Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
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YLR035C | MLH2 | SGDID:S000004025 | MLH1 COCA2 |
DNA mismatch repair protein Mlh1 (MutL protein homolog 1) |
Homo sapiens | Spindle Cell Intraocular Melanoma,Duodenum Disease,Skin Melanoma,Uterine Body Mixed Cancer,Endocrine Gland Cancer,Endometrial Cancer,Richter'S Syndrome,Lung Cancer Susceptibility 3,Cowden Syndrome,Endometrial Hyperplasia,Muir-Torre Syndrome,Adenoma,Cowden Syndrome 1,Rectum Cancer,Rectum Adenocarcinoma,Bilateral Breast Cancer,Uterine Corpus Cancer,Bile Duct Cancer,Intestinal Benign Neoplasm,Ascending Colon Cancer,Intracranial Meningioma,46,Xy Disorder Of Sexual Development Due To Dihydrotestosterone Backdoor Pathway Biosynthesis Defect,Hereditary Nonpolyposis Colon Cancer,Familial Colorectal Cancer,Neurofibromatosis, Type I,Colon Adenocarcinoma,Colonic Benign Neoplasm,Sebaceous Adenocarcinoma,Rectum Signet Ring Adenocarcinoma,Small Intestine Adenocarcinoma,Inherited Cancer-Predisposing Syndrome,Hereditary Mixed Polyposis Syndrome,Basal Cell Carcinoma,Hematologic Cancer,Atypical Polypoid Adenomyoma,Adenomyoma,Transverse Colon Cancer,Mismatch Repair Cancer Syndrome,Sebaceous Adenoma,Transitional Cell Carcinoma,Duodenum Cancer,Infertility,Dysplastic Nevus Syndrome,Bladder Cancer,Small Intestine Cancer,Endometrial Adenocarcinoma,Extrahepatic Bile Duct Adenoma,Ulcerative Colitis,Monophasic Synovial Sarcoma,Anal Squamous Cell Carcinoma,Ovarian Cancer,Adenocarcinoma,Neurofibromatosis,Microinvasive Gastric Cancer,Jejunal Cancer,Female Reproductive Endometrioid Cancer,Mucinous Adenocarcinoma,Adenosquamous Colon Carcinoma,Breast Cancer,Squamous Cell Carcinoma, Head And Neck,Hereditary Breast Ovarian Cancer Syndrome,Lower Lip Cancer,Anaplastic Astrocytoma,Colorectal Cancer,Mismatch Repair Cancer Syndrome 1,Sebaceous Gland Neoplasm,Gallbladder Cancer,Colorectal Cancer, Hereditary Nonpolyposis, Type 2,Endometrioid Ovary Carcinoma,Duodenum Adenocarcinoma,Keratoacanthoma,Skin Benign Neoplasm,Oligodendroglioma,Renal Pelvis Transitional Cell Carcinoma,Rhabdomyosarcoma,Biliary Tract Cancer,Werner Syndrome,Juvenile Polyposis Syndrome,Xeroderma Pigmentosum, Variant Type,Fanconi Anemia, Complementation Group A,Skin Carcinoma,Gastric Cancer,Lymphangioma,Lynch Syndrome I,Friedreich Ataxia,Signet Ring Cell Adenocarcinoma,Cecum Carcinoma,Contractures, Pterygia, And Spondylocarpotarsal Fusion Syndrome 1a,Gastric Adenocarcinoma,Cervical Squamous Cell Carcinoma,Breast-Ovarian Cancer, Familial 1,Lynch Syndrome,Familial Adenomatous Polyposis,Colorectal Cancer 2,Esophageal Cancer,Inflammatory Bowel Disease,Gastrointestinal System Benign Neoplasm,Gastric Cancer, Hereditary Diffuse,Alveolar Soft Part Sarcoma,Tumor Predisposition Syndrome,Colorectal Cancer, Hereditary Nonpolyposis, Type 6,Autosomal Genetic Disease,Colorectal Cancer, Hereditary Nonpolyposis, Type 4,Colorectal Cancer, Hereditary Nonpolyposis, Type 5,Ureter, Cancer Of,Colorectal Adenoma,Colorectal Adenocarcinoma,Villous Adenoma,Cutaneous Telangiectasia And Cancer Syndrome, Familial,Appendix Carcinoid Tumor,Jejunal Adenocarcinoma,Ovarian Clear Cell Carcinoma,Cell Type Benign Neoplasm,Uterine Benign Neoplasm,Colitis,Li-Fraumeni Syndrome,Anal Fistula,Melanoma, Cutaneous Malignant 1,Autosomal Dominant Non-Syndromic Intellectual Disability 8,Lung Cancer,Pancreatic Cancer |
4p7a_a | P40692 | ENSG00000076242 | MLH1 | 99.90 | 2.60E-30 | 2.40E-34 | 273.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
YLR035C | MLH2 | SGDID:S000004025 | PMS1 YNL082W N2317 |
DNA mismatch repair protein PMS1 (Postmeiotic segregation protein 1) |
Saccharomyces cerevisiae | 3h4l_b | P14242 | 99.90 | 3.20E-30 | 3.00E-34 | 272.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YLR035C | MLH2 | SGDID:S000004025 | PMS2 PMSL2 |
Mismatch repair endonuclease PMS2 (EC 3.1.-.-) (DNA mismatch repair protein PMS2) (PMS1 protein homolog 2) |
3.1.-.- | Homo sapiens | Spindle Cell Intraocular Melanoma,Duodenum Disease,Skin Melanoma,Cervical Adenosarcoma,Endometrial Cancer,Gastrointestinal Adenoma,Cowden Syndrome,Muir-Torre Syndrome,Chronic Congestive Splenomegaly,Cowden Syndrome 1,Rectum Adenocarcinoma,Uterine Corpus Cancer,T-Cell Non-Hodgkin Lymphoma,Oligoastrocytoma,Intestinal Benign Neoplasm,Optic Pathway Glioma,Esophageal Tuberculosis,Mismatch Repair Cancer Syndrome 4,46,Xy Disorder Of Sexual Development Due To Dihydrotestosterone Backdoor Pathway Biosynthesis Defect,Hereditary Nonpolyposis Colon Cancer,Neurofibromatosis, Type I,Colon Adenocarcinoma,Colonic Benign Neoplasm,Sebaceous Adenocarcinoma,Rectum Signet Ring Adenocarcinoma,Small Intestine Adenocarcinoma,Pituitary Carcinoma,Inherited Cancer-Predisposing Syndrome,Hereditary Mixed Polyposis Syndrome,Bap1 Tumor Predisposition Syndrome,Transverse Colon Cancer,Mismatch Repair Cancer Syndrome,Sebaceous Adenoma,Duodenum Cancer,Dysplastic Nevus Syndrome,Rectosigmoid Cancer,Small Intestine Cancer,Brain Cancer,Extrahepatic Bile Duct Adenoma,Ovarian Cancer,Burkitt Lymphoma,Neurofibromatosis,Jejunal Cancer,Female Reproductive Endometrioid Cancer,Adenosquamous Colon Carcinoma,Breast Cancer,Transcobalamin Ii Deficiency,Hereditary Breast Ovarian Cancer Syndrome,Anaplastic Astrocytoma,Colorectal Cancer,Mismatch Repair Cancer Syndrome 1,Sebaceous Gland Neoplasm,Duodenum Adenocarcinoma,Fallopian Tube Endometrioid Adenocarcinoma,Anaplastic Ganglioglioma,Anaplastic Oligoastrocytoma,Oligodendroglioma,Familial Hyperaldosteronism,Rhabdomyosarcoma,Pulmonary Valve Insufficiency,Juvenile Polyposis Syndrome,Esophagus Sarcoma,Fanconi Anemia, Complementation Group A,Respiratory Failure,Skin Carcinoma,Lynch Syndrome I,Prostate Cancer,Contractures, Pterygia, And Spondylocarpotarsal Fusion Syndrome 1a,Pulmonary Hypertension, Primary, 1,Lynch Syndrome,Gastric Cancer, Hereditary Diffuse,Tumor Predisposition Syndrome,Colorectal Cancer, Hereditary Nonpolyposis, Type 6,Autosomal Genetic Disease,Colorectal Cancer, Hereditary Nonpolyposis, Type 4,Colorectal Cancer, Hereditary Nonpolyposis, Type 5,Periampullary Adenoma,Colorectal Adenocarcinoma,Cutaneous Telangiectasia And Cancer Syndrome, Familial,Appendix Carcinoid Tumor,Jejunal Adenocarcinoma,Wilms Tumor 1,Lymphoma,Li-Fraumeni Syndrome |
1h7s_a | P54278 | ENSG00000122512 | PMS2 | 99.90 | 2.50E-30 | 2.40E-34 | 274.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YLR035C | MLH2 | SGDID:S000004025 | mutL b4170 JW4128 |
DNA mismatch repair protein MutL |
Escherichia coli | 1b63_a | P23367 | 99.90 | 3.00E-33 | 2.70E-37 | 294.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | ||||
YLR035C | MLH2 | SGDID:S000004025 | mutL aq_1578 |
DNA mismatch repair protein MutL |
Aquifex aeolicus | 5x9y_a | O67518 | 99.90 | 6.60E-27 | 6.20E-31 | 241.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |