YOR212W STE4 / SGDID:S000005738
SGD CSV
Disease Associated
Homo Sapiens
Mus Musculus
Danio Rerio
Drosophila Melanogaster
Caenorhabditis Elegans
Arabidopsis Thaliana
Escherichia Coli
Yeast Systematic Name Yeast Symbol SGDID Analog Name Analog Description EC Organism Disease Structure Uniprot Human ID Human Symbol HHsearch Probability HHsearch E_value HHsearch P_value HHsearch Score Flag Disease related Flag Homo sapiens Flag Mus musculus Flag Danio rerio Flag Drosophila melanogaster Flag Caenorhabditis elegans Flag Arabidopsis thaliana Flag Escherichia coli
YOR212W STE4 SGDID:S000005738
PLRG1
Pleiotropic regulator 1
 Homo sapiens
Poikiloderma With Neutropenia,Cardiac Valvular Dysplasia, X-Linked
 4yvd_a O43660 ENSG00000171566 PLRG1 98.80 1.30E-12 7.40E-17 114.20 1 1 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
SMD1 YGR074W
Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (snRNP core protein D1)
 Saccharomyces cerevisiae
5nrl_h Q02260 98.90 5.80E-13 3.40E-17 120.70 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
TIF34 YMR146C YM9375.16C
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 39 kDa subunit) (eIF-3 39 kDa subunit) (eIF3 p39)
 Saccharomyces cerevisiae
5a5u_i P40217 98.70 3.30E-12 1.90E-16 109.70 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
DAW1 WDR69
Dynein assembly factor with WDR repeat domains 1 (Outer row dynein assembly protein 16 homolog) (WD repeat-containing protein 69)
 Homo sapiens
Primary Ciliary Dyskinesia,Visceral Heterotaxy,Ciliary Dyskinesia, Primary, 1,Ciliary Dyskinesia, Primary, 2,Dextro-Looped Transposition Of The Great Arteries
 5nnz_a Q8N136 ENSG00000123977 DAW1 98.80 8.60E-13 5.10E-17 116.90 1 1 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
prp19 cwf8 SPAC29A4.08c
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Complexed with cdc5 protein 8) (RING-type E3 ubiquitin transferase PRP19)
 2.3.2.27 Schizosaccharomyces pombe
3jb9_u O14011 98.90 3.40E-13 2.00E-17 122.90 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
GNB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
 Bos taurus
1tbg_c P62871 99.30 1.50E-16 8.60E-21 137.40 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
UTP7 KRE31 YER082C
U3 small nucleolar RNA-associated protein 7 (U3 snoRNA-associated protein 7) (U three protein 7)
 Saccharomyces cerevisiae
5wlc_lw P40055 98.80 2.30E-12 1.40E-16 119.50 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
PALB2 FANCN
Partner and localizer of BRCA2
 Homo sapiens
Peritoneum Cancer,Islet Cell Tumor,Cowden Syndrome,Cervical Adenoma Malignum,Fallopian Tube Disease,Fallopian Tube Carcinoma,Bilateral Breast Cancer,Diffuse Gastric Cancer,Fanconi Anemia, Complementation Group R,Inherited Cancer-Predisposing Syndrome,Sporadic Breast Cancer,Basal Cell Carcinoma,B-Lymphoblastic Leukemia/Lymphoma With T,Bap1 Tumor Predisposition Syndrome,Basal Cell Nevus Syndrome,Dysplastic Nevus Syndrome,Fanconi Anemia, Complementation Group J,Fanconi Anemia, Complementation Group Q,Aplastic Anemia,Ovarian Cancer,Breast Cancer,Hereditary Breast Ovarian Cancer Syndrome,Colorectal Cancer,Pancreatic Cancer 3,Fanconi Anemia, Complementation Group O,Anaplastic Ependymoma,Fanconi Anemia, Complementation Group A,Cervical Mucinous Adenocarcinoma,Breast-Ovarian Cancer, Familial 1,Lynch Syndrome,Fanconi Anemia, Complementation Group N,Fanconi Anemia, Complementation Group P,Fanconi Anemia, Complementation Group D1,Female Breast Cancer,Gastric Cancer, Hereditary Diffuse,Tumor Predisposition Syndrome,Tracheoesophageal Fistula With Or Without Esophageal Atresia,Cutaneous Telangiectasia And Cancer Syndrome, Familial,Li-Fraumeni Syndrome,Ovarian Cancer 1,Medulloblastoma,Melanoma, Cutaneous Malignant 1,Pancreatic Cancer
 3eu7_a Q86YC2 ENSG00000083093 PALB2 98.70 6.40E-12 3.80E-16 109.30 1 1 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
WD_REPEATS_REGION domain-containing protein
WD_REPEATS_REGION domain-containing protein
 Oryctolagus cuniculus
3jah_gg G1SJB4 98.70 6.20E-12 3.70E-16 106.40 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
SNRPE
Small nuclear ribonucleoprotein E (snRNP-E) (Sm protein E) (Sm-E) (SmE)
 Homo sapiens
Hypotrichosis,Spinal Muscular Atrophy,Hypotrichosis 11,Hypotrichosis Simplex,Hypotrichosis 8,Hypotrichosis 7,Hypotrichosis 4,Systemic Lupus Erythematosus,Hypotrichosis 6,Microcephalic Osteodysplastic Primordial Dwarfism, Type I
 6id1_e P62304 ENSG00000182004 SNRPE 98.90 6.60E-13 3.90E-17 115.30 1 1 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
PRPF19 NMP200 PRP19 SNEV
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor)
 2.3.2.27 Homo sapiens
Retinitis Pigmentosa 19,Poikiloderma With Neutropenia
 4lg8_a Q9UMS4 ENSG00000110107 PRPF19 98.80 1.20E-12 7.20E-17 113.70 1 1 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
SQT1 YIR012W YIB12W
Ribosome assembly protein SQT1
 Saccharomyces cerevisiae
4zox_a P35184 98.70 4.10E-12 2.40E-16 110.80 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
KLLA0_E24487g
KLLA0_E24487g
 Kluyveromyces lactis
6chg_a Q6CLY5 98.80 1.40E-12 8.20E-17 110.30 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
TVAG_151920
TVAG_151920
 Trichomonas vaginalis
5xyi_g A2ELV7 98.80 1.60E-12 9.50E-17 111.20 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
CDH1 HCT1 YGL003C
APC/C activator protein CDH1 (CDC20 homolog 1) (Homolog of CDC twenty 1)
 Saccharomyces cerevisiae
4bh6_f P53197 98.70 6.90E-12 4.00E-16 105.80 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
TBL1XR1 IRA1 TBLR1
F-box-like/WD repeat-containing protein TBL1XR1 (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) (Transducin beta-like 1X-related protein 1)
 Homo sapiens
Learning Disability,Fitzsimmons Syndrome,Noonan Syndrome 1,Pierpont Syndrome,Central Nervous System Hematologic Cancer,Lipomatosis,West Syndrome,Disease Of Mental Health,Acute Promyelocytic Leukemia,Mental Retardation, Autosomal Dominant 41,Rett Syndrome,Autism
 4lg9_a Q9BZK7 ENSG00000177565 TBL1XR1 98.80 2.00E-12 1.20E-16 113.80 1 1 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
raf1 clr8 cmc1 dos1 SPCC613.12c
Rik1-associated factor 1 (Cryptic loci regulator 8) (De-localization of swi6 protein 1)
 Schizosaccharomyces pombe
4o9d_b O74910 98.70 3.30E-12 2.00E-16 113.40 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
UTP15 YMR093W YM9582.18
U3 small nucleolar RNA-associated protein 15 (U3 snoRNA-associated protein 15) (U three protein 15) (U3 protein 15 required for transcription) (t-UTP15)
 Saccharomyces cerevisiae
5wlc_lj Q04305 98.80 1.60E-12 9.40E-17 119.40 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
SEC27 YGL137W G2827
Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)
 Saccharomyces cerevisiae
4j73_a P41811 98.80 1.70E-12 9.80E-17 109.70 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
SPBPJ4664.04
Putative coatomer subunit alpha (Alpha-coat protein) (Alpha-COP)
 Schizosaccharomyces pombe
4j87_a Q96WV5 98.90 1.70E-13 9.70E-18 116.80 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
smd2 cwf9 SPAC2C4.03c
Small nuclear ribonucleoprotein Sm D2 (Sm-D2) (Complexed with cdc5 protein 9) (snRNP core protein D2)
 Schizosaccharomyces pombe
3jb9_l O14036 98.70 5.70E-12 3.40E-16 108.20 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
Gnb5
Guanine nucleotide-binding protein subunit beta-5 (Gbeta5) (Transducin beta chain 5)
 Mus musculus
2pbi_d P62881 99.30 1.10E-16 6.60E-21 139.20 0 0 1 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
SMX2 SNP2 YFL017W-A YFL017Bw
Small nuclear ribonucleoprotein G (snRNP-G) (Sm protein G) (Sm-G) (SmG)
 Saccharomyces cerevisiae
5zwm_k P40204 98.90 5.80E-13 3.40E-17 120.70 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
TaGB1
TaGB1
 Triticum aestivum
4v7e_bg Q8LNY6 99.00 4.90E-14 2.90E-18 123.20 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
S10_plectin domain-containing protein
S10_plectin domain-containing protein
 Oryctolagus cuniculus
5k0y_t G1T168 98.80 1.90E-12 1.10E-16 110.30 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
SNRPD3
Small nuclear ribonucleoprotein Sm D3 (Sm-D3) (snRNP core protein D3)
 Homo sapiens
Connective Tissue Disease,Spinal Muscular Atrophy,Muscular Atrophy,Lupus Erythematosus,Mixed Connective Tissue Disease,Systemic Lupus Erythematosus
 6qdv_n P62318 ENSG00000100028 SNRPD3 98.70 4.10E-12 2.40E-16 107.20 1 1 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
ASC1 CPC2 YMR116C YM9718.15C
Guanine nucleotide-binding protein subunit beta-like protein (Receptor for activated C kinase) (Receptor of activated protein kinase C 1) (RACK1) (Small ribosomal subunit protein RACK1)
 Saccharomyces cerevisiae
6i7o_o P38011 98.70 4.50E-12 2.60E-16 107.20 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
msl1 pi056 SPBC8D2.09c
Probable U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'')
 Schizosaccharomyces pombe
3jb9_k Q7LL14 98.70 5.10E-12 3.10E-16 114.20 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
CTHT_0055700
Ribosome assembly protein 4 (Notchless protein homolog 1) (Ribosome biogenesis factor RSA4)
 Chaetomium thermophilum
4wjs_a G0SC29 98.80 2.10E-12 1.30E-16 116.80 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
WDR5 BIG3
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
 Homo sapiens
Kleefstra Syndrome,Kabuki Syndrome 1
 2h9l_a P61964 ENSG00000196363 WDR5 98.90 6.10E-13 3.60E-17 114.30 1 1 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
WDR33 WDC146
pre-mRNA 3' end processing protein WDR33 (WD repeat-containing protein 33) (WD repeat-containing protein of 146 kDa)
 Homo sapiens
Atrial Septal Defect 6
 6f9n_b Q9C0J8 ENSG00000136709 WDR33 98.80 1.90E-12 1.10E-16 113.50 1 1 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
RSA4 YCR072C YCR72C
Ribosome assembly protein 4 (Notchless protein homolog 1) (Ribosome biogenesis factor RSA4)
 Saccharomyces cerevisiae
4wju_a P25382 98.90 3.70E-13 2.20E-17 123.20 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
DAW1 ODA16
Dynein assembly factor with WDR repeat domains 1 (Outer row dynein assembly protein 16)
 Chlamydomonas reinhardtii
5mzh_a Q3Y8L7 98.80 1.10E-12 6.40E-17 118.30 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
TUP1 AAR1 AER2 AMM1 CYC9 FLK1 SFL2 UMR7 YCR084C YCR84C
General transcriptional corepressor TUP1 (Flocculation suppressor protein) (Glucose repression regulatory protein TUP1) (Repressor AER2)
 Saccharomyces cerevisiae
1erj_a P16649 99.00 8.60E-14 5.10E-18 123.00 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
pkwA pkw1
Probable serine/threonine-protein kinase PkwA (EC 2.7.11.1)
 2.7.11.1 Thermomonospora curvata
5yzv_b P49695 98.80 1.30E-12 7.60E-17 109.90 0 0 0 0 0 0 0 0
YOR212W STE4 SGDID:S000005738
Guanine nucleotide-binding protein subunit beta-like protein
Guanine nucleotide-binding protein subunit beta-like protein
 Leishmania donovani
5t2a_7 Q9BIJ5 98.70 3.80E-12 2.20E-16 107.60 0 0 0 0 0 0 0 0