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YGR185C TYS1 / SGDID:S000003417

SGD CSV

Yeast Systematic Name	Yeast Symbol	SGDID	Analog Name	Analog Description	EC	Organism	Disease	Structure	Uniprot	Human ID	Human Symbol	HHsearch Probability	HHsearch E_value	HHsearch P_value	HHsearch Score	Flag Disease related	Flag Homo sapiens	Flag Escherichia coli
YGR185C	TYS1	SGDID:S000003417	trpS	Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)	6.1.1.2	Geobacillus stearothermophilus		1d2r_c	P00953			100.00	7.60E-47	5.20E-51	348.10	0	0	0
YGR185C	TYS1	SGDID:S000003417	trpS NGO_1045	trpS NGO_1045	6.1.1.2	Neisseria gonorrhoeae		5tev_a	Q5F7X0			100.00	1.20E-48	8.50E-53	362.60	0	0	0
YGR185C	TYS1	SGDID:S000003417	EHI_110680	EHI_110680		Entamoeba histolytica		3hzr_c	C4LUB5			100.00	3.30E-45	2.30E-49	342.10	0	0	0
YGR185C	TYS1	SGDID:S000003417	YARS1 YARS	Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) [Cleaved into: Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed]	6.1.1.1	Homo sapiens	Non-Alcoholic Fatty Liver Disease,Robinow Syndrome, Autosomal Recessive 1,Charcot-Marie-Tooth Disease, Dominant Intermediate C,Neuromuscular Disease,Fatty Liver Disease,Infantile Liver Failure Syndrome,Charcot-Marie-Tooth Disease, Axonal, Type 2d,Autosomal Dominant Distal Hereditary Motor Neuronopathy,Retinal Degeneration,Intellectual Disability - Hypoplastic Corpus Callosum - Preauricular Tag,Hyperinsulinemic Hypoglycemia,Charcot-Marie-Tooth Disease,Fatty Liver Disease, Nonalcoholic 1,Charcot-Marie-Tooth Disease, Axonal, Type 2n,Tooth Disease,Rigid Spine Muscular Dystrophy 1,Charcot-Marie-Tooth Disease, Demyelinating, Type 1b,Charcot-Marie-Tooth Disease And Deafness,Visceral Steatosis, Congenital,Charcot-Marie-Tooth Disease, Recessive Intermediate B,Neuropathy, Congenital Hypomyelinating, 1, Autosomal Recessive,Combined Oxidative Phosphorylation Deficiency 8,Charcot-Marie-Tooth Disease Intermediate Type,Charcot-Marie-Tooth Disease, Axonal, Type 2u,Charcot-Marie-Tooth Disease, Dominant Intermediate B,Charcot-Marie-Tooth Disease, Dominant Intermediate A,Developmental And Epileptic Encephalopathy 29,Perrault Syndrome,Usher Syndrome, Type Iiib,Charcot-Marie-Tooth Disease, Axonal, Type 2e,Charcot-Marie-Tooth Disease, Dominant Intermediate D,Neuronopathy, Distal Hereditary Motor, Type Va	1n3l_a	P54577	ENSG00000134684	YARS1	100.00	1.10E-53	7.70E-58	399.70	1	1	0
YGR185C	TYS1	SGDID:S000003417	trpS2 trpSII DR_1093	Tryptophan--tRNA ligase 2 (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase 2) (TrpRS 2) (Tryptophanyl-tRNA synthetase II) (TrpRS II)	6.1.1.2	Deinococcus radiodurans		1yi8_a	Q9RVD6			100.00	7.90E-51	5.40E-55	378.10	0	0	0
YGR185C	TYS1	SGDID:S000003417	ECU11_0530	Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)	6.1.1.2	Encephalitozoon cuniculi		3tze_a	O96771			100.00	6.60E-43	4.50E-47	328.60	0	0	0
YGR185C	TYS1	SGDID:S000003417	ANIA_01709	ANIA_01709	6.1.1.1	Emericella nidulans		5ihx_a	Q5BCM1			100.00	2.90E-40	2.00E-44	309.10	0	0	0
YGR185C	TYS1	SGDID:S000003417	tyrS NGK_0091	Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)	6.1.1.1	Neisseria gonorrhoeae		6otj_b	B4RP13			100.00	2.00E-39	1.40E-43	308.60	0	0	0
YGR185C	TYS1	SGDID:S000003417	TYS1 MGM104 YGR185C G7522	Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)	6.1.1.1	Saccharomyces cerevisiae		2dlc_x	P36421			100.00	8.90E-75	6.10E-79	547.00	0	0	0
YGR185C	TYS1	SGDID:S000003417	trpS VC_2623	Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)	6.1.1.2	Vibrio cholerae		3sz3_a	Q9KNV7			100.00	2.90E-48	2.00E-52	359.80	0	0	0
YGR185C	TYS1	SGDID:S000003417	trpS PH1921	Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)	6.1.1.2	Pyrococcus horikoshii		3jxe_a	O59584			100.00	2.50E-50	1.70E-54	379.20	0	0	0
YGR185C	TYS1	SGDID:S000003417	tyrS MJ0389	Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)	6.1.1.1	Methanocaldococcus jannaschii		4nx2_a	Q57834			100.00	9.10E-47	6.30E-51	344.50	0	0	0
YGR185C	TYS1	SGDID:S000003417	tyrS APE_2074.1	Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)	6.1.1.1	Aeropyrum pernix		2cya_a	Q9YA64			100.00	3.50E-52	2.40E-56	389.10	0	0	0
YGR185C	TYS1	SGDID:S000003417	GL50803_003032 GL50803_3032	GL50803_003032 GL50803_3032	6.1.1.2	Giardia intestinalis		3foc_a	A8B8N3			100.00	1.70E-43	1.20E-47	334.20	0	0	0
YGR185C	TYS1	SGDID:S000003417	trpS BSU11420	Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)	6.1.1.2	Bacillus subtilis		3prh_a	P21656			100.00	6.90E-50	4.70E-54	374.90	0	0	0
YGR185C	TYS1	SGDID:S000003417	PF3D7_0807900	PF3D7_0807900	6.1.1.1	Plasmodium falciparum		3vgj_b	Q8IAR7			100.00	7.90E-53	5.40E-57	393.80	0	0	0
YGR185C	TYS1	SGDID:S000003417	tyrS AF_0776	Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)	6.1.1.1	Archaeoglobus fulgidus		2cyb_a	O29482			100.00	8.80E-50	6.10E-54	367.60	0	0	0
YGR185C	TYS1	SGDID:S000003417	tyrS TT_C1033	Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)	6.1.1.1	Thermus thermophilus		1h3e_a	P83453			100.00	3.20E-40	2.20E-44	314.20	0	0	0
YGR185C	TYS1	SGDID:S000003417	YARS2 CGI-04	Tyrosine--tRNA ligase, mitochondrial (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)	6.1.1.1	Homo sapiens	Sideroblastic Anemia,Myopathy, Lactic Acidosis, And Sideroblastic Anemia,Myopathy,Charcot-Marie-Tooth Disease, Dominant Intermediate C,Mitochondrial Myopathy,Combined Oxidative Phosphorylation Deficiency 12,Charcot-Marie-Tooth Disease, Axonal, Type 2d,Autosomal Dominant Distal Hereditary Motor Neuronopathy,Optic Atrophy 1,Mitochondrial Disorders,Charcot-Marie-Tooth Disease,Charcot-Marie-Tooth Disease, Axonal, Type 2n,Rigid Spine Muscular Dystrophy 1,Myopathy, Lactic Acidosis, And Sideroblastic Anemia 2,Charcot-Marie-Tooth Disease, Recessive Intermediate B,Lactic Acidosis,Optic Atrophy 5,Combined Oxidative Phosphorylation Deficiency 20,Neuropathy, Congenital Hypomyelinating, 1, Autosomal Recessive,Charcot-Marie-Tooth Disease Intermediate Type,Sideroblastic Anemia With B-Cell Immunodeficiency, Periodic Fevers, And Developmental Delay,Encephalopathy Due To Defective Mitochondrial And Peroxisomal Fission 1,Perrault Syndrome,Mitochondrial Dna Depletion Syndrome 4a,Myopathy, Lactic Acidosis, And Sideroblastic Anemia 3,Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes,Pearson Marrow-Pancreas Syndrome,Myopathy, Lactic Acidosis, And Sideroblastic Anemia 1,Neuronopathy, Distal Hereditary Motor, Type Va	2pid_b	Q9Y2Z4	ENSG00000139131	YARS2	100.00	3.00E-43	2.00E-47	325.90	1	1	0
YGR185C	TYS1	SGDID:S000003417	tyrS BD94_1246	tyrS BD94_1246		Elizabethkingia anophelis		6n0w_a	A0A077EBU6			100.00	3.30E-41	2.20E-45	322.80	0	0	0
YGR185C	TYS1	SGDID:S000003417	tyrS b1637 JW1629	Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)	6.1.1.1	Escherichia coli		1vbm_b	P0AGJ9			100.00	1.00E-41	7.20E-46	312.40	0	0	1
YGR185C	TYS1	SGDID:S000003417	trpS TTHA1227	trpS TTHA1227	6.1.1.2	Thermus thermophilus		2el7_a	Q5SIY7			100.00	8.00E-49	5.50E-53	362.80	0	0	0
YGR185C	TYS1	SGDID:S000003417	CPC735_063460	CPC735_063460	6.1.1.1	Coccidioides posadasii		5ijx_a	C5P455			100.00	1.70E-41	1.10E-45	316.70	0	0	0
YGR185C	TYS1	SGDID:S000003417	trpS Z4737 ECs4226	Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)	6.1.1.2	Escherichia coli		5v0i_a	P67589			100.00	3.20E-47	2.20E-51	352.20	0	0	1
YGR185C	TYS1	SGDID:S000003417	WARS2	Tryptophan--tRNA ligase, mitochondrial (EC 6.1.1.2) ((Mt)TrpRS) (Tryptophanyl-tRNA synthetase) (TrpRS)	6.1.1.2	Homo sapiens	Robinow Syndrome, Autosomal Recessive 1,Bulbar Polio,Trichohepatoenteric Syndrome 1,Neurodevelopmental Disorder, Mitochondrial, With Abnormal Movements And Lactic Acidosis, With Or Without Seizures,Spastic Quadriplegia,Lactic Acidosis,Perrault Syndrome,Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes	5ekd_b	Q9UGM6	ENSG00000116874	WARS2	100.00	2.30E-48	1.60E-52	360.60	1	1	0
YGR185C	TYS1	SGDID:S000003417	tyrS	Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)	6.1.1.1	Geobacillus stearothermophilus		2ts1_a	P00952			100.00	8.30E-42	5.70E-46	324.10	0	0	0
YGR185C	TYS1	SGDID:S000003417	cgd7_1490	cgd7_1490	6.1.1.2	Cryptosporidium parvum		3hv0_b	Q5CYP8			100.00	1.50E-43	1.00E-47	332.20	0	0	0
YGR185C	TYS1	SGDID:S000003417	tyrS HPG27_731	tyrS HPG27_731	6.1.1.1	Helicobacter pylori		6byq_a	B5Z7D7			100.00	1.00E-40	7.00E-45	315.30	0	0	0
YGR185C	TYS1	SGDID:S000003417	trpS HI_0637	Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)	6.1.1.2	Haemophilus influenzae		6dfu_a	P43835			100.00	3.90E-48	2.70E-52	358.40	0	0	0
YGR185C	TYS1	SGDID:S000003417	trpS Cj0388	Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)	6.1.1.2	Campylobacter jejuni		3tzl_a	Q9PIB4			100.00	2.40E-48	1.70E-52	358.00	0	0	0
YGR185C	TYS1	SGDID:S000003417	trpS CT_585	Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)	6.1.1.2	Chlamydia trachomatis		6ncr_a	O84589			100.00	4.30E-51	2.90E-55	379.60	0	0	0
YGR185C	TYS1	SGDID:S000003417	Tb927.3.5580	Tb927.3.5580	6.1.1.2	Trypanosoma brucei		3i05_b	Q580R7			100.00	3.20E-43	2.20E-47	329.30	0	0	0
YGR185C	TYS1	SGDID:S000003417	tyrS ABSDF0019	tyrS ABSDF0019	6.1.1.1	Acinetobacter baumannii		6bqy_b	B0VML7			100.00	4.80E-41	3.30E-45	317.70	0	0	0
YGR185C	TYS1	SGDID:S000003417	WARS1 IFI53 WARS WRS	Tryptophan--tRNA ligase, cytoplasmic (EC 6.1.1.2) (Interferon-induced protein 53) (IFP53) (Tryptophanyl-tRNA synthetase) (TrpRS) (hWRS) [Cleaved into: T1-TrpRS; T2-TrpRS]	6.1.1.2	Homo sapiens	Robinow Syndrome, Autosomal Recessive 1,Noonan Syndrome 1,Charcot-Marie-Tooth Disease,Neuronopathy, Distal Hereditary Motor, Type Ix,Charcot-Marie-Tooth Disease, Axonal, Type 2u,Developmental And Epileptic Encephalopathy 29	1o5t_a	P23381	ENSG00000140105	WARS1	100.00	2.10E-43	1.40E-47	330.50	1	1	0
YGR185C	TYS1	SGDID:S000003417	PF3D7_1336900	PF3D7_1336900	6.1.1.2	Plasmodium falciparum		4j75_a	Q8IDW3			100.00	2.40E-45	1.70E-49	344.90	0	0	0
YGR185C	TYS1	SGDID:S000003417	tyrS PH1011	Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)	6.1.1.1	Pyrococcus horikoshii		2cyc_a	O58739			100.00	8.20E-50	5.70E-54	374.70	0	0	0
YGR185C	TYS1	SGDID:S000003417	WRS1 YOL097C HRE432	Tryptophan--tRNA ligase, cytoplasmic (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)	6.1.1.2	Saccharomyces cerevisiae		2ip1_a	Q12109			100.00	6.60E-44	4.50E-48	337.50	0	0	0
YGR185C	TYS1	SGDID:S000003417	trpS APE_2461.1	Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)	6.1.1.2	Aeropyrum pernix		3a04_a	Q9Y924			100.00	1.10E-46	7.30E-51	352.00	0	0	0
YGR185C	TYS1	SGDID:S000003417	BD94_0195	BD94_0195		Elizabethkingia anophelis		6mtk_a	A0A077EER2			100.00	6.00E-49	4.10E-53	362.30	0	0	0
YGR185C	TYS1	SGDID:S000003417	cyt-18 B18P24.070 NCU03030	Tyrosine--tRNA ligase, mitochondrial (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)	6.1.1.1	Neurospora crassa		1y42_x	P12063			100.00	2.20E-42	1.50E-46	322.90	0	0	0
YGR185C	TYS1	SGDID:S000003417	YARS MIMI_L124	Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)	6.1.1.1	Acanthamoeba polyphaga		2j5b_a	Q5UPJ7			100.00	1.20E-49	8.50E-54	369.60	0	0	0
YGR185C	TYS1	SGDID:S000003417	LDBPK_141460	LDBPK_141460		Leishmania donovani		5usf_a	E9BC28			100.00	2.60E-44	1.80E-48	360.20	0	0	0
YGR185C	TYS1	SGDID:S000003417	trpS MPN_265 MP568	Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)	6.1.1.2	Mycoplasma pneumoniae		2yy5_b	P75510			100.00	7.30E-49	5.00E-53	364.50	0	0	0
YGR185C	TYS1	SGDID:S000003417	trpS TM_0492	Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)	6.1.1.2	Thermotoga maritima		2g36_a	Q9WYW2			100.00	1.20E-47	8.60E-52	355.70	0	0	0