| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YHR099W | TRA1 | SGDID:S000001141 | ATR FRP1 |
Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1) |
2.7.11.1 | Homo sapiens | Lattice Corneal Dystrophy,Chronic Active Epstein-Barr Virus Infection,Lung Large Cell Carcinoma,Cerebellar Disease,Fanconi Anemia, Complementation Group I,Blepharophimosis,Ovarian Cancer,Breast Cancer,Microcephaly,Xeroderma Pigmentosum, Variant Type,Fanconi Anemia, Complementation Group A,Seckel Syndrome,Cutaneous Telangiectasia And Cancer Syndrome, Familial,Autosomal Recessive Cerebellar Ataxia,Nijmegen Breakage Syndrome,Leukemia, Chronic Lymphocytic,Ceroid Lipofuscinosis, Neuronal, 2,Epithelial-Stromal Tgfbi Dystrophy,Ataxia-Telangiectasia,Seckel Syndrome 1,Isolated Growth Hormone Deficiency, Type Ia |
5yz0_b | Q13535 | ENSG00000175054 | ATR | 100.00 | 4.00E-94 | 2.90E-98 | 1164.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YHR099W | TRA1 | SGDID:S000001141 | PRKDC HYRC HYRC1 |
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460) |
2.7.11.1 | Homo sapiens | Severe Combined Immunodeficiency,Melanoma,Immunodeficiency 26,Combined Immunodeficiency,Hemangioma Of Subcutaneous Tissue,Cerebellar Disease,Thymus Lymphoma,Dubowitz Syndrome,Severe Combined Immunodeficiency With Sensitivity To Ionizing Radiation,Microcephaly,Werner Syndrome,Xeroderma Pigmentosum, Variant Type,Fanconi Anemia, Complementation Group A,Omenn Syndrome,Hutchinson-Gilford Progeria Syndrome,Alpha-Thalassemia,Immunodeficiency 26 With Or Without Neurologic Abnormalities,Seckel Syndrome,Alpha-Thalassemia/Mental Retardation Syndrome, X-Linked,Lig4 Syndrome,Autosomal Recessive Cerebellar Ataxia,Ataxia-Telangiectasia |
5luq_b | P78527 | ENSG00000253729 | PRKDC | 100.00 | 6.00E-190 | 4.00E-194 | 2240.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YHR099W | TRA1 | SGDID:S000001141 | MEC1 ESR1 SAD3 YBR136W YBR1012 |
Serine/threonine-protein kinase MEC1 (EC 2.7.11.1) (ATR homolog) (DNA-damage checkpoint kinase MEC1) (Mitosis entry checkpoint protein 1) |
2.7.11.1 | Saccharomyces cerevisiae | 5x6o_c | P38111 | 100.00 | 4.40E-98 | 3.00E-102 | 1166.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YHR099W | TRA1 | SGDID:S000001141 | TOR2 DRR2 TSC14 YKL203C |
Serine/threonine-protein kinase TOR2 (EC 2.7.1.67) (EC 2.7.11.1) (Dominant rapamycin resistance protein 2) (Phosphatidylinositol 4-kinase TOR2) (PI4-kinase TOR2) (PI4K TOR2) (PtdIns-4-kinase TOR2) (Target of rapamycin kinase 2) (Temperature-sensitive CSG2 suppressor protein 14) |
2.7.1.67,2.7.11.1, | Saccharomyces cerevisiae | 6emk_c | P32600 | 100.00 | 2.80E-90 | 2.10E-94 | 1161.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YHR099W | TRA1 | SGDID:S000001141 | PIK3C3 VPS34 |
Phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3-kinase type 3) (PI3K type 3) (PtdIns-3-kinase type 3) (EC 2.7.1.137) (Phosphatidylinositol 3-kinase p100 subunit) (Phosphoinositide-3-kinase class 3) (hVps34) |
2.7.1.137 | Homo sapiens | Myopathy,Alzheimer Disease,Amyotrophic Lateral Sclerosis 1,Parkinson Disease, Late-Onset,Centronuclear Myopathy,Danon Disease,Huntington Disease,Kaposi Sarcoma,Myopathy, Centronuclear, X-Linked,Myopathy, X-Linked, With Excessive Autophagy |
4uwh_a | Q8NEB9 | ENSG00000078142 | PIK3C3 | 100.00 | 2.20E-34 | 1.60E-38 | 395.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YHR099W | TRA1 | SGDID:S000001141 | ATM |
Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated) |
2.7.11.1 | Homo sapiens | Skin Melanoma,Richter'S Syndrome,Retinitis Pigmentosa,Cll/Sll,Adenoid Cystic Carcinoma,Seizure Disorder,Cowden Syndrome,Plasma Cell Neoplasm,Rothmund-Thomson Syndrome, Type 2,Cervical Adenoma Malignum,Breast Juvenile Papillomatosis,Bilateral Breast Cancer,Synchronous Bilateral Breast Carcinoma,B-Cell Non-Hodgkin Lymphoma,Diffuse Gastric Cancer,B-Cell Lymphoma,Retinal Cancer,Spinocerebellar Ataxia Type 1 With Axonal Neuropathy,Endocrine Exophthalmos,Leukemia,Maxillary Sinus Adenocarcinoma,Inherited Cancer-Predisposing Syndrome,Glioma,Leukemia, Acute Myeloid,Sporadic Breast Cancer,Telangiectasis,Hematologic Cancer,Combined Immunodeficiency,Oculomotor Apraxia,Dysplastic Nevus Syndrome,Dyskeratosis Congenita,Urethra Clear Cell Adenocarcinoma,Cerebellar Disease,Bile Duct Cystadenoma,Dystonia,T-Cell Prolymphocytic Leukemia,Prolymphocytic Leukemia,Ovarian Cancer,Burkitt Lymphoma,Testicular Cancer,T-Cell Acute Lymphoblastic Leukemia,Breast Cancer,Glioblastoma,Hereditary Breast Ovarian Cancer Syndrome,High Grade Glioma,Gliosarcoma,Giant Cell Glioblastoma,Mediastinum Liposarcoma,Colorectal Cancer,Acute Anterolateral Myocardial Infarction,Severe Combined Immunodeficiency With Sensitivity To Ionizing Radiation,Proctitis,Premature Menopause,Microcephaly,Rhabdomyosarcoma,Werner Syndrome,Xeroderma Pigmentosum, Complementation Group A,Xeroderma Pigmentosum, Variant Type,Fanconi Anemia, Complementation Group A,Skin Carcinoma,Hutchinson-Gilford Progeria Syndrome,Prostate Cancer,Disease Of Mental Health,Aceruloplasminemia,Lynch Syndrome,Chromosome 13q14 Deletion Syndrome,Lymphoma, Non-Hodgkin, Familial,Renal Cell Carcinoma, Papillary, 1,Esophageal Cancer,Seckel Syndrome,Asphyxiating Thoracic Dystrophy,Immune Deficiency Disease,Myelodysplastic Syndrome,Female Breast Cancer,Gastric Cancer, Hereditary Diffuse,Tumor Predisposition Syndrome,Autosomal Recessive Disease,Autosomal Genetic Disease,Mantle Cell Lymphoma,Lig4 Syndrome,Pigmentary Disorder, Reticulate, With Systemic Manifestations, X-Linked,Nephrolithiasis/Osteoporosis, Hypophosphatemic, 2,Cervical Dystonia,Colorectal Adenocarcinoma,Cutaneous Telangiectasia And Cancer Syndrome, Familial,Renal Cell Carcinoma, Nonpapillary,Autosomal Recessive Cerebellar Ataxia,Hereditary Ataxia,Lymphoma,Cataract 38,Apraxia,Nijmegen Breakage Syndrome,Leukemia, Chronic Lymphocytic,Li-Fraumeni Syndrome,Ataxia-Telangiectasia,Myeloma, Multiple,Medulloblastoma,Ataxia, Early-Onset, With Oculomotor Apraxia And Hypoalbuminemia,Melanoma, Cutaneous Malignant 1,Bloom Syndrome,Primary Autosomal Recessive Microcephaly,Lung Cancer,Ocular Motor Apraxia,Pancreatic Cancer |
5np0_b | Q13315 | ENSG00000149311 | ATM | 100.00 | 2.70E-93 | 1.90E-97 | 1161.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YHR099W | TRA1 | SGDID:S000001141 | TRA1 YHR099W |
Transcription-associated protein 1 (p400 kDa component of SAGA) |
Saccharomyces cerevisiae | 5ojs_t | P38811 | 100.00 | 0 | 0 | 5416.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YHR099W | TRA1 | SGDID:S000001141 | TEL1 YBL088C YBL0706 |
Serine/threonine-protein kinase TEL1 (EC 2.7.11.1) (ATM homolog) (DNA-damage checkpoint kinase TEL1) (Telomere length regulation protein 1) |
2.7.11.1 | Saccharomyces cerevisiae | 6jxc_a | P38110 | 100.00 | 1.80E-87 | 1.30E-91 | 1081.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YHR099W | TRA1 | SGDID:S000001141 | Pi3K59F Dmel\CG5373 DmVps34 dPI3K dVps34 PI(3)K PI3K PI3K-59F PI3K59F Pi3k59F PI3K_59F Pi3K_59F PI[[3]]K PIK359F VPS34 Vps34 vps34 CG5373 Dmel_CG5373 |
Pi3K59F Dmel\CG5373 DmVps34 dPI3K dVps34 PI(3)K PI3K PI3K-59F PI3K59F Pi3k59F PI3K_59F Pi3K_59F PI[[3]]K PIK359F VPS34 Vps34 vps34 CG5373 Dmel_CG5373 |
2.7.1.137 | Drosophila melanogaster | 2x6h_b | Q9W1M7 | 100.00 | 5.40E-34 | 3.80E-38 | 395.30 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | |||
| YHR099W | TRA1 | SGDID:S000001141 | PAS_chr1-4_0571 |
PAS_chr1-4_0571 |
Komagataella phaffii | 5oej_b | C4QYV4 | 100.00 | 0 | 0 | 5243.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |