Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
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YNL267W | PIK1 | SGDID:S000005211 | PI4KA PIK4 PIK4CA |
Phosphatidylinositol 4-kinase alpha (PI4-kinase alpha) (PI4K-alpha) (PtdIns-4-kinase alpha) (EC 2.7.1.67) (Phosphatidylinositol 4-Kinase III alpha) |
2.7.1.67 | Homo sapiens | Cerebellar Hypoplasia,Hepatitis C,Yunis-Varon Syndrome,Hepatitis,Long Qt Syndrome,Polymicrogyria,Hepatitis C Virus,Polymicrogyria, Bilateral Perisylvian, X-Linked,Mouth Disease,Gastrointestinal Defects And Immunodeficiency Syndrome,Digeorge Syndrome,Velocardiofacial Syndrome,Heparin Cofactor Ii Deficiency,Polymicrogyria, Perisylvian, With Cerebellar Hypoplasia And Arthrogryposis,Lenz-Majewski Hyperostotic Dwarfism,Joubert Syndrome 1,Van Den Ende-Gupta Syndrome |
6bq1_a | P42356 | ENSG00000241973 | PI4KA | 100.00 | 3.30E-59 | 2.80E-63 | 582.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YNL267W | PIK1 | SGDID:S000005211 | MEC1 ESR1 SAD3 YBR136W YBR1012 |
Serine/threonine-protein kinase MEC1 (EC 2.7.11.1) (ATR homolog) (DNA-damage checkpoint kinase MEC1) (Mitosis entry checkpoint protein 1) |
2.7.11.1 | Saccharomyces cerevisiae | 5x6o_c | P38111 | 100.00 | 3.80E-38 | 3.70E-42 | 409.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YNL267W | PIK1 | SGDID:S000005211 | Pi3K59F Dmel\CG5373 DmVps34 dPI3K dVps34 PI(3)K PI3K PI3K-59F PI3K59F Pi3k59F PI3K_59F Pi3K_59F PI[[3]]K PIK359F VPS34 Vps34 vps34 CG5373 Dmel_CG5373 |
Pi3K59F Dmel\CG5373 DmVps34 dPI3K dVps34 PI(3)K PI3K PI3K-59F PI3K59F Pi3k59F PI3K_59F Pi3K_59F PI[[3]]K PIK359F VPS34 Vps34 vps34 CG5373 Dmel_CG5373 |
2.7.1.137 | Drosophila melanogaster | 2x6h_b | Q9W1M7 | 100.00 | 1.60E-61 | 1.50E-65 | 571.90 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | |||
YNL267W | PIK1 | SGDID:S000005211 | PIK3C3 VPS34 |
Phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3-kinase type 3) (PI3K type 3) (PtdIns-3-kinase type 3) (EC 2.7.1.137) (Phosphatidylinositol 3-kinase p100 subunit) (Phosphoinositide-3-kinase class 3) (hVps34) |
2.7.1.137 | Homo sapiens | Myopathy,Alzheimer Disease,Amyotrophic Lateral Sclerosis 1,Parkinson Disease, Late-Onset,Centronuclear Myopathy,Danon Disease,Huntington Disease,Kaposi Sarcoma,Myopathy, Centronuclear, X-Linked,Myopathy, X-Linked, With Excessive Autophagy |
4uwh_a | Q8NEB9 | ENSG00000078142 | PIK3C3 | 100.00 | 2.60E-63 | 2.50E-67 | 578.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YNL267W | PIK1 | SGDID:S000005211 | ATR FRP1 |
Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1) |
2.7.11.1 | Homo sapiens | Lattice Corneal Dystrophy,Chronic Active Epstein-Barr Virus Infection,Lung Large Cell Carcinoma,Cerebellar Disease,Fanconi Anemia, Complementation Group I,Blepharophimosis,Ovarian Cancer,Breast Cancer,Microcephaly,Xeroderma Pigmentosum, Variant Type,Fanconi Anemia, Complementation Group A,Seckel Syndrome,Cutaneous Telangiectasia And Cancer Syndrome, Familial,Autosomal Recessive Cerebellar Ataxia,Nijmegen Breakage Syndrome,Leukemia, Chronic Lymphocytic,Ceroid Lipofuscinosis, Neuronal, 2,Epithelial-Stromal Tgfbi Dystrophy,Ataxia-Telangiectasia,Seckel Syndrome 1,Isolated Growth Hormone Deficiency, Type Ia |
5yz0_b | Q13535 | ENSG00000175054 | ATR | 100.00 | 2.60E-37 | 2.70E-41 | 404.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YNL267W | PIK1 | SGDID:S000005211 | PIK3CA |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.137) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide 3-kinase alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1) |
2.7.1.153,2.7.11.1, | Homo sapiens | Adult Hepatocellular Carcinoma,Breast Papillomatosis,Pancreatic Adenocarcinoma,Skin Melanoma,Heart Disease,Uterine Body Mixed Cancer,Ovarian Carcinosarcoma,Uterine Carcinosarcoma,Endometrial Cancer,Acanthoma,Squamous Cell Carcinoma,Macrodactyly Of Toes,Retinitis Pigmentosa,Brain Stem Glioma,Thyroid Gland Cancer,Lung Cancer Susceptibility 3,Penile Cancer,Penile Benign Neoplasm,Adenoid Cystic Carcinoma,Carcinosarcoma,Cowden Syndrome,Suppression Of Tumorigenicity 12,Melanoma,Plasma Cell Neoplasm,Erdheim-Chester Disease,Thyroid Gland Anaplastic Carcinoma,Diabetes Mellitus,Adenoma,Cowden Syndrome 1,Breast Juvenile Papillomatosis,Rectum Adenocarcinoma,Bilateral Breast Cancer,Hemihyperplasia-Multiple Lipomatosis Syndrome,Uterine Corpus Cancer,Hepatitis B,Clear Cell Adenocarcinoma,Familiar Ovarian Carcinoma,Vulvar Disease,Rasopathy,Nephrogenic Systemic Fibrosis,Vulva Squamous Cell Carcinoma,Intestinal Benign Neoplasm,Stroke, Ischemic,Epiglottis Neoplasm,Malignant Ovarian Surface Epithelial-Stromal Neoplasm,Ovary Epithelial Cancer,Anus Basaloid Carcinoma,Costello Syndrome,Ovarian Epithelial Cancer,Congenital Lipomatous Overgrowth, Vascular Malformations, And Epidermal Nevi,Hepatitis,Facial Infiltrating Lipomatosis,Pik3ca-Related Overgrowth Spectrum,Endocervical Carcinoma,Colon Adenocarcinoma,Adenosquamous Lung Carcinoma,Vulva Cancer,Adenosquamous Carcinoma,Neuroblastoma,Myoepithelial Carcinoma,Pilocytic Astrocytoma,Nevus, Epidermal,Schimmelpenning-Feuerstein-Mims Syndrome,Malignant Spiradenoma,Glioma,Frontal Convexity Meningioma,Leukemia, Acute Myeloid,Thyroid Hurthle Cell Adenoma,Hemimegalencephaly,Kidney Cancer,Capillary Malformation Of The Lower Lip, Lymphatic Malformation Of Face And Neck, Asymmetry Of Face And Limbs, And Partial/Generalized Overgrowth,Cowden Syndrome 5,Rosette-Forming Glioneuronal Tumor,Urinary Tract Obstruction,Mulchandani-Bhoj-Conlin Syndrome,Thyroid Carcinoma,Bladder Cancer,Segmental Progressive Overgrowth Syndrome With Fibroadipose Hyperplasia,Ovarian Clear Cell Adenocarcinoma,Ethmoid Sinus Adenocarcinoma,Epithelial-Myoepithelial Carcinoma,Brain Cancer,Pik3ca-Related Segmental Overgrowth,Lung Oat Cell Carcinoma,Pik3ca-Related Overgrowth Syndrome,Prostate Squamous Cell Carcinoma,Oropharynx Cancer,Eccrine Papillary Adenoma,Cervix Carcinoma,Clear Cell Adenofibroma,Anal Squamous Cell Carcinoma,Lip And Oral Cavity Cancer,Diaphragmatic Eventration,Ovarian Cancer,Adenocarcinoma,In Situ Carcinoma,Tuberous Sclerosis,Female Reproductive Endometrioid Cancer,Intraductal Breast Benign Neoplasm,Breast Carcinoma In Situ,Breast Cancer,Glioblastoma,Tonsil Cancer,Squamous Cell Carcinoma, Head And Neck,Cellular Myxoid Liposarcoma,High Grade Glioma,Gliosarcoma,Giant Cell Glioblastoma,Colorectal Cancer,Cystic Lymphangioma,Hypertrophy Of Breast,Ovarian Serous Cystadenocarcinoma,Endometrial Serous Adenocarcinoma,Cystadenocarcinoma,Patella, Chondromalacia Of,Serous Cystadenocarcinoma,Gallbladder Cancer,Hepatocellular Carcinoma,Endometrioid Ovary Carcinoma,Megalencephaly-Capillary Malformation-Polymicrogyria Syndrome,Lipomatosis,Ovarian Clear Cell Adenofibroma,Ovarian Mixed Germ Cell Neoplasm,Macrodactyly Of Fingers, Unilateral,Macrodactyly Of Toes, Unilateral,Anus Cancer,Angiomatosis,Rhabdomyosarcoma,Megalencephaly,Hepatitis C Virus,Orbit Embryonal Rhabdomyosarcoma,Immunodeficiency 14,Sarcoma,Liposarcoma,Skin Carcinoma,Gastric Cancer,Breast Adenocarcinoma,Lymphangioma,Prostate Cancer,Cholangiocarcinoma,Gallbladder Adenocarcinoma,Proteus Syndrome,Cervical Cancer,Ovarian Cystadenocarcinoma,Mixed Cell Type Cancer,Glycogen Storage Disease Ii,Adrenal Cortical Carcinoma,Keratosis,Dermatosis Papulosa Nigra,Ovary Adenocarcinoma,Gastric Adenocarcinoma,Cervical Squamous Cell Carcinoma,Lynch Syndrome,Hidradenoma,Lung Squamous Cell Carcinoma,Adrenal Carcinoma,Thyroid Gland Follicular Carcinoma,Bladder Urothelial Carcinoma,Lymphoma, Non-Hodgkin, Familial,Keratosis, Seborrheic,Renal Cell Carcinoma, Papillary, 1,Small Cell Cancer Of The Lung,Esophageal Cancer,Sturge-Weber Syndrome,Meningioma, Radiation-Induced,Mantle Cell Lymphoma,Renal Cell Carcinoma, Nonpapillary,Large Intestine Adenocarcinoma,Ovarian Clear Cell Carcinoma,Uterine Corpus Endometrial Carcinoma,Endocervical Adenocarcinoma,Nasopharyngeal Carcinoma,Hypertelorism,Meningioma, Familial,Lymphoma,Pre-Malignant Neoplasm,Ductal Carcinoma In Situ,Estrogen-Receptor Positive Breast Cancer,Kaposi Sarcoma,Colitis,Klippel-Trenaunay-Weber Syndrome,Parameningeal Embryonal Rhabdomyosarcoma,Myeloma, Multiple,Medulloblastoma,Megalencephaly, Autosomal Dominant,Macrodactyly,Melanoma, Uveal,Neuroblastoma 1,Lung Cancer,Oculoectodermal Syndrome,Pancreatic Cancer |
4jps_a | P42336 | ENSG00000121879 | PIK3CA | 100.00 | 6.50E-62 | 6.30E-66 | 597.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YNL267W | PIK1 | SGDID:S000005211 | PI4KB PIK4CB |
Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) (NPIK) (PI4K92) (PI4KIII) |
2.7.1.67 | Homo sapiens | Poliomyelitis,Nonparalytic Poliomyelitis,Mouth Disease,Lowe Oculocerebrorenal Syndrome,Polycystic Kidney Disease 3 With Or Without Polycystic Liver Disease |
5c46_e | Q9UBF8 | ENSG00000143393 | PI4KB | 100.00 | 4.40E-65 | 4.40E-69 | 583.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YNL267W | PIK1 | SGDID:S000005211 | Pik3cb |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) (PI3K-beta) (PI3Kbeta) (PtdIns-3-kinase subunit beta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta) (PtdIns-3-kinase subunit p110-beta) (p110beta) |
2.7.1.153 | Mus musculus | 4bfr_a | Q8BTI9 | 100.00 | 6.10E-64 | 5.90E-68 | 609.30 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |