Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
YOR119C | RIO1 | SGDID:S000005645 | PLK3 CNK FNK PRK |
Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Polo-like kinase 3) (PLK-3) (Proliferation-related kinase) |
2.7.11.21 | Homo sapiens | Breast Cancer |
4b6l_a | Q9H4B4 | ENSG00000173846 | PLK3 | 99.10 | 4.70E-15 | 4.20E-19 | 140.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | CHEK2 CDS1 CHK2 RAD53 |
Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2) |
2.7.11.1 | Homo sapiens | Squamous Cell Carcinoma,Cerebral Hemisphere Lipoma,Corpus Callosum Lipoma,Adenoid Cystic Carcinoma,Cowden Syndrome,Cervical Adenoma Malignum,Leiomyosarcoma,Bilateral Breast Cancer,B-Lymphoblastic Leukemia/Lymphoma,Diffuse Midline Glioma, H3 K27m-Mutant,Essential Thrombocythemia,Congenital Heart Defects, Multiple Types, 3,Familial Colorectal Cancer,Leukemia,Inherited Cancer-Predisposing Syndrome,Wilms Tumor 5,Leukemia, Acute Myeloid,Sporadic Breast Cancer,Li-Fraumeni Syndrome 1,Telangiectasis,Basal Cell Carcinoma,Lung Leiomyosarcoma,Prostate Leiomyosarcoma,Cerebellar Disease,Bile Duct Cystadenoma,T-Cell Prolymphocytic Leukemia,Nk-Cell Enteropathy,Ovarian Cancer,Breast Cancer,Hereditary Breast Ovarian Cancer Syndrome,Colorectal Cancer,Li-Fraumeni Syndrome 2,Premature Menopause,Rhabdomyosarcoma,Xeroderma Pigmentosum, Variant Type,Sarcoma,Fanconi Anemia, Complementation Group A,Bone Osteosarcoma,Skin Carcinoma,Gastric Cancer,Breast Adenocarcinoma,Prostate Cancer,Thrombocytopenia,Lynch Syndrome,Esophageal Cancer,Seckel Syndrome,Myelodysplastic Syndrome,Gastric Cancer, Hereditary Diffuse,Tumor Predisposition Syndrome,Cutaneous Telangiectasia And Cancer Syndrome, Familial,Wilms Tumor 1,Autosomal Recessive Cerebellar Ataxia,Lymphoma,Nijmegen Breakage Syndrome,Colitis,Li-Fraumeni Syndrome,Premature Ovarian Failure 1,Ataxia-Telangiectasia,Melanoma, Cutaneous Malignant 1,Lung Cancer,Osteogenic Sarcoma |
3i6u_a | O96017 | ENSG00000183765 | CHEK2 | 99.20 | 1.90E-15 | 1.60E-19 | 153.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | RPS6KA1 MAPKAPK1A RSK1 |
Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1) |
2.7.11.1 | Homo sapiens | Tuberous Sclerosis 2,Tuberous Sclerosis,Cardiomyopathy, Familial Hypertrophic, 4,Disease Of Mental Health,Adrenal Cortical Adenocarcinoma,Dyskeratosis Congenita, Autosomal Dominant 3,Tuberous Sclerosis 1,Coffin-Lowry Syndrome,Polycystic Kidney Disease 3 With Or Without Polycystic Liver Disease |
4nif_d | Q15418 | ENSG00000117676 | RPS6KA1 | 99.10 | 6.40E-15 | 5.60E-19 | 144.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | Camk1 |
Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) |
2.7.11.17 | Rattus norvegicus | 1a06_a | Q63450 | 99.80 | 7.40E-24 | 6.10E-28 | 209.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR119C | RIO1 | SGDID:S000005645 | RAD53 MEC2 SAD1 SPK1 YPL153C P2588 |
Serine/threonine-protein kinase RAD53 (EC 2.7.12.1) (CHEK2 homolog) (Serine-protein kinase 1) |
2.7.12.1 | Saccharomyces cerevisiae | 4pdp_a | P22216 | 99.20 | 3.70E-15 | 3.20E-19 | 146.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR119C | RIO1 | SGDID:S000005645 | MAP4K3 RAB8IPL1 |
Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3) |
2.7.11.1 | Homo sapiens | Adult-Onset Still'S Disease |
5j5t_a | Q8IVH8 | ENSG00000011566 | MAP4K3 | 99.30 | 1.40E-16 | 1.20E-20 | 158.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | Ripk4 Ankrd3 Pkk |
Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-associated protein kinase) (PKC-regulated protein kinase) |
2.7.11.1 | Mus musculus | 5wnj_a | Q9ERK0 | 99.20 | 1.10E-15 | 9.90E-20 | 149.80 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
YOR119C | RIO1 | SGDID:S000005645 | ROCK2 KIAA0619 |
Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2) |
2.7.11.1 | Homo sapiens | Coronary Artery Vasospasm,Dextrocardia,Ureteral Obstruction,Breast Cancer,Tongue Squamous Cell Carcinoma,Hypertension, Essential |
4wot_b | O75116 | ENSG00000134318 | ROCK2 | 99.20 | 4.20E-15 | 3.60E-19 | 149.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | ROCK1 |
Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK) |
2.7.11.1 | Homo sapiens | Coronary Artery Vasospasm,Ocular Hyperemia,Breast Cancer,Pediatric Osteosarcoma,Hutchinson-Gilford Progeria Syndrome,Tetralogy Of Fallot,Hypertension, Essential,Lung Cancer |
3v8s_d | Q13464 | ENSG00000067900 | ROCK1 | 99.10 | 5.70E-15 | 4.90E-19 | 149.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | PHKG2 |
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2) |
2.7.11.19 | Homo sapiens | Glycogen Storage Disease Ixa,Glycogen Storage Disease Ixc,Glycogen Storage Disease,Phosphorylase Kinase Deficiency,Glycogen Storage Disease Due To Liver Phosphorylase Kinase Deficiency,Glycogen Storage Disease Ia,Glycogen Storage Disease, Type Ixd,Glycogen Storage Disease Ix,Glycogen Storage Disease Ixb |
2y7j_c | P15735 | ENSG00000156873 | PHKG2 | 99.30 | 5.00E-16 | 4.40E-20 | 153.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | TLK2 |
Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (HsHPK) (PKU-alpha) (Tousled-like kinase 2) |
2.7.11.1 | Homo sapiens | Pica Disease,Mental Retardation, Autosomal Dominant 57 |
5o0y_a | Q86UE8 | ENSG00000146872 | TLK2 | 99.20 | 2.80E-15 | 2.20E-19 | 159.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | rio2 AF_2426 |
RIO-type serine/threonine-protein kinase Rio2 (AfRio2) (EC 2.7.11.1) |
2.7.11.1 | Archaeoglobus fulgidus | 1zao_a | O30245 | 99.40 | 3.20E-17 | 2.70E-21 | 158.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR119C | RIO1 | SGDID:S000005645 | DAPK1 DAPK |
Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1) |
2.7.11.1 | Homo sapiens | Squamous Cell Carcinoma,Childhood Acute Lymphocytic Leukemia,Lung Cancer Susceptibility 3,Adenoid Cystic Carcinoma,Cholecystitis,Alzheimer Disease,B-Cell Lymphoma,Mixed Oligodendroglioma-Astrocytoma,Transitional Cell Carcinoma,Bladder Cancer,Tuberous Sclerosis 2,Parkinson Disease, Late-Onset,Colorectal Cancer,Pediatric Lymphoma,Oligodendroglioma,Central Neurocytoma,Ischemia,Gastric Cancer,Pancreatic Ductal Adenocarcinoma,Cholangiocarcinoma,Cervical Cancer,Cervical Squamous Cell Carcinoma,Myelodysplastic Syndrome,Nasopharyngeal Carcinoma,Lung Cancer |
2x0g_a | P53355 | ENSG00000196730 | DAPK1 | 99.10 | 4.90E-15 | 4.30E-19 | 144.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | RIOK2 RIO2 |
Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2) |
2.7.11.1 | Homo sapiens | Diamond-Blackfan Anemia,Cecum Adenocarcinoma,Strongyloidiasis,Cecum Carcinoma,Alcohol-Related Neurodevelopmental Disorder |
6fdm_a | Q9BVS4 | ENSG00000058729 | RIOK2 | 99.50 | 3.80E-18 | 3.20E-22 | 167.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | HCK |
Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck) |
2.7.10.2 | Homo sapiens | Leukemia, Chronic Myeloid,Tinea Favosa,Renal Pelvis Adenocarcinoma,Leukemia, Acute Lymphoblastic,Human Immunodeficiency Virus Type 1,Co-Trimoxazole Allergy,Immune Deficiency Disease |
2hck_b | P08631 | ENSG00000101336 | HCK | 99.10 | 5.30E-15 | 4.70E-19 | 149.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | SRK2I 41K OSKL2 SNRK2.3 At5g66880 MUD21.14 |
Serine/threonine-protein kinase SRK2I (EC 2.7.11.1) (OST1-kinase-like 2) (Protein ATHPROKIN B) (SNF1-related kinase 2.3) (SnRK2.3) |
2.7.11.1 | Arabidopsis thaliana | 3uc3_a | Q39193 | 99.20 | 4.00E-15 | 3.50E-19 | 146.90 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | |||
YOR119C | RIO1 | SGDID:S000005645 | AURKA AIK AIRK1 ARK1 AURA AYK1 BTAK IAK1 STK15 STK6 |
Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A) |
2.7.11.1 | Homo sapiens | Endometrial Cancer,Melanoma,Plasma Cell Neoplasm,Uterine Corpus Cancer,Atypical Teratoid Rhabdoid Tumor,Neuroblastoma,Childhood Malignant Schwannoma,Adult Malignant Schwannoma,Bladder Cancer,Laryngeal Squamous Cell Carcinoma,Tetraploidy,Ovarian Cancer,Prostate Neuroendocrine Neoplasm,Breast Cancer,Colorectal Cancer,Endometrial Serous Adenocarcinoma,Hepatocellular Carcinoma,Rhabdomyosarcoma,Gastric Cancer,Prostate Cancer,Cervical Cancer,Lynch Syndrome,Esophageal Cancer,Donohue Syndrome,Colorectal Adenocarcinoma,Myeloma, Multiple,Medulloblastoma,Primary Autosomal Recessive Microcephaly,Lung Cancer,Pancreatic Cancer |
3h10_a | O14965 | ENSG00000087586 | AURKA | 99.10 | 4.60E-15 | 4.20E-19 | 138.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | MAP3K8 COT ESTF |
Mitogen-activated protein kinase kinase kinase 8 (EC 2.7.11.25) (Cancer Osaka thyroid oncogene) (Proto-oncogene c-Cot) (Serine/threonine-protein kinase cot) (Tumor progression locus 2) (TPL-2) |
2.7.11.25 | Homo sapiens | Indolent Plasma Cell Myeloma,Paronychia,Skin Lipoma,Rheumatoid Arthritis,Lung Cancer |
4y85_b | P41279 | ENSG00000107968 | MAP3K8 | 99.10 | 5.60E-15 | 4.90E-19 | 143.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | MAP3K14 NIK |
Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF-kappa-beta-inducing kinase) (HsNIK) (Serine/threonine-protein kinase NIK) |
2.7.11.25 | Homo sapiens | T-Cell Lymphoblastic Leukemia/Lymphoma,Nik Deficiency,Trichohepatoenteric Syndrome 1,Pancreatic Adenosquamous Carcinoma,Pancreatic Ductal Adenocarcinoma,Immunodeficiency 50 |
4idv_c | Q99558 | ENSG00000006062 | MAP3K14 | 99.10 | 4.90E-15 | 4.40E-19 | 145.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | Taok2 Tao2 |
Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2) |
2.7.11.1 | Rattus norvegicus | 1u5r_b | Q9JLS3 | 99.20 | 3.70E-15 | 3.20E-19 | 147.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR119C | RIO1 | SGDID:S000005645 | PHKG1 PHKG |
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1) (EC 2.7.11.26) |
2.7.11.1,2.7.11.19,2.7.11.26 | Oryctolagus cuniculus | 2phk_a | P00518 | 99.20 | 3.90E-15 | 3.50E-19 | 139.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR119C | RIO1 | SGDID:S000005645 | ROCK2 |
Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2) |
2.7.11.1 | Bos taurus | 2f2u_b | Q28021 | 99.20 | 2.90E-15 | 2.50E-19 | 151.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR119C | RIO1 | SGDID:S000005645 | CTHT_0033330 |
CTHT_0033330 |
2.7.11.1 | Chaetomium thermophilum | 4gyi_a | G0S5R3 | 99.70 | 2.40E-21 | 1.90E-25 | 198.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR119C | RIO1 | SGDID:S000005645 | TTK MPS1 MPS1L1 |
Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT) |
2.7.12.1 | Homo sapiens | Polyposis Syndrome, Hereditary Mixed, 1,Hereditary Mixed Polyposis Syndrome,Osteogenesis Imperfecta, Type Xvii,Lung Cancer,Mosaic Variegated Aneuploidy Syndrome 1,Pancreatic Cancer |
5eh0_a | P33981 | ENSG00000112742 | TTK | 99.20 | 3.60E-15 | 3.20E-19 | 138.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | TTN |
Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14) |
2.7.11.1 | Homo sapiens | Muscular Disease,Heart Disease,Constrictive Pericarditis,Congenital Fiber-Type Disproportion,Mitral Valve Insufficiency,Aortic Valve Disease 2,Congenital Structural Myopathy,Myopathy,Amyloidosis,Cardiomyopathy, Dilated, 1e,Syncope,Myofibrillar Myopathy,Atrial Heart Septal Defect,Mitochondrial Dna Depletion Syndrome 12b,Childhood-Onset Progressive Contractures-Limb-Girdle Weakness-Muscle Dystrophy Syndrome,Emery-Dreifuss Muscular Dystrophy,Cortical Thymoma,Muscle Tissue Disease,Morvan'S Fibrillary Chorea,Neuromuscular Disease,Hypertrophic Cardiomyopathy,Familial Isolated Dilated Cardiomyopathy,Rasopathy,Autosomal Dominant Distal Myopathy,Lung Large Cell Carcinoma,Myopathy, Distal, 1,Myositis,Myotonic Dystrophy 1,Systolic Heart Failure,Myopathy, Myofibrillar, 1,Diastolic Heart Failure,Autosomal Recessive Limb-Girdle Muscular Dystrophy,Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2a,Muscular Dystrophy,Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2g,Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2j,Muscular Atrophy,Tibial Muscular Dystrophy,Limb-Girdle Muscular Dystrophy,Arrhythmogenic Right Ventricular Dysplasia, Familial, 1,Epithelial Malignant Thymoma,Hyaline Body Myopathy,Isolated Elevated Serum Creatine Phosphokinase Levels,Noonan Syndrome 1,Newborn Respiratory Distress Syndrome,Thymus Clear Cell Carcinoma,Reducing Body Myopathy,Myocarditis,Atrial Standstill 1,Muscular Dystrophy, Limb-Girdle, Autosomal Recessive 10,Hereditary Proximal Myopathy With Early Respiratory Failure,Dilated Cardiomyopathy,Alcoholic Cardiomyopathy,Lmna-Related Dilated Cardiomyopathy,Thymus Gland Disease,Long Qt Syndrome,Cardiomyopathy, Dilated, 1dd,Heart Conduction Disease,Udd Distal Myopathy - Tibial Muscular Dystrophy,Muscular Dystrophy, Congenital, Lmna-Related,Neuropathy,Perinephritis,Familial Isolated Arrhythmogenic Ventricular Dysplasia, Right Dominant Form,Familial Isolated Arrhythmogenic Ventricular Dysplasia, Biventricular Form,Familial Isolated Arrhythmogenic Ventricular Dysplasia, Left Dominant Form,Myopathy, Myofibrillar, 3,Sick Sinus Syndrome,Multiminicore Disease,Cardiomyopathy, Familial Hypertrophic, 4,Cardiomyopathy, Dilated, 1a,Congestive Heart Failure,Myopathy, Myofibrillar, 4,Left Ventricular Noncompaction 2,Foot Drop,Myopathy, Myofibrillar, 5,Rhabdomyosarcoma,Rigid Spine Muscular Dystrophy 1,Epidermolysis Bullosa Simplex With Muscular Dystrophy,Thymoma,Thymus Cancer,Dendritic Cell Thymoma,Respiratory Failure,Centronuclear Myopathy,Myopathy, Myofibrillar, 9, With Early Respiratory Failure,Cardiomyopathy, Dilated, 1g,Congenital Myasthenic Syndrome,Cardiomyopathy, Familial Hypertrophic, 9,Cardiomyopathy, Dilated, 1h,Orthostatic Intolerance,Emery-Dreifuss Muscular Dystrophy 2, Autosomal Dominant,Lung Squamous Cell Carcinoma,Restrictive Cardiomyopathy,Extrinsic Cardiomyopathy,Lambert-Eaton Myasthenic Syndrome,Arrhythmogenic Right Ventricular Cardiomyopathy,Brugada Syndrome,Muscle Hypertrophy,Salih Myopathy,Nonaka Myopathy,Primary Cutaneous Amyloidosis,Distal Arthrogryposis,Familial Atrial Fibrillation,Hypermethioninemia Due To Adenosine Kinase Deficiency,Atrioventricular Block,Third-Degree Atrioventricular Block,Barth Syndrome,Cardioneuromyopathy With Hyaline Masses And Nemaline Rods,Cardiomyopathy, Familial Hypertrophic, 1,Wolff-Parkinson-White Syndrome,Muscular Dystrophy-Dystroglycanopathy , Type C, 5,Intrinsic Cardiomyopathy,Peripartum Cardiomyopathy,Lipoprotein Quantitative Trait Locus,Atrial Fibrillation,Scoliosis,Muscular Dystrophy, Duchenne Type,Myopathy, Centronuclear, X-Linked,Cardiac Arrest,Inguinal Hernia,Muscular Dystrophy, Limb-Girdle, Autosomal Recessive 2,Myasthenia Gravis,Left Ventricular Noncompaction,Lethal Congenital Contracture Syndrome,Myopathy, Centronuclear, 2,Batten-Turner Congenital Myopathy,Miyoshi Muscular Dystrophy,Tibial Muscular Dystrophy, Tardive,Cardiomyopathy, Dilated, 1b |
1tki_b | Q8WZ42 | ENSG00000155657 | TTN | 99.20 | 2.10E-15 | 1.80E-19 | 146.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | TAOK3 DPK JIK KDS MAP3K18 |
Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3) |
2.7.11.1 | Homo sapiens | Cutaneous T Cell Lymphoma |
6bdn_a | Q9H2K8 | ENSG00000135090 | TAOK3 | 99.10 | 6.20E-15 | 5.40E-19 | 143.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | PAK4 KIAA1142 |
Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4) |
2.7.11.1 | Homo sapiens | Polycystic Kidney Disease 3 With Or Without Polycystic Liver Disease |
4xbr_a | O96013 | ENSG00000130669 | PAK4 | 99.20 | 1.20E-15 | 1.10E-19 | 151.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | CAMK2D CAMKD |
Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17) |
2.7.11.17 | Homo sapiens | Dilated Cardiomyopathy,Cardiomyopathy, Dilated, 1dd |
2wel_a | Q13557 | ENSG00000145349 | CAMK2D | 99.10 | 5.20E-15 | 4.60E-19 | 143.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | CSNK2A2 CK2A2 |
Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1) |
2.7.11.1 | Homo sapiens | Connective Tissue Disease,Neonatal Leukemia,Distal Muscular Dystrophy With Anterior Tibial Onset,Spermatogenic Failure 50,Breast Adenocarcinoma,Theileriasis,Spermatogenic Failure 9 |
6hmq_a | P19784 | ENSG00000070770 | CSNK2A2 | 99.10 | 5.00E-15 | 4.40E-19 | 146.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | MYLK4 SGK085 |
Myosin light chain kinase family member 4 (EC 2.7.11.1) (Sugen kinase 85) (SgK085) |
2.7.11.1 | Homo sapiens | Cardiomyopathy, Familial Restrictive, 2,Deafness, Autosomal Recessive 17,Deafness, Autosomal Recessive 14,Cardiomyopathy, Familial Restrictive, 3 |
2x4f_a | Q86YV6 | ENSG00000145949 | MYLK4 | 99.20 | 2.30E-15 | 2.00E-19 | 149.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | PBL2 APK2A KIN1 At1g14370 F14L17.14 |
Probable serine/threonine-protein kinase PBL2 (EC 2.7.11.1) (PBS1-like protein 2) (Protein kinase 2A) |
2.7.11.1 | Arabidopsis thaliana | 6j5t_d | O49839 | 99.10 | 5.00E-15 | 4.40E-19 | 150.00 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | |||
YOR119C | RIO1 | SGDID:S000005645 | PRKAA2 AMPK AMPK2 |
5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) |
2.7.11.27,2.7.11.31, | Homo sapiens | Hyperglycemia,Hypertrophic Cardiomyopathy,Glycogen Storage Disease,Phosphorylase Kinase Deficiency,Tuberous Sclerosis,Breast Cancer,Ischemia,Aromatase Deficiency,Peutz-Jeghers Syndrome,Body Mass Index Quantitative Trait Locus 11,Type 2 Diabetes Mellitus,Wolff-Parkinson-White Syndrome |
2h6d_a | P54646 | ENSG00000162409 | PRKAA2 | 99.20 | 3.80E-15 | 3.40E-19 | 139.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | WNK3 KIAA1566 PRKWNK3 |
Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase lysine-deficient 3) (Protein kinase with no lysine 3) |
2.7.11.1 | Homo sapiens | Bartter Disease,Renal Tubular Transport Disease,Pseudohypoaldosteronism,Agenesis Of The Corpus Callosum With Peripheral Neuropathy,Arthrogryposis, Distal, Type 3,Liddle Syndrome 1,Hypomagnesemia 4, Renal,Distal Arthrogryposis,Hypertension, Essential,Syndromic X-Linked Intellectual Disability Siderius Type,Gitelman Syndrome |
5o2c_a | Q9BYP7 | ENSG00000196632 | WNK3 | 99.20 | 2.80E-15 | 2.40E-19 | 149.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | PIM1 |
Serine/threonine-protein kinase pim-1 (EC 2.7.11.1) |
2.7.11.1 | Homo sapiens | Retinitis Pigmentosa,Polyploidy,Plasma Protein Metabolism Disease,Primary Central Nervous System Lymphoma,Diamond-Blackfan Anemia,Myeloid Leukemia,Prostate Cancer,Mantle Cell Lymphoma |
3f2a_a | P11309 | ENSG00000137193 | PIM1 | 99.10 | 4.50E-15 | 4.00E-19 | 141.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | STRADA LYK5 STRAD |
STE20-related kinase adapter protein alpha (STRAD alpha) (STE20-related adapter protein) (Serologically defined breast cancer antigen NY-BR-96) |
Homo sapiens | Epilepsy,Polyhydramnios,Endometrial Squamous Cell Carcinoma,Breast Cancer,Megalencephaly,Benign Epilepsy With Centrotemporal Spikes,Scheuermann Disease,Polyhydramnios, Megalencephaly, And Symptomatic Epilepsy |
2wtk_b | Q7RTN6 | ENSG00000266173 | STRADA | 99.10 | 5.50E-15 | 4.80E-19 | 146.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
YOR119C | RIO1 | SGDID:S000005645 | rio1 AF_1804 |
RIO-type serine/threonine-protein kinase Rio1 (AfRio1) (EC 2.7.11.1) |
2.7.11.1 | Archaeoglobus fulgidus | 1zth_c | O28471 | 99.60 | 2.00E-19 | 1.70E-23 | 170.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR119C | RIO1 | SGDID:S000005645 | PLK1 PLK |
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) |
2.7.11.21 | Homo sapiens | Breast Papillomatosis,Squamous Cell Carcinoma,Cornelia De Lange Syndrome,Leukemia, Chronic Myeloid,Gonococcal Keratitis,Leukemia, Acute Myeloid,Trichothiodystrophy 1, Photosensitive,Ovarian Cancer,Breast Cancer,Colorectal Cancer,Microcephaly,Rhabdomyosarcoma,Gastric Cancer,Prostate Cancer,Lung Squamous Cell Carcinoma,Lymphoma, Non-Hodgkin, Familial,Dyskeratosis Congenita, Autosomal Dominant 3,Esophageal Cancer,Brain Glioma,Ataxia-Telangiectasia,Medulloblastoma,Primary Autosomal Recessive Microcephaly,Lung Cancer,Pancreatic Cancer |
4j53_a | P53350 | ENSG00000166851 | PLK1 | 99.20 | 4.00E-15 | 3.60E-19 | 141.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | RIOK1 RIO1 |
Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1) |
2.7.11.1,3.6.3.-, | Homo sapiens | Cecum Adenocarcinoma,Cecum Carcinoma,Alcohol-Related Neurodevelopmental Disorder |
4otp_a | Q9BRS2 | 100.00 | 7.50E-41 | 6.10E-45 | 339.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | ||
YOR119C | RIO1 | SGDID:S000005645 | SNRK KIAA0096 SNFRK |
SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase) |
2.7.11.1 | Homo sapiens | Breast Angiosarcoma,Skin Angiosarcoma,Liver Angiosarcoma,Skin Sarcoma,Lymphangiosarcoma,Breast Sarcoma,Hydrolethalus Syndrome 1,Neuronopathy, Distal Hereditary Motor, Type Viii |
5yks_b | Q9NRH2 | ENSG00000163788 | SNRK | 99.20 | 2.60E-15 | 2.20E-19 | 150.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | SNF1 CAT1 CCR1 GLC2 PAS14 YDR477W D8035.20 |
Carbon catabolite-derepressing protein kinase (EC 2.7.11.1) (Sucrose nonfermentating protein 1) |
2.7.11.1 | Saccharomyces cerevisiae | 2fh9_a | P06782 | 99.20 | 3.60E-15 | 3.30E-19 | 140.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR119C | RIO1 | SGDID:S000005645 | AAK1 KIAA1048 |
AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1) |
2.7.11.1 | Homo sapiens | Parkinson Disease, Late-Onset,Cataract 8, Multiple Types,Hepatitis C Virus,Rabies |
5te0_a | Q2M2I8 | ENSG00000115977 | AAK1 | 99.20 | 2.10E-15 | 1.80E-19 | 147.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YOR119C | RIO1 | SGDID:S000005645 | ROP5C |
ROP5C |
Toxoplasma gondii | 4lv8_a | I6ZQR7 | 99.10 | 6.00E-15 | 5.30E-19 | 145.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YOR119C | RIO1 | SGDID:S000005645 | RIO2 YNL207W N1342 |
Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) |
2.7.11.1 | Saccharomyces cerevisiae | 6fai_l | P40160 | 99.60 | 1.10E-20 | 8.60E-25 | 195.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YOR119C | RIO1 | SGDID:S000005645 | DYRK2 |
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1) |
2.7.12.1 | Homo sapiens | 4azf_a | Q92630 | ENSG00000127334 | DYRK2 | 99.30 | 5.40E-16 | 4.60E-20 | 157.40 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |