Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
YNL238W | KEX2 | SGDID:S000005182 | THET |
Thermitase (EC 3.4.21.66) |
3.4.21.66 | Thermoactinomyces vulgaris | 1tec_e | P04072 | 99.80 | 1.30E-24 | 1.20E-28 | 227.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL238W | KEX2 | SGDID:S000005182 | patG |
patG |
Prochloron didemni | 4akt_a | Q52QJ1 | 99.80 | 8.80E-25 | 7.70E-29 | 238.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL238W | KEX2 | SGDID:S000005182 | epiP SACOL1874 |
epiP SACOL1874 |
Staphylococcus aureus | 3qfh_h | A0A0H2WX20 | 99.90 | 3.30E-27 | 2.90E-31 | 264.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL238W | KEX2 | SGDID:S000005182 | MSMEG_0624 |
MSMEG_0624 |
Mycolicibacterium smegmatis | 4kg7_a | A0QQ47 | 99.90 | 2.10E-27 | 1.90E-31 | 259.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL238W | KEX2 | SGDID:S000005182 | SUBS |
Subtilisin Savinase (EC 3.4.21.62) (Alkaline protease) |
3.4.21.62 | Bacillus lentus | 5ard_a | P29600 | 99.80 | 1.40E-24 | 1.30E-28 | 225.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL238W | KEX2 | SGDID:S000005182 | kscp |
kscp |
Bacillus | 1gt9_2 | Q8RR56 | 99.70 | 4.50E-22 | 4.00E-26 | 216.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL238W | KEX2 | SGDID:S000005182 | subC apr |
Subtilisin Carlsberg (EC 3.4.21.62) |
3.4.21.62 | Bacillus licheniformis | 1be8_a | P00780 | 99.80 | 3.50E-25 | 3.20E-29 | 231.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL238W | KEX2 | SGDID:S000005182 | scpC |
scpC |
3.4.21.110 | Streptococcus pyogenes | 5xya_a | Q3HV58 | 99.80 | 2.20E-26 | 1.90E-30 | 294.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL238W | KEX2 | SGDID:S000005182 | KEX2 QDS1 YNL238W N1122 |
Kexin (EC 3.4.21.61) (Protease KEX2) (Proteinase YSCF) |
3.4.21.61 | Saccharomyces cerevisiae | 1r64_b | P13134 | 100.00 | 5.90E-51 | 5.20E-55 | 464.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL238W | KEX2 | SGDID:S000005182 | Subtilisin-like protease 1 (EC 3.4.21.62) (PfSUB-1) |
Plasmodium falciparum | 4lvn_a | Q868D6 | 99.90 | 4.00E-27 | 3.60E-31 | 254.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||||
YNL238W | KEX2 | SGDID:S000005182 | BBI15_13285 |
BBI15_13285 |
Planococcus plakortidis | 6f9m_b | A0A3B6UEW8 | 99.80 | 2.40E-24 | 2.10E-28 | 231.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL238W | KEX2 | SGDID:S000005182 | KEK_05522 |
KEK_05522 |
Mycolicibacterium thermoresistibile | 4hvl_a | G7CDQ2 | 99.90 | 7.20E-27 | 6.30E-31 | 256.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL238W | KEX2 | SGDID:S000005182 | CUCM1 |
Cucumisin (EC 3.4.21.25) (allergen Cuc m 1) |
3.4.21.25 | Cucumis melo | 4yn3_a | Q39547 | 99.80 | 5.10E-26 | 4.40E-30 | 266.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL238W | KEX2 | SGDID:S000005182 | pstI |
Aqualysin-1 (EC 3.4.21.111) (Aqualysin-I) |
3.4.21.111 | Thermus aquaticus | 4dzt_a | P08594 | 99.80 | 2.20E-23 | 2.00E-27 | 217.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL238W | KEX2 | SGDID:S000005182 | apa1 |
apa1 |
Pseudoalteromonas | 1wvm_b | Q65Z69 | 99.80 | 7.30E-26 | 6.30E-30 | 254.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL238W | KEX2 | SGDID:S000005182 | Keratinase |
Keratinase |
Meiothermus taiwanensis | 5wsl_b | A0A2H4A2Y5 | 99.80 | 1.30E-23 | 1.10E-27 | 223.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL238W | KEX2 | SGDID:S000005182 | sub1 PVC01_100035100 PVT01_100029100 |
sub1 PVC01_100035100 PVT01_100029100 |
3.4.21.62 | Plasmodium vivax | 4tr2_a | E6Y8B9 | 99.90 | 1.50E-28 | 1.20E-32 | 289.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL238W | KEX2 | SGDID:S000005182 | Serine protease (Fragment) |
Serine protease (Fragment) |
Purpureocillium lilacinum | 3f7o_a | Q01471 | 99.70 | 6.70E-23 | 5.90E-27 | 215.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL238W | KEX2 | SGDID:S000005182 | Putative 36kDa protease |
Putative 36kDa protease |
Lysinibacillus sphaericus | 1ea7_a | Q9S3L6 | 99.80 | 2.50E-23 | 2.20E-27 | 220.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL238W | KEX2 | SGDID:S000005182 | aprE apr aprA sprE BSU10300 |
Subtilisin E (EC 3.4.21.62) |
3.4.21.62 | Bacillus subtilis | 3whi_b | P04189 | 99.90 | 2.50E-27 | 2.20E-31 | 258.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL238W | KEX2 | SGDID:S000005182 | TK1689 |
Subtilisin-like serine protease (EC 3.4.21.62) (Tk-SP) |
3.4.21.62 | Thermococcus kodakarensis | 3afg_a | Q5JIZ5 | 99.90 | 5.90E-33 | 5.00E-37 | 320.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL238W | KEX2 | SGDID:S000005182 | cspB CPF_2887 |
cspB CPF_2887 |
Clostridium perfringens | 4i0w_d | A0A0H2YU83 | 99.80 | 3.60E-26 | 3.10E-30 | 259.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL238W | KEX2 | SGDID:S000005182 | cspC CDR20291_2146 |
cspC CDR20291_2146 |
Clostridioides difficile | 6mw4_a | C9YNI7 | 99.80 | 2.10E-26 | 1.90E-30 | 265.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL238W | KEX2 | SGDID:S000005182 | aprN |
Subtilisin NAT (EC 3.4.21.62) (Nattokinase) |
3.4.21.62 | Bacillus subtilis | 3vyv_a | P35835 | 99.80 | 1.40E-25 | 1.20E-29 | 234.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL238W | KEX2 | SGDID:S000005182 | PROF |
PROF |
Bacillus | 1wmd_a | Q93UV9 | 100.00 | 5.20E-34 | 4.60E-38 | 318.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL238W | KEX2 | SGDID:S000005182 | apr |
Subtilisin BPN' (EC 3.4.21.62) (Alkaline protease) (Subtilisin DFE) (Subtilisin Novo) |
3.4.21.62 | Bacillus amyloliquefaciens | 1to2_e | P00782 | 99.80 | 1.30E-25 | 1.20E-29 | 235.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL238W | KEX2 | SGDID:S000005182 | patA |
patA |
Prochloron didemni | 3zxy_a | Q52QI9 | 99.80 | 7.90E-25 | 7.00E-29 | 229.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL238W | KEX2 | SGDID:S000005182 | scpA |
C5a peptidase (EC 3.4.21.110) (SCP) |
3.4.21.110 | Streptococcus pyogenes | 1xf1_b | P15926 | 99.90 | 3.50E-27 | 3.00E-31 | 288.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL238W | KEX2 | SGDID:S000005182 | PCSK9 NARC1 PSEC0052 |
Proprotein convertase subtilisin/kexin type 9 (EC 3.4.21.-) (Neural apoptosis-regulated convertase 1) (NARC-1) (Proprotein convertase 9) (PC9) (Subtilisin/kexin-like protease PC9) |
3.4.21.- | Homo sapiens | Heart Disease,Vascular Disease,Aortic Valve Disease 2,Myopathy,Coronary Stenosis,Chronic Ethmoiditis,Inherited Metabolic Disorder,Diabetes Mellitus,Homozygous Familial Hypercholesterolemia,Myocardial Infarction,Defective Apolipoprotein B-100,Sitosterolemia,Corneal Degeneration,Arcus Corneae,Atherosclerosis Susceptibility,Cardiovascular System Disease,Nasopharyngitis,Intermediate Coronary Syndrome,Familial Hypercholesterolemia,Tyrosinemia, Type I,Hypolipoproteinemia,Hypobetalipoproteinemia, Familial, 1,Hypercholesterolemia, Familial, 3,Hypercholesterolemia, Familial, 4,Alcohol Use Disorder,Type 2 Diabetes Mellitus,Cholesterol Level Quantitative Trait Locus 1,Multidrug-Resistant Tuberculosis,Hypobetalipoproteinemia, Familial, 2,Neural Tube Defects,Hyperlipoproteinemia, Type I,Peripheral Artery Disease,Hypercholesterolemia, Familial, 1,Hypertension, Essential,Abetalipoproteinemia,Form Agnosia |
4nmx_b | Q8NBP7 | ENSG00000169174 | PCSK9 | 99.70 | 1.00E-22 | 9.10E-27 | 216.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YNL238W | KEX2 | SGDID:S000005182 | mycP1 MSMEG_0083 MSMEI_0081 |
Mycosin-1 (EC 3.4.21.-) (MycP1 protease) |
Mycolicibacterium smegmatis | 4j94_a | A0QNL1 | 99.90 | 6.40E-29 | 5.50E-33 | 276.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL238W | KEX2 | SGDID:S000005182 | sbt3 Solyc01g087850 |
Subtilisin-like protease SBT3 (EC 3.4.21.-) (LeSBT3) (SlSBT3) (Subtilase 3) |
3.4.21.- | Solanum lycopersicum | 3i6s_b | O82777 | 99.90 | 9.00E-27 | 7.80E-31 | 273.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL238W | KEX2 | SGDID:S000005182 | Proteinase K |
Proteinase K |
Serratia | 2b6n_a | Q3HUQ2 | 99.70 | 1.40E-22 | 1.30E-26 | 211.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL238W | KEX2 | SGDID:S000005182 | FURIN FUR PACE PCSK3 |
Furin (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE) |
3.4.21.75 | Homo sapiens | Diphtheria,Amyloidosis,Ebola Hemorrhagic Fever,Marburg Hemorrhagic Fever,Tracheitis,Coronavirus Infectious Disease,Middle East Respiratory Syndrome,Avian Influenza,Amyloidosis, Finnish Type,Ectodermal Dysplasia,Cerebral Amyloid Angiopathy, Cst3-Related,Refractory Hairy Cell Leukemia,Refractory Hematologic Cancer,Crimean-Congo Hemorrhagic Fever,Cutaneous Anthrax,Anthrax Disease,Colon Adenocarcinoma,Cystic Fibrosis,Noonan Syndrome 1,Borna Disease,Influenza,Aortic Valve Disease 1,Mumps,Brachydactyly, Type D,Severe Acute Respiratory Syndrome,Muscular Dystrophy, Congenital, Due To Integrin Alpha-7 Deficiency,Gastrointestinal Anthrax,Colorectal Cancer,Ectodermal Dysplasia 10b, Hypohidrotic/Hair/Tooth Type, Autosomal Recessive,Murray Valley Encephalitis,Cerebral Amyloid Angiopathy, Itm2b-Related, 2,Hypobetalipoproteinemia, Familial, 1,Cerebral Amyloid Angiopathy, Itm2b-Related, 1,Cone-Rod Dystrophy 2,Disease Of Mental Health,Chikungunya,Inhalation Anthrax,Weill-Marchesani Syndrome,Immune Deficiency Disease,Hypophosphatemic Rickets, Autosomal Dominant,Hypertension, Essential,Stuttering,Tumoral Calcinosis, Hyperphosphatemic, Familial, 1 |
4z2a_a | P09958 | ENSG00000140564 | FURIN | 100.00 | 3.90E-47 | 3.50E-51 | 430.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YNL238W | KEX2 | SGDID:S000005182 | subA |
Subtilase cytotoxin subunit A (EC 3.4.21.-) |
3.4.21.- | Escherichia coli | 2iy9_a | Q6EZC2 | 99.80 | 5.20E-25 | 4.60E-29 | 238.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
YNL238W | KEX2 | SGDID:S000005182 | Protease (EC 3.4.21.64) |
Protease (EC 3.4.21.64) |
Penicillium cyclopium | 5z6o_a | A0A2R2JFW8 | 99.70 | 8.00E-23 | 7.00E-27 | 214.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL238W | KEX2 | SGDID:S000005182 | pagA |
pagA |
Planktothrix agardhii | 4h6w_a | F5B6Y7 | 99.80 | 2.50E-24 | 2.30E-28 | 228.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL238W | KEX2 | SGDID:S000005182 | nisP |
Nisin leader peptide-processing serine protease NisP (EC 3.4.21.-) |
3.4.21.- | Lactococcus lactis | 4mzd_a | Q07596 | 99.90 | 1.70E-28 | 1.50E-32 | 278.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL238W | KEX2 | SGDID:S000005182 | TppII CG3991 |
Tripeptidyl-peptidase 2 (TPP-2) (EC 3.4.14.10) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase II) (TPP-II) (dTPP II) |
3.4.14.10 | Drosophila melanogaster | 3lxu_x | Q9V6K1 | 99.70 | 6.40E-22 | 5.10E-26 | 246.40 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | |||
YNL238W | KEX2 | SGDID:S000005182 | PROK |
Proteinase K (EC 3.4.21.64) (Endopeptidase K) (Tritirachium alkaline proteinase) |
3.4.21.64 | Parengyodontium album | 2pwa_a | P06873 | 99.70 | 3.80E-23 | 3.40E-27 | 216.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL238W | KEX2 | SGDID:S000005182 | lanP BL00930 |
lanP BL00930 |
Bacillus licheniformis | 4zoq_p | Q65DC7 | 99.80 | 1.40E-24 | 1.30E-28 | 233.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL238W | KEX2 | SGDID:S000005182 | PARC_a3481 |
PARC_a3481 |
Pseudoalteromonas arctica | 5yl7_a | A0A290S6P3 | 99.80 | 1.10E-25 | 9.30E-30 | 244.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL238W | KEX2 | SGDID:S000005182 | isp |
isp |
Alkalihalobacillus clausii | 2x8j_d | D0AB41 | 99.80 | 3.30E-25 | 2.90E-29 | 238.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YNL238W | KEX2 | SGDID:S000005182 | TK1675 |
Tk-subtilisin (EC 3.4.21.-) |
3.4.21.- | Thermococcus kodakarensis | 2z2x_a | P58502 | 99.80 | 6.80E-26 | 6.00E-30 | 242.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL238W | KEX2 | SGDID:S000005182 | Extracellular serine protease |
Extracellular serine protease |
Aeromonas sobria | 3wqb_a | Q9L5A4 | 100.00 | 1.10E-42 | 9.30E-47 | 407.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |