| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YOR117W | RPT5 | SGDID:S000005643 | VCP |
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP) |
3.6.4.6 | Homo sapiens | Muscular Disease,Amyotrophic Lateral Sclerosis 6 With Or Without Frontotemporal Dementia,Zellweger Syndrome,Supranuclear Palsy, Progressive, 1,Retinitis Pigmentosa,Myopathy,Myofibrillar Myopathy,Muscle Tissue Disease,Neuromuscular Disease,Alzheimer Disease,Nominal Aphasia,Amyotrophic Lateral Sclerosis 1,Myositis,Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 1,Early-Onset, Autosomal Dominant Alzheimer Disease,Amyotrophic Lateral Sclerosis 8,Lateral Sclerosis,Motor Neuron Disease,Autosomal Dominant Limb-Girdle Muscular Dystrophy,Muscular Dystrophy,Movement Disease,Progressive Non-Fluent Aphasia,Dyscalculia,Inclusion Body Myopathy With Early-Onset Paget Disease Of Bone With Or Without Frontotemporal Dementia 1,Hereditary Spastic Paraplegia,Cystic Fibrosis,Machado-Joseph Disease,Spastic Paraplegia-Paget Disease Of Bone Syndrome,Adult-Onset Distal Myopathy Due To Vcp Mutation,Multisystem Proteinopathy,Dementia,Paget'S Disease Of Bone,Cockayne Syndrome,Alexia,Inclusion Body Myopathy With Early-Onset Paget Disease With Or Without Frontotemporal Dementia 1,Charcot-Marie-Tooth Disease,Parkinson Disease, Late-Onset,Perry Syndrome,Speech And Communication Disorders,Progressive Muscular Atrophy,Tooth Disease,Pick Disease Of Brain,Werner Syndrome,Autosomal Dominant Cerebellar Ataxia,Neuronal Ceroid Lipofuscinosis,Mammary Paget'S Disease,Breast Adenocarcinoma,Disease Of Mental Health,Dementia, Lewy Body,Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 6,Fanconi Anemia, Complementation Group G,Nonaka Myopathy,Alzheimer Disease 7,Amyotrophic Lateral Sclerosis 16, Juvenile,Ehlers-Danlos Syndrome, Spondylodysplastic Type, 3,Inclusion Body Myopathy With Paget Disease Of Bone And Frontotemporal Dementia,Aphasia,Writing Disorder,Inclusion Body Myositis,Associative Agnosia,Amyotrophic Lateral Sclerosis Type 6,Amyotrophic Lateral Sclerosis Type 14,Agraphia,Charcot-Marie-Tooth Disease, Axonal, Type 2e,Frontotemporal Dementia,Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 7 |
4ko8_a | P55072 | ENSG00000165280 | VCP | 98.00 | 2.10E-09 | 1.80E-13 | 108.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YOR117W | RPT5 | SGDID:S000005643 | spas CG5977 |
Spastin (EC 5.6.1.1) (D-Spastin) (Dm-Spastin) (Dspastin) |
5.6.1.1 | Drosophila melanogaster | 3b9p_a | Q8I0P1 | 96.60 | 5.90E-06 | 5.50E-10 | 74.20 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | |||
| YOR117W | RPT5 | SGDID:S000005643 | NSF |
Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF) |
3.6.4.6 | Cricetulus griseus | 1d2n_a | P18708 | 95.80 | 9.20E-05 | 7.40E-09 | 67.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YOR117W | RPT5 | SGDID:S000005643 | PRE1 YER012W |
Proteasome subunit beta type-4 (Macropain subunit C11) (Multicatalytic endopeptidase complex subunit C11) (Proteasome component C11) (Proteinase YSCE subunit 11) |
3.4.25.1 | Saccharomyces cerevisiae | 6fvt_k | P22141 | 99.00 | 2.50E-14 | 2.20E-18 | 141.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YOR117W | RPT5 | SGDID:S000005643 | pch-2 F10B5.5 |
Putative pachytene checkpoint protein 2 |
Caenorhabditis elegans | 4xgu_b | Q09535 | 95.70 | 0.0001 | 9.30E-09 | 70.30 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | ||||
| YOR117W | RPT5 | SGDID:S000005643 | AFG3L2 |
AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein) |
3.4.24.- | Homo sapiens | Progressive Myoclonus Epilepsy,Dystonia 9,Spasticity,Epilepsy,Optic Nerve Disease,Episodic Ataxia,Chronic Progressive External Ophthalmoplegia,Hereditary Spastic Paraplegia,Cerebellar Ataxia Type 41,Cerebellar Ataxia Type 48,Choreatic Disease,Sensorineural Hearing Loss,Spastic Paraparesis,Cerebellar Disease,Dystonia,Neuropathy,Early Myoclonic Encephalopathy,Spinocerebellar Ataxia 30,Spinocerebellar Ataxia, Autosomal Recessive 14,Myoclonus,Spinocerebellar Ataxia 29,Alacrima, Achalasia, And Mental Retardation Syndrome,Autosomal Dominant Cerebellar Ataxia,Disease Of Mental Health,Spinocerebellar Ataxia 28,Optic Atrophy With Or Without Deafness, Ophthalmoplegia, Myopathy, Ataxia, And Neuropathy,Dentatorubral-Pallidoluysian Atrophy,Aceruloplasminemia,Optic Atrophy 5,Spinocerebellar Ataxia, Autosomal Recessive 8,Optic Atrophy 9,Spinocerebellar Ataxia 15,Perrault Syndrome,Spastic Ataxia 5, Autosomal Recessive,Spastic Ataxia 4,Spastic Ataxia 5,Hereditary Ataxia,Spastic Ataxia,Spastic Paraplegia 7, Autosomal Recessive,Spinocerebellar Ataxia 21,Spinocerebellar Ataxia 18,Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis,Optic Atrophy 10 With Or Without Ataxia, Mental Retardation, And Seizures,Ptosis,Optic Atrophy 12,Striatal Degeneration, Autosomal Dominant 2,Kearns-Sayre Syndrome,3-Methylglutaconic Aciduria, Type Iii |
6nyy_b | Q9Y4W6 | ENSG00000141385 | AFG3L2 | 98.00 | 2.20E-09 | 1.80E-13 | 110.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YOR117W | RPT5 | SGDID:S000005643 | MYCTH_2311706 |
MYCTH_2311706 |
Myceliophthora thermophila | 5ubv_a | G2QPI5 | 97.00 | 1.30E-06 | 1.30E-10 | 74.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YOR117W | RPT5 | SGDID:S000005643 | RPT1 CIM5 YTA3 YKL145W |
26S proteasome regulatory subunit 7 homolog (Protein CIM5) (Tat-binding homolog 3) |
Saccharomyces cerevisiae | 3vlf_d | P33299 | 95.30 | 0.00025 | 2.30E-08 | 51.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YOR117W | RPT5 | SGDID:S000005643 | Psmc4 Tbp7 |
26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (CIP21) (MB67-interacting protein) (MIP224) (Proteasome 26S subunit ATPase 4) (Tat-binding protein 7) (TBP-7) |
Mus musculus | 3aji_b | P54775 | 96.10 | 3.60E-05 | 3.40E-09 | 54.90 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | ||||
| YOR117W | RPT5 | SGDID:S000005643 | FIGNL1 |
Fidgetin-like protein 1 (EC 3.6.4.-) |
3.6.4.- | Homo sapiens | 3d8b_a | Q6PIW4 | ENSG00000132436 | FIGNL1 | 97.50 | 8.90E-08 | 7.80E-12 | 92.00 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YOR117W | RPT5 | SGDID:S000005643 | VPS4B SKD1 VPS42 MIG1 |
Vacuolar protein sorting-associated protein 4B (EC 3.6.4.6) (Cell migration-inducing gene 1 protein) (Suppressor of K(+) transport growth defect 1) (Protein SKD1) |
3.6.4.6 | Homo sapiens | Parotid Gland Cancer,Submandibular Gland Cancer,Dentin Dysplasia,Submandibular Gland Disease,Dentin Dysplasia, Type I |
1xwi_a | O75351 | ENSG00000119541 | VPS4B | 97.40 | 1.50E-07 | 1.30E-11 | 87.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YOR117W | RPT5 | SGDID:S000005643 | mpa Rv2115c MTCY261.11c |
Proteasome-associated ATPase (AAA ATPase forming ring-shaped complexes) (ARC) (Mycobacterial proteasome ATPase) |
Mycobacterium tuberculosis | 3m9b_f | P9WQN5 | 96.90 | 2.00E-06 | 1.50E-10 | 79.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YOR117W | RPT5 | SGDID:S000005643 | SPG7 CAR CMAR PGN |
Paraplegin (EC 3.4.24.-) (Cell matrix adhesion regulator) (Spastic paraplegia 7 protein) |
3.4.24.- | Homo sapiens | Paraplegia,Spastic Paraplegia 42, Autosomal Dominant,Neuropathy, Hereditary Motor And Sensory, Type Via, With Optic Atrophy,Seizure Disorder,Spasticity,Optic Nerve Disease,Spinocerebellar Ataxia, Autosomal Recessive 24,Mitochondrial Myopathy,Spastic Paraplegia 50, Autosomal Recessive,Spinal Muscular Atrophy,Hereditary Spastic Paraplegia 30,Hereditary Spastic Paraplegia 51,Hereditary Spastic Paraplegia 72,Secondary Hyperparathyroidism,Spastic Paraplegia 17, Autosomal Dominant,Spastic Paraplegia 15, Autosomal Recessive,Proximal Spinal Muscular Atrophy,Chronic Progressive External Ophthalmoplegia,Spastic Paraplegia 5a, Autosomal Recessive,Spastic Paraplegia 56, Autosomal Recessive,Spastic Paraplegia 49, Autosomal Recessive,Spastic Paraplegia 54, Autosomal Recessive,Spastic Paraplegia 55, Autosomal Recessive,Hereditary Spastic Paraplegia,Motor Peripheral Neuropathy,Ocular Motility Disease,Complex Hereditary Spastic Paraplegia,Mitochondrial Complex Iii Deficiency, Nuclear Type 2,Optic Atrophy 3, Autosomal Dominant,Optic Atrophy 1,Spastic Paraparesis,Cerebellar Disease,Mitochondrial Disorders,Neuropathy,Cranial Nerve Disease,Spastic Paraplegia 20, Autosomal Recessive,Early Myoclonic Encephalopathy,Peripheral Nervous System Disease,Polyneuropathy,Spinocerebellar Ataxia, Autosomal Recessive 14,Spastic Paraplegia 28, Autosomal Recessive,Autosomal Dominant Cerebellar Ataxia,Hypoparathyroidism,Spastic Paraplegia 48, Autosomal Recessive,Spastic Paraplegia 8, Autosomal Dominant,Hutchinson-Gilford Progeria Syndrome,Disease Of Mental Health,Spinocerebellar Ataxia 28,Spastic Paraplegia 31, Autosomal Dominant,Spastic Paraplegia 16, X-Linked,Spastic Paraplegia 63, Autosomal Recessive,Spastic Paraplegia 10, Autosomal Dominant,Dentatorubral-Pallidoluysian Atrophy,Spastic Paraplegia 11, Autosomal Recessive,Optic Atrophy 5,Spastic Paraplegia 14, Autosomal Recessive,Spastic Paraplegia 3, Autosomal Dominant,Spastic Paraplegia 47, Autosomal Recessive,Spastic Paraplegia 4, Autosomal Dominant,Spastic Paraplegia 13, Autosomal Dominant,Spastic Paraplegia 18, Autosomal Recessive,Spastic Paraplegia 32, Autosomal Recessive,Primary Lateral Sclerosis, Adult, 1,Spastic Paraplegia 39, Autosomal Recessive,Optic Atrophy 9,Spastic Paraplegia 46, Autosomal Recessive,Spastic Paraplegia 35, Autosomal Recessive,Perrault Syndrome,Masa Syndrome,Spastic Ataxia 5,Autosomal Recessive Cerebellar Ataxia,Hereditary Ataxia,Spastic Ataxia,Spastic Paraplegia 7, Autosomal Recessive,Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis,Leber Hereditary Optic Neuropathy, Modifier Of,Charcot-Marie-Tooth Disease, Axonal, Type 2e,Spastic Paraplegia 2, X-Linked,Familial Hypocalciuric Hypercalcemia,Behr Syndrome,Kearns-Sayre Syndrome,Spastic Paraplegia 6, Autosomal Dominant,3-Methylglutaconic Aciduria, Type Iii |
2qz4_a | Q9UQ90 | ENSG00000197912 | SPG7 | 96.80 | 3.00E-06 | 2.80E-10 | 73.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YOR117W | RPT5 | SGDID:S000005643 | POLG |
Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion protein 4); Capsid protein VP2 (P1B) (Virion protein 2); Capsid protein VP3 (P1C) (Virion protein 3); Capsid protein VP1 (P1D) (Virion protein 1); P2; Protease 2A (P2A) (EC 3.4.22.29) (Picornain 2A) (Protein 2A); Protein 2B (P2B); Protein 2C (P2C) (EC 3.6.1.15); P3; Protein 3AB; Protein 3A (P3A); Viral protein genome-linked (VPg) (Protein 3B) (P3B); Protein 3CD (EC 3.4.22.28); Protease 3C (EC 3.4.22.28) (Picornain 3C) (P3C); RNA-directed RNA polymerase (RdRp) (EC 2.7.7.48) (3D polymerase) (3Dpol) (Protein 3D) (3D)] |
2.7.7.48,3.4.22.28,3.4.22.29,3.6.1.15, | Human enterovirus | 5grb_b | B9VUU3 | 95.00 | 0.0004 | 3.70E-08 | 58.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YOR117W | RPT5 | SGDID:S000005643 | RPT5 YTA1 YOR117W O3258 YOR3258W |
26S proteasome regulatory subunit 6A (Tat-binding protein homolog 1) (TBP-1) |
Saccharomyces cerevisiae | 3whk_e | P33297 | 97.80 | 1.40E-08 | 1.30E-12 | 89.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YOR117W | RPT5 | SGDID:S000005643 | VPS4 CSC1 DID6 END13 GRD13 VPL4 VPT10 YPR173C P9705.10 |
Vacuolar protein sorting-associated protein 4 (DOA4-independent degradation protein 6) (Protein END13) (Vacuolar protein-targeting protein 10) |
Saccharomyces cerevisiae | 3eie_a | P52917 | 97.30 | 3.00E-07 | 2.70E-11 | 85.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YOR117W | RPT5 | SGDID:S000005643 | pan MJ1176 |
Proteasome-activating nucleotidase (PAN) (Proteasomal ATPase) (Proteasome regulatory ATPase) (Proteasome regulatory particle) |
Methanocaldococcus jannaschii | 3h43_i | Q58576 | 96.40 | 1.30E-05 | 1.10E-09 | 61.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YOR117W | RPT5 | SGDID:S000005643 | pan PH0201 |
Proteasome-activating nucleotidase (PAN) (Proteasomal ATPase) (Proteasome regulatory ATPase) (Proteasome regulatory particle) |
Pyrococcus horikoshii | 5eqt_a | O57940 | 96.70 | 3.70E-06 | 3.60E-10 | 72.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YOR117W | RPT5 | SGDID:S000005643 | PSMC6 SUG2 |
26S proteasome regulatory subunit 10B (26S proteasome AAA-ATPase subunit RPT4) (Proteasome 26S subunit ATPase 6) (Proteasome subunit p42) |
Homo sapiens | Alzheimer Disease,Cystic Fibrosis,Ehrlichiosis,Pheochromocytoma |
5vfu_e | P62333 | ENSG00000100519 | PSMC6 | 99.20 | 1.80E-15 | 1.60E-19 | 146.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YOR117W | RPT5 | SGDID:S000005643 | SPAST ADPSP FSP2 KIAA1083 SPG4 |
Spastin (EC 5.6.1.1) (Spastic paraplegia 4 protein) |
5.6.1.1 | Homo sapiens | Paraplegia,Chromosome 1q21.1 Duplication Syndrome,Dystonia 9,Spastic Paraplegia 42, Autosomal Dominant,Zellweger Syndrome,Seizure Disorder,Spasticity,Amyotrophic Lateral Sclerosis 1,Motor Neuron Disease,Hereditary Spastic Paraplegia 30,Hereditary Spastic Paraplegia 72,Spastic Paraplegia 17, Autosomal Dominant,Spastic Paraplegia 15, Autosomal Recessive,Spastic Paraplegia 5a, Autosomal Recessive,Spastic Paraplegia 56, Autosomal Recessive,Hereditary Spastic Paraplegia,Spastic Paraplegia 43, Autosomal Recessive,Pure Hereditary Spastic Paraplegia,Spastic Paraparesis,Spastic Paraplegia 4,Chromosome 17p13.3, Centromeric, Duplication Syndrome,Spastic Paraplegia 26, Autosomal Recessive,Spastic Paraplegia 20, Autosomal Recessive,Spastic Paraplegia 41, Autosomal Dominant,Spastic Diplegia,Spastic Paraplegia 48, Autosomal Recessive,Spastic Paraplegia 8, Autosomal Dominant,Disease Of Mental Health,Spastic Paraplegia 33, Autosomal Dominant,Spastic Paraplegia 31, Autosomal Dominant,Neuropathy, Hereditary Sensory, Type Id,Spastic Paraplegia 16, X-Linked,Spastic Paraplegia 61, Autosomal Recessive,Spastic Paraplegia 10, Autosomal Dominant,Spastic Paraplegia 11, Autosomal Recessive,Spastic Paraplegia 12, Autosomal Dominant,Spastic Paraplegia 14, Autosomal Recessive,Spastic Paraplegia 3, Autosomal Dominant,Spastic Paraplegia 47, Autosomal Recessive,Spastic Paraplegia 4, Autosomal Dominant,Spastic Paraplegia 13, Autosomal Dominant,Myopathy, Proximal, With Ophthalmoplegia,Spastic Paraplegia 39, Autosomal Recessive,Spastic Paraplegia 46, Autosomal Recessive,Masa Syndrome,Charcot-Marie-Tooth Disease, Axonal, Type 2e,Spastic Paraplegia 2, X-Linked,Spastic Paraplegia 6, Autosomal Dominant |
5z6r_a | Q9UBP0 | ENSG00000021574 | SPAST | 97.30 | 1.90E-07 | 1.70E-11 | 91.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YOR117W | RPT5 | SGDID:S000005643 | mpa MRA_2130 |
Proteasome-associated ATPase (AAA ATPase forming ring-shaped complexes) (ARC) (Mycobacterial proteasome ATPase) |
Mycobacterium tuberculosis | 5kzf_k | A5U4E1 | 96.30 | 2.20E-05 | 2.00E-09 | 78.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YOR117W | RPT5 | SGDID:S000005643 | MSP1 YTA4 YGR028W |
Outer mitochondrial transmembrane helix translocase (EC 7.4.2.-) (Mitochondrial sorting of proteins) (Tat-binding homolog 4) |
7.4.2.- | Saccharomyces cerevisiae | 5w0t_a | P28737 | 96.00 | 5.40E-05 | 5.00E-09 | 68.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YOR117W | RPT5 | SGDID:S000005643 | DNA helicase (EC 3.6.4.12) |
DNA helicase (EC 3.6.4.12) |
3.6.4.12 | Bacillus phage | 3bh0_a | Q38152 | 95.70 | 0.0001 | 9.40E-09 | 67.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YOR117W | RPT5 | SGDID:S000005643 | figl-1 F32D1.1 |
Fidgetin-like protein 1 (EC 3.6.4.-) (Fidgetin homolog) |
3.6.4.- | Caenorhabditis elegans | 4l15_a | O16299 | 97.10 | 8.20E-07 | 7.40E-11 | 83.00 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | |||
| YOR117W | RPT5 | SGDID:S000005643 | PSMC4 MIP224 TBP7 |
26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (MB67-interacting protein) (MIP224) (Proteasome 26S subunit ATPase 4) (Tat-binding protein 7) (TBP-7) |
Homo sapiens | Timothy Syndrome,Erythromelalgia,Episodic Ataxia,Cystic Fibrosis,Episodic Ataxia, Type 2,Brugada Syndrome |
2dvw_b | P43686 | ENSG00000013275 | PSMC4 | 96.10 | 3.60E-05 | 3.40E-09 | 54.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YOR117W | RPT5 | SGDID:S000005643 | SEM1 C7orf76 DSS1 SHFDG1 SHFM1 |
26S proteasome complex subunit SEM1 (26S proteasome complex subunit DSS1) (Deleted in split hand/split foot protein 1) (Split hand/foot deleted protein 1) (Split hand/foot malformation type 1 protein) |
Homo sapiens | Eyelid Carcinoma,Orofacial Cleft 4,Split Hand-Foot Malformation,Isolated Split Hand-Split Foot Malformation,Split-Hand/Foot Malformation 1 With Sensorineural Hearing Loss, Autosomal Recessive,Skin Squamous Cell Carcinoma,Split-Hand/Foot Malformation 6,Paranoid Personality Disorder,Shoulder Impingement Syndrome,Fanconi Anemia, Complementation Group A,Split-Hand/Foot Malformation 4,Split-Hand/Foot Malformation 1,Citrullinemia, Type Ii, Neonatal-Onset,Chromosome 2q35 Duplication Syndrome,Split-Hand/Foot Malformation 5,Split-Hand/Foot Malformation 3,Attention Deficit-Hyperactivity Disorder,Split-Hand/Foot Malformation 2 |
6msb_e | P60896 | ENSG00000127922 | SEM1 | 98.50 | 3.40E-11 | 3.00E-15 | 118.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YOR117W | RPT5 | SGDID:S000005643 | KATNAL1 |
Katanin p60 ATPase-containing subunit A-like 1 (Katanin p60 subunit A-like 1) (EC 5.6.1.1) (p60 katanin-like 1) |
5.6.1.1 | Homo sapiens | 13q12.3 Microdeletion Syndrome,Microcephaly,Hypertrichosis Universalis Congenita, Ambras Type,Gluten Allergy,Joubert Syndrome 26 |
6b5c_a | Q9BW62 | ENSG00000102781 | KATNAL1 | 96.50 | 8.00E-06 | 7.40E-10 | 74.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YOR117W | RPT5 | SGDID:S000005643 | MSMEG_0858 |
MSMEG_0858 |
Mycolicibacterium smegmatis | 5e7p_a | A0QQS4 | 97.50 | 6.00E-08 | 5.10E-12 | 102.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YOR117W | RPT5 | SGDID:S000005643 | PRE7 PRS3 PTS1 YBL041W YBL0407 |
Proteasome subunit beta type-6 (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) |
3.4.25.1 | Saccharomyces cerevisiae | 6fvy_m | P23724 | 100.00 | 1.30E-40 | 1.10E-44 | 340.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YOR117W | RPT5 | SGDID:S000005643 | PSMD2 TRAP2 |
26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2) |
Homo sapiens | Angelman Syndrome,Cystic Fibrosis |
6msb_f | Q13200 | ENSG00000175166 | PSMD2 | 99.90 | 9.40E-30 | 7.70E-34 | 260.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YOR117W | RPT5 | SGDID:S000005643 | PSMD14 POH1 |
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (26S proteasome-associated PAD1 homolog 1) |
3.4.19.- | Homo sapiens | Angelman Syndrome,Cystic Fibrosis,Autosomal Dominant Cerebellar Ataxia |
5vft_c | O00487 | ENSG00000115233 | PSMD14 | 97.60 | 3.00E-08 | 2.70E-12 | 94.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YOR117W | RPT5 | SGDID:S000005643 | mei-1 T01G9.5 |
Meiotic spindle formation protein mei-1 (EC 5.6.1.1) (Katanin p60 ATPase-containing subunit A1) (Katanin p60 subunit A1) (p60 katanin) |
5.6.1.1 | Caenorhabditis elegans | 6b5d_a | P34808 | 97.20 | 4.10E-07 | 3.80E-11 | 83.50 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | |||
| YOR117W | RPT5 | SGDID:S000005643 | PSMD4 MCB1 |
26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10) (26S proteasome regulatory subunit S5A) (Antisecretory factor 1) (AF) (ASF) (Multiubiquitin chain-binding protein) |
Homo sapiens | Alzheimer Disease,Angelman Syndrome,Cystic Fibrosis,Cholera,Encephalopathy, Familial, With Neuroserpin Inclusion Bodies,Inflammatory Bowel Disease |
5vft_b | P55036 | ENSG00000159352 | PSMD4 | 99.30 | 3.40E-16 | 3.00E-20 | 151.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YOR117W | RPT5 | SGDID:S000005643 | radA spr0025 |
DNA repair protein RadA (EC 3.6.4.-) (Branch migration protein RadA) |
3.6.4.- | Streptococcus pneumoniae | 5lkm_a | Q8DRP0 | 96.50 | 9.20E-06 | 8.20E-10 | 79.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YOR117W | RPT5 | SGDID:S000005643 | RCA At2g39730 T5I7.3 |
Ribulose bisphosphate carboxylase/oxygenase activase, chloroplastic (RA) (RuBisCO activase) |
Arabidopsis thaliana | 4w5w_a | P10896 | 96.70 | 4.20E-06 | 3.70E-10 | 80.80 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | ||||
| YOR117W | RPT5 | SGDID:S000005643 | RPT6 CIM3 CRL3 SUG1 TBPY TBY1 YGL048C |
26S proteasome regulatory subunit 8 homolog (Protein CIM3) (Protein SUG1) (Tat-binding protein TBY1) |
Saccharomyces cerevisiae | 6ef1_j | Q01939 | 97.30 | 2.50E-07 | 2.40E-11 | 81.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YOR117W | RPT5 | SGDID:S000005643 | ftsH TM_0580 |
ATP-dependent zinc metalloprotease FtsH (EC 3.4.24.-) |
3.4.24.- | Thermotoga maritima | 2ce7_b | Q9WZ49 | 97.60 | 4.10E-08 | 3.60E-12 | 98.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YOR117W | RPT5 | SGDID:S000005643 | Ahos_1335 |
Ahos_1335 |
Acidianus hospitalis | 4lcb_a | F4B4B0 | 96.70 | 4.70E-06 | 4.30E-10 | 78.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YOR117W | RPT5 | SGDID:S000005643 | RPT3 YNT1 YTA2 YDR394W D9509.14 |
26S proteasome regulatory subunit 6B homolog (Protein YNT1) (Tat-binding homolog 2) |
Saccharomyces cerevisiae | 2dzn_f | P33298 | 95.40 | 0.0002 | 1.80E-08 | 51.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YOR117W | RPT5 | SGDID:S000005643 | RPT4 CRL13 PCS1 SUG2 YOR259C |
26S proteasome subunit RPT4 (26S protease subunit SUG2) (Proteasomal cap subunit) |
Saccharomyces cerevisiae | 6ef0_l | P53549 | 97.40 | 1.00E-07 | 9.80E-12 | 84.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YOR117W | RPT5 | SGDID:S000005643 | ftsH TTHA1492 |
ATP-dependent zinc metalloprotease FtsH (EC 3.4.24.-) |
3.4.24.- | Thermus thermophilus | 1iy2_a | Q5SI82 | 96.90 | 1.60E-06 | 1.50E-10 | 77.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YOR117W | RPT5 | SGDID:S000005643 | ftsH aq_936 |
ATP-dependent zinc metalloprotease FtsH (EC 3.4.24.-) |
3.4.24.- | Aquifex aeolicus | 6gcn_b | O67077 | 97.40 | 1.70E-07 | 1.50E-11 | 93.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YOR117W | RPT5 | SGDID:S000005643 | ftsH HP_1069 |
ATP-dependent zinc metalloprotease FtsH (EC 3.4.24.-) |
3.4.24.- | Helicobacter pylori | 2r65_b | P71408 | 96.70 | 3.90E-06 | 3.60E-10 | 73.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YOR117W | RPT5 | SGDID:S000005643 | PSMD13 |
26S proteasome non-ATPase regulatory subunit 13 (26S proteasome regulatory subunit RPN9) (26S proteasome regulatory subunit S11) (26S proteasome regulatory subunit p40.5) |
Homo sapiens | Histrionic Personality Disorder |
5vft_a | Q9UNM6 | ENSG00000185627 | PSMD13 | 98.50 | 4.40E-11 | 3.90E-15 | 115.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YOR117W | RPT5 | SGDID:S000005643 | SCRG_02514 |
SCRG_02514 |
Saccharomyces cerevisiae | 6az0_e | B3LL85 | 97.60 | 3.10E-08 | 2.70E-12 | 97.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YOR117W | RPT5 | SGDID:S000005643 | PRE2 DOA3 PRG1 YPR103W P8283.10 |
Proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain subunit PRE2) (Multicatalytic endopeptidase complex subunit PRE2) (Proteasome component PRE2) (Proteinase YSCE subunit PRE2) |
3.4.25.1 | Saccharomyces cerevisiae | 5mp9_l | P30656 | 98.30 | 1.40E-10 | 1.30E-14 | 114.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YOR117W | RPT5 | SGDID:S000005643 | PSMD8 |
26S proteasome non-ATPase regulatory subunit 8 (26S proteasome regulatory subunit RPN12) (26S proteasome regulatory subunit S14) (p31) |
Homo sapiens | Cystic Fibrosis |
5vfu_d | P48556 | ENSG00000099341 | PSMD8 | 98.80 | 1.20E-12 | 1.10E-16 | 127.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YOR117W | RPT5 | SGDID:S000005643 | RCA1 |
Ribulose bisphosphate carboxylase/oxygenase activase 1, chloroplastic (RA 1) (RuBisCO activase 1) |
Nicotiana tabacum | 3t15_a | Q40460 | 96.20 | 2.70E-05 | 2.30E-09 | 72.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YOR117W | RPT5 | SGDID:S000005643 | pan AF_1976 |
Proteasome-activating nucleotidase (PAN) (Proteasomal ATPase) (Proteasome regulatory ATPase) (Proteasome regulatory particle) |
Archaeoglobus fulgidus | 2wg5_h | O28303 | 96.60 | 7.40E-06 | 6.00E-10 | 65.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YOR117W | RPT5 | SGDID:S000005643 | PSMC5 SUG1 |
26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG) |
Homo sapiens | Cystic Fibrosis,Cockayne Syndrome,Mulibrey Nanism |
2krk_a | P62195 | ENSG00000087191 | PSMC5 | 96.30 | 1.80E-05 | 1.60E-09 | 58.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YOR117W | RPT5 | SGDID:S000005643 | psmB AF_0481 |
Proteasome subunit beta (EC 3.4.25.1) (20S proteasome beta subunit) (Proteasome core protein PsmB) |
3.4.25.1 | Archaeoglobus fulgidus | 6hea_i | Q9P996 | 97.90 | 3.60E-09 | 3.30E-13 | 101.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YOR117W | RPT5 | SGDID:S000005643 | Msed_1672 |
Msed_1672 |
Metallosphaera sedula | 4d81_a | A4YHC5 | 95.30 | 0.00022 | 2.10E-08 | 61.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YOR117W | RPT5 | SGDID:S000005643 | PUP1 YOR157C |
Proteasome subunit beta type-2 (EC 3.4.25.1) (Macropain subunit PUP1) (Multicatalytic endopeptidase complex subunit PUP1) (Proteasome component PUP1) (Proteinase YSCE subunit PUP1) |
3.4.25.1 | Saccharomyces cerevisiae | 6fvt_i | P25043 | 99.20 | 4.20E-15 | 3.60E-19 | 147.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YOR117W | RPT5 | SGDID:S000005643 | TRIP13 PCH2 |
Pachytene checkpoint protein 2 homolog (Human papillomavirus type 16 E1 protein-binding protein) (16E1-BP) (HPV16 E1 protein-binding protein) (Thyroid hormone receptor interactor 13) (Thyroid receptor-interacting protein 13) (TR-interacting protein 13) (TRIP-13) |
Homo sapiens | Pontocerebellar Hypoplasia, Type 3,Mosaic Variegated Aneuploidy Syndrome,Choreatic Disease,Mosaic Variegated Aneuploidy Syndrome 3,Microcephaly,Pontocerebellar Hypoplasia, Type 4,Pontocerebellar Hypoplasia, Type 2a,Pontocerebellar Hypoplasia, Type 5,Mental Retardation And Microcephaly With Pontine And Cerebellar Hypoplasia,Mosaic Variegated Aneuploidy Syndrome 2,Wilms Tumor 1,Pontocerebellar Hypoplasia,Oocyte Maturation Defect 9,Lung Cancer |
6f0x_e | Q15645 | 96.10 | 4.20E-05 | 3.60E-09 | 74.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YOR117W | RPT5 | SGDID:S000005643 | NVL NVL2 |
Nuclear valosin-containing protein-like (NVLp) (Nuclear VCP-like protein) |
Homo sapiens | Cone-Rod Dystrophy 2,Charcot-Marie-Tooth Disease, Axonal, Type 2e |
2x8a_a | O15381 | ENSG00000143748 | NVL | 97.00 | 1.20E-06 | 1.10E-10 | 78.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YOR117W | RPT5 | SGDID:S000005643 | PRE3 YJL001W J1407 |
Proteasome subunit beta type-1 (EC 3.4.25.1) (Macropain subunit PRE3) (Multicatalytic endopeptidase complex subunit PRE3) (Proteasome component PRE3) (Proteinase YSCE subunit PRE3) |
3.4.25.1 | Saccharomyces cerevisiae | 6fvw_h | P38624 | 99.50 | 5.60E-18 | 4.50E-22 | 171.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |