Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
YML106W | URA5 | SGDID:S000004574 | apt b0469 JW0458 |
Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7) |
2.4.2.7 | Escherichia coli | 2dy0_b | P69503 | 99.10 | 7.10E-15 | 4.70E-19 | 105.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
YML106W | URA5 | SGDID:S000004574 | prs SSO1045 |
Ribose-phosphate pyrophosphokinase (RPPK) (EC 2.7.6.1) (5-phospho-D-ribosyl alpha-1-diphosphate) (Phosphoribosyl diphosphate synthase) (Phosphoribosyl pyrophosphate synthase) (P-Rib-PP synthase) (PRPP synthase) (PRPPase) |
2.7.6.1 | Saccharolobus solfataricus | 4twb_f | Q97Z86 | 99.10 | 2.30E-14 | 1.50E-18 | 109.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | E8M63_03605 NCTC13805_02457 WHOF_00431 WHOF_02526C |
E8M63_03605 NCTC13805_02457 WHOF_00431 WHOF_02526C |
Neisseria gonorrhoeae | 5vog_a | A0A1D3HIA2 | 99.10 | 2.40E-14 | 1.60E-18 | 102.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YML106W | URA5 | SGDID:S000004574 | HGPRT |
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8) |
2.4.2.8 | Schistosoma mansoni | 5ipf_a | P09383 | 99.10 | 1.20E-14 | 7.70E-19 | 108.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | pyrE FTT_0437c |
pyrE FTT_0437c |
2.4.2.10 | Francisella tularensis | 3mjd_a | Q5NHL5 | 99.90 | 8.80E-27 | 5.80E-31 | 173.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | pyrE HP_1257 |
Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10) |
2.4.2.10 | Helicobacter pylori | 4paw_a | P56162 | 99.70 | 5.60E-21 | 3.70E-25 | 141.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | pyrE SMU_1221 |
Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10) |
2.4.2.10 | Streptococcus mutans | 3dez_a | Q8DTV2 | 99.80 | 3.40E-26 | 2.30E-30 | 171.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | PRPSAP2 |
Phosphoribosyl pyrophosphate synthase-associated protein 2 (PRPP synthase-associated protein 2) (41 kDa phosphoribosypyrophosphate synthetase-associated protein) (PAP41) |
Homo sapiens | Brittle Bone Disorder,X-Linked Nonsyndromic Deafness,Deafness, X-Linked 1,Charcot-Marie-Tooth Disease, X-Linked Recessive, 5 |
2ji4_a | O60256 | ENSG00000141127 | PRPSAP2 | 99.20 | 4.80E-15 | 3.10E-19 | 117.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
YML106W | URA5 | SGDID:S000004574 | LDHU3_26.0190 |
LDHU3_26.0190 |
2.4.2.7 | Leishmania donovani | 1qcd_a | Q27679 | 99.50 | 3.50E-18 | 2.30E-22 | 127.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | xpt BSU22070 |
Xanthine phosphoribosyltransferase (XPRTase) (EC 2.4.2.22) |
2.4.2.22 | Bacillus subtilis | 1y0b_d | P42085 | 99.10 | 6.30E-15 | 4.10E-19 | 106.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | pyrE DIP2097 |
pyrE DIP2097 |
2.4.2.10 | Corynebacterium diphtheriae | 2p1z_b | Q6NF12 | 99.70 | 8.80E-23 | 5.80E-27 | 146.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | PRPSAP1 |
Phosphoribosyl pyrophosphate synthase-associated protein 1 (PRPP synthase-associated protein 1) (39 kDa phosphoribosypyrophosphate synthase-associated protein) (PAP39) |
Homo sapiens | Hepatocellular Carcinoma,Bardet-Biedl Syndrome 7,X-Linked Nonsyndromic Deafness,Arts Syndrome,Deafness, X-Linked 1,Charcot-Marie-Tooth Disease, X-Linked Recessive, 5 |
2c4k_c | Q14558 | ENSG00000161542 | PRPSAP1 | 99.10 | 8.60E-15 | 5.60E-19 | 115.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
YML106W | URA5 | SGDID:S000004574 | pyrE APE_2349.1 |
Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10) |
2.4.2.10 | Aeropyrum pernix | 2yzk_a | Q9Y9D8 | 99.70 | 1.10E-22 | 7.30E-27 | 145.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | apt Rmar_0813 |
apt Rmar_0813 |
2.4.2.7 | Rhodothermus marinus | 4m0k_a | D0MGF4 | 99.20 | 1.00E-15 | 6.70E-20 | 110.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | URA5 PYR5 YML106W YM8339.13 |
Orotate phosphoribosyltransferase 1 (OPRT 1) (OPRTase 1) (EC 2.4.2.10) |
2.4.2.10 | Saccharomyces cerevisiae | 2ps1_a | P13298 | 99.90 | 7.10E-31 | 4.70E-35 | 195.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | prs BPSL0521 |
Ribose-phosphate pyrophosphokinase (RPPK) (EC 2.7.6.1) (5-phospho-D-ribosyl alpha-1-diphosphate) (Phosphoribosyl diphosphate synthase) (Phosphoribosyl pyrophosphate synthase) (P-Rib-PP synthase) (PRPP synthase) (PRPPase) |
2.7.6.1 | Burkholderia pseudomallei | 3dah_c | Q63XL8 | 99.20 | 1.70E-15 | 1.10E-19 | 117.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | pyrE umpA Rv0382c MTV036.17c |
Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10) |
2.4.2.10 | Mycobacterium tuberculosis | 5hkl_b | P9WHK9 | 99.80 | 2.90E-23 | 1.90E-27 | 150.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | pyrE SPy_0901 M5005_Spy0704 |
Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10) |
2.4.2.10 | Streptococcus pyogenes | 2aee_a | Q9A076 | 99.90 | 1.40E-26 | 9.30E-31 | 170.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | apt Teth39_1027 |
Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7) |
2.4.2.7 | Thermoanaerobacter pseudethanolicus | 4lza_b | B0K969 | 99.20 | 4.20E-15 | 2.70E-19 | 107.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | pyrE b3642 JW3617 |
Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10) |
2.4.2.10 | Escherichia coli | 1oro_a | P0A7E3 | 99.90 | 1.20E-27 | 8.00E-32 | 176.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
YML106W | URA5 | SGDID:S000004574 | apt FTT_0078 |
Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7) |
2.4.2.7 | Francisella tularensis | 5yw2_b | Q5NII9 | 99.10 | 5.70E-15 | 3.70E-19 | 104.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | PRPS1 |
Ribose-phosphate pyrophosphokinase 1 (EC 2.7.6.1) (PPRibP) (Phosphoribosyl pyrophosphate synthase I) (PRS-I) |
2.7.6.1 | Homo sapiens | Charcot-Marie-Tooth Disease Type 5,Retinitis Pigmentosa,Hyperuricemia,Purine-Pyrimidine Metabolic Disorder,Neuromuscular Disease,X-Linked Intellectual Disability-Limb Spasticity-Retinal Dystrophy-Diabetes Insipidus Syndrome,Charcot-Marie-Tooth Disease X-Linked Recessive 4,Charcot-Marie-Tooth Neuropathy X Type 5,Dfnx1 Nonsyndromic Hearing Loss And Deafness,Sensorineural Hearing Loss,Hereditary Hearing Loss And Deafness,Fundus Dystrophy,Gout,Neuropathy,Charcot-Marie-Tooth Disease, Type 4b3,Charcot-Marie-Tooth Disease,X-Linked Charcot-Marie-Tooth Disease,X-Linked Non-Syndromic Sensorineural Deafness Type Dfn,Nonsyndromic Hearing Loss,Tooth Disease,Deafness, X-Linked 3,Deafness, X-Linked 4,Hutchinson-Gilford Progeria Syndrome,Lesch-Nyhan Syndrome,Deafness, X-Linked 5, With Peripheral Neuropathy,Phosphoribosylpyrophosphate Synthetase Superactivity,Neuropathy, Congenital Hypomyelinating, 1, Autosomal Recessive,Charcot-Marie-Tooth Disease Type X,X-Linked Nonsyndromic Deafness,Charcot-Marie-Tooth Disease, X-Linked Dominant, 6,Deafness, X-Linked 6,Ataxia, Combined Cerebellar And Peripheral, With Hearing Loss And Diabetes Mellitus,Nephrolithiasis, Uric Acid,Brown-Vialetto-Van Laere Syndrome,Arts Syndrome,Charcot-Marie-Tooth Disease, X-Linked Recessive, 2,Syndromic Intellectual Disability,Deafness, X-Linked 2,Deafness, X-Linked 1,Opitz-Kaveggia Syndrome,Syndromic X-Linked Intellectual Disability,Charcot-Marie-Tooth Disease, X-Linked Recessive, 5,Optic Atrophy, Hearing Loss, And Peripheral Neuropathy, Autosomal Recessive |
3s5j_b | P60891 | ENSG00000147224 | PRPS1 | 99.20 | 4.70E-15 | 3.10E-19 | 115.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YML106W | URA5 | SGDID:S000004574 | oprt |
oprt |
2.4.2.10 | Plasmodium falciparum | 4fym_c | Q8N0R1 | 99.70 | 6.40E-22 | 4.20E-26 | 150.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | APRT |
Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7) |
2.4.2.7 | Homo sapiens | Purine-Pyrimidine Metabolic Disorder,Urolithiasis,Dihydroxyadeninuria,Morquio Syndrome,Congenital Muscular Dystrophy-Dystroglycanopathy Type A11,Mucopolysaccharidosis-Plus Syndrome,Cystinuria,Mucopolysaccharidosis Iv,Gout,Purine Nucleoside Phosphorylase Deficiency,Nephrolithiasis, Calcium Oxalate,Interstitial Nephritis,Nephrolithiasis,Hereditary Xanthinuria,Ureterolithiasis,Retinitis Pigmentosa 56,Lesch-Nyhan Syndrome,Lynch Syndrome,Phosphoribosylpyrophosphate Synthetase Superactivity,Arts Syndrome,Adenine Phosphoribosyltransferase Deficiency,Xanthinuria,Molybdenum Cofactor Deficiency, Complementation Group A,Mucopolysaccharidosis, Type Iva |
6fch_a | P07741 | ENSG00000198931 | APRT | 99.20 | 1.90E-15 | 1.20E-19 | 107.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YML106W | URA5 | SGDID:S000004574 | Tb927.7.1780 |
Tb927.7.1780 |
2.4.2.7 | Trypanosoma brucei | 5vn4_a | Q57V32 | 99.30 | 1.10E-16 | 6.90E-21 | 119.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | APT1 YML022W |
Adenine phosphoribosyltransferase 1 (APRT 1) (EC 2.4.2.7) |
2.4.2.7 | Saccharomyces cerevisiae | 1g2q_b | P49435 | 99.10 | 2.60E-14 | 1.70E-18 | 102.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | pyrE BA_4021 GBAA_4021 BAS3733 |
Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10) |
2.4.2.10 | Bacillus anthracis | 3m3h_a | Q81WF6 | 99.80 | 5.20E-26 | 3.40E-30 | 169.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | LDBPK_160560 |
LDBPK_160560 |
2.4.2.10,4.1.1.23, | Leishmania donovani | 3qw4_c | E9BCQ9 | 99.80 | 8.70E-25 | 5.70E-29 | 177.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | HPRT |
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGPRT) (HGXPRT) (HGXPRTase) (EC 2.4.2.22) (EC 2.4.2.8) |
2.4.2.22,2.4.2.8, | Toxoplasma gondii | 1fsg_a | Q26997 | 99.20 | 9.70E-16 | 6.30E-20 | 113.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | prs BSU00510 |
Ribose-phosphate pyrophosphokinase (RPPK) (EC 2.7.6.1) (5-phospho-D-ribosyl alpha-1-diphosphate) (Phosphoribosyl diphosphate synthase) (Phosphoribosyl pyrophosphate synthase) (P-Rib-PP synthase) (PPRibP synthase) (PRPP synthase) (PRPPase) |
2.7.6.1 | Bacillus subtilis | 1dkr_b | P14193 | 99.20 | 4.50E-15 | 2.90E-19 | 114.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | apt YPTB0991 |
Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7) |
2.4.2.7 | Yersinia pseudotuberculosis | 5b6h_a | Q66DQ2 | 99.10 | 6.90E-15 | 4.50E-19 | 104.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | hpt hprT Rv3624c MTCY15C10.28 |
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8) |
2.4.2.8 | Mycobacterium tuberculosis | 4rhx_b | P9WHQ9 | 99.10 | 1.90E-14 | 1.30E-18 | 104.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | pyrE VC_0211 |
Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10) |
2.4.2.10 | Vibrio cholerae | 3n2l_d | Q9KVD5 | 99.90 | 1.10E-28 | 7.00E-33 | 184.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | pyrE BCAL0204 |
pyrE BCAL0204 |
2.4.2.10 | Burkholderia cenocepacia | 4ohc_b | B4E589 | 99.80 | 1.10E-24 | 7.50E-29 | 162.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YML106W | URA5 | SGDID:S000004574 | UMPS OK/SW-cl.21 |
Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10); Orotidine 5'-phosphate decarboxylase (ODC) (EC 4.1.1.23) (OMPdecase)] |
2.4.2.10,4.1.1.23, | Homo sapiens | Gastroesophageal Adenocarcinoma,Megaloblastic Anemia,Colorectal Cancer,Gastric Cancer,Arts Syndrome,Pyrimidine Metabolic Disorder,Adenine Phosphoribosyltransferase Deficiency,Charcot-Marie-Tooth Disease, X-Linked Recessive, 5,Orotic Aciduria,Postaxial Acrofacial Dysostosis |
2wns_a | P11172 | ENSG00000114491 | UMPS | 99.80 | 2.00E-26 | 1.30E-30 | 168.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YML106W | URA5 | SGDID:S000004574 | prs TTHA1637 |
prs TTHA1637 |
2.7.6.1 | Thermus thermophilus | 5t3o_b | Q5SHU3 | 99.20 | 5.00E-15 | 3.30E-19 | 113.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |