| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YOR153W | PDR5 | SGDID:S000005679 | ABCC1 MRP1 |
Multidrug resistance-associated protein 1 (EC 7.6.2.2) (ATP-binding cassette sub-family C member 1) (Glutathione-S-conjugate-translocating ATPase ABCC1) (EC 7.6.2.3) (Leukotriene C(4) transporter) (LTC4 transporter) |
7.6.2.2,7.6.2.3, | Bos taurus | 5uja_a | Q8HXQ5 | 98.70 | 1.40E-12 | 1.60E-16 | 165.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YOR153W | PDR5 | SGDID:S000005679 | ABCC8 SUR |
ATP-binding cassette sub-family C member 8 (Sulfonylurea receptor 1) |
Cricetus cricetus | 5twv_b | Q09427 | 98.60 | 1.20E-11 | 1.30E-15 | 158.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YOR153W | PDR5 | SGDID:S000005679 | pgp-1 K08E7.9 |
Multidrug resistance protein pgp-1 (EC 7.6.2.2) (P-glycoprotein A) (P-glycoprotein-related protein 1) |
7.6.2.2 | Caenorhabditis elegans | 4f4c_a | P34712 | 98.50 | 1.40E-11 | 1.70E-15 | 151.70 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | |||
| YOR153W | PDR5 | SGDID:S000005679 | ABCG2 ABCP BCRP BCRP1 MXR |
Broad substrate specificity ATP-binding cassette transporter ABCG2 (EC 7.6.2.2) (ATP-binding cassette sub-family G member 2) (Breast cancer resistance protein) (CDw338) (Mitoxantrone resistance-associated protein) (Placenta-specific ATP-binding cassette transporter) (Urate exporter) (CD antigen CD338) |
7.6.2.2 | Homo sapiens | Stomach Carcinoma In Situ,Epilepsy,Hyperuricemia,Placental Choriocarcinoma,Gestational Choriocarcinoma,Ocular Cancer,Core Binding Factor Acute Myeloid Leukemia,Nail Disorder, Nonsyndromic Congenital, 1,Sitosterolemia,Erythroplakia,Acute Leukemia,Leukemia, Acute Myeloid,Leukemia, Acute Lymphoblastic,Persistent Fetal Circulation Syndrome,Bilirubin Metabolic Disorder,Gout,Brain Cancer,Diarrhea,Ovarian Cancer,Adult Acute Lymphocytic Leukemia,Breast Cancer,Colorectal Cancer,Hepatocellular Carcinoma,Polyneuropathy Due To Drug,Rhabdomyosarcoma,Gastric Cancer,Breast Adenocarcinoma,Prostate Cancer,Choriocarcinoma,Toxic Encephalopathy,Thrombocytopenia,Multiple Sclerosis,Esophageal Cancer,Uric Acid Concentration, Serum, Quantitative Trait Locus 1,Blood Group, Junior System,Renal Cell Carcinoma, Nonpapillary,Ischiocoxopodopatellar Syndrome With Or Without Pulmonary Arterial Hypertension,Medulloblastoma,Hyperekplexia,Childhood Acute Myeloid Leukemia,Lung Cancer,Pancreatic Cancer |
6hbu_a | Q9UNQ0 | ENSG00000118777 | ABCG2 | 99.80 | 1.30E-25 | 1.60E-29 | 257.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YOR153W | PDR5 | SGDID:S000005679 | ABCA1 ABC1 CERP |
Phospholipid-transporting ATPase ABCA1 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 1) (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1) (Cholesterol efflux regulatory protein) |
7.6.2.1 | Homo sapiens | Heart Disease,Chediak-Higashi Syndrome,Vascular Disease,Familial Hyperlipidemia,Inherited Metabolic Disorder,Diabetes Mellitus,Myopia,Ichthyosis, Congenital, Autosomal Recessive 4a,Cerebrovascular Disease,Homozygous Familial Hypercholesterolemia,Alzheimer Disease,Myocardial Infarction,Pulmonary Alveolar Proteinosis,Stroke, Ischemic,Primary Biliary Cholangitis,Sitosterolemia,Smith-Lemli-Opitz Syndrome,Hypoalphalipoproteinemia,Atherosclerosis Susceptibility,Cardiovascular System Disease,Coronary Heart Disease 5,Splenomegaly,Aortic Atherosclerosis,Xanthomatosis,Colorectal Cancer,Open-Angle Glaucoma,Familial Hypercholesterolemia,Hypolipoproteinemia,Lipid Metabolism Disorder,Stargardt Disease,Lysosomal Acid Lipase Deficiency,Macular Degeneration, Age-Related, 1,Huntington Disease-Like 1,Niemann-Pick Disease,Disease Of Mental Health,Body Mass Index Quantitative Trait Locus 11,Hypoalphalipoproteinemia, Primary, 1,Type 2 Diabetes Mellitus,Malaria,Fetal Akinesia Deformation Sequence 4,Ichthyosis, Congenital, Autosomal Recessive 4b,Hypoalphalipoproteinemia, Primary, 2,Glaucoma, Primary Open Angle,Hypertension, Essential,Lipoprotein Quantitative Trait Locus,Tangier Disease,Autosomal Recessive Congenital Ichthyosis,C Syndrome,Niemann-Pick Disease, Type C1,Scott Syndrome |
5xjy_a | O95477 | ENSG00000165029 | ABCA1 | 99.80 | 1.40E-25 | 1.30E-29 | 298.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YOR153W | PDR5 | SGDID:S000005679 | ABCG8 |
ATP-binding cassette sub-family G member 8 (EC 7.6.2.-) (Sterolin-2) |
7.6.2.- | Homo sapiens | Homozygous Familial Hypercholesterolemia,Sea-Blue Histiocyte Disease,Sitosterolemia,Arcus Corneae,Leber Plus Disease,Cholestasis, Progressive Familial Intrahepatic, 2,Cholelithiasis,Aortic Atherosclerosis,Cholestasis, Progressive Familial Intrahepatic, 3,Familial Hypercholesterolemia,Hypolipoproteinemia,Hemolytic Anemia,Thrombocytopenia,Type 2 Diabetes Mellitus,Gallbladder Disease 4,Cholestasis, Benign Recurrent Intrahepatic, 1,Sitosterolemia 2,Gallbladder Disease,Tangier Disease,Sitosterolemia 1,Progressive Familial Intrahepatic Cholestasis,Cholestasis, Progressive Familial Intrahepatic, 1 |
5do7_b | Q9H221 | ENSG00000143921 | ABCG8 | 99.80 | 5.20E-26 | 6.40E-30 | 262.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YOR153W | PDR5 | SGDID:S000005679 | hisP STM2351 |
Histidine transport ATP-binding protein HisP |
Salmonella typhimurium | 1b0u_a | P02915 | 98.20 | 5.80E-10 | 5.40E-14 | 120.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YOR153W | PDR5 | SGDID:S000005679 | cftr |
Cystic fibrosis transmembrane conductance regulator (EC 5.6.1.6) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (cAMP-dependent chloride channel) |
5.6.1.6 | Danio rerio | 5w81_a | Q1LX78 | 98.40 | 7.40E-11 | 8.20E-15 | 150.20 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | |||
| YOR153W | PDR5 | SGDID:S000005679 | ecfA1 cbiO1 LVIS_1662 |
Energy-coupling factor transporter ATP-binding protein EcfA1 (ECF transporter A component EcfA1) (EC 7.-.-.-) |
Lactobacillus brevis | 4huq_b | Q03PY5 | 98.20 | 2.60E-10 | 3.10E-14 | 115.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YOR153W | PDR5 | SGDID:S000005679 | Abcb1a Abcb4 Mdr1a Mdr3 Pgy-3 Pgy3 |
ATP-dependent translocase ABCB1 (ATP-binding cassette sub-family B member 1A) (MDR1A) (Multidrug resistance protein 1A) (EC 7.6.2.2) (Multidrug resistance protein 3) (P-glycoprotein 3) (Phospholipid transporter ABCB1) (EC 7.6.2.1) |
7.6.2.1,7.6.2.2, | Mus musculus | 5kpd_a | P21447 | 98.10 | 5.90E-10 | 7.20E-14 | 135.90 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
| YOR153W | PDR5 | SGDID:S000005679 | ABCG5 |
ATP-binding cassette sub-family G member 5 (EC 7.6.2.-) (Sterolin-1) |
7.6.2.- | Homo sapiens | Lysosomal And Lipase Deficiency,Short-Rib Thoracic Dysplasia 15 With Polydactyly,Homozygous Familial Hypercholesterolemia,Biliary Tract Disease,Sitosterolemia,Arcus Corneae,Leber Plus Disease,Atherosclerosis Susceptibility,Cholestasis, Progressive Familial Intrahepatic, 2,Cholelithiasis,Aortic Atherosclerosis,Cholestasis, Progressive Familial Intrahepatic, 3,Familial Hypercholesterolemia,Hypolipoproteinemia,Thrombocytopenia,Type 2 Diabetes Mellitus,Cholestasis, Benign Recurrent Intrahepatic, 2,Gallbladder Disease 4,Cholestasis, Benign Recurrent Intrahepatic, 1,Sitosterolemia 2,Hyperlipoproteinemia, Type Iv,Gallbladder Disease,Tangier Disease,Short-Rib Thoracic Dysplasia 1 With Or Without Polydactyly,Sitosterolemia 1,Progressive Familial Intrahepatic Cholestasis,Cholestasis, Progressive Familial Intrahepatic, 1,Niemann-Pick Disease, Type C1 |
5do7_a | Q9H222 | ENSG00000138075 | ABCG5 | 99.90 | 1.80E-29 | 2.20E-33 | 291.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YOR153W | PDR5 | SGDID:S000005679 | Abcc8 |
Abcc8 |
Mesocricetus auratus | 6jb3_b | A0A1U7R319 | 98.60 | 1.10E-11 | 1.20E-15 | 158.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |