney Papillary Necrosis,Adrenal Cortical Hypofunction,Perinephritis,Anuria,Iga Glomerulonephritis,Supine Hypotensive Syndrome,Pre-Eclampsia,Acute Kidney Failure,Arthrogryposis, Distal, Type 3,Eclampsia,Obstructive Jaundice,Intermediate Coronary Syndrome,Patent Foramen Ovale,Interstitial Nephritis,Aortic Valve Insufficiency,Malignant Renovascular Hypertension,Malignant Secondary Hypertension,Renal Hypertension,Chronic Pyelonephritis,Ectodermal Dysplasia 10b, Hypohidrotic/Hair/Tooth Type, Autosomal Recessive,Renal Dysplasia,Malignant Hypertension,Renal Artery Atheroma,Pheochromocytoma,Congestive Heart Failure,Autosomal Dominant Tubulointerstitial Kidney Disease,Benign Essential Hypertension,Congenital Chloride Diarrhea,Renal Tubular Acidosis,Ureteral Disease,Pulmonary Valve Insufficiency,Ovarian Disease,Polycystic Kidney Disease 1 With Or Without Polycystic Liver Disease,Hydronephrosis,Respiratory Failure,Parathyroid Gland Disease,Hypothyroidism,Inappropriate Adh Syndrome,Cholesterol Embolism,Carotid Artery Disease,Retinal Microaneurysm,Disease Of Mental Health,Liddle Syndrome 1,Pulmonary Hypertension,Body Mass Index Quantitative Trait Locus 11,Pseudohypoaldosteronism, Type I, Autosomal Dominant,Twin-To-Twin Transfusion Syndrome,Renovascular Hypertension,Diabetes Insipidus, Nephrogenic, Autosomal,Type 2 Diabetes Mellitus,Mineral Metabolism Disease,Orthostatic Intolerance,Adrenal Carcinoma,Adrenal Cortex Disease,Extrinsic Cardiomyopathy,Hypoadrenocorticism, Familial,Brachydactyly,Tetralogy Of Fallot,Renal Hypodysplasia/Aplasia 1,Tricuspid Valve Disease,Pericardium Disease,Sleep Apnea,Renal Fibrosis,Vesicoureteral Reflux 1,Congenital Anomalies Of Kidney And Urinary Tract 2,Adrenal Cortical Adenoma,Wilms Tumor 1,Hypertension, Essential,Intrinsic Cardiomyopathy,Sexual Disorder,Lipoprotein Quantitative Trait Locus,Cell Type Benign Neoplasm,Endocrine Organ Benign Neoplasm,Bartter Syndrome, Type 3,Patent Ductus Arteriosus 1,Acquired Metabolic Disease,Lipoid Congenital Adrenal Hyperplasia,Intracranial Berry Aneurysm,Corticosterone Methyloxidase Type I Deficiency,Cardiac Arrest,Taqi Polymorphism,Obstructive Nephropathy,Gitelman Syndrome,Pseudohypoaldosteronism, Type I, Autosomal Recessive |
3k1w_b | P00797 | ENSG00000143839 | REN | 96.60 | 4.20E-06 | 5.10E-10 | 63.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YGL259W | YPS5 | SGDID:S000003228 | SAP3 CAALFM_C305230WA CaO19.13422 CaO19.6001 |
Candidapepsin-3 (EC 3.4.23.24) (ACP 3) (Aspartate protease 3) (Secreted aspartic protease 3) |
3.4.23.24 | Candida albicans | 2h6s_a | P0CY29 | 96.60 | 5.10E-06 | 6.10E-10 | 63.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YGL259W | YPS5 | SGDID:S000003228 | BACE1 BACE KIAA1149 |
Beta-secretase 1 (EC 3.4.23.46) (Aspartyl protease 2) (ASP2) (Asp 2) (Beta-site amyloid precursor protein cleaving enzyme 1) (Beta-site APP cleaving enzyme 1) (Memapsin-2) (Membrane-associated aspartic protease 2) |
3.4.23.46 | Homo sapiens | Chromosomal Disease,Supranuclear Palsy, Progressive, 1,Amyloidosis,Alzheimer Disease,Cerebral Amyloid Angiopathy, Cst3-Related,Stroke, Ischemic,Amyotrophic Lateral Sclerosis 1,Myositis,Mild Cognitive Impairment,Neuroblastoma,Actinobacillosis,Dementia,Necatoriasis,Nervous System Disease,Vascular Dementia,Parkinson Disease, Late-Onset,Peripheral Nervous System Disease,Pick Disease Of Brain,Developmental And Epileptic Encephalopathy 5,Disease Of Mental Health,Creutzfeldt-Jakob Disease,Toxic Encephalopathy,Dementia, Lewy Body,Schizophrenia,Down Syndrome,Alzheimer Disease 4,Ischiocoxopodopatellar Syndrome With Or Without Pulmonary Arterial Hypertension,Alzheimer Disease 3,Chromosomal Duplication Syndrome |
2q15_a | P56817 | ENSG00000186318 | BACE1 | 96.50 | 5.90E-06 | 7.10E-10 | 63.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YGL259W | YPS5 | SGDID:S000003228 | PFBG_05102 |
PFBG_05102 |
Plasmodium falciparum | 5jod_b | W7FF86 | 96.70 | 3.00E-06 | 3.50E-10 | 66.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YGL259W | YPS5 | SGDID:S000003228 | Ren1 Ren |
Renin (EC 3.4.23.15) (Angiotensinogenase) |
3.4.23.15 | Rattus norvegicus | 5mlg_a | P08424 | 96.90 | 1.50E-06 | 1.80E-10 | 68.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YGL259W | YPS5 | SGDID:S000003228 | SAP5 CAALFM_C603030WA CaO19.13032 CaO19.5585 |
Candidapepsin-5 (EC 3.4.23.24) (ACP 5) (Aspartate protease 5) (Secreted aspartic protease 5) |
3.4.23.24 | Candida albicans | 2qzx_a | P43094 | 96.90 | 1.10E-06 | 1.30E-10 | 66.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YGL259W | YPS5 | SGDID:S000003228 | BACE2 AEPLC ALP56 ASP21 CDA13 UNQ418/PRO852 |
Beta-secretase 2 (EC 3.4.23.45) (Aspartic-like protease 56 kDa) (Aspartyl protease 1) (ASP1) (Asp 1) (Beta-site amyloid precursor protein cleaving enzyme 2) (Beta-site APP cleaving enzyme 2) (Down region aspartic protease) (DRAP) (Memapsin-1) (Membrane-associated aspartic protease 1) (Theta-secretase) |
3.4.23.45 | Homo sapiens | Acute Maxillary Sinusitis,Alzheimer Disease,Myositis,Disease Of Mental Health,Anemia, Congenital Dyserythropoietic, Type Ib,Cerebral Amyloid Angiopathy, App-Related,Down Syndrome,Chromosomal Duplication Syndrome |
2ewy_a | Q9Y5Z0 | ENSG00000182240 | BACE2 | 96.50 | 6.50E-06 | 7.70E-10 | 64.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YGL259W | YPS5 | SGDID:S000003228 | CARP |
Rhizopuspepsin (EC 3.4.23.21) |
3.4.23.21 | Rhizopus chinensis | 1uh8_a | P06026 | 97.00 | 9.20E-07 | 1.10E-10 | 66.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YGL259W | YPS5 | SGDID:S000003228 | PGC |
Gastricsin (EC 3.4.23.3) (Pepsinogen C) |
3.4.23.3 | Homo sapiens | Atrophic Gastritis,Hypogonadotropic Hypogonadism 14 With Or Without Anosmia,Gastroesophageal Reflux,Disease Of Mental Health,Gastritis |
1htr_b | P20142 | ENSG00000096088 | PGC | 96.80 | 1.80E-06 | 2.20E-10 | 64.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YGL259W | YPS5 | SGDID:S000003228 | cardA |
Procardosin-A (EC 3.4.23.-) [Cleaved into: Cardosin-A intermediate form 35 kDa subunit; Cardosin-A heavy chain (Cardosin-A 31 kDa subunit); Cardosin-A intermediate form 30 kDa subunit; Cardosin-A light chain (Cardosin-A 15 kDa subunit)] |
3.4.23.- | Cynara cardunculus | 1b5f_a | Q9XFX3 | 96.60 | 4.40E-06 | 5.30E-10 | 60.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YGL259W | YPS5 | SGDID:S000003228 | PEPA1 |
Penicillopepsin-1 (EC 3.4.23.20) (Aspartic protease) (Peptidase A) |
3.4.23.20 | Penicillium janthinellum | 2wea_a | P00798 | 96.60 | 5.30E-06 | 6.40E-10 | 62.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YGL259W | YPS5 | SGDID:S000003228 | EAPA EPN-1 |
Endothiapepsin (EC 3.4.23.22) (Aspartate protease) |
3.4.23.22 | Cryphonectria parasitica | 5p6e_a | P11838 | 97.10 | 6.00E-07 | 7.20E-11 | 68.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |