Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
YMR208W | ERG12 | SGDID:S000004821 | mvaK1 SP_0381 |
mvaK1 SP_0381 |
Streptococcus pneumoniae | 2oi2_a | A0A0H2UNK6 | 99.90 | 4.90E-28 | 3.20E-32 | 218.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YMR208W | ERG12 | SGDID:S000004821 | hddA Cj1425c |
hddA Cj1425c |
Campylobacter jejuni | 4n3o_a | Q0P8I9 | 99.90 | 3.60E-29 | 2.40E-33 | 230.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YMR208W | ERG12 | SGDID:S000004821 | SSO2989 |
Diphosphomevalonate decarboxylase (DMD) (EC 4.1.1.33) |
4.1.1.33 | Saccharolobus solfataricus | 4z7y_e | Q97UL5 | 99.20 | 4.50E-15 | 2.90E-19 | 134.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | Mvk |
Mevalonate kinase (MK) (EC 2.7.1.36) |
2.7.1.36 | Rattus norvegicus | 1kvk_a | P17256 | 99.90 | 1.50E-31 | 9.90E-36 | 251.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | fkp |
fkp |
Bacteroides fragilis | 5yys_c | Q58T34 | 99.80 | 1.60E-26 | 1.00E-30 | 237.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YMR208W | ERG12 | SGDID:S000004821 | GALK2 GK2 |
N-acetylgalactosamine kinase (EC 2.7.1.157) (GalNAc kinase) (Galactokinase 2) |
2.7.1.157 | Homo sapiens | Galactosemia Ii,Galactosemia Iii,Galactosemia I |
2a2c_a | Q01415 | ENSG00000156958 | GALK2 | 99.90 | 2.90E-30 | 1.90E-34 | 246.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YMR208W | ERG12 | SGDID:S000004821 | thrB lmo2545 |
Homoserine kinase (HK) (HSK) (EC 2.7.1.39) |
2.7.1.39 | Listeria monocytogenes | 3hul_a | Q8Y4A6 | 99.70 | 1.70E-22 | 1.10E-26 | 182.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | thrB Cgl1184 cg1338 |
Homoserine kinase (HK) (HSK) (EC 2.7.1.39) |
2.7.1.39 | Corynebacterium glutamicum | 5wat_a | P07128 | 99.60 | 3.80E-20 | 2.50E-24 | 167.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | mvk MJ1087 |
Mevalonate kinase (MK) (MVK) (EC 2.7.1.36) |
2.7.1.36 | Methanocaldococcus jannaschii | 1kkh_a | Q58487 | 99.90 | 1.50E-28 | 9.70E-33 | 224.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | Ta1305 |
Mevalonate 3-kinase (M3K) (EC 2.7.1.185) (ATP:(R)-mevalonate 3-phosphotransferase) (ATP:(R)-MVA 3 phosphotransferase) |
2.7.1.185 | Thermoplasma acidophilum | 4rkp_b | Q9HIN1 | 99.30 | 9.60E-17 | 6.30E-21 | 146.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | ispE TTHA0170 |
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (CMK) (EC 2.7.1.148) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase) |
2.7.1.148 | Thermus thermophilus | 1uek_a | P83700 | 99.40 | 1.70E-17 | 1.10E-21 | 146.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | ispE c1666 |
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (CMK) (EC 2.7.1.148) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase) |
2.7.1.148 | Escherichia coli | 1oj4_a | Q8FI04 | 99.50 | 1.90E-18 | 1.30E-22 | 153.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
YMR208W | ERG12 | SGDID:S000004821 | galK PH0369 |
Galactokinase (EC 2.7.1.6) (Galactose kinase) |
2.7.1.6 | Pyrococcus horikoshii | 2dei_a | O58107 | 99.90 | 5.80E-29 | 3.80E-33 | 230.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | Tb10.05.0010 |
Tb10.05.0010 |
4.1.1.33 | Trypanosoma brucei | 2hke_a | Q388P2 | 99.50 | 3.60E-18 | 2.30E-22 | 158.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | mvaD D9V05_03125 E1M98_07305 E1N00_04745 E1N04_06965 E1N09_04790 E1N10_07915 E1N11_07670 E1N12_04725 FHQ17_11140 |
mvaD D9V05_03125 E1M98_07305 E1N00_04745 E1N04_06965 E1N09_04790 E1N10_07915 E1N11_07670 E1N12_04725 FHQ17_11140 |
4.1.1.33 | Staphylococcus epidermidis | 3qt5_a | Q9FD73 | 99.70 | 3.00E-21 | 2.00E-25 | 176.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | MVD MPD |
Diphosphomevalonate decarboxylase (EC 4.1.1.33) (Mevalonate (diphospho)decarboxylase) (MDDase) (Mevalonate pyrophosphate decarboxylase) |
4.1.1.33 | Homo sapiens | Punctate Porokeratosis,Linear Porokeratosis,Porokeratosis,Scirrhous Adenocarcinoma,Porokeratosis 7, Multiple Types,3-Methylglutaconic Aciduria,Pelizaeus-Merzbacher Disease |
3d4j_a | P53602 | ENSG00000167508 | MVD | 99.20 | 4.70E-15 | 3.10E-19 | 137.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YMR208W | ERG12 | SGDID:S000004821 | BT_0474 |
BT_0474 |
Bacteroides thetaiotaomicron | 3k85_b | Q8AAJ0 | 99.90 | 4.00E-30 | 2.60E-34 | 238.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YMR208W | ERG12 | SGDID:S000004821 | thrB MAB_1437 |
Homoserine kinase (HK) (HSK) (EC 2.7.1.39) |
2.7.1.39 | Mycobacteroides abscessus | 6cyz_a | B1MLU6 | 99.50 | 1.60E-18 | 1.10E-22 | 156.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | thrB CHU_0074 |
thrB CHU_0074 |
Cytophaga hutchinsonii | 4p52_a | Q11YZ8 | 99.70 | 2.60E-22 | 1.70E-26 | 183.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YMR208W | ERG12 | SGDID:S000004821 | Mvd |
Diphosphomevalonate decarboxylase (EC 4.1.1.33) (Mevalonate (diphospho)decarboxylase) (MDDase) (Mevalonate pyrophosphate decarboxylase) |
4.1.1.33 | Mus musculus | 3f0n_b | Q99JF5 | 99.50 | 5.00E-18 | 3.20E-22 | 158.90 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | MVD1 ERG19 MPD YNR043W N3427 |
Diphosphomevalonate decarboxylase (EC 4.1.1.33) (Ergosterol biosynthesis protein 19) (Mevalonate pyrophosphate decarboxylase) (Mevalonate-5-diphosphate decarboxylase) (MDD) (MDDase) |
4.1.1.33 | Saccharomyces cerevisiae | 1fi4_a | P32377 | 98.90 | 3.20E-13 | 2.10E-17 | 125.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | lpg2040 |
lpg2040 |
4.1.1.33 | Legionella pneumophila | 3lto_a | Q5ZTW8 | 99.30 | 1.70E-16 | 1.10E-20 | 143.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | MVK |
Mevalonate kinase (MK) (EC 2.7.1.36) |
2.7.1.36 | Homo sapiens | Zellweger Syndrome,Peroxisomal Disease,Retinitis Pigmentosa,Myopathy,Schnitzler Syndrome,Cervical Adenitis,Familial Cold Autoinflammatory Syndrome,Pharyngitis,Punctate Porokeratosis,Rhizomelic Chondrodysplasia Punctata,Behcet Syndrome,Relapsing Fever,Fundus Dystrophy,Diarrhea,Pyoderma Gangrenosum,Linear Porokeratosis,Adenosylcobalamin Deficiency,Pityriasis Rubra Pilaris,Porokeratosis 1, Multiple Types,Porokeratosis 3, Multiple Types,Methylmalonic Acidemia,Erysipelas,Galactosemia I,Mevalonic Aciduria,Porokeratosis,Pyogenic Sterile Arthritis, Pyoderma Gangrenosum, And Acne,Nemaline Myopathy 5,Exanthem,Sideroblastic Anemia With B-Cell Immunodeficiency, Periodic Fevers, And Developmental Delay,Familial Cold Autoinflammatory Syndrome 2,Blau Syndrome,Autosomal Recessive Disease,Muckle-Wells Syndrome,Periodic Fever, Familial, Autosomal Dominant,Cinca Syndrome,Familial Mediterranean Fever,Methylmalonic Aciduria, Cblb Type,Pelizaeus-Merzbacher Disease,Proteasome-Associated Autoinflammatory Syndrome 1,Hyper-Igd Syndrome,Phenylketonuria |
2r3v_c | Q03426 | ENSG00000110921 | MVK | 99.90 | 1.40E-33 | 9.10E-38 | 265.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YMR208W | ERG12 | SGDID:S000004821 | lin0012 |
lin0012 |
2.7.4.2 | Listeria innocua | 3k17_d | Q92FU1 | 99.90 | 5.60E-29 | 3.70E-33 | 231.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | GAL3 YDR009W YD8119.14 |
Protein GAL3 |
Saccharomyces cerevisiae | 3v2u_c | P13045 | 99.80 | 3.60E-26 | 2.30E-30 | 220.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YMR208W | ERG12 | SGDID:S000004821 | thrB MJ1104 |
Homoserine kinase (HK) (HSK) (EC 2.7.1.39) |
2.7.1.39 | Methanocaldococcus jannaschii | 1fwl_c | Q58504 | 99.70 | 4.90E-23 | 3.20E-27 | 185.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | galK LL1983 L0028 |
Galactokinase (EC 2.7.1.6) (Galactose kinase) |
2.7.1.6 | Lactococcus lactis | 1pie_a | Q9R7D7 | 99.90 | 9.10E-30 | 6.00E-34 | 240.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | ispE Rv1011 MTCI237.28 |
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (CMK) (EC 2.7.1.148) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase) |
2.7.1.148 | Mycobacterium tuberculosis | 3pye_a | P9WKG7 | 99.80 | 2.90E-23 | 1.90E-27 | 188.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | mvk MM_1762 |
mvk MM_1762 |
2.7.1.36 | Methanosarcina mazei | 4hac_b | Q8PW39 | 99.90 | 4.20E-29 | 2.70E-33 | 228.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | ispE aq_915 |
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (CMK) (EC 2.7.1.148) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase) |
2.7.1.148 | Aquifex aeolicus | 2v34_b | O67060 | 99.50 | 3.70E-18 | 2.40E-22 | 151.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | LMJF_31_0560 |
LMJF_31_0560 |
2.7.1.36 | Leishmania major | 2hfs_b | Q4Q6K7 | 99.90 | 3.80E-30 | 2.50E-34 | 236.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | mvaD G6X35_00705 G6Y24_14745 G6Y28_09035 G6Y30_01400 GO706_12855 HK402_03170 NCTC7878_01231 SAST44_00622 |
mvaD G6X35_00705 G6Y24_14745 G6Y28_09035 G6Y30_01400 GO706_12855 HK402_03170 NCTC7878_01231 SAST44_00622 |
4.1.1.33 | Staphylococcus aureus | 2hk2_b | Q9FD84 | 99.70 | 1.50E-22 | 9.70E-27 | 185.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | ispE ipk ychB b1208 JW1199 |
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (CMK) (EC 2.7.1.148) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase) |
2.7.1.148 | Escherichia coli | 2ww4_b | P62615 | 99.50 | 1.90E-18 | 1.30E-22 | 153.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
YMR208W | ERG12 | SGDID:S000004821 | mvaK2 spr0340 |
mvaK2 spr0340 |
Streptococcus pneumoniae | 3gon_a | Q8DR49 | 99.80 | 1.00E-25 | 6.60E-30 | 207.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YMR208W | ERG12 | SGDID:S000004821 | wcbL BPSL2796 |
wcbL BPSL2796 |
Burkholderia pseudomallei | 4usk_b | H7C745 | 99.90 | 3.90E-31 | 2.50E-35 | 244.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YMR208W | ERG12 | SGDID:S000004821 | thrB YPN_0332 YP516_0338 |
Homoserine kinase (HK) (HSK) (EC 2.7.1.39) |
2.7.1.39 | Yersinia pestis | 4rpf_b | Q1CMW6 | 99.70 | 1.10E-22 | 7.10E-27 | 184.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | mvaD SPy_0877 |
mvaD SPy_0877 |
4.1.1.33 | Streptococcus pyogenes | 2gs8_a | Q9A097 | 99.70 | 1.10E-21 | 7.10E-26 | 178.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YMR208W | ERG12 | SGDID:S000004821 | GALK1 GALK |
Galactokinase (EC 2.7.1.6) (Galactose kinase) |
2.7.1.6 | Homo sapiens | Retinitis Pigmentosa,Senile Cataract,Epidermolysis Bullosa Simplex,Cataract,Epidermolysis Bullosa With Pyloric Atresia,Epidermolysis Bullosa,Carbohydrate Metabolic Disorder,Noonan Syndrome 8,Premature Menopause,Junctional Epidermolysis Bullosa,Epidermolysis Bullosa, Junctional, Non-Herlitz Type,Epidermolysis Bullosa Junctionalis With Pyloric Atresia,Lens Disease,Retinitis Pigmentosa 24,Galactosemia Ii,Galactosemia Iii,Galactosemia I,Mevalonic Aciduria,Retinitis Pigmentosa 23,Aniseikonia,Epidermolysis Bullosa Simplex, Localized,Deafness, Autosomal Dominant 69,Lowe Oculocerebrorenal Syndrome,Pyloric Atresia |
6q3w_b | P51570 | ENSG00000108479 | GALK1 | 99.90 | 1.30E-28 | 8.30E-33 | 231.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YMR208W | ERG12 | SGDID:S000004821 | mvaD EF_0903 |
mvaD EF_0903 |
4.1.1.33 | Enterococcus faecalis | 5v2l_a | Q837E0 | 99.80 | 1.60E-24 | 1.00E-28 | 199.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |