| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YNL045W | LAP2 | SGDID:S000004990 | ERAP1 APPILS ARTS1 KIAA0525 UNQ584/PRO1154 |
Endoplasmic reticulum aminopeptidase 1 (EC 3.4.11.-) (ARTS-1) (Adipocyte-derived leucine aminopeptidase) (A-LAP) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP) (Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator) |
3.4.11.- | Homo sapiens | Cheilitis,Spondylitis,Enthesopathy,Panuveitis,Spondyloarthropathy 1,Behcet Syndrome,Iritis,Uveal Disease,Juvenile Ankylosing Spondylitis,Birdshot Chorioretinopathy,Inflammatory Bowel Disease,Peeling Skin With Leukonychia, Acral Punctate Keratoses, Cheilitis, And Knuckle Pads,Hypertension, Essential,Autoimmune Disease Of Skin And Connective Tissue,Autoimmune Disease Of Cardiovascular System,Psoriatic Arthritis,Knuckle Pads,Spinal Disease |
6q4r_a | Q9NZ08 | ENSG00000164307 | ERAP1 | 100.00 | 4.40E-44 | 3.10E-48 | 416.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YNL045W | LAP2 | SGDID:S000004990 | ENPEP |
Glutamyl aminopeptidase (EAP) (EC 3.4.11.7) (Aminopeptidase A) (AP-A) (Differentiation antigen gp160) (CD antigen CD249) |
3.4.11.7 | Homo sapiens | Gestational Choriocarcinoma,Syphilitic Meningitis,Long Qt Syndrome,Pre-Eclampsia,Vas Deferens, Congenital Bilateral Aplasia Of,Choriocarcinoma,Atrial Septal Defect 4,Atrial Septal Defect 3,Renal Cell Carcinoma, Nonpapillary,Hypertension, Essential |
4kxd_a | Q07075 | ENSG00000138792 | ENPEP | 100.00 | 2.70E-43 | 1.80E-47 | 408.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YNL045W | LAP2 | SGDID:S000004990 | CPS_3470 |
CPS_3470 |
3.4.11.2 | Colwellia psychrerythraea | 3cia_a | Q7WVY1 | 100.00 | 1.10E-81 | 7.60E-86 | 698.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL045W | LAP2 | SGDID:S000004990 | LTA4H LTA4 |
Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase) (Tripeptide aminopeptidase LTA4H) (EC 3.4.11.4) |
3.3.2.6 | Homo sapiens | Psoriasis,Meningitis,Myocardial Infarction,Lymph Node Tuberculosis,Arthrogryposis, Distal, Type 1a,Intestinal Tuberculosis,Orbital Granuloma,Tuberculous Meningitis,Leprosy 3,Asthma |
1sqm_a | P09960 | ENSG00000111144 | LTA4H | 100.00 | 1.30E-80 | 8.90E-85 | 691.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YNL045W | LAP2 | SGDID:S000004990 | TAF2 CIF150 TAF2B |
Transcription initiation factor TFIID subunit 2 (150 kDa cofactor of initiator function) (RNA polymerase II TBP-associated factor subunit B) (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150) |
Homo sapiens | Microcephaly,Mental Retardation, Autosomal Recessive 40 |
5fur_i | Q6P1X5 | 100.00 | 1.80E-42 | 1.20E-46 | 410.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL045W | LAP2 | SGDID:S000004990 | AMP1 |
M1 family aminopeptidase (EC 3.4.11.-) (Pfa-M1) |
3.4.11.- | Plasmodium falciparum | 3ebh_a | O96935 | 100.00 | 2.00E-42 | 1.40E-46 | 400.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL045W | LAP2 | SGDID:S000004990 | pepN lpg1497 |
pepN lpg1497 |
3.4.11.2 | Legionella pneumophila | 5zi7_b | Q5ZVE3 | 100.00 | 1.60E-44 | 1.10E-48 | 414.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL045W | LAP2 | SGDID:S000004990 | LNPEP OTASE |
Leucyl-cystinyl aminopeptidase (Cystinyl aminopeptidase) (EC 3.4.11.3) (Insulin-regulated membrane aminopeptidase) (Insulin-responsive aminopeptidase) (IRAP) (Oxytocinase) (OTase) (Placental leucine aminopeptidase) (P-LAP) [Cleaved into: Leucyl-cystinyl aminopeptidase, pregnancy serum form] |
3.4.11.3 | Homo sapiens | Pineoblastoma,Trophoblastic Neoplasm,Gestational Diabetes Insipidus,Dysgerminoma Of Ovary,Pre-Eclampsia,Arthrogryposis, Renal Dysfunction, And Cholestasis 2,Androgen Insensitivity Syndrome,Choriocarcinoma,Placental Site Trophoblastic Tumor,Diabetes Insipidus, Neurohypophyseal,Diabetes Insipidus, Nephrogenic, Autosomal,Type 2 Diabetes Mellitus,Birdshot Chorioretinopathy,Hypertension, Essential,Arthrogryposis, Renal Dysfunction, And Cholestasis 1 |
5mj6_a | Q9UIQ6 | ENSG00000113441 | LNPEP | 100.00 | 1.80E-43 | 1.30E-47 | 409.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YNL045W | LAP2 | SGDID:S000004990 | LAP2 YNL045W N2535 |
Leucine aminopeptidase 2 (EC 3.4.11.-) (Epoxide hydrolase) (EC 3.3.2.10) (Leucyl aminopeptidase yscIV) (AP IV) (Leukotriene A-4 hydrolase homolog) (LTA-4 hydrolase) |
3.3.2.10 | Saccharomyces cerevisiae | 2xpy_a | Q10740 | 100.00 | 7.30E-89 | 5.00E-93 | 758.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL045W | LAP2 | SGDID:S000004990 | pepN NMB1416 |
pepN NMB1416 |
3.4.11.2 | Neisseria meningitidis | 4qhp_a | Q9JYV4 | 100.00 | 6.90E-42 | 4.80E-46 | 395.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL045W | LAP2 | SGDID:S000004990 | ANPEP APN CD13 PEPN |
Aminopeptidase N (AP-N) (hAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (Myeloid plasma membrane glycoprotein CD13) (gp150) (CD antigen CD13) |
3.4.11.2 | Homo sapiens | Breast Rhabdomyosarcoma,Vascular Cancer,Childhood Acute Lymphocytic Leukemia,B-Lymphoblastic Leukemia/Lymphoma,Hydrops Of Gallbladder,Myeloproliferative Neoplasm,Gastroenteritis,Colon Adenocarcinoma,Pancytopenia,Mixed Phenotype Acute Leukemia,Myelophthisic Anemia,Acute Leukemia,Leukemia, Acute Myeloid,Leukemia, Acute Lymphoblastic,Autoimmune Disease,Central Nervous System Leukemia,Reticulosarcoma,Tetrasomy 21,Tonsillitis,Myeloid Sarcoma,Acute Megakaryocytic Leukemia,Lactose Intolerance,Aleukemic Leukemia Cutis,Deficiency Anemia,Respiratory Failure,Mast-Cell Sarcoma,Disease By Infectious Agent,Myelodysplastic Syndrome,Acute Promyelocytic Leukemia,Renal Cell Carcinoma, Nonpapillary,Abetalipoproteinemia,Lymphoma,B-Cell Adult Acute Lymphocytic Leukemia,Lung Cancer |
4fyt_a | P15144 | ENSG00000166825 | ANPEP | 100.00 | 1.70E-44 | 1.20E-48 | 419.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YNL045W | LAP2 | SGDID:S000004990 | 1278415 AgaP_AGAP004809 |
1278415 AgaP_AGAP004809 |
Anopheles gambiae | 4wz9_b | Q7Q2T8 | 100.00 | 2.70E-43 | 1.80E-47 | 409.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YNL045W | LAP2 | SGDID:S000004990 | pepN b0932 JW0915 |
Aminopeptidase N (EC 3.4.11.2) (Alpha-aminoacylpeptide hydrolase) |
3.4.11.2 | Escherichia coli | 3b34_a | P04825 | 100.00 | 6.10E-44 | 4.10E-48 | 408.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
| YNL045W | LAP2 | SGDID:S000004990 | ERAP2 LRAP |
Endoplasmic reticulum aminopeptidase 2 (EC 3.4.11.-) (Leukocyte-derived arginine aminopeptidase) (L-RAP) |
3.4.11.- | Homo sapiens | Spondylitis,Panuveitis,Immunodeficiency 48,Spondyloarthropathy 1,Behcet Syndrome,Pre-Eclampsia,Eclampsia,Papillary Thyroid Microcarcinoma,Birdshot Chorioretinopathy |
5ab0_a | Q6P179 | ENSG00000164308 | ERAP2 | 100.00 | 3.80E-44 | 2.60E-48 | 417.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YNL045W | LAP2 | SGDID:S000004990 | trf3 Ta0815 |
Tricorn protease-interacting factor F3 (EC 3.4.11.-) |
3.4.11.- | Thermoplasma acidophilum | 1z5h_a | O93655 | 100.00 | 9.90E-45 | 6.80E-49 | 414.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YNL045W | LAP2 | SGDID:S000004990 | pepN FTT_1793c |
pepN FTT_1793c |
3.4.11.2 | Francisella tularensis | 5dll_a | Q5NE65 | 100.00 | 1.20E-43 | 7.90E-48 | 408.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |