







Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
YLL050C | COF1 | SGDID:S000003973 | EHI7A_006660 |
EHI7A_006660 |
Entamoeba histolytica | 4liz_a | N9TKD6 | 99.90 | 5.50E-31 | 3.80E-35 | 168.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YLL050C | COF1 | SGDID:S000003973 | Twf1 Ptk9 |
Twinfilin-1 (Protein A6) |
Mus musculus | 1m4j_b | Q91YR1 | 99.90 | 1.70E-30 | 1.20E-34 | 165.60 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | ||||
YLL050C | COF1 | SGDID:S000003973 | COF1 YLL050C L0596 |
Cofilin (Actin-depolymerizing factor 1) |
Saccharomyces cerevisiae | 1cof_a | Q03048 | 100.00 | 3.10E-34 | 2.10E-38 | 183.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YLL050C | COF1 | SGDID:S000003973 | BN1205_087130 TGVEG_220400 |
BN1205_087130 TGVEG_220400 |
Toxoplasma gondii | 2mot_a | B9Q2C8 | 99.90 | 1.30E-28 | 8.70E-33 | 152.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YLL050C | COF1 | SGDID:S000003973 | TWF2 PTK9L MSTP011 |
Twinfilin-2 (A6-related protein) (hA6RP) (Protein tyrosine kinase 9-like) (Twinfilin-1-like protein) |
Homo sapiens | 2vac_a | Q6IBS0 | ENSG00000247596 | TWF2 | 99.90 | 1.80E-29 | 1.30E-33 | 159.40 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | ||
YLL050C | COF1 | SGDID:S000003973 | cof1 adf1 SPAC20G4.06c |
Cofilin (Actin-depolymerizing factor 1) |
Schizosaccharomyces pombe | 2i2q_a | P78929 | 99.90 | 4.90E-32 | 3.40E-36 | 171.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YLL050C | COF1 | SGDID:S000003973 | ADF2 PBK173_000303300 PBNK65E_000295500 PBNK65NY_000295000 PBSP11A_000294900 PBSP11RLL_000295400 |
ADF2 PBK173_000303300 PBNK65E_000295500 PBNK65NY_000295000 PBSP11A_000294900 PBSP11RLL_000295400 |
Plasmodium berghei | 2xfa_a | Q3YPH0 | 99.90 | 2.60E-29 | 1.80E-33 | 161.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YLL050C | COF1 | SGDID:S000003973 | CFL1 CFL |
Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform) |
Homo sapiens | Congenital Structural Myopathy,Corticobasal Degeneration,Smith-Lemli-Opitz Syndrome,Spinal Muscular Atrophy,Dilated Cardiomyopathy,Myasthenic Syndrome, Congenital, 4c, Associated With Acetylcholine Receptor Deficiency,Juvenile Nasopharyngeal Angiofibroma,Disease Of Mental Health,Congenital Myasthenic Syndrome,Camptodactyly-Arthropathy-Coxa Vara-Pericarditis Syndrome,Polycystic Kidney Disease 3 With Or Without Polycystic Liver Disease |
3j0s_p | P23528 | ENSG00000172757 | CFL1 | 99.90 | 6.80E-30 | 4.60E-34 | 167.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
YLL050C | COF1 | SGDID:S000003973 | DBN1 D0S117E |
Drebrin (Developmentally-regulated brain protein) |
Homo sapiens | Alzheimer Disease,Myasthenic Syndrome, Congenital, 4c, Associated With Acetylcholine Receptor Deficiency,Disease Of Mental Health,Schizophrenia 1,Dyskeratosis Congenita, Autosomal Recessive 2,Down Syndrome,Smith-Mccort Dysplasia 1 |
5y1z_b | Q16643 | ENSG00000113758 | DBN1 | 99.90 | 1.20E-28 | 8.30E-33 | 156.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
YLL050C | COF1 | SGDID:S000003973 | GMFG |
Glia maturation factor gamma (GMF-gamma) |
Homo sapiens | 3l50_a | O60234 | ENSG00000130755 | GMFG | 99.90 | 1.00E-32 | 6.90E-37 | 174.90 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | ||
YLL050C | COF1 | SGDID:S000003973 | Gmfg |
Glia maturation factor gamma (GMF-gamma) |
Mus musculus | 1wfs_a | Q9ERL7 | 99.90 | 2.20E-32 | 1.50E-36 | 176.40 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | ||||
YLL050C | COF1 | SGDID:S000003973 | unc-60 C38C3.5 |
Actin-depolymerizing factor 2, isoform c (Uncoordinated protein 60) |
Caenorhabditis elegans | 2lxx_a | Q07749 | 99.90 | 3.60E-29 | 2.50E-33 | 161.20 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | ||||
YLL050C | COF1 | SGDID:S000003973 | SSRG_00151 |
SSRG_00151 |
Streptomyces griseoflavus | 5ivu_a | D9XKI5 | 99.90 | 9.60E-32 | 6.60E-36 | 171.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YLL050C | COF1 | SGDID:S000003973 | CELE_Y50D7A.10 Y50D7A.10 |
CELE_Y50D7A.10 Y50D7A.10 |
Caenorhabditis elegans | 5ynr_a | Q8IAA5 | 99.90 | 1.00E-31 | 7.20E-36 | 171.10 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | ||||
YLL050C | COF1 | SGDID:S000003973 | CADF1 |
Cofilin/actin-depolymerizing factor homolog 1 (PfADF1) |
Plasmodium falciparum | 3q2b_a | P86292 | 99.90 | 4.60E-28 | 3.10E-32 | 151.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YLL050C | COF1 | SGDID:S000003973 | DSTN DSN |
Destrin (Actin-depolymerizing factor) (ADF) |
Sus scrofa | 1ak7_a | P60982 | 100.00 | 3.50E-36 | 2.30E-40 | 197.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YLL050C | COF1 | SGDID:S000003973 | Tb927.3.5180 |
Tb927.3.5180 |
Trypanosoma brucei | 2lj8_a | Q580V7 | 99.90 | 5.80E-32 | 3.90E-36 | 173.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YLL050C | COF1 | SGDID:S000003973 | tsr Cadf CG4254 |
Cofilin/actin-depolymerizing factor homolog (Protein D61) (Protein twinstar) |
Drosophila melanogaster | 2mv2_a | P45594 | 99.90 | 4.70E-30 | 3.20E-34 | 164.80 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | ||||
YLL050C | COF1 | SGDID:S000003973 | Actin severing and dynamics regulatory protein |
Actin severing and dynamics regulatory protein |
Leishmania donovani | 2kvk_a | Q2QKR1 | 99.90 | 3.70E-31 | 2.50E-35 | 169.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YLL050C | COF1 | SGDID:S000003973 | ABP1 YCR088W YCR88W |
Actin-binding protein |
Saccharomyces cerevisiae | 1hqz_9 | P15891 | 99.90 | 4.10E-30 | 2.80E-34 | 163.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YLL050C | COF1 | SGDID:S000003973 | DBNL CMAP SH3P7 PP5423 |
Drebrin-like protein (Cervical SH3P7) (Cervical mucin-associated protein) (Drebrin-F) (HPK1-interacting protein of 55 kDa) (HIP-55) (SH3 domain-containing protein 7) |
Homo sapiens | Glycogen Storage Disease,Cardiomyopathy, Dilated, 1p,Encephalopathy, Progressive, Early-Onset, With Episodic Rhabdomyolysis,Glycogen Storage Disease X |
1x67_a | Q9UJU6 | ENSG00000136279 | DBNL | 99.90 | 1.70E-30 | 1.20E-34 | 166.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
YLL050C | COF1 | SGDID:S000003973 | COTL1 CLP |
Coactosin-like protein |
Homo sapiens | Dysbaric Osteonecrosis,Clivus Chordoma,Churg-Strauss Syndrome,Bleeding Disorder, Platelet-Type, 8,Lung Cancer |
1t3y_a | Q14019 | ENSG00000103187 | COTL1 | 99.90 | 5.20E-29 | 3.60E-33 | 158.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |