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Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
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YMR015C | ERG5 | SGDID:S000004617 | cyp17a2 |
cyp17a2 |
Danio rerio | 4r21_a | A7U483 | 100.00 | 1.30E-50 | 6.90E-55 | 382.50 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | ||||
YMR015C | ERG5 | SGDID:S000004617 | CYP11B1 S11BH |
Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid 11-beta-hydroxylase, CYP11B1) (EC 1.14.15.4) |
1.14.15.4 | Homo sapiens | Steroid Inherited Metabolic Disorder,Adrenal Rest Tumor,Adrenal Adenoma,Adenoma,Familial Glucocorticoid Deficiency,Syndromic Microphthalmia,Hyperaldosteronism, Familial, Type I,Conn'S Syndrome,Adrenal Gland Disease,Hypokalemia,Apparent Mineralocorticoid Excess,Carney Complex Variant,Familial Hyperaldosteronism,46,Xy Sex Reversal,46,Xy Sex Reversal 2,Liddle Syndrome 1,Achalasia-Addisonianism-Alacrima Syndrome,Adrenal Cortical Carcinoma,Functional Colonic Disease,Adrenal Carcinoma,Adrenal Cortex Disease,Asperger Syndrome,Microphthalmia, Syndromic 10,Adrenal Cortical Adenoma,Hypertension, Essential,Endocrine Organ Benign Neoplasm,Lipoid Congenital Adrenal Hyperplasia,Adrenal Hyperplasia, Congenital, Due To Steroid 11-Beta-Hydroxylase Deficiency,Corticosterone Methyloxidase Type I Deficiency,Primary Pigmented Nodular Adrenocortical Disease,Pseudohypoaldosteronism, Type I, Autosomal Recessive |
6m7x_b | P15538 | ENSG00000160882 | CYP11B1 | 100.00 | 9.50E-52 | 5.20E-56 | 389.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YMR015C | ERG5 | SGDID:S000004617 | CYP51A1 CYP51 |
Lanosterol 14-alpha demethylase (LDM) (EC 1.14.14.154) (CYPLI) (Cytochrome P450 51A1) (Cytochrome P450-14DM) (Cytochrome P45014DM) (Cytochrome P450LI) (Sterol 14-alpha demethylase) |
1.14.14.154 | Homo sapiens | Dermatophytosis,Fungal Meningitis,Tinea Cruris,Chagas Disease,Amyotrophic Lateral Sclerosis 1,Tinea Pedis,Opportunistic Mycosis,Sveinsson Chorioretinal Atrophy,Mucormycosis,Eumycotic Mycetoma,Sleeping Sickness,Esophageal Candidiasis,Parasitic Protozoa Infectious Disease,Coccidioidomycosis,Neuroaspergillosis,Congenital Cataract-Severe Neonatal Hepatopathy-Global Developmental Delay Syndrome,Phaeohyphomycosis,Candidiasis,Dermatomycosis,Fungal Infectious Disease,Invasive Aspergillosis,Pulmonary Aspergilloma,Primary Amebic Meningoencephalitis,Conidiobolomycosis,Fusariosis,Primary Systemic Mycosis,Antley-Bixler Syndrome,Dehydrated Hereditary Stomatocytosis 1 With Or Without Pseudohyperkalemia And/Or Perinatal Edema,Mycobacterium Tuberculosis 1 |
4uhi_c | Q16850 | ENSG00000001630 | CYP51A1 | 100.00 | 5.80E-53 | 3.20E-57 | 393.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YMR015C | ERG5 | SGDID:S000004617 | CYP1A2 |
Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (Cholesterol 25-hydroxylase) (Cytochrome P(3)450) (Cytochrome P450 4) (Cytochrome P450-P3) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) |
1.14.14.1,4.2.1.152, | Homo sapiens | Acetaminophen Metabolism,Autoimmune Hepatitis,Major Depressive Disorder,Severe Cutaneous Adverse Reaction,Female Stress Incontinence,Maxillary Sinus Adenocarcinoma,Liver Cirrhosis,Mixed Epithelial Stromal Tumour,Cytochrome P450 Oxidoreductase Deficiency,Bilirubin Metabolic Disorder,Tardive Dyskinesia,Testicular Germ Cell Tumor,Porphyria,Hypertrophy Of Tongue Papillae,Testicular Germ Cell Cancer,Germ Cell Cancer,Breast Cancer,Colorectal Cancer,Hepatocellular Carcinoma,Clopidogrel Resistance,Angiodysplasia Of Intestine,Headache,Gastrojejunal Ulcer,Generalized Anxiety Disorder,Porphyria Cutanea Tarda,Disease Of Mental Health,Coumarin Resistance,Gastroschisis,Body Mass Index Quantitative Trait Locus 11,Danubian Endemic Familial Nephropathy,Schizophrenia,Neural Tube Defects,Antley-Bixler Syndrome,Tobacco Addiction,Hepatocellular Adenoma,Gilbert Syndrome,Autism Spectrum Disorder,Anxiety |
2hi4_a | P05177 | ENSG00000140505 | CYP1A2 | 100.00 | 2.20E-50 | 1.20E-54 | 381.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YMR015C | ERG5 | SGDID:S000004617 | cyp17a1 |
cyp17a1 |
1.14.14.19,1.14.14.32, | Danio rerio | 6b82_b | A2ATX9 | 100.00 | 3.00E-50 | 1.60E-54 | 381.90 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | |||
YMR015C | ERG5 | SGDID:S000004617 | cyp102A1 cyp102 BG04_163 |
Bifunctional cytochrome P450/NADPH--P450 reductase (Cytochrome P450(BM-3)) (Cytochrome P450BM-3) (Fatty acid monooxygenase) (Flavocytochrome P450 BM3) [Includes: Cytochrome P450 102A1 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] |
1.14.14.1,1.6.2.4, | Bacillus megaterium | 2ij2_a | P14779 | 100.00 | 2.90E-51 | 1.60E-55 | 384.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR015C | ERG5 | SGDID:S000004617 | PTGIS CYP8 CYP8A1 |
Prostacyclin synthase (EC 5.3.99.4) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) (Prostaglandin I2 synthase) |
4.2.1.152,5.3.99.4, | Homo sapiens | Dental Anomalies And Short Stature,Myocardial Infarction,Stroke, Ischemic,Acute Endometritis,Disease Of Mental Health,Pulmonary Hypertension,Lung Benign Neoplasm,Schizophrenia,Hypertension, Essential |
2iag_a | Q16647 | ENSG00000124212 | PTGIS | 100.00 | 1.20E-50 | 6.70E-55 | 382.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YMR015C | ERG5 | SGDID:S000004617 | CYP17A1 CYP17 S17AH |
Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (17-alpha-hydroxyprogesterone aldolase) (EC 1.14.14.32) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) (Steroid 17-alpha-monooxygenase) |
1.14.14.19,1.14.14.32, | Homo sapiens | Endometrial Cancer,Steroid Inherited Metabolic Disorder,Sebaceous Gland Disease,Polycystic Ovary Syndrome,Hyperandrogenism,Endometrial Hyperplasia,Disorder Of Sexual Development,Adrenal Adenoma,Bronchiectasis 3,Familial Glucocorticoid Deficiency,Hyperaldosteronism, Familial, Type I,Mycetoma,Conn'S Syndrome,Adrenal Gland Disease,Hypokalemia,Amelogenesis Imperfecta,Transvestism,Male Infertility,Smith-Lemli-Opitz Syndrome,Gender Identity Disorder,Cryptorchidism, Unilateral Or Bilateral,Leiomyoma,Cytochrome P450 Oxidoreductase Deficiency,Autoimmune Hepatitis Type 2,Leydig Cell Tumor,Endometriosis,Osteoporosis,Sertoli-Leydig Cell Tumor,Breast Cancer,Premature Menopause,Amenorrhea,Hypospadias,Transsexualism,Ovarian Disease,Hydronephrosis,46,Xy Sex Reversal,46,Xy Sex Reversal 2,Androgen Insensitivity Syndrome,Prostate Cancer,Adrenal Insufficiency, Congenital, With 46,Xy Sex Reversal, Partial Or Complete,Adrenal Cortical Carcinoma,Type 2 Diabetes Mellitus,Pseudohermaphroditism,Lynch Syndrome,Mineral Metabolism Disease,Adrenal Carcinoma,Adrenal Cortex Disease,Asperger Syndrome,Antley-Bixler Syndrome,Odontochondrodysplasia,Hypoadrenocorticism, Familial,Aromatase Excess Syndrome,Adrenal Cortical Adenoma,Hypertension, Essential,Mammographic Density,Lipoid Congenital Adrenal Hyperplasia,Adrenal Hyperplasia, Congenital, Due To 17-Alpha-Hydroxylase Deficiency,Stuttering,Premature Ovarian Failure 1,Intrahepatic Cholestasis Of Pregnancy |
5irq_c | P05093 | ENSG00000148795 | CYP17A1 | 100.00 | 2.00E-50 | 1.10E-54 | 381.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YMR015C | ERG5 | SGDID:S000004617 | CYP76AH1 |
Ferruginol synthase (EC 1.14.14.175) (Cytochrome P450 76AH1) |
1.14.14.175 | Salvia miltiorrhiza | 5ylw_a | S4UX02 | 100.00 | 2.80E-50 | 1.50E-54 | 381.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR015C | ERG5 | SGDID:S000004617 | Fatty-acid peroxygenase |
1.11.2.4 | Bacillus subtilis | 1izo_a | O31440 | 100.00 | 2.90E-55 | 1.60E-59 | 402.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YMR015C | ERG5 | SGDID:S000004617 | CYP19A1 ARO1 CYAR CYP19 |
Aromatase (EC 1.14.14.14) (CYPXIX) (Cytochrome P-450AROM) (Cytochrome P450 19A1) (Estrogen synthase) |
1.14.14.14 | Homo sapiens | Bone Disease,Bone Resorption Disease,Endometrial Cancer,Endometriosis Of Ovary,Ovarian Hyperstimulation Syndrome,Endometrial Stromal Sarcoma,Polycystic Ovary Syndrome,Hyperandrogenism,Endometrial Hyperplasia,Disorder Of Sexual Development,Diabetes Mellitus,Mycetoma,Alzheimer Disease,Amelogenesis Imperfecta, Type Ia,Osteonecrosis Of The Jaw,Teeth Hard Tissue Disease,Ovary Sarcoma,Amelogenesis Imperfecta,Prostate Disease,Hypogonadotropic Hypogonadism,Male Infertility,Smith-Lemli-Opitz Syndrome,Gender Identity Disorder,Precocious Puberty,Cryptorchidism, Unilateral Or Bilateral,Luteoma,Gynecomastia,Leiomyoma,Sporadic Breast Cancer,Actinobacillosis,Ovarian Cyst,Ovarian Endometrioid Stromal Sarcoma,Myoma,Leydig Cell Tumor,Nodular Tenosynovitis,Infertility,Endometrial Disease,Vaginal Adenoma,Testicular Germ Cell Tumor,Endometriosis,Breast Cyst,Osteoporosis,Ovarian Cancer,In Situ Carcinoma,Breast Ductal Carcinoma,Subserous Uterine Fibroid,Juvenile Nasopharyngeal Angiofibroma,Breast Carcinoma In Situ,Breast Cancer,Premature Ejaculation,Colorectal Cancer,Diffuse Peritoneal Leiomyomatosis,Hypertrophy Of Breast,Hypoactive Sexual Desire Disorder,Premature Menopause,Amenorrhea,Benign Metastasizing Leiomyoma,Transsexualism,Ovarian Disease,Estrogen Excess,Aromatase Deficiency,Mccune-Albright Syndrome,Hydronephrosis,Prostatic Hypertrophy,46,Xy Sex Reversal,Peutz-Jeghers Syndrome,46,Xy Sex Reversal 2,Precocious Puberty, Male-Limited,Breast Disease,Prostate Cancer,Disease Of Mental Health,Sertoli Cell Tumor,Choriocarcinoma,Body Mass Index Quantitative Trait Locus 11,Adrenal Cortical Carcinoma,Breast Fibroadenoma,Pseudohermaphroditism,Vaginal Discharge,Anovulation,Schizophrenia 16,Asperger Syndrome,Antley-Bixler Syndrome,Reproductive Organ Benign Neoplasm,Female Breast Cancer,Aromatase Excess Syndrome,Androgenic Alopecia,Uterine Anomalies,Mammographic Density,Pre-Malignant Neoplasm,Ductal Carcinoma In Situ,Estrogen-Receptor Positive Breast Cancer,Estrogen-Receptor Negative Breast Cancer,Progesterone-Receptor Positive Breast Cancer,Uterine Benign Neoplasm,Vaginal Benign Neoplasm,Lipoid Congenital Adrenal Hyperplasia,Stuttering,Leiomyoma, Uterine,Primary Pigmented Nodular Adrenocortical Disease,Amelogenesis Imperfecta, Type Ig,Premature Ovarian Failure 1,Adenomyosis |
3s79_a | P11511 | ENSG00000137869 | CYP19A1 | 100.00 | 8.70E-53 | 4.80E-57 | 398.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YMR015C | ERG5 | SGDID:S000004617 | cyp51 Rv0764c MTCY369.09c |
Lanosterol 14-alpha demethylase (EC 1.14.14.154) (CYPLI) (Cytochrome P450 51) (Cytochrome P450-14DM) (Cytochrome P450-LIA1) (Sterol 14-alpha demethylase) |
1.14.14.154 | Mycobacterium tuberculosis | 1e9x_a | P9WPP9 | 100.00 | 1.80E-51 | 9.70E-56 | 385.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR015C | ERG5 | SGDID:S000004617 | CYP2B |
CYP2B |
1.14.14.1 | Neotoma lepida | 5e0e_a | J9JD75 | 100.00 | 9.80E-52 | 5.40E-56 | 388.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR015C | ERG5 | SGDID:S000004617 | CYP2R1 |
Vitamin D 25-hydroxylase (EC 1.14.14.24) (Cytochrome P450 2R1) |
1.14.14.24 | Homo sapiens | Malignant Choroid Melanoma,Vitamin D-Dependent Rickets,Rickets,Hypocalcemic Vitamin D-Dependent Rickets,Vitamin D Hydroxylation-Deficient Rickets, Type 1b,Vitamin D Hydroxylation-Deficient Rickets, Type 1a |
3c6g_b | Q6VVX0 | ENSG00000186104 | CYP2R1 | 100.00 | 7.30E-51 | 4.00E-55 | 383.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YMR015C | ERG5 | SGDID:S000004617 | CYP2D6 CYP2DL1 |
Cytochrome P450 2D6 (EC 1.14.14.-) (CYPIID6) (Cholesterol 25-hydroxylase) (Cytochrome P450-DB1) (Debrisoquine 4-hydroxylase) |
1.14.14.- | Homo sapiens | Acetaminophen Metabolism,Agnosia,Heart Disease,Migraine With Or Without Aura 1,Acute Apical Periodontitis,Diabetes Mellitus,Gastroparesis,Drug-Induced Hepatitis,Hepatitis D,Autoimmune Hepatitis,Alzheimer Disease,Outlet Dysfunction Constipation,Constipation,Amelogenesis Imperfecta, Type Ib,Major Depressive Disorder,Systolic Heart Failure,Amelogenesis Imperfecta,Severe Cutaneous Adverse Reaction,Female Stress Incontinence,Multiple Chemical Sensitivity,Diabetic Neuropathy,Transvestism,Neonatal Abstinence Syndrome,Motor Neuron Disease,Toxic Oil Syndrome,Movement Disease,Substance Dependence,Delusional Disorder,Pseudobulbar Affect,Psychotic Disorder,Basal Cell Carcinoma,Adjustment Disorder,Liver Cirrhosis,Obsessive-Compulsive Disorder,Plasmodium Ovale Malaria,Drug Metabolism, Poor, Cyp2d6-Related,Plasmodium Vivax Malaria,Bilirubin Metabolic Disorder,Tardive Dyskinesia,Psychosexual Disorder,Diarrhea,Dystonia,Glucosephosphate Dehydrogenase Deficiency,Hypertrophy Of Tongue Papillae,Serotonin Syndrome,Substance Abuse,Breast Cancer,Parkinson Disease, Late-Onset,Colorectal Cancer,Human Immunodeficiency Virus Type 1,Generalized Anxiety Disorder,Neuroleptic Malignant Syndrome,Opioid Abuse,Disease Of Mental Health,Galactorrhea,Coumarin Resistance,Thiopurines, Poor Metabolism Of, 1,Mental Depression,Type 2 Diabetes Mellitus,Sulfonamide Allergy,Dementia, Lewy Body,Schizophrenia,Ophthalmomyiasis,Conidiobolomycosis,Malaria,Amelogenesis Imperfecta, Type Ie,Ichthyosis, Congenital, Autosomal Recessive 6,Pulmonary Disease, Chronic Obstructive,Attention Deficit-Hyperactivity Disorder,Gilbert Syndrome,Hypertension, Essential,Specific Developmental Disorder,Sexual Disorder,Progesterone-Receptor Positive Breast Cancer,Akinetopsia,Pain Agnosia,Anxiety,Leukodystrophy, Hypomyelinating, 13,Autism,Lung Cancer |
3tbg_d | P10635 | ENSG00000100197 | CYP2D6 | 100.00 | 1.10E-50 | 5.90E-55 | 382.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YMR015C | ERG5 | SGDID:S000004617 | CYP3A5 |
Cytochrome P450 3A5 (EC 1.14.14.1) (CYPIIIA5) (Cytochrome P450-PCN3) |
1.14.14.1 | Homo sapiens | Bronchiectasis 3,Premenstrual Tension,Multiple Chemical Sensitivity,Neutropenia,Engraftment Syndrome,Leukemia, Acute Lymphoblastic,Bilirubin Metabolic Disorder,Testicular Germ Cell Cancer,Proctitis,Clopidogrel Resistance,Prostate Cancer,Coumarin Resistance,Thiopurines, Poor Metabolism Of, 1,Gilbert Syndrome,Hypertension, Essential,Asthma |
5veu_c | P20815 | ENSG00000106258 | CYP3A5 | 100.00 | 5.10E-51 | 2.80E-55 | 384.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YMR015C | ERG5 | SGDID:S000004617 | cyp51B AFUA_7G03740 |
Sterol 14-alpha demethylase (EC 1.14.14.154) (Cytochrome P450 monooxygenase 51B) (Ergosterol biosynthesis protein cyp51B) |
1.14.14.154 | Neosartorya fumigata | 4uyl_b | E9QY26 | 100.00 | 2.90E-51 | 1.60E-55 | 385.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR015C | ERG5 | SGDID:S000004617 | cyp120 cyp slr0574 |
Putative cytochrome P450 120 (EC 1.14.-.-) |
1.14.-.- | Synechocystis sp. | 2ve3_a | Q59990 | 100.00 | 7.80E-51 | 4.30E-55 | 379.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR015C | ERG5 | SGDID:S000004617 | ERG11 CYP51 ERG16 CAALFM_C500660CA CaO19.922 |
Lanosterol 14-alpha demethylase (EC 1.14.14.154) (CYPLI) (Cytochrome P450 51) (Cytochrome P450-14DM) (Cytochrome P450-LIA1) (Sterol 14-alpha demethylase) |
1.14.14.154 | Candida albicans | 5fsa_a | P10613 | 100.00 | 2.90E-52 | 1.60E-56 | 394.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR015C | ERG5 | SGDID:S000004617 | ERG11 SCY_2394 |
ERG11 SCY_2394 |
Saccharomyces cerevisiae | 5ul0_a | A6ZSR0 | 100.00 | 1.30E-56 | 6.90E-61 | 428.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YMR015C | ERG5 | SGDID:S000004617 | CYP4B1 |
Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (Cytochrome P450 isozyme 5) |
1.14.14.1 | Oryctolagus cuniculus | 6c93_a | P15128 | 100.00 | 2.60E-51 | 1.40E-55 | 388.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR015C | ERG5 | SGDID:S000004617 | CYP1B1 |
Cytochrome P450 1B1 (EC 1.14.14.1) (CYPIB1) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) |
1.14.14.1,4.2.1.152, | Homo sapiens | Glaucoma 3, Primary Infantile, B,Endometrial Cancer,Polyp Of Corpus Uteri,Lung Cancer Susceptibility 3,Cerebral Angioma,Mycetoma,Rete Ovarii Adenoma,Amelogenesis Imperfecta,Superficial Urinary Bladder Cancer,Keratopathy,Aniridia 1,Steroid-Induced Glaucoma,Anterior Segment Dysgenesis 1,Iris Disease,Rete Ovarii Benign Neoplasm,Mixed Epithelial Stromal Tumour,Anterior Segment Dysgenesis 6,Corneal Ulcer,Phimosis,Traumatic Glaucoma,Testicular Germ Cell Tumor,Endometriosis,Testicular Germ Cell Cancer,Germ Cell Cancer,Eye Disease,Breast Cancer,Weber Syndrome,Colorectal Cancer,Excessive Tearing,Salpingitis Isthmica Nodosa,Open-Angle Glaucoma,Juvenile Glaucoma,Glaucoma 1, Open Angle, D,Acute Closed-Angle Glaucoma,Axenfeld-Rieger Syndrome, Type 3,Early-Onset Glaucoma,Primary Angle-Closure Glaucoma,Corneal Edema,Hydrophthalmos,Axenfeld-Rieger Syndrome,Microphthalmia, Isolated 2,Breast Disease,Prostate Cancer,Glaucoma 3, Primary Congenital, A,Anterior Segment Dysgenesis 5,Myopathy, Centronuclear, 5,Asperger Syndrome,Neural Tube Defects,Intraocular Pressure Quantitative Trait Locus,Sturge-Weber Syndrome,Primary Congenital Glaucoma,Glaucoma 1, Open Angle, A,Glaucoma, Primary Open Angle,Glaucoma, Normal Tension,Hepatocellular Adenoma,Megalocornea,Mammographic Density,Estrogen-Receptor Negative Breast Cancer,Keratitis, Hereditary,Amelogenesis Imperfecta, Type Ig,Medulloblastoma,Anterior Segment Dysgenesis,Intrahepatic Cholestasis Of Pregnancy,Lung Cancer,Glaucoma-Related Pigment Dispersion Syndrome,Peters-Plus Syndrome |
3pm0_a | Q16678 | ENSG00000138061 | CYP1B1 | 100.00 | 2.60E-51 | 1.40E-55 | 389.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YMR015C | ERG5 | SGDID:S000004617 | CYP11A1 CYP11A |
Cholesterol side-chain cleavage enzyme, mitochondrial (EC 1.14.15.6) (CYPXIA1) (Cholesterol desmolase) (Cytochrome P450 11A1) (Cytochrome P450(scc)) |
1.14.15.6 | Homo sapiens | Intrauterine Growth Retardation, Metaphyseal Dysplasia, Adrenal Hypoplasia Congenita, And Genital Anomalies,Steroid Inherited Metabolic Disorder,Ovarian Hyperstimulation Syndrome,Polycystic Ovary Syndrome,Hyperandrogenism,Epilepsy,Disorder Of Sexual Development,Adrenal Adenoma,Familial Glucocorticoid Deficiency,Conn'S Syndrome,Adrenal Gland Disease,Acute Adrenal Insufficiency,Amelogenesis Imperfecta,Smith-Lemli-Opitz Syndrome,Testicular Sex Cord-Stromal Neoplasm,Cryptorchidism, Unilateral Or Bilateral,Autoimmune Hepatitis Type 2,Leydig Cell Tumor,Polyendocrinopathy,Infertility,Adrenal Cortical Hypofunction,Inherited Isolated Adrenal Insufficiency Due To Partial Cyp11a1 Deficiency,Juvenile Nasopharyngeal Angiofibroma,Premature Menopause,Autoimmune Polyendocrine Syndrome,Hypospadias,Ovarian Disease,46,Xy Sex Reversal,46,Xy Sex Reversal 2,Choriocarcinoma,Body Mass Index Quantitative Trait Locus 11,Adrenal Insufficiency, Congenital, With 46,Xy Sex Reversal, Partial Or Complete,Adrenal Cortical Carcinoma,Pseudohermaphroditism,Adrenal Carcinoma,Adrenal Cortex Disease,Asperger Syndrome,Antley-Bixler Syndrome,Hypoadrenocorticism, Familial,Adrenal Cortical Adenoma,Lipoid Congenital Adrenal Hyperplasia,Amelogenesis Imperfecta, Type Ig |
3n9y_b | P05108 | ENSG00000140459 | CYP11A1 | 100.00 | 7.40E-53 | 4.00E-57 | 397.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YMR015C | ERG5 | SGDID:S000004617 | MaF1660_ph0012 |
MaF1660_ph0012 |
Mycobacterium phage | 6n6q_b | V5UQK0 | 100.00 | 3.00E-52 | 1.60E-56 | 392.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YMR015C | ERG5 | SGDID:S000004617 | NF0102700 |
NF0102700 |
Naegleria fowleri | 5tl8_a | A0A2H4A2U9 | 100.00 | 6.10E-53 | 3.30E-57 | 396.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YMR015C | ERG5 | SGDID:S000004617 | CYP2C9 CYP2C10 |
Cytochrome P450 2C9 (EC 1.14.14.1) ((R)-limonene 6-monooxygenase) (EC 1.14.14.53) ((S)-limonene 6-monooxygenase) (EC 1.14.14.51) ((S)-limonene 7-monooxygenase) (EC 1.14.14.52) (CYPIIC9) (Cholesterol 25-hydroxylase) (Cytochrome P-450MP) (Cytochrome P450 MP-4) (Cytochrome P450 MP-8) (Cytochrome P450 PB-1) (S-mephenytoin 4-hydroxylase) |
1.14.14.1,1.14.14.51,1.14.14.52,1.14.14.53, | Homo sapiens | Heart Disease,Vascular Disease,Portal Vein Thrombosis,Diabetes Mellitus,Drug-Induced Hepatitis,Hepatitis D,Alzheimer Disease,Myocardial Infarction,Major Depressive Disorder,Severe Cutaneous Adverse Reaction,Multiple Chemical Sensitivity,Chronic Kidney Disease,Bilirubin Metabolic Disorder,Esophageal Candidiasis,Koro,Heart Conduction Disease,Hypertrophy Of Tongue Papillae,Diaphragm Disease,Diffuse Alveolar Hemorrhage,Colorectal Cancer,Gingival Overgrowth,Clopidogrel Resistance,Angiodysplasia Of Intestine,Pulmonary Artery Disease,Gastrojejunal Ulcer,Tracheal Calcification,Small Intestine Diverticulitis,Disease Of Mental Health,Phenytoin Toxicity,Coumarin Resistance,Type 2 Diabetes Mellitus,Abacavir Allergy,Phenytoin Allergy,Sulfonamide Allergy,Sulfamethoxazole Allergy,Trimethoprim Allergy,Halothane Hepatitis,Colorectal Adenoma,Gilbert Syndrome,Colon Adenoma,Hypertension, Essential,Marfan Syndrome,Asthma,Budd-Chiari Syndrome |
5a5i_a | P11712 | ENSG00000138109 | CYP2C9 | 100.00 | 9.40E-52 | 5.10E-56 | 389.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YMR015C | ERG5 | SGDID:S000004617 | Cyp24a1 Cyp24 |
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (24-OHase) (Vitamin D(3) 24-hydroxylase) (EC 1.14.15.16) (Cytochrome P450 24A1) (Cytochrome P450-CC24) |
1.14.15.16 | Rattus norvegicus | 3k9v_a | Q09128 | 100.00 | 1.90E-50 | 1.10E-54 | 381.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR015C | ERG5 | SGDID:S000004617 | CYP90B1 DWF4 At3g50660 T3A5.40 |
Cytochrome P450 90B1 (EC 1.14.-.-) (Protein DWARF 4) (Dwarf4) (Steroid 22-alpha-hydroxylase) |
1.14.-.- | Arabidopsis thaliana | 6a15_a | O64989 | 100.00 | 1.20E-51 | 6.50E-56 | 386.50 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | |||
YMR015C | ERG5 | SGDID:S000004617 | SCO5223 |
Epi-isozizaene 5-monooxygenase/(E)-beta-farnesene synthase (EC 1.14.13.106) (EC 4.2.3.47) (Cytochrome P450 170A1) (CYP170A1) |
1.14.13.106,4.2.3.47, | Streptomyces coelicolor | 3dbg_a | Q9K498 | 100.00 | 2.80E-51 | 1.50E-55 | 385.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR015C | ERG5 | SGDID:S000004617 | CYP2A6 CYP2A3 |
Cytochrome P450 2A6 (EC 1.14.13.-) (1,4-cineole 2-exo-monooxygenase) (CYPIIA6) (Coumarin 7-hydroxylase) (Cytochrome P450 IIA3) (Cytochrome P450(I)) |
1.14.13.- | Homo sapiens | Acetaminophen Metabolism,Tinea Cruris,Crigler-Najjar Syndrome, Type I,Substance Dependence,Liver Cirrhosis,Bilirubin Metabolic Disorder,Letrozole Toxicity,Alcoholic Liver Cirrhosis,Disease Of Mental Health,Coumarin Resistance,Body Mass Index Quantitative Trait Locus 11,Halothane Hepatitis,Diamond-Blackfan Anemia 2,Tobacco Addiction,Lung Cancer |
1z11_a | P11509 | ENSG00000255974 | CYP2A6 | 100.00 | 9.90E-52 | 5.40E-56 | 389.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YMR015C | ERG5 | SGDID:S000004617 | CYP7A1 CYP7 |
Cytochrome P450 7A1 (24-hydroxycholesterol 7-alpha-hydroxylase) (EC 1.14.14.26) (CYPVII) (Cholesterol 7-alpha-hydroxylase) (Cholesterol 7-alpha-monooxygenase) (EC 1.14.14.23) |
1.14.14.23,1.14.14.26, | Homo sapiens | Functional Diarrhea,Bile Duct Disease,Lipid Storage Disease,Outlet Dysfunction Constipation,Hypercholesterolemia Due To Cholesterol 7alpha-Hydroxylase Deficiency,Primary Biliary Cholangitis,Biliary Tract Disease,Sitosterolemia,Hyperthyroidism,Leber Plus Disease,Bilirubin Metabolic Disorder,Cholestasis, Progressive Familial Intrahepatic, 2,Cholelithiasis,Xanthomatosis,Cholestasis,Extrahepatic Cholestasis,Cholestasis, Progressive Familial Intrahepatic, 3,Familial Hypercholesterolemia,Lipid Metabolism Disorder,Hypothyroidism,Cholangitis, Primary Sclerosing,Bile Acid Synthesis Defect, Congenital, 2,Asperger Syndrome,Cholestasis, Benign Recurrent Intrahepatic, 2,Cholestasis, Benign Recurrent Intrahepatic, 1,Gallbladder Disease,Heart Defects, Congenital, And Other Congenital Anomalies,Progressive Familial Intrahepatic Cholestasis,Cholestasis, Progressive Familial Intrahepatic, 1,Cerebrotendinous Xanthomatosis |
3v8d_a | P22680 | ENSG00000167910 | CYP7A1 | 100.00 | 6.80E-51 | 3.70E-55 | 384.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YMR015C | ERG5 | SGDID:S000004617 | ptgis ptgisl |
Prostacyclin synthase (EC 5.3.99.4) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) (Prostaglandin I2 synthase) (PGIS) |
4.2.1.152,5.3.99.4, | Danio rerio | 3b98_a | F1RE08 | 100.00 | 1.40E-52 | 7.90E-57 | 394.40 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | |||
YMR015C | ERG5 | SGDID:S000004617 | cyp51 MCA2711 |
cyp51 MCA2711 |
1.14.13.70 | Methylococcus capsulatus | 6mcw_a | Q603T8 | 100.00 | 1.70E-52 | 9.40E-57 | 401.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR015C | ERG5 | SGDID:S000004617 | ERG11 CYP51 YHR007C |
Lanosterol 14-alpha demethylase (EC 1.14.14.154) (CYPLI) (Cytochrome P450 51) (Cytochrome P450-14DM) (Cytochrome P450-LIA1) (Sterol 14-alpha demethylase) |
1.14.14.154 | Saccharomyces cerevisiae | 4lxj_a | P10614 | 100.00 | 2.40E-55 | 1.30E-59 | 420.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |