| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YGR258C | RAD2 | SGDID:S000003490 | GEN1 |
Flap endonuclease GEN homolog 1 (EC 3.1.-.-) |
3.1.-.- | Homo sapiens | Xeroderma Pigmentosum, Variant Type,Fanconi Anemia, Complementation Group A,Xeroderma Pigmentosum, Complementation Group G,Optic Atrophy 9,Optic Atrophy 6 |
5t9j_b | Q17RS7 | ENSG00000178295 | GEN1 | 99.80 | 4.20E-24 | 4.10E-28 | 242.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YGR258C | RAD2 | SGDID:S000003490 | RAD2 YGR258C |
DNA repair protein RAD2 (EC 3.1.-.-) |
3.1.-.- | Saccharomyces cerevisiae | 2lox_b | P07276 | 99.60 | 3.10E-20 | 2.00E-24 | 145.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGR258C | RAD2 | SGDID:S000003490 | EXO1 EXOI HEX1 |
Exonuclease 1 (hExo1) (EC 3.1.-.-) (Exonuclease I) (hExoI) |
3.1.-.- | Homo sapiens | Rothmund-Thomson Syndrome, Type 2,Baller-Gerold Syndrome,Colorectal Cancer,Werner Syndrome,Xeroderma Pigmentosum, Variant Type,Fanconi Anemia, Complementation Group A,Xeroderma Pigmentosum, Complementation Group G,Chilblain Lupus 1,Lynch Syndrome,Ophthalmomyiasis,Seckel Syndrome,Aicardi-Goutieres Syndrome,Pigmentary Disorder, Reticulate, With Systemic Manifestations, X-Linked,Vasculopathy, Retinal, With Cerebral Leukoencephalopathy And Systemic Manifestations,Lung Cancer |
3qe9_y | Q9UQ84 | ENSG00000174371 | EXO1 | 99.40 | 5.50E-17 | 5.80E-21 | 173.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YGR258C | RAD2 | SGDID:S000003490 | fen AF_0264 |
Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (Flap structure-specific endonuclease 1) |
3.1.-.- | Archaeoglobus fulgidus | 1rxv_b | O29975 | 99.80 | 2.40E-24 | 2.50E-28 | 228.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGR258C | RAD2 | SGDID:S000003490 | xni ygdG Z4115 ECs3658 |
Flap endonuclease Xni (FEN) (EC 3.1.-.-) |
3.1.-.- | Escherichia coli | 3zd9_a | Q8X6R9 | 99.20 | 7.10E-16 | 7.50E-20 | 156.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
| YGR258C | RAD2 | SGDID:S000003490 | fen |
fen |
3.1.-.- | Desulfurococcus amylolyticus | 3ory_a | F2Z289 | 99.90 | 7.70E-27 | 8.00E-31 | 252.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGR258C | RAD2 | SGDID:S000003490 | fen MJ1444 |
Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (Flap structure-specific endonuclease 1) |
3.1.-.- | Methanocaldococcus jannaschii | 1a76_a | Q58839 | 99.80 | 1.80E-25 | 1.90E-29 | 237.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGR258C | RAD2 | SGDID:S000003490 | FEN1 RAD2 |
Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (DNase IV) (Flap structure-specific endonuclease 1) (Maturation factor 1) (MF1) (hFEN-1) |
3.1.-.- | Homo sapiens | Rothmund-Thomson Syndrome, Type 2,Spinocerebellar Ataxia Type 1 With Axonal Neuropathy,Baller-Gerold Syndrome,Noonan Syndrome 1,Cockayne Syndrome,Werner Syndrome,Xeroderma Pigmentosum, Complementation Group A,Xeroderma Pigmentosum, Variant Type,Fanconi Anemia, Complementation Group A,Xeroderma Pigmentosum, Complementation Group F,Xeroderma Pigmentosum, Complementation Group G,Aicardi-Goutieres Syndrome,Vitelliform Macular Dystrophy,Huntington Disease,Fetal Akinesia Deformation Sequence 1,Ataxia, Early-Onset, With Oculomotor Apraxia And Hypoalbuminemia,Bloom Syndrome |
5um9_a | P39748 | ENSG00000168496 | FEN1 | 99.80 | 6.10E-25 | 6.50E-29 | 234.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YGR258C | RAD2 | SGDID:S000003490 | fen fen-1 PF1414 |
Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (Flap structure-specific endonuclease 1) |
3.1.-.- | Pyrococcus furiosus | 1b43_a | O93634 | 99.80 | 9.80E-26 | 1.00E-29 | 241.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGR258C | RAD2 | SGDID:S000003490 | fen SSO0179 |
Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (Flap structure-specific endonuclease 1) |
3.1.-.- | Saccharolobus solfataricus | 2izo_a | Q980U8 | 99.80 | 2.30E-26 | 2.50E-30 | 246.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YGR258C | RAD2 | SGDID:S000003490 | CTHT_0007290 |
CTHT_0007290 |
Chaetomium thermophilum | 5co8_c | G0RYN2 | 99.70 | 2.90E-22 | 2.80E-26 | 226.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YGR258C | RAD2 | SGDID:S000003490 | fen MK0566 |
Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (Flap structure-specific endonuclease 1) |
3.1.-.- | Methanopyrus kandleri | 4wa8_a | Q8TXU4 | 99.80 | 7.20E-26 | 7.60E-30 | 243.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |