| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YPL115C | BEM3 | SGDID:S000006036 | BEM3 YPL115C LPH12C |
GTPase-activating protein BEM3 (Bud emergence protein 3) |
Saccharomyces cerevisiae | 6fsf_a | P32873 | 99.90 | 4.20E-31 | 4.50E-35 | 277.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPL115C | BEM3 | SGDID:S000006036 | ARHGAP11A KIAA0013 |
Rho GTPase-activating protein 11A (Rho-type GTPase-activating protein 11A) |
Homo sapiens | Benign Epilepsy With Centrotemporal Spikes,Prader-Willi Syndrome,Chromosome 15q13.3 Deletion Syndrome |
3eap_a | Q6P4F7 | ENSG00000198826 | ARHGAP11A | 99.70 | 4.20E-23 | 4.10E-27 | 220.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YPL115C | BEM3 | SGDID:S000006036 | CHN1 ARHGAP2 CHN |
N-chimaerin (A-chimaerin) (Alpha-chimerin) (N-chimerin) (NC) (Rho GTPase-activating protein 2) |
Homo sapiens | Exotropia,Anisometropia,Hypertropia,Accommodative Esotropia,Esotropia,Hypotropia,Duane Retraction Syndrome,Binocular Vision Disease,Abnormal Retinal Correspondence,Autosomal Dominant Robinow Syndrome,Ocular Motility Disease,Dandy-Walker Syndrome,Sensorineural Hearing Loss,Night Blindness,Suppression Amblyopia,Amblyopia,Ametropic Amblyopia,Diaphragmatic Eventration,Diaphragm Disease,Paralytic Squint,Partial Third-Nerve Palsy,Abducens Nerve Disease,Tukel Syndrome,Hydronephrosis,Cleft Palate, Isolated,Duane Retraction Syndrome 2,Duane Retraction Syndrome 1,Strabismus,Nonaka Myopathy,Robinow Syndrome, Autosomal Dominant 2,Marden-Walker Syndrome,Duane-Radial Ray Syndrome,Laryngomalacia,Robinow Syndrome,Congenital Ptosis |
2osa_a | P15882 | ENSG00000128656 | CHN1 | 99.70 | 5.50E-22 | 5.90E-26 | 197.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YPL115C | BEM3 | SGDID:S000006036 | RALBP1 RLIP1 RLIP76 |
RalA-binding protein 1 (RalBP1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase) (Ral-interacting protein 1) |
Homo sapiens | Lung Cancer |
2mbg_a | Q15311 | ENSG00000017797 | RALBP1 | 99.80 | 1.20E-24 | 1.20E-28 | 231.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YPL115C | BEM3 | SGDID:S000006036 | ARHGAP32 GRIT KIAA0712 RICS |
Rho GTPase-activating protein 32 (Brain-specific Rho GTPase-activating protein) (GAB-associated Cdc42/Rac GTPase-activating protein) (GC-GAP) (GTPase regulator interacting with TrkA) (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS) (RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling) (p200RhoGAP) (p250GAP) |
Homo sapiens | Neuroblastoma,Borna Disease,Chromosome 17q23.1-Q23.2 Deletion Syndrome,Disease Of Mental Health,Bartter Syndrome, Type 2, Antenatal,Johanson-Blizzard Syndrome,Jacobsen Syndrome |
3iug_a | A7KAX9 | ENSG00000134909 | ARHGAP32 | 99.70 | 1.80E-21 | 1.80E-25 | 200.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YPL115C | BEM3 | SGDID:S000006036 | ARHGAP35 GRF1 GRLF1 KIAA1722 P190A p190ARHOGAP |
Rho GTPase-activating protein 35 (Glucocorticoid receptor DNA-binding factor 1) (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A) |
Homo sapiens | 3fk2_a | Q9NRY4 | ENSG00000160007 | ARHGAP35 | 99.80 | 1.60E-23 | 1.60E-27 | 220.60 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| YPL115C | BEM3 | SGDID:S000006036 | ARHGAP1 CDC42GAP RHOGAP1 |
Rho GTPase-activating protein 1 (CDC42 GTPase-activating protein) (GTPase-activating protein rhoGAP) (Rho-related small GTPase protein activator) (Rho-type GTPase-activating protein 1) (p50-RhoGAP) |
Homo sapiens | Noma,Microphthalmia,Dent Disease 1,Non-Syndromic X-Linked Intellectual Disability,Lowe Oculocerebrorenal Syndrome |
1am4_b | Q07960 | ENSG00000175220 | ARHGAP1 | 99.70 | 5.30E-22 | 5.70E-26 | 198.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YPL115C | BEM3 | SGDID:S000006036 | DLC1 ARHGAP7 KIAA1723 STARD12 |
Rho GTPase-activating protein 7 (Deleted in liver cancer 1 protein) (DLC-1) (HP protein) (Rho-type GTPase-activating protein 7) (START domain-containing protein 12) (StARD12) (StAR-related lipid transfer protein 12) |
Homo sapiens | Neural Tube Closure Defect,Colorectal Cancer,Hepatocellular Carcinoma,Neural Tube Defects,Hyperoxaluria, Primary, Type Ii |
3kuq_a | Q96QB1 | ENSG00000164741 | DLC1 | 99.60 | 1.00E-20 | 1.00E-24 | 195.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YPL115C | BEM3 | SGDID:S000006036 | RGD1 YBR260C YBR1728 |
RHO GTPase-activating protein RGD1 (RhoGAP) (Related GAP domain protein 1) |
Saccharomyces cerevisiae | 5my3_a | P38339 | 99.70 | 1.80E-21 | 1.90E-25 | 200.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPL115C | BEM3 | SGDID:S000006036 | Arhgap12 |
Rho GTPase-activating protein 12 (Rho-type GTPase-activating protein 12) |
Mus musculus | 6gvc_q | Q8C0D4 | 99.70 | 2.10E-22 | 2.20E-26 | 207.70 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | ||||
| YPL115C | BEM3 | SGDID:S000006036 | PIK3R1 |
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha) |
Bos taurus | 6d85_a | P23727 | 99.50 | 3.70E-19 | 4.00E-23 | 176.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPL115C | BEM3 | SGDID:S000006036 | ARHGAP15 BM-024 BM-030 BM-046 |
Rho GTPase-activating protein 15 (ArhGAP15) (Rho-type GTPase-activating protein 15) |
Homo sapiens | Diverticulitis,Diverticulitis Of Colon,Meier-Gorlin Syndrome 2,Bladder Squamous Cell Carcinoma,Mowat-Wilson Syndrome,Epilepsy, Idiopathic Generalized 9 |
3byi_b | Q53QZ3 | ENSG00000075884 | ARHGAP15 | 99.70 | 4.00E-22 | 4.10E-26 | 202.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YPL115C | BEM3 | SGDID:S000006036 | PIK3R2 |
Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta) |
Homo sapiens | Endometrial Cancer,Cowden Syndrome,Plasma Cell Neoplasm,Cowden Syndrome 1,Congenital Lipomatous Overgrowth, Vascular Malformations, And Epidermal Nevi,Nevus, Epidermal,Polymicrogyria,Endometrial Adenocarcinoma,Breast Cancer,Colorectal Cancer,Hepatocellular Carcinoma,Megalencephaly-Capillary Malformation-Polymicrogyria Syndrome,Hydrocephalus,Megalencephaly,Immunodeficiency 14,Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome 1,Polydactyly,Prostate Cancer,Proteus Syndrome,Erythrocytosis, Familial, 1,Myeloma, Multiple,Lung Cancer |
2xs6_a | O00459 | ENSG00000105647 | PIK3R2 | 99.60 | 4.40E-20 | 4.50E-24 | 188.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YPL115C | BEM3 | SGDID:S000006036 | ARHGAP20 KIAA1391 |
Rho GTPase-activating protein 20 (Rho-type GTPase-activating protein 20) |
Homo sapiens | 3msx_b | Q9P2F6 | ENSG00000137727 | ARHGAP20 | 99.70 | 3.20E-22 | 3.30E-26 | 199.90 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| YPL115C | BEM3 | SGDID:S000006036 | MYO9B MYR5 |
Unconventional myosin-IXb (Unconventional myosin-9b) |
Homo sapiens | Refractory Celiac Disease,Dermatitis Herpetiformis,Ulcerative Colitis,Celiac Disease 4,Inflammatory Bowel Disease,Inflammatory Bowel Disease 5,Inflammatory Bowel Disease 6,Colitis,Jejunoileitis,Celiac Disease 1 |
5c5s_a | Q13459 | ENSG00000099331 | MYO9B | 99.70 | 3.90E-23 | 4.00E-27 | 213.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YPL115C | BEM3 | SGDID:S000006036 | RACGAP1 KIAA1478 MGCRACGAP |
Rac GTPase-activating protein 1 (Male germ cell RacGap) (MgcRacGAP) (Protein CYK4 homolog) (CYK4) (HsCYK-4) |
Homo sapiens | Uterine Body Mixed Cancer,Uterine Carcinosarcoma,Cataract 36 |
2ovj_a | Q9H0H5 | ENSG00000161800 | RACGAP1 | 99.60 | 1.30E-19 | 1.40E-23 | 180.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YPL115C | BEM3 | SGDID:S000006036 | Arhgap35 Grlf1 P190A p190ARHOGAP |
Rho GTPase-activating protein 35 (GAP-associated protein p190) (Glucocorticoid receptor DNA-binding factor 1) |
Rattus norvegicus | 5irc_a | P81128 | 99.70 | 1.30E-22 | 1.40E-26 | 203.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YPL115C | BEM3 | SGDID:S000006036 | ARAP3 CENTD3 |
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 (Centaurin-delta-3) (Cnt-d3) |
Homo sapiens | Gastrointestinal Anthrax,Oropharyngeal Anthrax |
5jd0_a | Q8WWN8 | ENSG00000120318 | ARAP3 | 99.70 | 4.00E-21 | 4.10E-25 | 195.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |