Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
YLR174W | IDP2 | SGDID:S000004164 | IDH3G |
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial (Isocitric dehydrogenase subunit gamma) (NAD(+)-specific ICDH subunit gamma) |
Homo sapiens | Inhibited Female Orgasm,Intracranial Chondrosarcoma,Juxtacortical Chondroma,D-2-Hydroxyglutaric Aciduria 2,Lubs X-Linked Mental Retardation Syndrome,2-Hydroxyglutaric Aciduria,Multiple Enchondromatosis, Maffucci Type,D-2-Hydroxyglutaric Aciduria 1 |
5grf_b | P51553 | ENSG00000067829 | IDH3G | 100.00 | 5.30E-76 | 3.70E-80 | 554.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
YLR174W | IDP2 | SGDID:S000004164 | APE_0689.1 |
APE_0689.1 |
1.1.1.42 | Aeropyrum pernix | 1tyo_b | Q9YE81 | 100.00 | 3.20E-77 | 2.20E-81 | 575.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | leuB |
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH) |
1.1.1.85 | Acidithiobacillus ferrooxidans | 1a05_a | Q56268 | 100.00 | 8.60E-88 | 5.90E-92 | 632.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | leuB |
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH) |
1.1.1.85 | Bacillus coagulans | 1v5b_b | P12010 | 100.00 | 7.70E-76 | 5.40E-80 | 558.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | leuB |
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH) |
1.1.1.85 | Acidithiobacillus ferrooxidans | 1a05_b | Q56268 | 100.00 | 1.50E-78 | 1.10E-82 | 574.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | IDH2 |
Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (ICD-M) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) |
1.1.1.42 | Homo sapiens | Adult Hepatocellular Carcinoma,Retinitis Pigmentosa,Brain Stem Glioma,Chondrosarcoma,Plasma Cell Neoplasm,Connective Tissue Cancer,Bone Sarcoma,Gemistocytic Astrocytoma,Protoplasmic Astrocytoma,Oligoastrocytoma,Anaplastic Oligodendroglioma,Sinonasal Undifferentiated Carcinoma,Low Grade Glioma,Essential Thrombocythemia,Biliary Tract Disease,Enchondroma,Adult Brain Stem Glioma,Diffuse Astrocytoma,Angioimmunoblastic T-Cell Lymphoma,Bile Duct Adenocarcinoma,Intracranial Chondrosarcoma,Intrahepatic Cholangiocarcinoma,Mixed Oligodendroglioma-Astrocytoma,Glioma,Leukemia, Acute Myeloid,Spindle Cell Hemangioma,Bone Marrow Cancer,Hemangioma,Mixed Glioma,Juxtacortical Chondroma,Combined D-2- And L-2-Hydroxyglutaric Aciduria,Brain Cancer,Enchondromatosis, Multiple, Ollier Type,Myeloid Leukemia,Glioblastoma,Squamous Cell Carcinoma, Head And Neck,Malignant Astrocytoma,High Grade Glioma,Gliosarcoma,Giant Cell Glioblastoma,Adult Astrocytic Tumour,Anaplastic Astrocytoma,Colorectal Cancer,Cytogenetically Normal Acute Myeloid Leukemia,Hepatocellular Carcinoma,Anaplastic Oligoastrocytoma,Periosteal Chondrosarcoma,Clear Cell Chondrosarcoma,Oligodendroglioma,Childhood Oligodendroglioma,Adult Oligodendroglioma,Pheochromocytoma,Chondroblastic Osteosarcoma,D-2-Hydroxyglutaric Aciduria 2,Systemic Mastocytosis,Cholangiocarcinoma,Central Nervous System Cancer,L-2-Hydroxyglutaric Aciduria,2-Hydroxyglutaric Aciduria,Myelodysplastic Syndrome,Glioma Susceptibility 1,Mature T-Cell And Nk-Cell Lymphoma,Multiple Enchondromatosis, Maffucci Type,Brain Glioma,Li-Fraumeni Syndrome,Myelofibrosis,Myeloma, Multiple,Spinal Disease,Childhood Acute Myeloid Leukemia,Lung Cancer,D-2-Hydroxyglutaric Aciduria 1,Polycythemia Vera |
4ja8_a | P48735 | ENSG00000182054 | IDH2 | 100.00 | 1.50E-83 | 1.00E-87 | 617.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YLR174W | IDP2 | SGDID:S000004164 | leuB Cj1718c |
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH) |
1.1.1.85 | Campylobacter jejuni | 3udu_b | Q9PLW0 | 100.00 | 1.00E-78 | 7.00E-83 | 575.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | IDH1 PICD |
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH) (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) |
1.1.1.42 | Homo sapiens | Adult Hepatocellular Carcinoma,Supratentorial Cancer,Skin Melanoma,Cerebral Convexity Meningioma,Gliomatosis Cerebri,Bile Duct Disease,Brain Stem Glioma,Brain Stem Cancer,Cerebellum Cancer,Lung Cancer Susceptibility 3,Childhood Brain Stem Glioma,Adenoid Cystic Carcinoma,Chondrosarcoma,Bone Cancer,Suppression Of Tumorigenicity 12,Melanoma,Plasma Cell Neoplasm,Internal Auditory Canal Lipoma,Metaphyseal Enchondromatosis With D-2-Hydroxyglutaric Aciduria,Connective Tissue Cancer,Bone Sarcoma,Frontal Lobe Neoplasm,Juvenile Pilocytic Astrocytoma,Childhood Pilocytic Astrocytoma,Diffuse Midline Glioma, H3 K27m-Mutant,Gemistocytic Astrocytoma,Mucinous Intrahepatic Cholangiocarcinoma,Atypical Teratoid Rhabdoid Tumor,Temporal Lobe Neoplasm,Low Grade Glioma,Essential Thrombocythemia,Astroblastoma,Biliary Tract Disease,Myeloproliferative Neoplasm,Enchondroma,Infratentorial Cancer,Supratentorial Primitive Neuroectodermal Tumor,Adult Brain Stem Glioma,Benign Ependymoma,Pilomyxoid Astrocytoma,Cerebellar Astrocytoma,Pilocytic Astrocytoma,Pleomorphic Xanthoastrocytoma,Pilocytic Astrocytoma Of Cerebellum,Gliofibroma,Diffuse Astrocytoma,Spinal Cord Astrocytoma,Bile Duct Adenocarcinoma,Klatskin'S Tumor,Intracranial Chondrosarcoma,Intrahepatic Cholangiocarcinoma,Mixed Oligodendroglioma-Astrocytoma,Glioma,Frontal Convexity Meningioma,Leukemia, Acute Myeloid,Spindle Cell Hemangioma,Bone Marrow Cancer,Hemangioma,High Grade Ependymoma,Angiocentric Glioma,High-Grade Astrocytoma,Low-Grade Astrocytoma,Mixed Glioma,Extraventricular Neurocytoma,Juxtacortical Chondroma,Dysembryoplastic Neuroepithelial Tumor,Brain Cancer,Enchondromatosis, Multiple, Ollier Type,Laryngeal Neuroendocrine Tumor,Clear Cell Ependymoma,Myeloid Leukemia,Spinal Cancer,Breast Cancer,Glioblastoma,Malignant Astrocytoma,High Grade Glioma,Gliosarcoma,Giant Cell Glioblastoma,Adult Astrocytic Tumour,Anaplastic Astrocytoma,Juvenile Astrocytoma,Colorectal Cancer,Nervous System Cancer,Cytogenetically Normal Acute Myeloid Leukemia,Hepatocellular Carcinoma,Periosteal Chondrosarcoma,Oligodendroglioma,Childhood Oligodendroglioma,Spinal Cord Oligodendroglioma,Spinal Cord Glioma,Adult Oligodendroglioma,Chondroblastic Osteosarcoma,Breast Adenocarcinoma,Cholangiocarcinoma,Cerebral Ventricle Cancer,Central Nervous System Cancer,Alpha-Thalassemia,Cerebrum Cancer,Adult Central Nervous System Primitive Neuroectodermal Neoplasm,Bladder Urothelial Carcinoma,L-2-Hydroxyglutaric Aciduria,2-Hydroxyglutaric Aciduria,Myelodysplastic Syndrome,Glioma Susceptibility 1,Multiple Enchondromatosis, Maffucci Type,Uterine Corpus Endometrial Carcinoma,Central Nervous System Benign Neoplasm,Brain Glioma,Li-Fraumeni Syndrome,Myelofibrosis,Myeloma, Multiple,Medulloblastoma,Spinal Disease,Childhood Acute Myeloid Leukemia,Lung Cancer,D-2-Hydroxyglutaric Aciduria 1,Polycythemia Vera |
1t0l_c | O75874 | ENSG00000138413 | IDH1 | 100.00 | 4.80E-82 | 3.30E-86 | 608.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YLR174W | IDP2 | SGDID:S000004164 | leuB Saci_0600 |
leuB Saci_0600 |
1.1.1.85 | Sulfolobus acidocaldarius | 4y1p_a | Q4JB37 | 100.00 | 2.90E-79 | 2.00E-83 | 573.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | icd TTHA1535 |
Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) |
1.1.1.42 | Thermus thermophilus | 2d1c_b | P33197 | 100.00 | 1.10E-81 | 7.60E-86 | 608.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | icd |
icd |
1.1.1.42 | Acidithiobacillus thiooxidans | 2d4v_b | Q8GAX0 | 100.00 | 3.00E-76 | 2.10E-80 | 566.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | leuB BTH_II0674 |
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH) |
1.1.1.85 | Burkholderia thailandensis | 4iwh_a | Q2T7H6 | 100.00 | 3.20E-78 | 2.20E-82 | 572.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | lys12 SPAC31G5.04 |
Homoisocitrate dehydrogenase (HICDH) (EC 1.1.1.87) |
1.1.1.87 | Schizosaccharomyces pombe | 3ty3_a | O14104 | 100.00 | 2.20E-78 | 1.50E-82 | 572.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | IDH1 YNL037C N2690 |
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) |
1.1.1.41 | Saccharomyces cerevisiae | 3blx_e | P28834 | 100.00 | 1.70E-76 | 1.20E-80 | 558.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | DP0778 |
DP0778 |
1.1.1.42 | Desulfotalea psychrophila | 2uxq_b | Q6AQ66 | 100.00 | 2.20E-80 | 1.50E-84 | 596.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | IMDH2 IMD2 IMDH IPMDH2 At1g80560 T21F11.11 |
3-isopropylmalate dehydrogenase 2, chloroplastic (3-IPM-DH 2) (AtIMDH2) (AtIMDH3) (IMDH 2) (EC 1.1.1.85) (Beta-IPM dehydrogenase 2) (Isopropylmalate dehydrogenase 2) (AtIMD2) |
1.1.1.85 | Arabidopsis thaliana | 5j32_a | P93832 | 100.00 | 4.20E-79 | 2.90E-83 | 583.60 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | Cthe_0285 |
Cthe_0285 |
1.1.1.42 | Hungateiclostridium thermocellum | 4aou_a | A3DC45 | 100.00 | 5.10E-80 | 3.50E-84 | 592.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | IDP1 YDL066W |
Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) |
1.1.1.42 | Saccharomyces cerevisiae | 2qfw_d | P21954 | 100.00 | 4.60E-84 | 3.20E-88 | 623.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | TK0280 |
TK0280 |
Thermococcus kodakarensis | 5hn3_a | Q5JFV8 | 100.00 | 7.20E-78 | 5.00E-82 | 564.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YLR174W | IDP2 | SGDID:S000004164 | IDH3A |
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit alpha) (NAD(+)-specific ICDH subunit alpha) |
1.1.1.41 | Homo sapiens | Retinitis Pigmentosa,Inhibited Female Orgasm,Cone-Rod Dystrophy 2,2-Hydroxyglutaric Aciduria,Infantile Cerebellar-Retinal Degeneration,Mitochondrial Complex I Deficiency, Nuclear Type 1,Retinitis Pigmentosa 90,D-2-Hydroxyglutaric Aciduria 1 |
5gri_a | P50213 | ENSG00000166411 | IDH3A | 100.00 | 8.40E-79 | 5.80E-83 | 571.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YLR174W | IDP2 | SGDID:S000004164 | TM_1148 |
TM_1148 |
1.1.1.42 | Thermotoga maritima | 1zor_a | Q9X0N2 | 100.00 | 1.20E-82 | 8.50E-87 | 611.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | icd icdA icdE b1136 JW1122 |
Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) |
1.1.1.42 | Escherichia coli | 1p8f_a | P08200 | 100.00 | 7.80E-79 | 5.40E-83 | 584.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
YLR174W | IDP2 | SGDID:S000004164 | TTUC |
Tartrate dehydrogenase/decarboxylase (TDH) (EC 1.1.1.93) (EC 4.1.1.73) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) |
1.1.1.83,1.1.1.93,4.1.1.73 | Pseudomonas putida | 3flk_a | Q51945 | 100.00 | 1.50E-77 | 1.10E-81 | 569.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | icd citC BSU29130 |
Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) |
1.1.1.42 | Bacillus subtilis | 1hqs_b | P39126 | 100.00 | 1.40E-77 | 9.30E-82 | 573.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | idh ST2166 STK_21660 |
idh ST2166 STK_21660 |
1.1.1.42 | Sulfurisphaera tokodaii | 2e0c_a | Q96YK6 | 100.00 | 7.90E-77 | 5.40E-81 | 569.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | icd AF_0647 |
Isocitrate dehydrogenase [NADP] (IDH) (EC 1.1.1.42) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) |
1.1.1.42 | Archaeoglobus fulgidus | 2iv0_b | O29610 | 100.00 | 1.90E-78 | 1.30E-82 | 579.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | icd BURPS1710b_1108 |
icd BURPS1710b_1108 |
1.1.1.42 | Burkholderia pseudomallei | 3dms_a | Q3JV82 | 100.00 | 5.10E-76 | 3.50E-80 | 565.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | leuB b0073 JW5807 |
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH) |
1.1.1.85 | Escherichia coli | 1cm7_b | P30125 | 100.00 | 1.70E-78 | 1.20E-82 | 575.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
YLR174W | IDP2 | SGDID:S000004164 | hicd hdh hicdh TT_C1012 |
Homoisocitrate dehydrogenase (HICDH) (EC 1.1.1.87) |
1.1.1.87 | Thermus thermophilus | 1x0l_a | Q72IW9 | 100.00 | 4.60E-81 | 3.20E-85 | 585.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | leuB Rv2995c MTV012.09 |
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH) |
1.1.1.85 | Mycobacterium tuberculosis | 1w0d_b | P9WKK9 | 100.00 | 6.90E-78 | 4.80E-82 | 565.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | leuB SHEWBE_0188 |
leuB SHEWBE_0188 |
1.1.1.85 | Shewanella benthica | 3vmk_b | D2YZL2 | 100.00 | 1.10E-77 | 7.50E-82 | 569.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | IDH2 YOR136W O3326 YOR3326W |
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) |
1.1.1.41 | Saccharomyces cerevisiae | 3blv_h | P28241 | 100.00 | 3.40E-78 | 2.30E-82 | 569.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YLR174W | IDP2 | SGDID:S000004164 | leuB TTHA1230 |
3-isopropylmalate dehydrogenase (EC 1.1.1.85) (3-IPM-DH) (Beta-IPM dehydrogenase) (IMDH) |
1.1.1.85 | Thermus thermophilus | 2y3z_a | Q5SIY4 | 100.00 | 2.70E-80 | 1.90E-84 | 586.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |