Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
YKL197C | PEX1 | SGDID:S000001680 | VPS4B SKD1 VPS42 MIG1 |
Vacuolar protein sorting-associated protein 4B (EC 3.6.4.6) (Cell migration-inducing gene 1 protein) (Suppressor of K(+) transport growth defect 1) (Protein SKD1) |
3.6.4.6 | Homo sapiens | Parotid Gland Cancer,Submandibular Gland Cancer,Dentin Dysplasia,Submandibular Gland Disease,Dentin Dysplasia, Type I |
1xwi_a | O75351 | ENSG00000119541 | VPS4B | 98.30 | 2.30E-10 | 2.40E-14 | 119.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YKL197C | PEX1 | SGDID:S000001680 | SPAST ADPSP FSP2 KIAA1083 SPG4 |
Spastin (EC 5.6.1.1) (Spastic paraplegia 4 protein) |
5.6.1.1 | Homo sapiens | Paraplegia,Chromosome 1q21.1 Duplication Syndrome,Dystonia 9,Spastic Paraplegia 42, Autosomal Dominant,Zellweger Syndrome,Seizure Disorder,Spasticity,Amyotrophic Lateral Sclerosis 1,Motor Neuron Disease,Hereditary Spastic Paraplegia 30,Hereditary Spastic Paraplegia 72,Spastic Paraplegia 17, Autosomal Dominant,Spastic Paraplegia 15, Autosomal Recessive,Spastic Paraplegia 5a, Autosomal Recessive,Spastic Paraplegia 56, Autosomal Recessive,Hereditary Spastic Paraplegia,Spastic Paraplegia 43, Autosomal Recessive,Pure Hereditary Spastic Paraplegia,Spastic Paraparesis,Spastic Paraplegia 4,Chromosome 17p13.3, Centromeric, Duplication Syndrome,Spastic Paraplegia 26, Autosomal Recessive,Spastic Paraplegia 20, Autosomal Recessive,Spastic Paraplegia 41, Autosomal Dominant,Spastic Diplegia,Spastic Paraplegia 48, Autosomal Recessive,Spastic Paraplegia 8, Autosomal Dominant,Disease Of Mental Health,Spastic Paraplegia 33, Autosomal Dominant,Spastic Paraplegia 31, Autosomal Dominant,Neuropathy, Hereditary Sensory, Type Id,Spastic Paraplegia 16, X-Linked,Spastic Paraplegia 61, Autosomal Recessive,Spastic Paraplegia 10, Autosomal Dominant,Spastic Paraplegia 11, Autosomal Recessive,Spastic Paraplegia 12, Autosomal Dominant,Spastic Paraplegia 14, Autosomal Recessive,Spastic Paraplegia 3, Autosomal Dominant,Spastic Paraplegia 47, Autosomal Recessive,Spastic Paraplegia 4, Autosomal Dominant,Spastic Paraplegia 13, Autosomal Dominant,Myopathy, Proximal, With Ophthalmoplegia,Spastic Paraplegia 39, Autosomal Recessive,Spastic Paraplegia 46, Autosomal Recessive,Masa Syndrome,Charcot-Marie-Tooth Disease, Axonal, Type 2e,Spastic Paraplegia 2, X-Linked,Spastic Paraplegia 6, Autosomal Dominant |
5z6r_a | Q9UBP0 | ENSG00000021574 | SPAST | 97.90 | 3.50E-09 | 3.40E-13 | 116.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YKL197C | PEX1 | SGDID:S000001680 | CTHT_0002840 |
CTHT_0002840 |
Chaetomium thermophilum | 6mat_b | G0RZG1 | 97.90 | 4.30E-09 | 4.40E-13 | 125.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YKL197C | PEX1 | SGDID:S000001680 | PSMD2 TRAP2 |
26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2) |
Homo sapiens | Angelman Syndrome,Cystic Fibrosis |
6msb_f | Q13200 | ENSG00000175166 | PSMD2 | 98.00 | 3.10E-09 | 2.80E-13 | 119.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
YKL197C | PEX1 | SGDID:S000001680 | MSMEG_0858 |
MSMEG_0858 |
Mycolicibacterium smegmatis | 5e7p_a | A0QQS4 | 99.60 | 1.80E-19 | 1.80E-23 | 215.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YKL197C | PEX1 | SGDID:S000001680 | VPS4 CSC1 DID6 END13 GRD13 VPL4 VPT10 YPR173C P9705.10 |
Vacuolar protein sorting-associated protein 4 (DOA4-independent degradation protein 6) (Protein END13) (Vacuolar protein-targeting protein 10) |
Saccharomyces cerevisiae | 3eie_a | P52917 | 98.00 | 1.40E-09 | 1.50E-13 | 113.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YKL197C | PEX1 | SGDID:S000001680 | PRE7 PRS3 PTS1 YBL041W YBL0407 |
Proteasome subunit beta type-6 (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) |
3.4.25.1 | Saccharomyces cerevisiae | 6fvy_m | P23724 | 98.20 | 6.40E-10 | 5.90E-14 | 124.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YKL197C | PEX1 | SGDID:S000001680 | PSMD13 |
26S proteasome non-ATPase regulatory subunit 13 (26S proteasome regulatory subunit RPN9) (26S proteasome regulatory subunit S11) (26S proteasome regulatory subunit p40.5) |
Homo sapiens | Histrionic Personality Disorder |
6msb_a | Q9UNM6 | ENSG00000185627 | PSMD13 | 98.00 | 2.00E-09 | 1.80E-13 | 120.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
YKL197C | PEX1 | SGDID:S000001680 | vat Ta0840 |
VCP-like ATPase |
Thermoplasma acidophilum | 5g4f_c | O05209 | 98.20 | 5.10E-10 | 5.20E-14 | 131.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YKL197C | PEX1 | SGDID:S000001680 | FIGNL1 |
Fidgetin-like protein 1 (EC 3.6.4.-) |
3.6.4.- | Homo sapiens | 3d8b_a | Q6PIW4 | ENSG00000132436 | FIGNL1 | 98.30 | 1.40E-10 | 1.40E-14 | 124.90 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
YKL197C | PEX1 | SGDID:S000001680 | TON_0529 |
TON_0529 |
Thermococcus onnurineus | 3k1j_a | B6YU74 | 98.50 | 3.70E-11 | 3.60E-15 | 139.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YKL197C | PEX1 | SGDID:S000001680 | VCP |
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP) |
3.6.4.6 | Homo sapiens | Muscular Disease,Amyotrophic Lateral Sclerosis 6 With Or Without Frontotemporal Dementia,Zellweger Syndrome,Supranuclear Palsy, Progressive, 1,Retinitis Pigmentosa,Myopathy,Myofibrillar Myopathy,Muscle Tissue Disease,Neuromuscular Disease,Alzheimer Disease,Nominal Aphasia,Amyotrophic Lateral Sclerosis 1,Myositis,Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 1,Early-Onset, Autosomal Dominant Alzheimer Disease,Amyotrophic Lateral Sclerosis 8,Lateral Sclerosis,Motor Neuron Disease,Autosomal Dominant Limb-Girdle Muscular Dystrophy,Muscular Dystrophy,Movement Disease,Progressive Non-Fluent Aphasia,Dyscalculia,Inclusion Body Myopathy With Early-Onset Paget Disease Of Bone With Or Without Frontotemporal Dementia 1,Hereditary Spastic Paraplegia,Cystic Fibrosis,Machado-Joseph Disease,Spastic Paraplegia-Paget Disease Of Bone Syndrome,Adult-Onset Distal Myopathy Due To Vcp Mutation,Multisystem Proteinopathy,Dementia,Paget'S Disease Of Bone,Cockayne Syndrome,Alexia,Inclusion Body Myopathy With Early-Onset Paget Disease With Or Without Frontotemporal Dementia 1,Charcot-Marie-Tooth Disease,Parkinson Disease, Late-Onset,Perry Syndrome,Speech And Communication Disorders,Progressive Muscular Atrophy,Tooth Disease,Pick Disease Of Brain,Werner Syndrome,Autosomal Dominant Cerebellar Ataxia,Neuronal Ceroid Lipofuscinosis,Mammary Paget'S Disease,Breast Adenocarcinoma,Disease Of Mental Health,Dementia, Lewy Body,Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 6,Fanconi Anemia, Complementation Group G,Nonaka Myopathy,Alzheimer Disease 7,Amyotrophic Lateral Sclerosis 16, Juvenile,Ehlers-Danlos Syndrome, Spondylodysplastic Type, 3,Inclusion Body Myopathy With Paget Disease Of Bone And Frontotemporal Dementia,Aphasia,Writing Disorder,Inclusion Body Myositis,Associative Agnosia,Amyotrophic Lateral Sclerosis Type 6,Amyotrophic Lateral Sclerosis Type 14,Agraphia,Charcot-Marie-Tooth Disease, Axonal, Type 2e,Frontotemporal Dementia,Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 7 |
4ko8_a | P55072 | ENSG00000165280 | VCP | 98.20 | 2.90E-10 | 2.90E-14 | 128.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YKL197C | PEX1 | SGDID:S000001680 | PRE3 YJL001W J1407 |
Proteasome subunit beta type-1 (EC 3.4.25.1) (Macropain subunit PRE3) (Multicatalytic endopeptidase complex subunit PRE3) (Proteasome component PRE3) (Proteinase YSCE subunit PRE3) |
3.4.25.1 | Saccharomyces cerevisiae | 6fvw_h | P38624 | 98.40 | 1.00E-10 | 9.40E-15 | 131.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |